UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sulp-1	C55B7.6	0	chrI 6,484,156	sulp-1 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-1 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-1::GFP transcriptional fusion is expressed strongly in several neurons, weakly in hypodermal cells and the intestine, and very faintly in the excretory cell and body wall muscle.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F57B10.9	F57B10.9	n/a	chrI 6,551,594	F57B10.9 is orthologous to the human gene SPARTIN (TAHCCP1; OMIM:607111), which when mutated leads to disease.
4	dgk-3	F54G8.2	n/a	chrIII 9,165,462	dgk-3 encodes a diacylglycerol kinase that is the C. elegans ortholog of mammalian DGK-beta; dgk-3 activity is required for regulation of long-term thermotactic behavioral plasticity and for regulation of olfactory adaptation; large-scale expression studies have reported dgk-3 expression in head neurons, the intestine, and the pharyngeal lumen, while expression profiling indicates that dgk-3 is expressed in the AFD thermosensory neurons as well as a small number of additional sensory neurons.
5	ZK863.1	ZK863.1	n/a	chrV 12,169,192	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
6	lgc-18	T01H10.7	n/a	chrX 12,126,727	C. elegans LGC-18 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
7	srz-54	Y102A5C.25	n/a	chrV 16,981,243	C. elegans SRZ-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
8	aco-1	ZK455.1	n/a	chrX 11,341,447	aco-1 encodes an aconitase that is homologous to mammalian iron regulatory protein-1 (IRP1); aco-1 activity is required for normal brood sizes and, under iron stress conditions, for normal lifespan and L4-to-adult growth rates; ACO-1 physically interacts with GEX-3; like IRP1, ACO-1 has aconitase activity and is post-translationally regulated by iron, but, unlike IRP1, it lacks RNA-binding activity; ACO-1 is predicted to be mitochondrial, and its mRNA levels appear to decrease in response to iron treatment.
9	T11F9.12	T11F9.12	n/a	chrV 11,494,950	contains similarity to Interpro domain IPR011735 (Conserved hypothetical protein, HtrL)
10	F42C5.6	F42C5.6	n/a	chrIV 7,308,755
11	mys-1	VC5.4	n/a	chrV 7,083,085	mys-1 encodes a MYST family histone acetyltransferase orthologous to Drosophila EG0007.7, human TIP60, and S. cerevisiae Esa1p; during vulval development, mys-1 acts as Class C synMuv gene: mys-1 mutations enhance mutations in components of the C. elegans NuRD and Rb repressor complexes that negatively regulate expression of genes required for vulval induction; in addition, mys-1(RNAi) enhances mutations in pha-4, which encodes a FoxA transcription factor required for pharyngeal organogenesis; mys-1 mutations also cause a synthetic slow growth phenotype in combination with mutations in the MCD-1 zinc-finger protein; thus, mys-1 activity is essential for proper cell fate specification of different cell types at different times during C. elegans development.
12	C09B8.4	C09B8.4	n/a	chrX 6,019,168	contains similarity to Pfam domain PF05705 Eukaryotic protein of unknown function (DUF829) contains similarity to Interpro domain IPR008547 (Protein of unknown function DUF829, eukaryotic)
13	hsp-6	C37H5.8	n/a	chrV 4,825,414	hsp-6 encodes a mitochondrial-specific chaperone that is a member of the DnaK/Hsp70 superfamily of molecular chaperones; hsp-6 is believed to be involved in the mitochondrial unfolded protein response, as hsp-6 expression, normally broadly detected from the L1 larval through adult stages of development, is greatly increased in response to treatments that disrupt mitochondrial protein handling; loss of hsp-6 activity via RNAi results in severe growth defects with arrest at embryonic and early larval stages of development.
14	W03C9.5	W03C9.5	n/a	chrII 11,967,205	contains similarity to Arabidopsis thaliana F25C20.11 protein.; TR:Q9SAA3
15	tsp-3	Y39E4B.4	n/a	chrIII 13,213,403	C. elegans TSP-3 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domain IPR000301 (CD9/CD37/CD63 antigen)
16	F09E5.10	F09E5.10	n/a	chrII 5,349,294	contains similarity to Interpro domain IPR009079 (Four-helical cytokine-like, core)
17	far-5	F15B9.3	n/a	chrV 12,996,198	far-5 encodes a member of a class of fatty acid-and retinol-binding proteins that are known to be secreted by parasitic nematodes and plants; far-5 binds lipid in fluorescence-based assays, however, the precise function of far-5 is not known.
18	ace-2	Y44E3A.2	n/a	chrI 3,304,491	An acetylcholineesterase involved in the termination of cholinergic nerve transmission; it is predominantly expressed in motoneurons.
19	ZK643.1	ZK643.1	n/a	chrIII 8,934,736	contains similarity to Pfam domain PF00339 Arrestin (or S-antigen), N-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011021 (Arrestin-like, N-terminal)
20	K02E10.7	K02E10.7	n/a	chrX 2,504,770	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
21	F31D5.4	F31D5.4	n/a	chrII 4,179,466	contains similarity to Pfam domain PF01825 Latrophilin/CL-1-like GPS domain contains similarity to Interpro domain IPR000203 (GPS)
22	T26E4.7	T26E4.7	n/a	chrV 15,794,497	contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	F09G2.2	F09G2.2	n/a	chrV 7,197,657	contains similarity to Interpro domain IPR011028 (Cyclin-like)
24	srg-8	T12A2.9	n/a	chrIII 6,254,139	C. elegans SRG-8 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
25	str-56	T06C12.3	n/a	chrV 15,873,145	C. elegans STR-56 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003569 (Cytochrome c-type biogenesis protein CcbS)
26	gcy-22	T03D8.5	n/a	chrV 20,818,085	gcy-22 is predicted to encode a guanylate cyclase.
27	clec-9	Y70C5C.2	n/a	chrV 16,705,835	C. elegans CLEC-9 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	F46B3.16	F46B3.16	n/a	chrV 20,630,275
29	F54H5.5	F54H5.5	n/a	chrII 6,625,330
30	gcy-19	C17F4.6	n/a	chrII 3,254,897	gcy-19 encodes a predicted transmembrane guanylyl cyclase; as loss of gcy-19 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-19 in C. elegans development and/or behavior is not yet known; by sequence similarity, however, GCY-19 can be predicted to function in chemosensory signal transduction.
31	acs-17	C46F4.2	n/a	chrX 5,939,959	C. elegans ACS-17 protein; contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
32	sri-16	F15H9.4	n/a	chrI 12,149,485	C. elegans SRI-16 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	his-32	F17E9.10	n/a	chrIV 8,334,513	his-32 encodes an H3 histone; by homology, HIS-32 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-32 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
34	grl-13	F32D1.4	n/a	chrV 4,363,652	grl-13 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-13 is expressed in larval arcade cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
35	C03E10.3	C03E10.3	n/a	chrV 11,287,593	contains similarity to Clostridium perfringens Probable cytochrome C-type biogenesis protein.; TR:Q8XME8
36	K03H6.4	K03H6.4	n/a	chrIV 1,519,644
37	K08F4.5	K08F4.5	n/a	chrIV 10,135,380	contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_96, whole genome shotgun sequence.; TR:A0EH68
38	mog-4	C04H5.6	n/a	chrII 14,556,957	The mog-4 gene encodes a DEAH helicase orthologous to the Drosophila CG10689 and the S. cerevisiae PRP2 proteins.
39	Y54E2A.4	Y54E2A.4	n/a	chrII 14,754,890	contains similarity to Archaeoglobus fulgidus NADH oxidase (NOXA-3).; TR:O29847
40	T16H12.2	T16H12.2	n/a	chrIII 10,086,574	contains similarity to Mus musculus 2310010I16Rik protein.; TR:Q9CWH8
41	T23C6.3	T23C6.3	n/a	chrX 17,137,111
42	clec-102	F33E2.3	n/a	chrI 12,579,521	C. elegans CLEC-102 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
43	F10E7.6	F10E7.6	n/a	chrII 7,113,277
44	T20B6.2	T20B6.2	n/a	chrIII 2,895,298	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003125 (Protein of unknown function WSN)
45	K10C2.6	K10C2.6	n/a	chrX 6,451,568
46	F46G11.1	F46G11.1	n/a	chrX 5,794,401	F46G11.1 is orthologous to the human gene TRUNCATED PUTATIVE T7-LIKE MITOCHONDRIAL DNA HELICASE (C10orf2; OMIM:606075), which when mutated leads to disease.
47	T05E8.3	T05E8.3	n/a	chrI 5,475,882	The T05E8.3 gene encodes a divergent DEAH helicase that is (apparently) unique to Caenorhabditis; it has no well-characterized orthologs in the complete Drosophila or S. cerevisiae genomes, and no obvious orthologs in the draft human genome sequence either.
48	hhat-2	Y57G11C.17	n/a	chrIV 14,827,743	C. elegans HHAT-2 protein; contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
49	irk-2	M02A10.2	n/a	chrX 706,700	irk-2 encodes an inwardly rectifying potassium channel based on sequence homology to the the human potassium channel genes KCNJ1/KCNJ2.
50	R07G3.8	R07G3.8	n/a	chrII 7,619,307	contains similarity to Pfam domain PF07159 Protein of unknown function (DUF1394) contains similarity to Interpro domain IPR009828 (Protein of unknown function DUF1394)