UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	D1069.4	D1069.4	0	chrII 349,425	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	srh-22	C02E7.4	n/a	chrV 4,923,929	C. elegans SRH-22 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
4	F23B2.7	F23B2.7	n/a	chrIV 9,151,248	contains similarity to Homo sapiens similar to Cylicin I (Multiple-band polypeptide I); ENSEMBL:ENSP00000331556
5	Y54E2A.10	Y54E2A.10	n/a	chrII 14,791,729	contains similarity to Dictyostelium discoideum Protein-tyrosine phosphatase 3 (EC 3.1.3.48) (Protein-tyrosine-sphosphate phosphohydrolase 3).; SW:PTP3_DICDI
6	C35A11.1	C35A11.1	3e-72	chrV 5,406,834	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
7	F14B6.2	F14B6.2	n/a	chrI 12,220,319	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
8	ham-1	F53B2.6	n/a	chrIV 12,543,852	ham-1 encodes a novel protein with a winged helix DNA-binding motif; ham-1 is required for the asymmetric divisions of several neuroblasts in the developing embryo and may influence their spindle position; ham-1 mutations also exhibit HSN motor neuron migration defects; HAM-1 interacts with itself in a yeast two-hybrid screen and observations suggest that its multimerization is required for its proper localization; HAM-1 is cytoplasmic and is asymmetrically distributed to the posterior of the HSNPHB neuroblast.
9	egrh-1	C27C12.2	n/a	chrX 14,847,486	C27C12.2 is orthologous to the human gene BA436D10.3 (EARLY GROWTH RESPONSE 2 (KROX-20 (DROSOPHILA) HOMOLOG)) (EGR2; OMIM:129010), which when mutated leads to disease.
10	rgs-1	C05B5.7	n/a	chrIII 10,015,270	rgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons.
11	ttr-13	Y44A6B.4	n/a	chrV 20,631,647	C. elegans TTR-13 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
12	F40A3.7	F40A3.7	0.000003	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
13	elc-2	W03H1.2	n/a	chrX 1,777,746	elc-2 encodes a protein containing a Skp1 dimerisation domain that has homology to human transcription elongation factor B (SIII), polypeptide I (15kD, elonginsC).
14	E02H4.4	E02H4.4	n/a	chrX 14,259,690	contains similarity to Arabidopsis thaliana Uncharacterized protein At1g15830.1.; TR:Q3EDB7
15	B0554.3	B0554.3	n/a	chrV 434,275
16	srw-10	ZC482.6	n/a	chrIII 12,755,860	C. elegans SRW-10 protein ;
17	Y47D3B.3	Y47D3B.3	n/a	chrIII 11,400,137	contains similarity to Homo sapiens Low-density lipoprotein receptor-related protein 2 precursor; ENSEMBL:ENSP00000263816
18	npr-3	C10C6.2	n/a	chrIV 11,461,555	C10C6.2 encodes a G-protein-coupled receptor for the FMRFamide-related peptides (FaRPs) encoded by flp-15; C10C6.2 is primarily coupled to Gi/Go proteins, since C10C6.2 signalling is blocked by pertussis toxin; because of its link to Gi/Go proteins, C10C6.2 is expected to be inhibitory
19	sri-45	K07E8.9	n/a	chrII 660,949	C. elegans SRI-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	C15H9.4	C15H9.4	n/a	chrX 6,103,253	contains similarity to Danio rerio Novel protein similar to human cerebral protein 11 (HUCEP11).; TR:Q1MTK0
21	F16G10.13	F16G10.13	n/a	chrII 2,395,441	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
22	mab-5	C08C3.3	n/a	chrIII 7,780,108	mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog.
23	C30G4.6	C30G4.6	n/a	chrX 17,077,020	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
24	C15B12.3	C15B12.3	n/a	chrX 6,467,380
25	M05B5.6	M05B5.6	n/a	chrI 7,184,379	contains similarity to Homo sapiens Transient receptor potential cation channel subfamily A member 1; ENSEMBL:ENSP00000262209
26	T11F9.14	T11F9.14	n/a	chrV 11,480,742	contains similarity to Oryctolagus cuniculus Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).; SW:TRIF_RABIT
27	F55D12.1	F55D12.1	n/a	chrI 7,884,957	contains similarity to Brachydanio rerio Hypothetical protein.; TR:Q803L4
28	R04E5.7	R04E5.7	n/a	chrX 8,797,318
29	srx-136	F09F3.12	n/a	chrV 13,858,174	C. elegans SRX-136 protein ;
30	T05H10.8	T05H10.8	n/a	chrII 8,060,196	contains similarity to Streptococcus pneumoniae Cell division regulator, negative regulator of FtsZ ringsformation.; TR:Q8DQE5
31	srw-140	C03A7.3	0.0000000000001	chrV 5,166,467	C. elegans SRW-140 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
32	F14H8.4	F14H8.4	n/a	chrV 15,024,402	contains similarity to Clostridium acetobutylicum Protein containing a domain related to multimeric flavodoxin WrbAsfamily.; TR:Q97H25
33	nhr-182	F41B5.9	n/a	chrV 2,258,611	C. elegans NHR-182 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
34	str-87	F59E11.16	n/a	chrV 8,987,304	C. elegans STR-87 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	lgc-55	Y113G7A.5	n/a	chrV 20,025,213	C. elegans LGC-55 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002289 (Gamma-aminobutyric-acid A receptor, beta subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR013032 (EGF-like region, conserved site), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
36	srh-74	C45B11.4	n/a	chrV 11,047,962	C. elegans SRH-74 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	T03G11.3	T03G11.3	n/a	chrX 5,175,968	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
38	clec-10	C03H5.1	n/a	chrII 403,400	C. elegans CLEC-10 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
39	glc-3	ZC317.3	n/a	chrV 5,451,485	The glc-3 gene encodes a fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit.
40	egl-10	F28C1.2	n/a	chrV 12,459,067	egl-10 encodes an RGS protein, expressed in neurons, that affects egg laying and negatively regulates GOA-1 (Galpha[o]) signalling; it requires the Gbeta(5) ortholog GPB-2 for this activity, and genetically interacts with the egl-30 and goa-1 signaling pathways.
41	F11G11.4	F11G11.4	n/a	chrII 4,861,326
42	sre-14	C42C1.1	n/a	chrIV 12,260,640	C. elegans SRE-14 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
43	nhr-167	C49F5.4	n/a	chrX 11,981,020	C. elegans NHR-167 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
44	Y106G6H.4	Y106G6H.4	n/a	chrI 10,437,301	contains similarity to Interpro domain IPR006578 (MADF)
45	ZK384.3	ZK384.3	n/a	chrV 18,730,891	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001412 (Aminoacyl-tRNA synthetase, class I, conserved site), IPR001461 (Peptidase A1)
46	ssu-1	Y113G7A.11	n/a	chrV 20,126,167	ssu-1 encodes, by alternative splicing, two isoforms of a cytosolic alcohol sulfotransferase that interacts in the ASJ amphid neurons with the stomatins UNC-1 and UNC-24; the longer SSU-1 isoform is required for normal anesthetic sensitivity and unc-1 phenotypes; ssu-1(fc73) suppresses the anesthetic sensitivity and uncoordinated phenotypes of unc-1 and unc-24 mutants; ssu-1(fc73), along with daf-12, suppresses the synthetic constitutive dauer-formation phenotype of fc83;unc-24(e138) mutants; ssu-1 suppression is rescued by transgenic expression of SSU-1 in the ASJ neurons alone, implying that sulfation is required for an endocrine function; SSU-1 protein sulfates 4-nitrophenol and 2-naphthol substrates, and bisphenol A, but not monoamines or hydroxysteroids; SSU-1 is cytosolic, but its activity is not detectable in cytosolic extracts; ssu-1 is strongly expressed in embryos, growing larvae, and dauer larvae; ssu-1 expression is increased in daf-2; by homology with other sulfotransferases, SSU-1 may link sulfates to the alcohol group of small molecules as part of detoxification or signal transduction.
47	ZK287.4	ZK287.4	n/a	chrV 9,682,882	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR000694 (Proline-rich region), IPR006150 (Cysteine-rich repeat)
48	str-4	C50B6.10	n/a	chrV 13,338,836	C. elegans STR-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	F45E1.2	F45E1.2	n/a	chrX 8,003,850
50	F45E6.3	F45E6.3	n/a	chrX 12,488,021	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)