UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	D1025.2	D1025.2	5e-72	chrX 14,514,552	contains similarity to Pfam domain PF01597 Glycine cleavage H-protein contains similarity to Interpro domains IPR017453 (Glycine cleavage H-protein, subgroup), IPR011053 (Single hybrid motif), IPR002930 (Glycine cleavage H-protein)
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	W04G3.5	W04G3.5	n/a	chrX 11,074,823	contains similarity to Pfam domain PF00156 Phosphoribosyl transferase domain contains similarity to Interpro domains IPR005946 (Phosphoribosyl pyrophosphokinase), IPR000836 (Phosphoribosyltransferase)
4	gsto-1	C29E4.7	n/a	chrIII 7,946,235	gsto-1 encodes an experimentally verified thiol oxidoreductase and dehydroascorbate reductase, required for normal stress resistance; formally, GSTO-1 is an omega-class glutathione transferase (GST; EC 2.5.1.18), but it has little activity in vitro on classic GST substrates; GSTO-1 is expressed in postembryonic intestine; gsto-1(RNAi) induces hypersensitivity to heat-, arsenite-, juglone-, paraquat-, or cumene hydroperoxide-induced stresses, whereas overexpression of GSTO-1 enhances resistance to them; gsto-1 transcription is upregulated by stress; ELT-2 may directly activate gsto-1 transcription in developing gut via a 300-nucleotide sequence upstream of gsto-1's ATG start site.
5	M28.5	M28.5	n/a	chrII 10,658,303	contains similarity to Pfam domain PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family contains similarity to Interpro domains IPR004038 (Ribosomal protein L7Ae/L30e/S12e/Gadd45), IPR000948 (Ribosomal protein HS6), IPR004037 (Ribosomal protein L7Ae), IPR002415 (High mobility group-like nuclear protein)
6	eft-1	ZK328.2	n/a	chrIII 6,011,147	eft-1 encodes an elongation factor 2 (EF-2)-like protein; by homology, EFT-1 is predicted to function as a GTPase required for the elongation step of protein synthesis; loss of eft-1 activity via large-scale RNAi indicates that eft-1 is an essential gene required for embryonic development, reproduction, and the overall health of the animal; eft-1 mRNA is detectable at all stages of C. elegans development.
7	aqp-11	ZK525.2	n/a	chrIII 13,673,891	aqp-11 encodes a putative aquaporin with no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-9 and AQP-10; AQP-11 is orthologous to Drosophila CG12251 and human AQP11 (OMIM:609914), AQP12A (OMIM:609789), and AQP12B.
8	cyp-35C1	C06B3.3	n/a	chrV 13,897,551	C. elegans CYP-35C1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
9	clec-56	F08H9.7	n/a	chrV 14,475,609	C. elegans CLEC-56 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
10	cct-1	T05C12.7	n/a	chrII 8,186,346	cct-1 encodes a putative alpha subunit of the eukaryotic cytosolic ('T complex') chaperonin, orthologous to human TCP1 (OMIM:186980), and required for normal pronuclear-centrosome rotation, positioning of the mitotic spindle, meiosis, and distal tip cell migration; CCT-1 is also required to repress SKN-1-dependent transcription of gst-4, and for fertility and viability; CCT-1 is expressed in larval and adult pharynx, intestine, body wall muscle, and neurons, as well as adult rectal epithelium; cct-1 mRNA is enriched in cultured touch receptor neurons.
11	dct-18	F58G1.4	n/a	chrII 12,932,607	C. elegans DCT-18 protein; contains similarity to Interpro domain IPR000886 (Endoplasmic reticulum, targeting sequence)
12	phb-2	T24H7.1	n/a	chrII 6,252,083	phb-2 encodes one of two subunits of the mitochondrial prohibitin complex; loss of phb-2 activity via RNAi indicates that phb-2 function is required for mitochondrial biogenesis and maintenance and for embryonic, germline, and somatic gonad development.
13	C18E9.6	C18E9.6	n/a	chrII 8,972,695	contains similarity to Pfam domain PF01459 Eukaryotic porin contains similarity to Interpro domain IPR001925 (Porin, eukaryotic type)
14	F57B9.3	F57B9.3	n/a	chrIII 6,940,892	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
15	W09D10.3	W09D10.3	n/a	chrIII 10,708,021	contains similarity to Pfam domain PF00542 Ribosomal protein L7/L12 C-terminal domain contains similarity to Interpro domains IPR013823 (Ribosomal protein L7/L12, C-terminal), IPR014719 (Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like), IPR008932 (Ribosomal protein L7/L12, oligomerisation)
16	F59B8.2	F59B8.2	n/a	chrIV 9,439,991	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004790 (Isocitrate dehydrogenase NADP-dependent, eukaryotic), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
17	F11C1.3	F11C1.3	n/a	chrX 12,983,754	contains similarity to Pfam domain PF01130 CD36 family contains similarity to Interpro domain IPR002159 (CD36 antigen)
18	F14B4.3	F14B4.3	n/a	chrI 9,283,761	contains similarity to Pfam domains PF06883 (RNA polymerase I, Rpa2 specific domain) , PF04561 (RNA polymerase Rpb2, domain 2) , PF04567 (RNA polymerase Rpb2, domain 5) , PF04565 (RNA polymerase Rpb2, domain 3) , PF00562 (RNA polymerase Rpb2, domain 6) , PF04560 (RNA polymerase Rpb2, domain 7) , PF04563 (RNA polymerase beta subunit) contains similarity to Interpro domains IPR007120 (DNA-directed RNA polymerase, subunit 2, domain 6), IPR007641 (RNA polymerase Rpb2, domain 7), IPR007644 (RNA polymerase, beta subunit, protrusion), IPR009674 (RNA polymerase I, Rpa2 specific), IPR015712 (DNA-directed RNA polymerase, subunit 2), IPR007645 (RNA polymerase Rpb2, domain 3), IPR007642 (RNA polymerase Rpb2, domain 2), IPR007647 (RNA polymerase Rpb2, domain 5), IPR007121 (RNA polymerase, beta subunit, conserved site)
19	C18E9.5	C18E9.5	n/a	chrII 8,970,895	contains similarity to Turkey herpesvirus LORF11.; TR:Q9IBS2
20	nol-5	W01B11.3	n/a	chrI 3,268,107	C. elegans NOL-5 protein; contains similarity to Pfam domains PF01798 (Putative snoRNA binding domain) , PF08060 (NOSIC (NUC001) domain) , PF08156 (NOP5NT (NUC127) domain) contains similarity to Interpro domains IPR012974 (NOP5, N-terminal), IPR005819 (Histone H5), IPR002687 (Pre-mRNA processing ribonucleoprotein, binding region), IPR012976 (NOSIC)
21	F53E10.6	F53E10.6	n/a	chrV 2,602,650	contains similarity to Pfam domain PF07890 Rrp15p contains similarity to Interpro domain IPR012459 (Protein of unknown function DUF1665)
22	pfd-3	T06G6.9	n/a	chrI 12,729,010	pfd-3 encodes a putative prefoldin, orthologous to human VBP1 (OMIM:300133), that is required for normal alpha-tubulin synthesis, microtubule growth, mitotic spindle formation and positioning, early embryonic cell division, and embryonic and larval viability; PFD-3 is expressed cytoplasmically in most, if not all, tissues.
23	dap-3	C14A4.2	n/a	chrII 10,581,748	dap-3 is an ortholog of mammalian death-associated protein 3 (DAP3), a mitochondrial ribosomal protein that promotes apoptosis.
24	C29F7.3	C29F7.3	n/a	chrX 13,419,306	contains similarity to Pfam domain PF00406 Adenylate kinase contains similarity to Interpro domains IPR000764 (Uridine kinase), IPR000850 (Adenylate kinase), IPR006266 (UMP-CMP kinase), IPR011769 (Adenylate/cytidine kinase, N-terminal)
25	T23B12.2	T23B12.2	n/a	chrV 8,468,082	contains similarity to Pfam domain PF00573 Ribosomal protein L4/L1 family contains similarity to Interpro domains IPR013005 (Ribosomal protein L4/L1e, bacterial-type), IPR002136 (Ribosomal protein L4/L1e)
26	K12H4.3	K12H4.3	n/a	chrIII 8,046,749	contains similarity to Pfam domain PF04427 Brix domain contains similarity to Interpro domain IPR007109 (Brix)
27	dnj-11	F38A5.13	n/a	chrIV 6,587,011	This gene encodes a protein containing a DnaJ ('J') domain.
28	F36A2.3	F36A2.3	n/a	chrI 8,800,214	contains similarity to Pfam domain PF02615 Malate/L-lactate dehydrogenase contains similarity to Interpro domain IPR003767 (Malate/L-lactate dehydrogenase)
29	F14D7.6	F14D7.6	n/a	chrV 14,303,902	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
30	gst-13	T26C5.1	n/a	chrII 9,231,840	C. elegans GST-13 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
31	W07E6.2	W07E6.2	n/a	chrII 482,556	W07E6.2 encodes an ortholog of S. cerevisiae RSA4 that may suppress tumorous growth in the germline; like PRO-1, -2, and -3, W07E6.2 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline.
32	clec-17	E03H4.10	n/a	chrI 12,430,738	C. elegans CLEC-17 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	nol-10	F32E10.1	n/a	chrIV 7,582,143	C. elegans NOL-10 protein; contains similarity to Pfam domain PF08159 NUC153 domain contains similarity to Interpro domains IPR012580 (NUC153), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
34	R06C1.4	R06C1.4	n/a	chrI 11,931,232	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1), IPR002343 (Paraneoplastic encephalomyelitis antigen)
35	R07H5.8	R07H5.8	n/a	chrIV 11,210,138	contains similarity to Pfam domain PF00294 pfkB family carbohydrate kinase contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR002139 (Ribokinase), IPR001805 (Adenosine kinase), IPR002173 (Carbohydrate/puine kinase, PfkB, conserved site)
36	ZK1127.5	ZK1127.5	n/a	chrII 7,051,269	contains similarity to Pfam domains PF01137 (RNA 3'-terminal phosphate cyclase) , PF05189 (RNA 3'-terminal phosphate cyclase (RTC), insert domain) contains similarity to Interpro domains IPR016443 (RNA 3'-terminal phosphate cyclase-like, eukaryotic), IPR013796 (RNA 3'-terminal phosphate cyclase, insert region), IPR000228 (RNA 3'-terminal phosphate cyclase), IPR013792 (RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)
37	E04A4.5	E04A4.5	n/a	chrIV 4,744,928	contains similarity to Pfam domain PF02466 Tim17/Tim22/Tim23 family contains similarity to Interpro domains IPR005678 (Mitochondrial import inner membrane translocase, subunit Tim17), IPR003397 (Mitochondrial import inner membrane translocase, subunit Tim17/22)
38	K07C5.4	K07C5.4	n/a	chrV 10,351,696	contains similarity to Pfam domains PF01798 (Putative snoRNA binding domain) , PF08060 (NOSIC (NUC001) domain) , PF08156 (NOP5NT (NUC127) domain) contains similarity to Interpro domains IPR012974 (NOP5, N-terminal), IPR005819 (Histone H5), IPR002687 (Pre-mRNA processing ribonucleoprotein, binding region), IPR012976 (NOSIC)
39	H06H21.3	H06H21.3	n/a	chrIV 4,811,443	contains similarity to Pfam domain PF01176 Translation initiation factor 1A / IF-1 contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR006196 (S1, IF1 type), IPR001253 (Eukaryotic initiation factor 1A (eIF-1A))
40	F32A5.3	F32A5.3	n/a	chrII 7,234,327	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
41	lpd-6	K09H9.6	n/a	chrI 3,146,111	lpd-6 encodes a predicted rRNA-binding protein that is orthologous to Drosophila Peter Pan and the Saccharomyces cerevisiae SSF1 and SSF2 proteins that are required for ribosomal large subunit maturation; loss of lpd-6 activity via RNAi indicates that, in C. elegans, LPD-6 is required for fat storage and for larval growth and development; based upon its similarity to yeast SSF1 and SSF2, LPD-6 is predicted to be a nucleolar protein.
42	ruvb-1	C27H6.2	n/a	chrV 9,979,753	C. elegans RUVB-1 protein; contains similarity to Pfam domain PF06068 TIP49 C-terminus contains similarity to Interpro domains IPR010339 (TIP49, C-terminal), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal)
43	F20G2.1	F20G2.1	n/a	chrV 13,752,929	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
44	nhx-2	B0495.4	n/a	chrII 7,692,262	nhx-2 encodes a sodium/proton exchanger expressed in the apical membranes of intestinal cells; NHX-2 is required for normally high growth rates, and for propagation or maintenance of the germline, NHX-2 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of extracellular sodium for an intracellular proton.
45	T25D3.2	T25D3.2	n/a	chrII 155,462	contains similarity to Mus musculus 39S ribosomal protein L28, mitochondrial precursor (L28mt) (MRP-L28).; SW:Q9D1B9
46	C18D11.3	C18D11.3	n/a	chrIII 11,823,825	contains similarity to Homo sapiens Transcription factor MLL UPN95022; TR:Q86YN8
47	F25B4.6	F25B4.6	n/a	chrV 5,683,638	F25B4.6 is orthologous to the human gene 3-HYDROXY-3-METHYLGLUTARYL COA SYNTHASE (HMGCS2; OMIM:600234), which when mutated leads to disease.
48	eif-3.K	T16G1.11	n/a	chrV 12,954,593	The protein product of this gene was predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS72 release of WormBase, i.e., in wormpep77).
49	F23C8.5	F23C8.5	n/a	chrI 2,419,472	The F23C8.5 gene encodes an ortholog of the human gene ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT (ETFB), which when mutated leads to glutaricaciduria type IIB (OMIM:130410).
50	K06A4.5	K06A4.5	n/a	chrV 9,506,309	contains similarity to Pfam domain PF06052 3-hydroxyanthranilic acid dioxygenase contains similarity to Interpro domains IPR011051 (Cupin, RmlC-type), IPR016700 (3-hydroxyanthranilate 3, 4-dioxygenase, metazoan), IPR010329 (3-hydroxyanthranilic acid dioxygenase)