UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	D1046.4	D1046.4	0	chrIV 8,935,680	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
2	ZK593.8	ZK593.8	n/a	chrIV 10,938,663	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) , PF02661 (Fic protein family) contains similarity to Interpro domains IPR003812 (Filamentation induced by cAMP protein Fic), IPR011990 (Tetratricopeptide-like helical), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	acl-2	T06E8.1	n/a	chrV 10,029,692	T06E8.1 is orthologous to the human gene 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 2 (LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE, BETA) (AGPAT2; OMIM:603100), which when mutated leads to disease; T06E8.1 protein is predicted to be mitochondrial.
5	K11G9.3	K11G9.3	n/a	chrV 6,670,893	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
6	btb-19	F57C2.2	n/a	chrII 14,521,504	C. elegans BTB-19 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
7	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
8	srw-16	T10H4.5	n/a	chrV 15,274,096	C. elegans SRW-16 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor)
9	T22H6.1	T22H6.1	n/a	chrX 12,768,557	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
10	T27A3.6	T27A3.6	n/a	chrI 6,106,790	T27A3.6 is orthologous to the human gene MOLYBDENUM COFACTOR BIOSYSTHESIS PROTEIN E (MOCS2; OMIM:603708), which when mutated leads to disease.
11	B0205.9	B0205.9	n/a	chrI 10,722,143	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
12	F14H3.4	F14H3.4	n/a	chrV 16,054,667	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
13	E02H4.2	E02H4.2	n/a	chrX 14,279,950	contains similarity to Homo sapiens Type-1 protein phosphatase skeletal muscle glycogen targeting subunit; ENSEMBL:ENSP00000284601
14	C18E3.5	C18E3.5	n/a	chrI 4,198,275	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR001632 (G-protein, beta subunit), IPR015943 (WD40/YVTN repeat-like)
15	F56H1.5	F56H1.5	n/a	chrI 5,757,572	F56H1.5 encodes a putative ATP/ADP-activated metallocarboxypeptidase that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; F56H1.5 is orthologous to murine AGTPBP-1/Nna1/pcd (upregulated in damaged mouse spinal cord and mutated in Purkinje cell degeneration) and human AGTPBP1 (OMIM:606830); murine AGTPBP-1 is genetically required for tubulin carboxypeptidase activity in vivo, and F56H1.5's nearest paralog EEED8.6 has biochemical traits consistent with tubulin carboxypeptidase activity; F56H1.5 and its mammalian AGTPBP1 orthologs, along with other proteins, comprise a M14D3 peptidase subfamily.
16	fbxb-13	C08F1.3	n/a	chrII 1,789,688	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
17	T28F2.1	T28F2.1	n/a	chrI 3,640,560	contains similarity to Pfam domain PF01531 Glycosyl transferase family 11 contains similarity to Interpro domain IPR002516 (Glycosyl transferase, family 11)
18	str-260	T24A6.6	n/a	chrV 3,528,795	C. elegans STR-260 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	C53C7.3	C53C7.3	n/a	chrX 13,049,643	contains similarity to Triticum aestivum Alpha/beta-gliadin A-V precursor (Prolamin).; SW:GDA5_WHEAT
20	dct-12	Y57A10C.7	n/a	chrII 12,431,464	C. elegans DCT-12 protein ;
21	rfc-1	C54G10.2	n/a	chrV 14,644,310	C. elegans RFC-1 protein; contains similarity to Pfam domains PF00004 (ATPase family associated with various cellular activities (AAA)) , PF08519 (Replication factor RFC1 C terminal domain) contains similarity to Interpro domains IPR013725 (DNA replication factor RFC1, C-terminal), IPR003959 (AAA ATPase, core), IPR008921 (DNA polymerase III clamp loader subunit, C-terminal), IPR012178 (DNA replication factor C, large subunit), IPR003593 (AAA+ ATPase, core), IPR001984 (Peptidase S16, Lon protease)
22	M04C9.2	M04C9.2	n/a	chrI 9,347,132	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
23	K12B6.6	K12B6.6	n/a	chrV 6,294,114
24	xpa-1	K07G5.2	n/a	chrI 7,160,236	xpa-1 encodes an ortholog of human XPA, the xeroderma pigmentosum complementation group A protein (OMIM:278700, mutations are associated with sensitivity to ultraviolet light and carcinomata at an early age); by homology, XPA-1 is predicted to function as a DNA-binding protein that is required for nucleotide excision repair of damaged DNA; in C. elegans, loss of xpa-1 activity via mutation or RNA-mediated interference (RNAi) results in increased sensitivity to UV irradiation at all stages of development; xpa-1 mRNA is detected in eggs and mixed stage populations.
25	clec-188	M199.3	n/a	chrIV 15,117,866	C. elegans CLEC-188 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
26	M04B2.2	M04B2.2	n/a	chrIV 11,529,284	contains similarity to Pfam domains PF01170 (Putative RNA methylase family UPF0020) , PF02926 (THUMP domain) contains similarity to Interpro domains IPR004114 (THUMP), IPR001091 (Site-specific DNA-methyltransferase (cytosine-N4-specific)), IPR000241 (Putative RNA methylase)
27	B0454.5	B0454.5	n/a	chrII 3,039,835	contains similarity to Homo sapiens 21 kDa protein; VG:OTTHUMP00000165983
28	ZK945.4	ZK945.4	n/a	chrII 10,104,330	contains similarity to Pfam domains PF00621 (RhoGEF domain) , PF00169 (PH domain) contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR015721 (Rho GTP exchange factor)
29	B0547.2	B0547.2	n/a	chrIV 5,646,017
30	srxa-4	F18E3.1	n/a	chrV 7,421,068	C. elegans SRXA-4 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
31	srv-22	H04M03.9	n/a	chrIV 5,879,196	C. elegans SRV-22 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
32	M18.6	M18.6	n/a	chrIV 12,122,042	contains similarity to Interpro domain IPR003111 (Peptidase S16, lon N-terminal)
33	clec-212	F19F10.7	n/a	chrV 7,566,626	C. elegans CLEC-212 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
34	srh-46	T03F7.3	n/a	chrV 11,302,223	C. elegans SRH-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	Y20C6A.3	Y20C6A.3	n/a	chrV 17,382,699	contains similarity to Saccharomyces cerevisiae Myo1 is a type II myosin, is localized to the actomyosin ring and is important for cytokinesis.; SGD:YHR023W
36	C48B4.8	C48B4.8	n/a	chrIII 9,560,470	contains similarity to Bacillus subtilis Hypothetical protein ywcE precursor.; SW:YWCE_BACSU
37	C45G9.2	C45G9.2	n/a	chrIII 5,069,704	contains similarity to Pfam domain PF01207 Dihydrouridine synthase (Dus) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR003733 (Thiamine monophosphate synthase), IPR001269 (Dihydrouridine synthase, DuS)
38	F13E9.1	F13E9.1	n/a	chrIV 10,868,951	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (4), PF00787 (PX domain) contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR001683 (Phox-like), IPR003591 (Leucine-rich repeat, typical subtype)
39	srw-134	T05B4.7	n/a	chrV 4,111,591	C. elegans SRW-134 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
40	T09E11.8	T09E11.8	n/a	chrI 12,351,698	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
41	F54B11.7	F54B11.7	n/a	chrX 13,600,836	contains similarity to Neurospora crassa GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).; SW:GCH1_NEUCR
42	sre-7	K02E11.2	n/a	chrV 14,245,132	C. elegans SRE-7 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
43	T19D2.3	T19D2.3	n/a	chrX 3,939,726
44	cyp-35B3	K07C6.2	n/a	chrV 3,946,183	C. elegans CYP-35B3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
45	C04F12.1	C04F12.1	n/a	chrI 9,676,100	contains similarity to Pfam domain PF02171 Piwi domain contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
46	srbc-59	R09E12.1	n/a	chrV 779,433	C. elegans SRBC-59 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	str-108	F10A3.13	n/a	chrV 16,166,795	C. elegans STR-108 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	srw-77	W06G6.8	n/a	chrV 16,642,725	C. elegans SRW-77 protein ;
49	acc-3	F55D10.5	n/a	chrX 4,725,216	C. elegans ACC-3 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR001390 (Gamma-aminobutyric-acid A receptor, alpha subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
50	pme-2	E02H1.4	n/a	chrII 9,594,003	pme-2 encodes a poly(ADP-ribose) polymerase (PARP) orthologous to human PARP2 (OMIM:607725); PME-2 has a predicted C-terminal catalytic domain; PME-2 has PARP activity in vitro, which is blocked by mammalian PARP inhibitors; since these inhibitors also cause embryonic lethality in worms exposed to ionizing radiation, PME-1 is likely to be required in vivo for repairing broken DNA.