UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	abch-1	C56E6.5	0	chrII 6,530,223	C. elegans ABCH-1 protein; contains similarity to Interpro domain IPR003439 (ABC transporter-like)
2	F28G4.3	F28G4.3	n/a	chrV 16,286,908	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
3	unc-7	R07D5.1	n/a	chrX 15,134,407	unc-7 encodes an innexin required for gap junction formation in invertebrates; UNC-7 is also required for normal locomotion, egg-laying, inhibition of feeding by tapping, avermectin sensitivity, and ivermectin sensitivity, as well as for the antagonism of UNC-79 and UNC-80 activity by volatile anesthetics; unc-7 is genetically required, and transcribed in, neurons rather than muscle cells, from larval stages L1 through L4; homologs of UNC-7 include Drosophila OGRE and SHAKING-B, as well as 24 C. elegans paralogs (including EAT-5, UNC-9, and INX-1 through INX-20); UNC-7 genetically interacts with UNC-124, and unc-7 mutants are phenotypically similar to unc-9 and unc-124 mutants; UNC-7 genetically interacts with AVR-14 and GLC-1 in the response to ivermectin.
4	gnrr-3	ZC374.1	n/a	chrX 10,050,904	C. elegans GNRR-3 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
5	C36C9.5	C36C9.5	n/a	chrX 1,701,859
6	C34F6.10	C34F6.10	n/a	chrX 11,233,244	contains similarity to Pfam domain PF00041 Fibronectin type III domain contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR000694 (Proline-rich region)
7	T23F4.1	T23F4.1	n/a	chrII 1,167,834	contains similarity to Pfam domain PF01738 Dienelactone hydrolase family contains similarity to Interpro domain IPR002925 (Dienelactone hydrolase)
8	zag-1	F28F9.1	n/a	chrIV 3,858,673	zag-1 encodes a homeodomain protein of the ZFH class which consists of a homeodomain flanked by two clusters of C2H2-type zinc fingers and is related to transcriptional repressors encoded by Drosophila zfh-1 and the vertebrate ZEB genes; ZAG-1 is required for locomotion, for neuronal differentiation, and for proper axonal branching and fasciculation; from late embryogenesis through adult stages of development, ZAG-1 is expressed dynamically in head and tail neurons and in the intestinal and anal depressor muscles.
9	pax-2	K06B9.5	n/a	chrIV 4,202,013	C. elegans PAX-2 protein; contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
10	K09H11.4	K09H11.4	n/a	chrV 5,724,796	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
11	W05B2.7	W05B2.7	n/a	chrIII 10,989,906	contains similarity to Interpro domain IPR000533 (Tropomyosin)
12	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
13	rab-11.2	W04G5.2	n/a	chrI 11,633,357	C. elegans RAB-11.2 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily)
14	Y66A7A.2	Y66A7A.2	n/a	chrIII 11,486,326	Y66A7A.2 encodes an ortholog of Pop5, a protein subunit shared by the endoribonucleases RNase MRP and RNAse P; RNAse MRP cleaves mitochondrial RNA in mitochondrial DNA synthesis, nucleolar pre-rRNA in ribosome synthesis, and at least one mRNA (CLB2) involved in cell-cycle regulation; RNAse P cleaves tRNA precursors to produce their mature 5' end; Y66A7A.2 is evolutionarily ubiquitous among eukaryotes.
15	srd-45	F17A2.7	n/a	chrX 12,329,674	C. elegans SRD-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	srh-207	ZK262.1	n/a	chrV 18,409,607	C. elegans SRH-207 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	F01G10.7	F01G10.7	n/a	chrIV 10,240,539	contains similarity to Pfam domains PF04083 (ab-hydrolase associated lipase region) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR006693 (AB-hydrolase associated lipase region), IPR000073 (Alpha/beta hydrolase fold-1), IPR008262 (Lipase, active site)
18	K07H8.5	K07H8.5	n/a	chrIV 8,272,091
19	fbxa-153	B0391.5	n/a	chrV 15,608,029	fbxa-153 encodes a protein with an N-terminal F-box domain and a C-terminal FTH domain; FBXA-153 has no obvious non-nematode orthologs; FBXA-153 shares N-terminal UNC-13 binding, and thus may share at least some functions, with ERI-1, W04D2.6, and Y55F3AM.13; FBXA-153 has no obvious function in mass RNAi assays.
20	srx-134	F09F3.7	n/a	chrV 13,855,910	C. elegans SRX-134 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
21	srab-7	C36C5.11	n/a	chrV 3,154,327	C. elegans SRAB-7 protein ;
22	tag-89	H02I12.3	n/a	chrIV 11,395,562	C. elegans TAG-89 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
23	F32D8.1	F32D8.1	n/a	chrV 10,882,070	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
24	clec-263	F26F2.6	n/a	chrV 20,571,518	C. elegans CLEC-263 protein; contains similarity to Pfam domains PF08277 (PAN-like domain) (2), PF00024 (PAN domain) contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
25	clk-1	ZC395.2	n/a	chrIII 5,278,572	clk-1 encodes the C. elegans ortholog of COQ7/CAT5, a highly conserved demethoxyubiquinone (DMQ) hydroxylase that is necessary for the biosynthesis of ubiquinone (coenzyme Q, Q9) from 5-demethoxyubiquinone (DMQ9); in C. elegans, CLK-1 activity is required for normal physiological rates of growth, development, behavior, and aging, as well as for normal brood sizes.
26	F45F2.6	F45F2.6	n/a	chrV 8,527,305	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
27	srbc-59	R09E12.1	n/a	chrV 779,433	C. elegans SRBC-59 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
28	ZC487.3	ZC487.3	n/a	chrV 6,723,598
29	srt-16	C50H11.11	n/a	chrV 3,064,037	C. elegans SRT-16 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
30	srw-136	K12D9.10	n/a	chrV 3,009,736	C. elegans SRW-136 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
31	inx-20	T23H4.1	n/a	chrI 9,877,813	C. elegans INX-20 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
32	ZK1128.7	ZK1128.7	n/a	chrIII 10,137,921	contains similarity to Pfam domain PF00011 Hsp20/alpha crystallin family contains similarity to Interpro domains IPR002068 (Heat shock protein Hsp20), IPR008978 (HSP20-like chaperone), IPR001436 (Alpha crystallin/Heat shock protein)
33	F13E9.8	F13E9.8	n/a	chrIV 10,893,972	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
34	fbxa-171	C38D9.1	n/a	chrV 17,564,573	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
35	srt-47	Y41E3.12	n/a	chrIV 15,051,352	C. elegans SRT-47 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR006121 (Heavy metal transport/detoxification protein)
36	F35A5.5	F35A5.5	n/a	chrX 3,794,638	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
37	col-123	W08D2.6	n/a	chrIV 9,822,477	col-123 is homologous to the human gene A TYPE IV COLLAGEN (COL6A1; OMIM:303631), which when mutated is sometimes associated with diffuse leiomyomatosis.
38	ric-19	C32E8.7	n/a	chrI 3,779,897	The ric-19 gene encodes an evolutionarily conserved cytosolic protein involved in neuroendocrine secretion via association with secretory vesicles.
39	F40A3.5	F40A3.5	n/a	chrV 7,869,571	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
40	rsr-1	F28D9.1	n/a	chrI 11,179,945	C. elegans RSR-1 protein; contains similarity to Pfam domain PF01480 PWI domain contains similarity to Interpro domains IPR002483 (Splicing factor PWI), IPR000694 (Proline-rich region), IPR005819 (Histone H5), IPR002185 (Dopamine D4 receptor)
41	ZK896.4	ZK896.4	n/a	chrIV 12,881,875	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
42	C07C7.1	C07C7.1	n/a	chrIV 9,184,575	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_0790.; TR:Q98RD0
43	F46A8.6	F46A8.6	n/a	chrI 11,244,411	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
44	Y16B4A.2	Y16B4A.2	n/a	chrX 14,766,829	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
45	ncx-5	Y32F6B.2	n/a	chrV 10,488,232	ncx-5 encodes a putative 4Na[+]/1Ca[2+],1K[+] exchanger, orthologous to human SLC24A1-5 and paralogous to NCX-4; NCX-5 is predicted to export free cytoplasmic Ca[2+] with low affinity but high capacity, being complemented by low-capacity/high-affinity Ca[2+] ATPase pumps such as MCA-1/-3; NCX-5 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-5 has no obvious function in mass RNAi assays.
46	F18F11.4	F18F11.4	n/a	chrIV 332,622	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
47	T08G3.6	T08G3.6	n/a	chrV 16,446,543	contains similarity to Interpro domain IPR008975 ()
48	srbc-2	C04E12.9	n/a	chrV 3,375,717	C. elegans SRBC-2 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
49	R04A9.3	R04A9.3	n/a	chrX 378,980
50	scd-2	T10H9.2	n/a	chrV 6,636,446	C. elegans SCD-2 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR002919 (Protease inhibitor I8, cysteine-rich trypsin inhibitor-like), IPR000998 (MAM), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)