UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sul-2	D1014.1	0	chrV 8,158,775	sul-2 is orthologous to the human gene ARYLSULFATASE A (ARSA; OMIM:250100), which when mutated leads to metachromatic leukodystrophy.
2	F43G9.5	F43G9.5	n/a	chrI 8,615,863	F43G9.5 encodes a NUDIX hydrolase that that inhibits DHC-1 in vivo, and is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; F43G9.5(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that F43G9.5 negatively regulates dynein; while loss of F43G9.5 function has no obvious effect on lifespan, dauer formation, or fat storage, F43G9.5 is required for embryonic development, fertility, and general health in mass RNAi assays.
3	flp-13	F33D4.3	n/a	chrIV 7,697,747	C. elegans FLP-13 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
4	ida-1	B0244.2	n/a	chrIII 5,760,627	ida-1 encodes a protein tyrosine phosphatase-like receptor, orthologous to the mammalian type I diabetes autoantigens IA-2 and phogrin that are expressed in dense core vesicles of neuroendocrine tissue and involved in regulated protein secretion; in C. elegans, IDA-1 appears to be required for regulating presynaptic neurotransmission and in particular, for the neuropeptidergic control of egg-laying; ida-1 interacts genetically with unc-31 and unc-64, which encode proteins required for dense core vesicle fusion and exocytosis; ida-1 expression is detected in a subset of neurons in the anterior nerve ring, the ventral nerve cord, the tail, and the vulva, including the VC vulval motoneurons and the HSN egg-laying neurons; ida-1 is also detected in the vulval uv1 cells, non-neuronal cells that contain neurosecretory-like vesicles.
5	tsp-1	C02F5.8	n/a	chrIII 8,238,638	C. elegans TSP-1 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin), IPR013305 (ABC transporter, ABCB2), IPR003091 (Voltage-dependent potassium channel)
6	C15C7.4	C15C7.4	n/a	chrX 3,146,822
7	C54C6.5	C54C6.5	n/a	chrIII 3,549,652	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_4440.; TR:Q98QC2
8	R11D1.3	R11D1.3	n/a	chrV 12,711,700	contains similarity to Proteus mirabilis Hypothetical protein (Fragment).; TR:O86985
9	ins-30	ZC334.2	n/a	chrI 14,035,617	ins-30 encodes an insulin-like peptide.
10	C47D2.1	C47D2.1	n/a	chrX 8,215,243
11	F21F3.1	F21F3.1	n/a	chrI 4,909,304	contains similarity to Pfam domain PF01436 NHL repeat contains similarity to Interpro domains IPR000720 (Peptidyl-glycine alpha-amidating monooxygenase), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013017 (NHL repeat, subgroup), IPR015943 (WD40/YVTN repeat-like), IPR001258 (NHL repeat)
12	drn-1	C54A12.4	n/a	chrII 5,271,026	C. elegans DRN-1 protein; contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
13	K12B6.4	K12B6.4	n/a	chrV 6,280,741
14	hen-1	C36B7.7	n/a	chrX 7,116,551	hen-1 encodes a secreted protein that contains a low-density lipoprotein (LDL) receptor motif A; HEN-1 activity is required for integration of sensory stimuli and behavioral plasticity; a hen-1::GFP reporter is expressed in pharyngeal muscles, the vulva, and weakly in a subset of neurons; antibodies to HEN-1 protein detect expression exclusively in the AIY and ASE neurons, where HEN-1 appears to localize to cell bodies and in a punctate pattern in nerve ring axons at sites of synapse formation; HEN-1 expression in AIY appears to be under the control of the TTX-3 LIM domain transcription factor.
15	ttr-28	R90.3	n/a	chrV 12,904,670	C. elegans TTR-28 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
16	cyp-14A5	F08F3.7	n/a	chrV 5,422,142	cyp-14A5 encodes a member of the cytochrome P450 family.
17	sol-1	C15A11.3	n/a	chrI 7,392,485	C. elegans SOL-1 protein; contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
18	C49G7.10	C49G7.10	n/a	chrV 4,041,191	contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
19	cal-4	T07G12.1	n/a	chrIV 10,528,321	cal-4 encodes one of five predicted C. elegans calcium-binding calmodulin homologs (the others being CAL-1, CAL-2, CAL-3 and CMD-1); as loss of cal-4 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CAL-4 in C. elegans development and/or behavior is not yet known.
20	C55A6.6	C55A6.6	n/a	chrV 11,514,222	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
21	C17H12.10	C17H12.10	n/a	chrIV 6,808,208
22	C01G10.4	C01G10.4	n/a	chrV 15,089,864	contains similarity to Staphylococcus aureus Staphylococcal secretory antigen ssaA2 precursor.; SW:Q5HDQ9
23	F08G2.5	F08G2.5	n/a	chrII 13,833,272	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
24	C07A12.2	C07A12.2	n/a	chrX 4,545,119
25	nlp-11	ZK1320.10	n/a	chrII 9,690,787	C. elegans NLP-11 protein ;
26	dod-6	T20G5.7	n/a	chrIII 10,197,925	C. elegans DOD-6 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
27	tig-2	F39G3.8	n/a	chrV 4,728,435	The tig-2 gene, like dbl-1, daf-7, and unc-129, encodes a TGF-beta-like protein.
28	F07G11.7	F07G11.7	n/a	chrV 7,303,485	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
29	scl-3	F49E11.11	n/a	chrIV 13,060,112	C. elegans SCL-3 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
30	C49G7.6	C49G7.6	n/a	chrV 4,041,399
31	fipr-22	C37A5.2	n/a	chrI 14,155,893	C. elegans FIPR-22 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
32	F14D7.8	F14D7.8	n/a	chrV 14,312,353	contains similarity to Staphylococcus epidermidis Conserved hypothetical protein.; TR:Q8CSE5
33	R06F6.7	R06F6.7	n/a	chrII 10,811,543	contains similarity to Saccharomyces cerevisiae FLO5- and FLO8-determined flocculation are considerably less sensitive to mannose than FLO1-determined flocculation.; SGD:YHR211W
34	K09D9.1	K09D9.1	n/a	chrV 4,025,632
35	Y37H2C.1	Y37H2C.1	n/a	chrV 18,275,256	contains similarity to Homo sapiens SIDT1 protein; ENSEMBL:ENSP00000377416
36	F52E1.8	F52E1.8	n/a	chrV 8,393,368	contains similarity to Pfam domains PF00300 (Phosphoglycerate mutase family) , PF00328 (Histidine acid phosphatase) contains similarity to Interpro domains IPR000560 (Histidine acid phosphatase), IPR013078 (Phosphoglycerate mutase)
37	F41G3.10	F41G3.10	n/a	chrII 6,749,016	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
38	mec-9	C50H2.3	n/a	chrV 9,911,331	mec-9 encodes a predicted extracellular protein containing six EGF-like repeats,five Kunitz-type protease inhibitor domains, and a glutamic acid-rich region possibly involved in protein-protein interactions; mec-9 encodes two proteins, only one of which, MEC-9L, appears to be required for normal mechanosensory response to gentle touch and proper functioning of the touch receptor neurons; mec-9 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-9L is expressed and secreted by the touch receptor neurons.
39	F47B10.8	F47B10.8	n/a	chrX 10,905,841	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
40	xbx-3	M04D8.6	n/a	chrIII 10,036,315	C. elegans XBX-3 protein ;
41	T21C9.11	T21C9.11	n/a	chrV 10,594,469	contains similarity to Homo sapiens Popeye domain containing protein 3; ENSEMBL:ENSP00000254765
42	F41D3.8	F41D3.8	n/a	chrI 12,267,803	contains similarity to Pfam domain PF01697 (Domain of unknown function)
43	flp-5	C03G5.7	n/a	chrX 8,529,581	flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms; expressed in the sensory neurons ASE and PVM.
44	zig-5	Y48A6A.1	n/a	chrIII 10,952,247	zig-5 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-5::gfp reporter fusion is expressed in a number of neurons, including PVT, VD1-13, RID, AFD, ASK, RIV, RIB, PVQ, DVA, and RIS; zig-5::gfp is detected in the PVT neuron beginning at the three-fold stage of embryogenesis and continuing throughout larval development; loss of zig-5 activity in large-scale RNAi screens has been reported to result in low levels of embryonic lethality.
45	tag-329	C50F4.3	n/a	chrV 9,535,638	C. elegans TAG-329 protein; contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
46	F10F2.4	F10F2.4	n/a	chrIII 4,624,572	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
47	Y42A5A.4	Y42A5A.4	n/a	chrV 11,106,364	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
48	K06A4.2	K06A4.2	n/a	chrV 9,487,363	contains similarity to Pfam domains PF00293 (NUDIX domain) , PF05026 (Dcp2, box A domain) contains similarity to Interpro domains IPR015797 (NUDIX), IPR007722 (Dcp2, box A), IPR000086 (NUDIX hydrolase, core)
49	M04G7.1	M04G7.1	n/a	chrIV 456,400	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000877 (Proteinase inhibitor I12, Bowman-Birk), IPR003582 (Metridin-like ShK toxin)
50	Y39A3A.4	Y39A3A.4	n/a	chrIII 2,074,752	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)