UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	gpa-3	E02C12.5	0	chrV 9,358,223	gpa-3 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that affects dauer formation, water-soluble chemoattraction and chemoaversion, and volatile chemoattraction; it is expressed in amphid and phasmid neurons and some interneurons.
2	fbxa-3	T08E11.7	n/a	chrII 1,819,483	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
3	F13E9.10	F13E9.10	n/a	chrIV 10,885,597	contains similarity to Arabidopsis thaliana Similarity to unknown protein (Hypothetical protein).; TR:Q9FFB3
4	M01F1.7	M01F1.7	n/a	chrIII 3,525,420	M01F1.7 encodes a phosphatidylinositol transfer protein, with a C-terminal DDHD domain, that is orthologous to RETINAL DEGENERATION B (RDGB) in D. melanogaster, as well as other orthologs in mammals (NIR1-3); M01F1.7 is expressed in the egg membrane, the germline, the spermatheca and three pairs of head neurons; while M01F1.7 would be expected to mediate PIP(2) signalling in either neuronal function or cytokinesis, it has not yet had a published mutant phenotype, and has no obvious function in mass RNAi assays.
5	T03G11.3	T03G11.3	n/a	chrX 5,175,968	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
6	fbxa-115	Y113G7B.3	n/a	chrV 20,186,739	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
7	F20D6.8	F20D6.8	n/a	chrV 8,166,494	contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
8	gst-12	F37B1.2	n/a	chrII 13,617,244	C. elegans GST-12 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
9	ins-35	K02E2.4	n/a	chrV 20,371,307	ins-35 encodes one of several insulin-related peptides.
10	Y75B8A.11	Y75B8A.11	n/a	chrIII 12,188,150	contains similarity to Lymnaea stagnalis Neuropeptide Y precursor.; TR:Q9U0S9
11	C01B10.7	C01B10.7	n/a	chrIV 6,638,773	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
12	pbs-6	C02F5.9	n/a	chrIII 8,243,577	The pbs-6 gene encodes a homolog of mammalian PSMB1.
13	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
14	pqn-25	D1044.3	n/a	chrIII 5,510,853	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
15	nhr-220	T19H12.8	n/a	chrV 4,883,423	C. elegans NHR-220 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
16	C35A11.1	C35A11.1	n/a	chrV 5,406,834	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
17	T24A6.7	T24A6.7	n/a	chrV 3,525,734	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
18	F47G4.5	F47G4.5	n/a	chrI 14,061,493	F47G4.5 encodes a paralog of MEI-2 that, like MEI-2, binds MEI-1 in vitro; F47G4.5 might thus be an alternative ligand of MEI-1 in vivo.
19	pgp-10	C54D1.1	n/a	chrX 7,162,476	pgp-10 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-10 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-10 activity via RNAi results in no obvious defects, the exact role of pgp-10 in C. elegans development and/or behavior is not yet known; pgp-10 promoter-gfp fusion proteins are expressed in larvae and adults in the intestine and hypodermis.
20	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
21	hst-3.1	F40H3.5	n/a	chrII 6,168,467	C. elegans HST-3.1 protein; contains similarity to Pfam domain PF00685 Sulfotransferase domain contains similarity to Interpro domain IPR000863 (Sulphotransferase)
22	Y69H2.2	Y69H2.2	n/a	chrV 18,632,391	contains similarity to Pfam domains PF00008 (EGF-like domain) (5), PF00858 (Amiloride-sensitive sodium channel) , PF07974 (EGF-like domain) (2)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR001873 (Na+ channel, amiloride-sensitive)
23	nhr-120	C25B8.6	n/a	chrX 6,638,552	C. elegans NHR-120 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	F40F9.10	F40F9.10	n/a	chrV 9,712,554	contains similarity to Pfam domain PF02475 Met-10+ like-protein contains similarity to Interpro domain IPR003402 (Protein of unknown function Met10)
25	cav-2	C56A3.7	n/a	chrV 13,558,462	cav-2 encodes one of two C. elegans proteins related to caveolins, integral transmembrane proteins that are believed to function in regulation of signal transduction and that are the major component of caveolae, specialized lipid rafts found in the plasma membrane of most cell types; as loss of cav-2 function via large-scale RNA-mediated interference (RNAi) screens does not result in any obvious abnormalities, the role of cav-2 in C. elegans development and/or behavior is not yet known; cav-2 mRNA is expressed in eggs and mixed stage populations.
26	dhs-16	C10F3.2	n/a	chrV 5,984,592	dhs-16 encodes a short-chain dehydrogenase predicted to be mitochondrial.
27	K10C8.2	K10C8.2	n/a	chrV 12,691,417	K10C8.2 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that K10C8.2 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
28	F07E5.9	F07E5.9	n/a	chrII 2,077,849	contains similarity to Interpro domain IPR016160 (Aldehyde dehydrogenase, conserved site)
29	F42G8.5	F42G8.5	n/a	chrIV 8,137,753
30	C09F12.2	C09F12.2	n/a	chrX 11,055,383	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23C46
31	F28D1.6	F28D1.6	n/a	chrIV 12,384,958	contains similarity to Neurospora crassa ATP-dependent RNA helicase dbp-8 (EC 3.6.1.-).; SW:Q7RYZ7
32	F56F10.2	F56F10.2	n/a	chrX 861,193	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
33	F16H11.2	F16H11.2	n/a	chrX 4,662,854	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23LR2
34	snb-1	T10H9.4	n/a	chrV 6,656,014	The snb-1 gene encodes synaptobrevin, a synaptic vesicle protein orthologous to human vesicle-associated membrane protein 1 (VAMP1 OMIM:185880) and 2 (VAMP2 OMIM:185881), and is required for viability and synaptic transmission; SNB-1 is likely to play a role in vesicle docking and/or fusion and is expressed in neurons where it colocalizes with synaptic vesicle proteins RAB-3 and synaptotagmin.
35	R08F11.7	R08F11.7	n/a	chrV 3,791,935	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal)
36	sru-40	R07B5.3	n/a	chrV 9,833,347	C. elegans SRU-40 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
37	glr-1	C06E1.4	n/a	chrIII 8,586,335	glr-1 encodes an AMPA (non-NMDA)-type ionotropic glutamate receptor subunit; GLR-1 activity is required for mediating the behavioral response to light nose touch and the frequency with which animals change locomotory direction in response to sensory cues such as food; GLR-1 and GLR-2, a second AMPA-type ionotropic glutatmate receptor, can interact to form functional heteromeric channels; GLR-1 is expressed in motorneurons and interneurons, including four of the five pairs of command interneurons that are required for locomotory control; in the ventral nerve cord and nerve ring, GLR-1 localizes to perinuclear structures in cell bodies and to punctate structures that appear to be glutamatergic postsynaptic specializations; proper GLR-1 localization in the anterior ventral nerve cord of older larvae and adults requires activity of the class I PDZ protein LIN-10; GLR-1 is ubiquitinated in vivo and its abundance at postsynaptic elements, which may influence postsynaptic strength, is regulated by ubiquitination.
38	K08F9.3	K08F9.3	n/a	chrV 15,143,291	contains similarity to Pfam domains PF00168 (C2 domain) (3), PF08165 (FerA (NUC095) domain) , PF08150 (FerB (NUC096) domain) contains similarity to Interpro domains IPR012561 (FerB), IPR006614 (Dysferlin, C-terminal), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR012560 (FerA), IPR006613 (Dysferlin, N-terminal), IPR000008 (C2 calcium-dependent membrane targeting)
39	F22D6.8	F22D6.8	n/a	chrI 7,099,204
40	F59F5.5	F59F5.5	n/a	chrX 10,547,442	contains similarity to Actinobacillus pleuropneumoniae KDO transferase.; TR:Q9AIE5
41	Y45F10B.12	Y45F10B.12	n/a	chrIV 13,587,824	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
42	M60.6	M60.6	n/a	chrX 8,250,273
43	R04E5.7	R04E5.7	n/a	chrX 8,797,318
44	srz-18	F46B3.11	n/a	chrV 20,622,846	C. elegans SRZ-18 protein; contains similarity to Interpro domain IPR001036 (Acriflavin resistance protein)
45	egl-36	R07A4.1	n/a	chrX 10,739,267	egl-36 encodes a Shaw-type voltage-gated potassium channel that regulates egg laying and defecation; expression of egl-36::gfp reporters is observed in several different cell types including muscle cells such as the uterine and vulval egg-laying muscles, sensory, motor and interneurons, and the distal tip cells of the gonad; when expressed in a heterologous system, EGL-36 exhibits channel activity.
46	fbxa-10	T12B5.3	n/a	chrIII 953,160	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
47	B0457.2	B0457.2	n/a	chrII 8,925,501	contains similarity to Homo sapiens Isoform 8 of Elastin precursor; ENSEMBL:ENSP00000369958
48	F13A2.4	F13A2.4	n/a	chrV 4,399,097
49	egrh-1	C27C12.2	n/a	chrX 14,847,486	C27C12.2 is orthologous to the human gene BA436D10.3 (EARLY GROWTH RESPONSE 2 (KROX-20 (DROSOPHILA) HOMOLOG)) (EGR2; OMIM:129010), which when mutated leads to disease.
50	T23F4.2	T23F4.2	n/a	chrII 1,164,528