UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	vps-37	CD4.4	5.0000000000000004e-105	chrV 5,593,134	C. elegans VPS-37 protein; contains similarity to Pfam domain PF07200 Modifier of rudimentary (Mod(r)) protein contains similarity to Interpro domain IPR009851 (Modifier of rudimentary, Modr)
2	C14H10.1	C14H10.1	n/a	chrX 10,235,306	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
3	pqn-20	C37A2.2	n/a	chrI 6,794,248	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
4	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
5	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
6	aspm-1	C45G3.1	n/a	chrI 9,224,107	The C45G3.1 gene encodes a protein, with one N-terminal calponin-like actin-binding domain and two IQ calmodulin-binding domains, that is likely to be required for spindle structure and function, and (indirectly) for neural function, based on its orthology to Drosophila ABNORMAL SPINDLE and on its joint sterile and uncoordinated RNAi phenotypes; C45G3.1 is also orthologous to human ASPM (OMIM:605481), which when mutated leads to primary microcephaly; C45G3.1 is required for embryonic and larval viability, germline maintenance, vulval morphogenesis, meiosis, and locomotion.
7	R12E2.1	R12E2.1	n/a	chrI 4,183,608	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF00651 (BTB/POZ domain) , PF07707 (BTB And C-terminal Kelch) , PF07646 (Kelch motif) (3)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR017096 (Kelch-like protein, gigaxonin), IPR000210 (BTB/POZ-like), IPR006652 (Kelch repeat type 1), IPR011333 (BTB/POZ fold), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013069 (BTB/POZ), IPR011705 (BTB/Kelch-associated), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
8	R05D11.6	R05D11.6	n/a	chrI 8,597,435	contains similarity to Clostridium perfringens Hypothetical protein CPE2542.; TR:Q8XHE3
9	M18.8	M18.8	n/a	chrIV 12,125,838	contains similarity to Pfam domain PF01529 DHHC zinc finger domain contains similarity to Interpro domains IPR001594 (Zinc finger, DHHC-type), IPR011527 (ABC transporter, transmembrane region, type 1)
10	srh-51	C10G11.3	n/a	chrI 6,301,375	C. elegans SRH-51 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	ath-1	K04G2.5	n/a	chrI 8,037,923	C. elegans ATH-1 protein; contains similarity to Pfam domain PF02230 Phospholipase/Carboxylesterase contains similarity to Interpro domains IPR003140 (Phospholipase/carboxylesterase), IPR003089 (Alpha/beta hydrolase)
12	mat-3	F10C5.1	n/a	chrIII 478,879	mat-3 encodes a tetratricopeptide repeat (TPR)-containing protein that is the C. elegans ortholog of CDC23/APC8, a conserved regulatory subunit of the anaphase-promoting complex; mat-3 activity is required for progression through metaphase of oocyte meiosis I, germline proliferation, and vulval development.
13	lin-23	K10B2.1	n/a	chrII 6,372,870	lin-23 encodes an F-box- and WD-repeat-containing protein orthologous to Saccharomyces cerevisiae MET30 and human beta TRCP (OMIM:603482), both components of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; LIN-23 negatively regulates postembryonic cell divsions in all tissue types, and specifically, has been shown to function cell autonomously in the vulva to negatively regulate cell cycle progression and allow for cell cycle exit; LIN-23 also functions cell autonomously in some neurons to regulate neurite outgrowth; LIN-23 expression is first detected broadly during gastrulation, with expression continuing postembryonically in body wall and enteric muscle, hypodermal cells, and many but not all neurons; LIN-23 localizes to the cytoplasm.
14	set-32	C41G7.4	n/a	chrI 9,520,403	set-32 encodes a divergent histone H3 lysine-9 (H3K9) methyltransferase homolog with a SET domain; SET-32 has no obvious non-nematode orthologs, but several paralogs (SET-6, SET-13, SET-15, SET-19, SET-20, and SET-21); set-32(ok1457) has no obvious mutant phenotype, and SET-32 has no obvious function in mass RNAi assays.
15	T01D3.5	T01D3.5	n/a	chrV 13,714,119	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
16	F52C9.7	F52C9.7	n/a	chrIII 5,309,798	contains similarity to Interpro domain IPR002226 (Catalase)
17	bag-1	F57B10.11	n/a	chrI 6,564,081	A homolog of the human BAG-family of co-chaperone proteins, negatively regulates Hsp70 and affects cell stress and cell growth.
18	F59A3.4	F59A3.4	n/a	chrI 5,508,149	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
19	rle-1	M142.6	n/a	chrIII 10,941,254	C. elegans RLE-1 protein; contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000694 (Proline-rich region), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
20	H04M03.1	H04M03.1	n/a	chrIV 5,897,858	contains similarity to Pfam domain PF00821 Phosphoenolpyruvate carboxykinase contains similarity to Interpro domains IPR013035 (Phosphoenolpyruvate carboxykinase, C-terminal), IPR008210 (Phosphoenolpyruvate carboxykinase, N-terminal), IPR008209 (Phosphoenolpyruvate carboxykinase, GTP-utilising)
21	Y48E1B.4	Y48E1B.4	n/a	chrII 13,562,596	contains similarity to Buchnera aphidicola Flagellar hook-length control protein.; SW:FLIK_BUCAP
22	F21H12.1	F21H12.1	n/a	chrII 6,098,704	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
23	AH9.3	AH9.3	n/a	chrX 2,259,841	contains similarity to Interpro domain IPR010916 (TonB box, conserved site)
24	F41C3.4	F41C3.4	n/a	chrII 4,740,995	contains similarity to Pfam domain PF04178 Got1-like family contains similarity to Interpro domain IPR007305 (Got1-like protein)
25	rom-1	F26F4.3	n/a	chrIII 4,907,987	C. elegans ROM-1 protein; contains similarity to Pfam domain PF01694 Rhomboid family contains similarity to Interpro domains IPR002610 (Peptidase S54, rhomboid), IPR017213 (Peptidase S54, rhomboid, metazoan)
26	T07G12.8	T07G12.8	n/a	chrIV 10,553,796	contains similarity to Thermoplasma volcanium ABC transport system permease protein P1P2A1A2.; TR:Q978R0
27	T13B5.3	T13B5.3	n/a	chrII 1,099,395	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domains IPR000560 (Histidine acid phosphatase), IPR002016 (Haem peroxidase, plant/fungal/bacterial)
28	H28G03.4	H28G03.4	n/a	chrX 5,223,420	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
29	H04D03.1	H04D03.1	n/a	chrIII 10,437,086	contains similarity to Saccharomyces cerevisiae Global transcription activator that acts in complex with Snf2p, Snf5p, Snf6p, and Swi3p to assist gene-specific activators; involved in the regulation of expression of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; SGD:YPL016W
30	bub-3	Y54G9A.6	n/a	chrII 13,727,744	C. elegans BUB-3 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
31	F17A9.3	F17A9.3	n/a	chrV 6,106,582	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
32	tac-1	Y54E2A.3	n/a	chrII 14,753,292	tac-1 encodes the sole C. elegans member of the transforming acidic coiled-coil (TACC) protein family whose members contain highly conserved C-terminal coiled-coil domains; during early embryogenesis, TAC-1 activity is essential for such microtubule-based processes as pronuclear migration and mitotic spindle elongation; TAC-1 interacts in vivo with, and mutually stabilizes, ZYG-9, a microtubule-associated protein (MAP) also required for pronuclear migration; TAC-1 also interacts with ZYG-8, a kinase domain-containing MAP required for proper spindle positioning during anaphase of the first embryonic cell division; TAC-1 is a core component of centrosomes, and also localizes to the meiotic spindle poles, the mitotic spindle, and the cytoplasm.
33	cpg-4	C10F3.1	n/a	chrV 5,997,803	cpg-4 encodes a large (782-residue), unfamiliar, putatively secreted protein with a C-terminal low-complexity domain; CPG-4 has 35 potential chondroitin attachment sites, mostly in its C-terminal half, 4 of which have been verified by mass spectrometry; CPG-4 has no obvious function in mass RNAi assays.
34	gta-1	K04D7.3	n/a	chrIV 10,182,270	The gta-1 gene encodes an ortholog of the human gene GABAT, which when mutated leads to GABA-transaminase deficiency (OMIM:137150).
35	F08F8.4	F08F8.4	n/a	chrIII 7,358,292	contains similarity to Interpro domain IPR001126 (UMUC-like DNA-repair protein)
36	exoc-7	C43E11.8	n/a	chrI 4,245,201	C. elegans EXOC-7 protein; contains similarity to Pfam domain PF03081 Exo70 exocyst complex subunit contains similarity to Interpro domain IPR004140 (Exo70 exocyst complex subunit)
37	bub-1	R06C7.8	n/a	chrI 7,253,581	bub-1 encodes a serine/threonine kinase orthologous to Saccharomyces cerevisiae BUB1 which is required for proper function of the mitotic spindle assembly checkpoint and human BUB1 (OMIM:602452) which is mutated in some colorectal cancers; BUB-1 activity is required at several stages of development, including embryogenesis; BUB-1 is expressed predominantly in the anterior of the embryo and in hypodermal seam cells during the L1 and L2 larval stages.
38	Y18D10A.1	Y18D10A.1	n/a	chrI 12,797,263	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding)
39	mlh-1	T28A8.7	n/a	chrIII 13,511,833	The mlh-1 gene encodes a DNA mismatch repair protein homolog that is orthologous to human MLH1.
40	cyp-14A4	R04D3.1	n/a	chrX 13,283,058	C. elegans CYP-14A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
41	hsr-9	T05F1.6	n/a	chrI 9,628,707	hsr-9 encodes a protein containing a BRCT (BRCA 1 C terminus) domain that is found in proteins that regulate the cell cycle checkpoint in response to DNA damage; HSR-9 activity is required for a normal response to DNA damage caused by gamma-irradiation; loss of HSR-9 function via RNA-mediated interference after gamma-irradiation results in defects in mitotic cell cycle arrest, reduction of apoptosis of pachytene nuclei, and radiation sensitivity of progeny; the expression pattern and subcellular localization of HSR-9 are not yet known.
42	cin-4	ZK1127.7	n/a	chrII 7,039,709	C. elegans CIN-4 protein
43	C43D7.4	C43D7.4	n/a	chrV 19,322,158	contains similarity to Saccharomyces cerevisiae Protein of unknown function, rich in asparagine residues; SGD:YDL167C
44	F56A6.4	F56A6.4	n/a	chrI 622,086
45	ZK686.4	ZK686.4	n/a	chrIII 7,769,518	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR007087 (Zinc finger, C2H2-type)
46	T22B11.2	T22B11.2	n/a	chrIV 4,690,180	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
47	pqn-59	R119.4	n/a	chrI 377,739	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
48	T16G12.6	T16G12.6	n/a	chrIII 10,072,699	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
49	Y106G6D.7	Y106G6D.7	n/a	chrI 10,126,327	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR000694 (Proline-rich region), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
50	smc-4	F35G12.8	n/a	chrIII 4,590,281	The smc-4 gene encodes a homolog of the SMC4 subunit of mitotic condensin; SMC-4 acts with MIX-1 to enable chromosome segregation.