UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	tag-294	C54H2.3	9.999999999999999e-167	chrX 5,761,796	C. elegans TAG-294 protein; contains similarity to Pfam domain PF00641 Zn-finger in Ran binding protein and others contains similarity to Interpro domain IPR001876 (Zinc finger, RanBP2-type)
2	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
3	clec-238	Y102A5C.17	n/a	chrV 16,952,706	C. elegans CLEC-238 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
4	B0280.7	B0280.7	n/a	chrIII 7,111,015
5	grd-11	K02E2.2	n/a	chrV 20,356,705	grd-11 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, four Ground domains, an short region of low-complexity sequence, and a Hint/Hog domain; the Hint/Hog domain is predicted to cut GRD-2 into two halves and then covalently link cholesterol to the C-terminus of the Ground domain; the four N-terminal Ground domains are predicted to form one or more cysteine-crosslinked proteins involved in intercellular signalling; Ground domains have subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; grd-11 has no obvious function in RNAi assays.
6	unc-39	F56A12.1	n/a	chrV 14,374,572	unc-39 encodes a homeodomain transcription factor that belongs to the Six4/5 family of homeodomain proteins that includes human Six5; UNC-39 is required for axonal pathfinding in anterior-derived neurons and for specification of most mesodermal cell types and may regulate a developmental decision between migration and differentiation; UNC-39 is expressed in the embryo in anterior neurons, posteriorly derived mesoderm (somatic gonad, M mesoblast, and possibly the coelomocytes and muIntR), the CAN neurons, and body wall muscle.
7	nhr-230	Y17D7A.1	n/a	chrV 18,849,704	C. elegans NHR-230 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	F48A11.2	F48A11.2	n/a	chrII 198,605
9	T23F6.2	T23F6.2	n/a	chrIV 12,722,330
10	clec-247	Y51A2A.1	n/a	chrV 18,285,606	C. elegans CLEC-247 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
11	C34D4.13	C34D4.13	n/a	chrIV 7,133,813
12	R07A4.2	R07A4.2	n/a	chrX 10,745,349	contains similarity to Rhodopirellula baltica Probable serine/threonine-protein kinase pknB (EC 2.7.1.-).; TR:Q7UFE6
13	F15D4.4	F15D4.4	n/a	chrII 13,241,088	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
14	apc-11	F35G12.9	n/a	chrIII 4,594,070	apc-11 encodes a predicted key catalytic subunit of the anaphase promoting complex that is required for embryonic development past the embryonic one- cell stage.
15	Y62H9A.7	Y62H9A.7	n/a	chrX 11,885,307	contains similarity to Mus musculus Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterases1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE).; SW:CN1A_MOUSE
16	cnk-1	R01H10.8	n/a	chrIII 10,274,812	cnk-1 encodes a protein that contains a SAM domain, a PDZ domain, and a PH domain.
17	srd-17	Y2H9A.2	n/a	chrV 13,431,663	C. elegans SRD-17 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	ZK792.7	ZK792.7	n/a	chrIV 11,695,365	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domain IPR004843 (Metallophosphoesterase)
19	glb-20	R01E6.6	n/a	chrX 13,554,276	glb-20 encodes a globin; glb-20 transcription is higher in L3 and dauers than in young adults; glb-20 has no obvious function in mass RNAi assays.
20	srd-50	F15A2.4	n/a	chrX 13,480,135	C. elegans SRD-50 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	srxa-9	ZK678.4	n/a	chrX 15,749,493	C. elegans SRXA-9 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
22	srt-45	M162.3	n/a	chrV 19,780,434	C. elegans SRT-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
23	ndx-3	Y38A8.1	n/a	chrII 4,954,109	The ndx-3 gene encodes a homolog of peroxisomal CoA diphosphatases in both S. cerevisiae (PCD1) and C. elegans (NDX-8); more generally, NDX-3 protein belongs to the family of NUDIX hydrolases.
24	C33D3.4	C33D3.4	n/a	chrX 10,488,757	contains similarity to Buchnera aphidicola Exodeoxyribonuclease V beta chain (EC 3.1.11.5).; SW:EX5B_BUCAP
25	W02B8.1	W02B8.1	n/a	chrII 13,900,226
26	srx-133	F09F3.4	n/a	chrV 13,849,303	C. elegans SRX-133 protein ;
27	C11G6.2	C11G6.2	n/a	chrX 16,329,525	contains similarity to Interpro domain IPR003593 (AAA+ ATPase, core)
28	sri-77	D2062.9	n/a	chrII 2,604,314	C. elegans SRI-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	F40E3.6	F40E3.6	n/a	chrI 2,651,225
30	srw-112	K12D9.9	n/a	chrV 3,005,101	C. elegans SRW-112 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
31	C46H11.1	C46H11.1	n/a	chrI 5,055,865
32	T21H8.5	T21H8.5	n/a	chrX 13,878,684	contains similarity to Interpro domain IPR000515 (Binding-protein-dependent transport systems inner membrane component)
33	M01H9.1	M01H9.1	n/a	chrIV 4,487,922	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related)
34	Y38H8A.5	Y38H8A.5	n/a	chrIV 13,467,731	The Y38H8A.5 gene encodes a homolog of the human gene ZNF195 (or p57KIP2), which when mutated leads to Beckwith-Wiedemann syndrome (OMIM:130650).
35	srh-283	C47A10.2	n/a	chrV 17,766,031	C. elegans SRH-283 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	D1005.2	D1005.2	n/a	chrX 1,460,943	contains similarity to Pfam domain PF01704 UTP--glucose-1-phosphate uridylyltransferase contains similarity to Interpro domains IPR016267 (UTP--glucose-1-phosphate uridylyltransferase, subgroup), IPR002618 (UTP--glucose-1-phosphate uridylyltransferase)
37	W03H9.3	W03H9.3	n/a	chrII 14,143,131	contains similarity to Streptomyces avermitilis Putative oxidoreductase.; TR:Q82DU1
38	Y6E2A.1	Y6E2A.1	n/a	chrV 15,710,013	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000832 (GPCR, family 2, secretin-like)
39	D1007.8	D1007.8	n/a	chrI 4,604,894	contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold)
40	K07D4.4	K07D4.4	n/a	chrII 4,032,008
41	lgc-7	Y57G11C.2	n/a	chrIV 14,712,127	C. elegans LGC-7 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
42	clec-245	C31G12.2	n/a	chrV 18,187,150	C. elegans CLEC-245 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
43	tag-83	F46F11.3	n/a	chrI 5,602,718	C. elegans TAG-83 protein ; contains similarity to Homo sapiens TNS1 protein; ENSEMBL:ENSP00000308321
44	Y39A1A.20	Y39A1A.20	n/a	chrIII 10,699,807
45	W04A8.1	W04A8.1	n/a	chrI 13,837,656	W04A8.1 encodes a protein weakly similar to human microcephalin (MCPH1; OMIM:607117, mutated in primary microcephaly); while their primary sequence similarity is very subtle (only being detectable with psi-BLAST on NCBI-nr, using C. briggsae CBG13622 as a query sequence), both W04A8.1 and microcephalin has similar ordering of BRCT domains (one N-terminal, two C-terminal); W04A8.1 has no obvious function in mass RNAi screens.
46	D1007.9	D1007.9	n/a	chrI 4,591,009
47	sqv-8	ZK1307.5	n/a	chrII 9,648,550	The sqv-8 gene encodes a glucuronyl transferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-8 is homologous to three distinct glucuronyl transferases (GlcAT-I, GlcAT-P and GlcAT-D) that play a role in the synthesis of different glycoconjugates; the common requirement for SQV-8 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
48	srx-68	K07C6.11	n/a	chrV 3,913,635	C. elegans SRX-68 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
49	K04E7.1	K04E7.1	n/a	chrX 6,462,585
50	srz-47	Y68A4A.2	n/a	chrV 17,191,554	C. elegans SRZ-47 protein ;