UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ftn-1	C54F6.14	9.000000000000001e-82	chrV 7,547,023	ftn-1 encodes one of two C. elegans ferritin heavy chain homologs; ftn-1 activity is essential for normal lifespan under iron stress conditions and, in addition, has been reported to be essential for embryogenesis; an ftn-1::gfp reporter is expressed in the intestine at all stages of development and its expression, as well as that of ftn-1 mRNA, increases under iron stress conditions and in the background of mutations in the second ferritin-encoding gene, ftn-2.
2	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
3	ora-1	F57H12.3	n/a	chrIV 7,978,407	C. elegans ORA-1 protein ; contains similarity to Onchocerca volvulus OV39 antigen (Fragment).; SW:P31730
4	acs-2	F28F8.2	n/a	chrV 15,568,615	C. elegans ACS-2 protein; contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
5	F22B5.4	F22B5.4	n/a	chrII 8,451,121	contains similarity to Pseudomonas putida Butylphenol hydroxylase component A1.; TR:Q842G6
6	F15E6.3	F15E6.3	n/a	chrIV 4,295,274	contains similarity to Cryptococcus neoformans Glycine-rich RNA binding protein, putative.; TR:Q5KDS6
7	cnc-2	R09B5.3	n/a	chrV 1,449,921	cnc-2 encodes one of six C. elegans caenacin peptides; cnc-2 expression is strongly induced after infection by the fungus Drechmeria coniospora and the gram-negative bacteria Serratia marcescens, suggesting that it functions as a secreted antimicrobial peptide in the innate immune response.
8	ZK970.7	ZK970.7	n/a	chrII 10,312,538	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
9	E04F6.9	E04F6.9	n/a	chrII 7,211,856
10	dct-7	F15E6.8	n/a	chrIV 4,290,416	C. elegans DCT-7 protein ;
11	T28A11.19	T28A11.19	n/a	chrV 3,269,156	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
12	F40G12.5	F40G12.5	n/a	chrV 14,269,931	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
13	grd-4	T01B10.1	n/a	chrX 8,501,684	grd-4 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-4 is weakly required for normal molting; GRD-4 is also required for normal adult alae formation, growth to full size, and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
14	fipr-24	C37A5.8	n/a	chrI 14,157,799	C. elegans FIPR-24 protein ;
15	C33G8.3	C33G8.3	n/a	chrV 7,007,900	contains similarity to Interpro domain IPR009149 (BR22)
16	C34C6.7	C34C6.7	n/a	chrII 8,707,892	contains similarity to Interpro domain IPR000533 (Tropomyosin)
17	col-84	K12D12.3	n/a	chrII 11,869,021	C. elegans COL-84 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
18	T20D4.11	T20D4.11	n/a	chrV 3,399,039	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
19	col-45	F53G12.7	n/a	chrI 116,588	col-45 encodes a cuticle collagen.
20	scl-11	F49E11.6	n/a	chrIV 13,051,732	C. elegans SCL-11 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
21	C30F12.3	C30F12.3	n/a	chrI 6,971,092
22	F16B4.7	F16B4.7	n/a	chrV 1,585,902	contains similarity to Drosophila melanogaster Flybase gene name is CG7294-PA;; FLYBASE:CG7294
23	nlp-29	B0213.4	n/a	chrV 3,984,616	nlp-29 encodes a neuropeptide-like protein; nlp-29 appears to play a role in innate immunity, as its expression is strongly induced following bacterial and fungal infection; nlp-29 is expressed in the hypodermis and in the intestine; nlp-29 expression is regulated by TIR-1, an ortholog of SARM, a Toll-interleukin 1 receptor (TIR) domain protein, and by the RAB-1 GTPase and the product of R53.4, a mitochondrial ATP synthase subunit f homolog.
24	F22B7.9	F22B7.9	n/a	chrIII 8,653,148
25	grl-19	R02D3.6	n/a	chrIV 252,252	grl-19 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-19 is expressed in intestine; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
26	cpr-2	F36D3.9	n/a	chrV 16,533,516	C. elegans CPR-2 protein; contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
27	C18A11.1	C18A11.1	n/a	chrX 8,069,882
28	F09F7.6	F09F7.6	n/a	chrIII 5,551,674
29	F21C10.10	F21C10.10	n/a	chrV 9,096,675	contains similarity to Interpro domain IPR016040 (NAD(P)-binding)
30	F55G1.7	F55G1.7	n/a	chrIV 7,467,673
31	col-35	C15A11.1	n/a	chrI 7,386,359	col-35 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens; the amino- and carboxyl-terminal cysteine-rich regions of COL-35 are most closely related to those of COL-8, COL-19, and COL-39.
32	B0507.8	B0507.8	n/a	chrV 8,761,695	contains similarity to Schizosaccharomyces pombe Nucleoporin nup211 (Nuclear pore protein nup211).; SW:O74424
33	scl-5	C39E9.2	n/a	chrIV 13,064,550	C. elegans SCL-5 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
34	ZK971.1	ZK971.1	n/a	chrII 10,279,516	contains similarity to Arabidopsis thaliana Gb\|AAB67622.1.; TR:Q9LT65
35	F58E10.7	F58E10.7	n/a	chrV 13,993,064	contains similarity to Xenopus laevis FK506-binding protein.; TR:Q9I8P8
36	lys-3	Y22F5A.6	n/a	chrV 10,282,795	lys-3 encodes one of a family of ten C. elegans lysozyme genes that are homologous to lysozymes in the amoeboid protozoon Entamoeba histolytica.
37	nlp-28	B0213.3	n/a	chrV 3,988,091	C. elegans NLP-28 protein ; contains similarity to Ixodes scapularis Putative secreted salivary gland peptide.; TR:Q5Q982
38	dod-3	C24B9.9	n/a	chrV 2,730,844	C. elegans DOD-3 protein ;
39	nlp-32	F30H5.2	n/a	chrIII 486,349	C. elegans NLP-32 protein; contains similarity to Interpro domain IPR002952 (Eggshell protein)
40	cpi-1	K08B4.6	n/a	chrIV 6,093,107	cpi-1 encodes a homolog of cysteine protease inhibitors (cystatins); cpi-1 is at least superficially dispensable for viability and gross morphology.
41	nlp-12	M01D7.5	n/a	chrI 1,843,618	nlp-12 encodes two predicted neuropeptide-like proteins; nlp-12 is part of a LQFamide neuropeptide family that has members in at least one other nematode species; nlp-12 is expressed in one tail neuron; as loss of nlp-12 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-12-encoded peptides in development and/or behavior is not yet known.
42	grl-17	C56A3.1	n/a	chrV 13,562,991	grl-17 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-17 is expressed in pharynx, rectal epithelium, amphid socket cells, larval arcade cells, and larval hypodermis; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
43	nlp-35	C33A12.2	n/a	chrIV 9,518,633	C. elegans NLP-35 protein ;
44	cnc-1	R09B5.2	n/a	chrV 1,444,163	cnc-1 encodes one of six C. elegans caenacin peptides; CNC-1 is predicted to be a secreted protein that, based upon similarity to CNC-2, -4, and -6, may function as an antimicrobial peptide in the innate immune response.
45	W06G6.11	W06G6.11	n/a	chrV 16,648,635	contains similarity to Mus musculus Calsyntenin-1 precursor.; SW:CLS1_MOUSE
46	C35C5.9	C35C5.9	n/a	chrX 11,536,770	contains similarity to Haemophilus influenzae Monofunctional biosynthetic peptidoglycan transglycosylases(EC 2.4.2.-) (Monofunctional TGase).; SW:MTGA_HAEIN
47	C49H3.3	C49H3.3	n/a	chrIV 7,924,622	contains similarity to Xenopus tropicalis UPF0446 protein C12orf31 homolog.; SW:Q6NVR5
48	col-158	D2023.7	n/a	chrV 11,830,378	C. elegans COL-158 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
49	F53A9.1	F53A9.1	n/a	chrX 8,711,652	contains similarity to Interpro domains IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR002395 (HMW kininogen)
50	W09G12.7	W09G12.7	n/a	chrIV 1,230,204	contains similarity to Interpro domains IPR005819 (Histone H5), IPR002038 (Osteopontin)