UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ttr-40	E02C12.4	6e-82	chrV 9,354,969	C. elegans TTR-40 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
2	srt-34	F54E2.6	n/a	chrV 2,817,549	C. elegans SRT-34 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
3	M02B7.5	M02B7.5	n/a	chrIV 3,813,489	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) , PF01369 (Sec7 domain) contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR000904 (SEC7-like)
4	twk-36	R12G8.2	n/a	chrV 17,745,322	C. elegans TWK-36 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
5	F28B1.4	F28B1.4	n/a	chrV 17,056,226	contains similarity to Archaeoglobus fulgidus Ferredoxin (FDX-2).; TR:O30071
6	acc-3	F55D10.5	n/a	chrX 4,725,216	C. elegans ACC-3 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR001390 (Gamma-aminobutyric-acid A receptor, alpha subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
7	K03H1.8	K03H1.8	n/a	chrIII 9,945,970	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
8	F56H1.5	F56H1.5	n/a	chrI 5,757,572	F56H1.5 encodes a putative ATP/ADP-activated metallocarboxypeptidase that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; F56H1.5 is orthologous to murine AGTPBP-1/Nna1/pcd (upregulated in damaged mouse spinal cord and mutated in Purkinje cell degeneration) and human AGTPBP1 (OMIM:606830); murine AGTPBP-1 is genetically required for tubulin carboxypeptidase activity in vivo, and F56H1.5's nearest paralog EEED8.6 has biochemical traits consistent with tubulin carboxypeptidase activity; F56H1.5 and its mammalian AGTPBP1 orthologs, along with other proteins, comprise a M14D3 peptidase subfamily.
9	K07E8.5	K07E8.5	n/a	chrII 652,962	K07E8.5 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that K07E8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
10	fbxa-186	F47H4.6	n/a	chrV 17,337,347	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
11	F36G9.13	F36G9.13	n/a	chrV 15,984,973	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003125 (Protein of unknown function WSN)
12	C17B7.5	C17B7.5	n/a	chrV 3,336,321	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domains IPR002345 (Lipocalin), IPR006588 (Protein of unknown function PAW)
13	F49H6.12	F49H6.12	n/a	chrV 17,021,153	contains similarity to Phasianus colchicus Gag polyprotein (Fragment).; TR:Q9I9T0
14	T08G3.6	T08G3.6	n/a	chrV 16,446,543	contains similarity to Interpro domain IPR008975 ()
15	acr-18	F28F8.1	n/a	chrV 15,555,125	acr-18 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating fast action of acetylcholine at neuromuscular junctions and in the nervous system; ACR-18 falls into the 'DEG-3' class of nAChR subunits, apparently unique to nematodes, which includes DEG-3, DES-2, ACR-5, ACR-17, ACR-20, and ACR-23.
16	T08G3.7	T08G3.7	n/a	chrV 16,464,369	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
17	srh-252	T19C9.3	n/a	chrV 17,222,863	C. elegans SRH-252 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000215 (Protease inhibitor I4, serpin)
18	nhr-72	C17A2.8	n/a	chrII 3,849,882	C. elegans NHR-72 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	F26D11.4	F26D11.4	n/a	chrV 7,947,903
20	srh-25	C54D10.6	n/a	chrV 12,433,068	C. elegans SRH-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	fbxa-7	T20H9.1	n/a	chrIII 2,250,698	C. elegans FBXA-7 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
22	nhr-164	C41G6.5	n/a	chrV 15,234,803	C. elegans NHR-164 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
23	tax-4	ZC84.2	n/a	chrIII 9,183,509	tax-4 is orthologous to the human gene ROD PHOTORECEPTOR CGMP-GATED CHANNEL (CNGA1; OMIM:123825), which when mutated leads to disease.
24	K09F5.1	K09F5.1	n/a	chrX 7,740,721
25	T28A11.17	T28A11.17	n/a	chrV 3,264,867	T28A11.17 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T28A11.17 has no clear orthologs in other organisms.
26	sra-3	AH6.7	n/a	chrII 9,539,969	C. elegans SRA-3 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
27	srz-42	H12I19.1	n/a	chrIV 14,130,194	C. elegans SRZ-42 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
28	C09G1.2	C09G1.2	n/a	chrX 15,980,318	contains similarity to Saccharomyces cerevisiae Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1; SGD:YNL271C
29	Y51B9A.4	Y51B9A.4	n/a	chrII 9,408,334	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
30	C02F12.8	C02F12.8	n/a	chrX 3,691,690	contains similarity to Interpro domain IPR000694 (Proline-rich region)
31	srh-212	T22F3.6	n/a	chrV 3,596,155	C. elegans SRH-212 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001463 (Sodium:alanine symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
32	W04A4.5	W04A4.5	n/a	chrI 13,669,210	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
33	str-60	T06C12.1	n/a	chrV 15,898,679	C. elegans STR-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	C54C8.3	C54C8.3	n/a	chrI 12,447,783	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
35	srbc-59	R09E12.1	n/a	chrV 779,433	C. elegans SRBC-59 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
36	T07G12.4	T07G12.4	n/a	chrIV 10,537,682	contains similarity to Pfam domain PF00860 Permease family contains similarity to Interpro domain IPR006043 (Xanthine/uracil/vitamin C permease)
37	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
38	ZC482.4	ZC482.4	n/a	chrIII 12,766,680	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
39	C18E3.5	C18E3.5	n/a	chrI 4,198,275	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR001632 (G-protein, beta subunit), IPR015943 (WD40/YVTN repeat-like)
40	gcy-14	ZC412.2	n/a	chrV 14,865,514	gcy-14 encodes a predicted transmembrane guanylyl cyclase; the precise role of GCY-14 in C. elegans development and/or behavior is not yet known; however, by sequence similarity GCY-14 can be predicted to function in chemosensory signal transduction.
41	Y20C6A.3	Y20C6A.3	n/a	chrV 17,382,699	contains similarity to Saccharomyces cerevisiae Myo1 is a type II myosin, is localized to the actomyosin ring and is important for cytokinesis.; SGD:YHR023W
42	epac-1	T20G5.5	n/a	chrIII 10,191,417	C. elegans EPAC-1 protein; contains similarity to Pfam domains PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin) , PF00027 (Cyclic nucleotide-binding domain) (2), PF00617 (RasGEF domain) , PF00618 (Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif) contains similarity to Interpro domains IPR008937 (Ras guanine nucleotide exchange factor), IPR011051 (Cupin, RmlC-type), IPR001895 (Guanine-nucleotide dissociation stimulator CDC25), IPR011991 (Winged helix repressor DNA-binding), IPR000595 (Cyclic nucleotide-binding), IPR002373 (cAMP/cGMP-dependent protein kinase), IPR014710 (RmlC-like jelly roll fold), IPR000651 (Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal), IPR000591 (Pleckstrin/ G-protein, interacting region)
43	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
44	C25A1.12	C25A1.12	n/a	chrI 10,192,090	contains similarity to Pfam domain PF00561 alpha/beta hydrolase fold contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR003089 (Alpha/beta hydrolase), IPR002410 (Peptidase S33, prolyl aminopeptidase)
45	T19D2.3	T19D2.3	n/a	chrX 3,939,726
46	F27E5.5	F27E5.5	n/a	chrII 10,129,961	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
47	T23F4.1	T23F4.1	n/a	chrII 1,167,834	contains similarity to Pfam domain PF01738 Dienelactone hydrolase family contains similarity to Interpro domain IPR002925 (Dienelactone hydrolase)
48	C23H4.4	C23H4.4	n/a	chrX 12,231,444	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR000062 (Thymidylate kinase), IPR002018 (Carboxylesterase, type B)
49	F38A1.11	F38A1.11	n/a	chrIV 1,248,205	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
50	sri-53	ZC239.10	n/a	chrII 3,201,906	C. elegans SRI-53 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)