UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	col-158	D2023.7	4.0000000000000005e-71	chrV 11,830,378	C. elegans COL-158 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	col-2	W01B6.7	n/a	chrIV 10,084,918	col-2 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies); expression peaks during the molt that separates the L2 larval and dauer stages as the dauer cuticle is being formed, and mRNA is expressed at low levels in post-dauer L4 larvae and in adult animals.
4	T01C3.4	T01C3.4	n/a	chrV 14,994,531	contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
5	col-102	C18H7.3	n/a	chrIV 605,160	col-102 encodes a cuticle collagen.
6	grl-19	R02D3.6	n/a	chrIV 252,252	grl-19 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-19 is expressed in intestine; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
7	col-84	K12D12.3	0.000000001	chrII 11,869,021	C. elegans COL-84 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
8	nlp-28	B0213.3	n/a	chrV 3,988,091	C. elegans NLP-28 protein ; contains similarity to Ixodes scapularis Putative secreted salivary gland peptide.; TR:Q5Q982
9	F56H9.2	F56H9.2	n/a	chrV 12,637,872	contains similarity to Plasmodium falciparum Transport protein, putative.; TR:Q8IHR3
10	col-45	F53G12.7	n/a	chrI 116,588	col-45 encodes a cuticle collagen.
11	col-35	C15A11.1	n/a	chrI 7,386,359	col-35 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens; the amino- and carboxyl-terminal cysteine-rich regions of COL-35 are most closely related to those of COL-8, COL-19, and COL-39.
12	nlp-32	F30H5.2	n/a	chrIII 486,349	C. elegans NLP-32 protein; contains similarity to Interpro domain IPR002952 (Eggshell protein)
13	hsp-12.3	F38E11.1	n/a	chrIV 9,445,065	hsp-12.3 encodes a small heat-shock protein that forms heterotetramers with HSP-12.2 and has no chaperone-like activity; structurally, HSP-12.3 is mostly a beta-sheet; at least one HSP-12 (which may or may not be HSP-12.2) is ubiquitously expressed in L1 larvae, and later expressed in adult spermatids (and perhaps spermatocytes), and some adult vulval cells; hsp-12.3 is upregulated in daf-2 mutants, suggesting that hsp-12.3's expression may contribute to prolonged lifespan in dauer larvae.
14	F22B7.9	F22B7.9	n/a	chrIII 8,653,148
15	scl-11	F49E11.6	n/a	chrIV 13,051,732	C. elegans SCL-11 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
16	nlp-29	B0213.4	n/a	chrV 3,984,616	nlp-29 encodes a neuropeptide-like protein; nlp-29 appears to play a role in innate immunity, as its expression is strongly induced following bacterial and fungal infection; nlp-29 is expressed in the hypodermis and in the intestine; nlp-29 expression is regulated by TIR-1, an ortholog of SARM, a Toll-interleukin 1 receptor (TIR) domain protein, and by the RAB-1 GTPase and the product of R53.4, a mitochondrial ATP synthase subunit f homolog.
17	ZC395.5	ZC395.5	n/a	chrIII 5,268,152
18	C35C5.9	C35C5.9	n/a	chrX 11,536,770	contains similarity to Haemophilus influenzae Monofunctional biosynthetic peptidoglycan transglycosylases(EC 2.4.2.-) (Monofunctional TGase).; SW:MTGA_HAEIN
19	T20D4.11	T20D4.11	n/a	chrV 3,399,039	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
20	grl-17	C56A3.1	n/a	chrV 13,562,991	grl-17 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-17 is expressed in pharynx, rectal epithelium, amphid socket cells, larval arcade cells, and larval hypodermis; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
21	C30F12.3	C30F12.3	n/a	chrI 6,971,092
22	nlp-39	C54C8.9	n/a	chrI 12,461,774	C. elegans NLP-39 protein ;
23	clec-60	ZK666.6	n/a	chrII 10,480,905	clec-60 encodes a C-type lectin protein with no obvious non-nematode orthologs required for normal resistance to infection with Microbacterium nematophilum; clec-60 transcription is induced 6.6-fold by infection with M. nematophilum, making it one of the most strongly infection-responsive genes (second only to tts-1), while not being induced by other pathogens; CLEC-60 is expressed throughout the larval intestine, continuing adult expression primarily in the posterior intestinal cells int8 and int9; CLEC-60 contains an N-terminal von Willebrand factor type A domain and a C-terminal C-type lectin domain; CLEC-60 has no obvious function in mass RNAi assays, and is dispensable for viability.
24	C34C6.7	C34C6.7	n/a	chrII 8,707,892	contains similarity to Interpro domain IPR000533 (Tropomyosin)
25	C10G8.4	C10G8.4	n/a	chrV 5,312,109	C10G8.4 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; C10G8.4 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; C10G8.4 has no obvious function in mass RNAi assays.
26	cpi-1	K08B4.6	n/a	chrIV 6,093,107	cpi-1 encodes a homolog of cysteine protease inhibitors (cystatins); cpi-1 is at least superficially dispensable for viability and gross morphology.
27	clec-97	ZK39.6	n/a	chrI 11,153,502	C. elegans CLEC-97 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	F57F4.2	F57F4.2	n/a	chrV 6,388,125	contains similarity to Felis silvestris catus RPGR (Fragment).; TR:Q56PC0
29	cpr-2	F36D3.9	n/a	chrV 16,533,516	C. elegans CPR-2 protein; contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
30	F40G12.5	F40G12.5	n/a	chrV 14,269,931	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
31	F09F7.6	F09F7.6	n/a	chrIII 5,551,674
32	B0507.8	B0507.8	n/a	chrV 8,761,695	contains similarity to Schizosaccharomyces pombe Nucleoporin nup211 (Nuclear pore protein nup211).; SW:O74424
33	F11F1.6	F11F1.6	n/a	chrIII 13,403,684	contains similarity to Escherichia coli Shiga toxin 1 B subunit.; TR:Q8L167
34	T28A11.19	T28A11.19	n/a	chrV 3,269,156	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
35	ins-23	M04D8.3	n/a	chrIII 10,028,305	ins-23 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-23 is one of 38 insulin-like peptides in C. elegans, and is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral nerve cord neurons; as loss of INS-23 function via RNA-mediated interference does not results in any abnormalities, the precise role of INS-23 in C. elegans development is not yet clear.
36	W02D9.6	W02D9.6	n/a	chrI 12,560,492	contains similarity to Homo sapiens similar to KIAA1107 protein; ENSEMBL:ENSP00000176186
37	F47B8.8	F47B8.8	n/a	chrV 14,332,167	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domain IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal)
38	col-116	F17E9.1	n/a	chrIV 8,357,297	C. elegans COL-116 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
39	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
40	clec-98	ZK39.7	n/a	chrI 11,154,783	C. elegans CLEC-98 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
41	F43H9.4	F43H9.4	n/a	chrV 8,027,713	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
42	C23G10.11	C23G10.11	n/a	chrIII 6,215,297	contains similarity to Interpro domain IPR003059 (Colicin lysis protein)
43	grd-4	T01B10.1	n/a	chrX 8,501,684	grd-4 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-4 is weakly required for normal molting; GRD-4 is also required for normal adult alae formation, growth to full size, and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
44	acs-2	F28F8.2	n/a	chrV 15,568,615	C. elegans ACS-2 protein; contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
45	cut-1	C47G2.1	n/a	chrII 11,270,278	cut-1 encodes a component of cuticlin, an insoluble residue of the nematode cuticle required for alae formation and radial shrinking during dauer differentiation; expressed specifically in the cuticle of dauer larvae and is secreted by the seam cells.
46	C06G3.3	C06G3.3	n/a	chrIV 7,036,272
47	scl-2	F49E11.10	n/a	chrIV 13,058,350	C. elegans SCL-2 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
48	F07C4.6	F07C4.6	n/a	chrV 7,627,266	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
49	C18A11.1	C18A11.1	n/a	chrX 8,069,882
50	ugt-27	C10H11.5	n/a	chrI 4,725,415	C. elegans UGT-27 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)