UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	rabn-5	F01F1.4	0	chrIII 5,865,475	C. elegans RABN-5 protein; contains similarity to Pfam domains PF09311 (Rab5 binding) , PF01363 (FYVE zinc finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002867 (Zinc finger, C6HC-type), IPR015390 (Rabaptin, GTPase-Rab5 binding), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
2	sec-10	C33H5.9	n/a	chrIV 7,780,928	C. elegans SEC-10 protein; contains similarity to Pfam domain PF07393 Exocyst complex component Sec10 contains similarity to Interpro domain IPR009976 (Exocyst complex component Sec10)
3	Y57G11C.4	Y57G11C.4	n/a	chrIV 14,766,103	contains similarity to Pfam domain PF05008 Vesicle transport v-SNARE protein contains similarity to Interpro domains IPR000727 (Target SNARE coiled-coil region), IPR007705 (Vesicle transport v-SNARE)
4	T20F5.3	T20F5.3	n/a	chrI 3,910,087	contains similarity to Pfam domain PF01765 Ribosome recycling factor contains similarity to Interpro domains IPR002661 (Ribosome recycling factor), IPR001669 (Arginine repressor)
5	D2007.4	D2007.4	n/a	chrIII 8,145,419	contains similarity to Drosophila melanogaster Flybase gene name is mRpL18-PA;; FLYBASE:CG12373
6	F35H12.4	F35H12.4	n/a	chrX 922,380	contains similarity to Pfam domain PF00454 Phosphatidylinositol 3- and 4-kinase contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000403 (Phosphatidylinositol 3- and 4-kinase, catalytic), IPR015433 (Phosphatidylinositol Kinase)
7	ehbp-1	F25B3.1	n/a	chrV 9,553,309	C. elegans EHBP-1 protein; contains similarity to Pfam domain PF00307 Calponin homology (CH) domain contains similarity to Interpro domains IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding)
8	F54C9.9	F54C9.9	n/a	chrII 8,579,712	contains similarity to Pfam domain PF05178 Krr1 family contains similarity to Interpro domain IPR007851 (Kri1)
9	smg-5	W02D3.8	n/a	chrI 6,735,096	smg-5 encodes a novel protein that contains two N-terminal tetratricopeptide (TPR) repeats and a C-terminal PINc domain found in nucleotide-binding proteins; SMG-5 is a component of the nonsense-mediated mRNA decay (NMD) pathway and likely functions in regulation of dephosphorylation of SMG-2, the C. elegans UPF1 ortholog, an ATPase and RNA helicase required for NMD in worms, yeast, and mammals; SMG-5 physically interacts with SMG-7, SMG-2, and the PAA-1 and LET-92 structural and catalytic subunits, respectively, of a protein phosphatase 2A (PP2A), suggesting that SMG-5 may function to direct SMG-2 to a PP2A phosphatase that regulates its activity in vivo; SMG-5 also interacts, in vivo, with components of the RNA interference (RNAi) pathway, suggesting a potential link between RNAi and NMD; SMG-5::GFP fusion proteins localize to both the nucleus and the cytoplasm.
10	C50F7.4	C50F7.4	n/a	chrIV 7,729,765	contains similarity to Pfam domains PF08442 (ATP-grasp domain) , PF00549 (CoA-ligase) contains similarity to Interpro domains IPR013650 (ATP-grasp fold, succinyl-CoA synthetase-type), IPR005811 (ATP-citrate lyase/succinyl-CoA ligase), IPR005809 (Succinyl-CoA synthetase, beta subunit), IPR013815 (ATP-grasp fold, subdomain 1), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR013816 (ATP-grasp fold, subdomain 2), IPR016102 (Succinyl-CoA synthetase-like)
11	C34B2.5	C34B2.5	n/a	chrI 10,675,986	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013026 (Tetratricopeptide region)
12	ula-1	C26E6.8	n/a	chrIII 4,919,320	The ula-1 gene encodes a component of the enzyme that activates NED-8, which in turn is a ubiquitin-like protein whose conjugating enzyme is UBC-12.
13	C43D7.4	C43D7.4	n/a	chrV 19,322,158	contains similarity to Saccharomyces cerevisiae Protein of unknown function, rich in asparagine residues; SGD:YDL167C
14	eri-3	W09B6.3	n/a	chrII 1,125,668	C. elegans ERI-3 protein ;
15	F55H12.2	F55H12.2	n/a	chrI 8,868,112	contains similarity to Interpro domain IPR000242 (Tyrosine specific protein phosphatase)
16	C32D5.3	C32D5.3	n/a	chrII 6,319,574	C32D5.3 encodes an ortholog of ROLLING BLACKOUT (RBO; also called CMP44E or STAMPHA), a eukaryotic protein required for sustained phospholipase C activity during Drosophila phototransduction; RBO homologs have two predicted transmembrane helices, are significantly similar to several acylglycerol lipases, and share motifs characteristic of carboxyesterases and lipases.
17	nhr-177	F16B4.1	n/a	chrV 1,611,519	C. elegans NHR-177 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
18	D2085.6	D2085.6	n/a	chrII 8,660,679	D2085.6 is orthologous to the human gene CLASS A GLCNAC-INOSITOL PHOSPHOLIPID ASSEMBLY PROTEIN (PIGA; OMIM:311770), which when mutated leads to paroxysmal nocturnal hemoglobinuria.
19	F25G6.9	F25G6.9	n/a	chrV 8,567,613	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
20	ddb-1	M18.5	n/a	chrIV 12,117,957	M18.5 is orthologous to the human gene DAMAGE-SPECIFIC DNA BINDING PROTEIN 1 (127KD) (DDB1; OMIM:600045), which when mutated leads to disease.
21	srw-32	K03D7.11	n/a	chrV 17,509,470	C. elegans SRW-32 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
22	moc-1	T06H11.4	n/a	chrX 10,137,338	moc-1 encodes an ortholog of human GEPHYRIN (GPHN; OMIM:603930), which when mutated leads to molybdenum cofactor (MoCo) deficiency; MOC-1 is also paralogous to LIN-46.
23	F43G9.10	F43G9.10	n/a	chrI 8,639,367	contains similarity to Pfam domain PF06991 Micro-fibrillar-associated protein 1 C-terminus contains similarity to Interpro domains IPR009730 (Micro-fibrillar-associated 1, C-terminal), IPR000533 (Tropomyosin)
24	CD4.8	CD4.8	n/a	chrV 5,600,286	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
25	smp-2	D1037.2	n/a	chrI 3,669,414	C. elegans SMP-2 protein; contains similarity to Pfam domain PF01403 Sema domain contains similarity to Interpro domains IPR001627 (Semaphorin/CD100 antigen), IPR003659 (Plexin/semaphorin/integrin), IPR016201 (Plexin-like fold), IPR015943 (WD40/YVTN repeat-like)
26	F28C6.8	F28C6.8	n/a	chrII 8,607,222	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
27	clk-2	C07H6.6	n/a	chrIII 7,516,797	The clk-2 gene encodes an ortholog of the S. cerevisiae telomere length-regulating protein Tel2p that has been shown to bind a number of DNA structures in vitro, including single-, double- and four-stranded DNA; in C. elegans, CLK-2 activity is required for the DNA damage and S phase replication checkpoints, for embryonic development, and for normal biological rhythms and life span; a functional CLK-2::GFP fusion protein is detected exclusively in the cytoplasm of somatic tissues.
28	K10C8.1	K10C8.1	n/a	chrV 12,693,876	contains similarity to Pfam domain PF04857 CAF1 family ribonuclease contains similarity to Interpro domains IPR006941 (Ribonuclease CAF1), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
29	K09E3.2	K09E3.2	n/a	chrX 17,117,739
30	T12E12.2	T12E12.2	n/a	chrIV 5,546,641	contains similarity to Pfam domain PF00385 'chromo' (CHRromatin Organisation MOdifier) domain contains similarity to Interpro domains IPR000953 (Chromo domain), IPR016197 (Chromo domain-like)
31	T01G1.3	T01G1.3	n/a	chrIV 11,368,676	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR000694 (Proline-rich region), IPR002110 (Ankyrin), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
32	F45E4.11	F45E4.11	n/a	chrIV 7,652,864	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
33	spd-3	H34C03.1	n/a	chrIV 6,763,933	C. elegans SPD-3 protein ;
34	T26E3.4	T26E3.4	n/a	chrI 12,666,969	contains similarity to Pfam domain PF05773 RWD domain contains similarity to Interpro domains IPR006575 (RWD), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like)
35	C35A5.3	C35A5.3	n/a	chrV 10,500,362	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
36	K02E7.2	K02E7.2	n/a	chrII 1,080,452
37	F19F10.9	F19F10.9	n/a	chrV 7,573,793	The F19F10.9 gene encodes a homolog of the human SART1 gene, which encodes a protein recognised by IgE that may be involved in atopic disease.
38	exoc-7	C43E11.8	n/a	chrI 4,245,201	C. elegans EXOC-7 protein; contains similarity to Pfam domain PF03081 Exo70 exocyst complex subunit contains similarity to Interpro domain IPR004140 (Exo70 exocyst complex subunit)
39	tre-3	W05E10.4	n/a	chrV 11,712,817	tre-3 encodes one of four putative trehalases in C. elegans of unknown function, as RNAi analysis has not produced an obvious phenotype; expressed throughout development.
40	ergo-1	R09A1.1	n/a	chrV 1,013,580	C. elegans ERGO-1 protein; contains similarity to Pfam domains PF02170 (PAZ domain) , PF02171 (Piwi domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
41	gro-1	ZC395.6	n/a	chrIII 5,266,087	C. elegans GRO-1 protein; contains similarity to Pfam domain PF01715 IPP transferase contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR002627 (tRNA isopentenyltransferase), IPR003593 (AAA+ ATPase, core), IPR011593 (Isopentenyl transferase-like), IPR007087 (Zinc finger, C2H2-type)
42	C50E3.5	C50E3.5	n/a	chrV 7,591,348	contains similarity to Interpro domain IPR008108 (Type III secretion system outer membrane, B protein)
43	F55G1.9	F55G1.9	n/a	chrIV 7,476,741	contains similarity to Pfam domain PF03807 NADP oxidoreductase coenzyme F420-dependent contains similarity to Interpro domains IPR004455 (NADP oxidoreductase, coenzyme F420-dependent), IPR000304 (Delta 1-pyrroline-5-carboxylate reductase), IPR016040 (NAD(P)-binding)
44	ZK1098.4	ZK1098.4	n/a	chrIII 9,543,651	contains similarity to Pfam domain PF01008 Initiation factor 2 subunit family contains similarity to Interpro domain IPR000649 (Initiation factor 2B related)
45	F52B5.3	F52B5.3	n/a	chrI 8,321,160	The F52B5.3 gene encodes a DEAH helicase orthologous to the Drosophila SpindleE protein.
46	C16B8.2	C16B8.2	n/a	chrX 3,963,843
47	F55A3.2	F55A3.2	n/a	chrI 10,795,710	contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR015880 (Zinc finger, C2H2-like)
48	cyp-25A2	C36A4.2	n/a	chrIII 3,836,163	C. elegans CYP-25A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
49	F13B6.2	F13B6.2	n/a	chrIV 7,459,793
50	F39B2.3	F39B2.3	n/a	chrI 14,788,812	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)