UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C54E10.6	C54E10.6	5e-59	chrV 18,808,334	contains similarity to Saccharomyces cerevisiae Spindle Pole Component of molecular weight 24kDa; SGD:YMR117C
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	C05E11.3	C05E11.3	n/a	chrX 4,580,554	contains similarity to Mus musculus Lysosomal-associated transmembrane protein 4A (Golgi 4-transmembranesspanning transporter) (Mouse transporter protein) (MTP).; SW:Q60961
4	unc-119	M142.1	n/a	chrIII 10,907,547	unc-119 encodes a novel protein that is highly conserved amongst metazoans; unc-119 activity is required for proper development of the nervous system, including axonal branching and fasciculation, and hence, for normal movement, chemosensation, and feeding; unc-119 is expressed pan-neuronally beginning in the early embryo (~60 cells) and continuing through adulthood; although the molecular function of UNC-119 is not yet known, human UNC119, which can rescue C. elegans unc-119 mutant animals, is reported to function as a receptor-associated activator of signal transduction; thus, UNC-119 may be part of a signal transduction pathway that mediates axonal patterning in response to external developmental cues.
5	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
6	nhr-194	F59E11.8	n/a	chrV 8,969,321	C. elegans NHR-194 protein; contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	sdz-18	F45C12.11	n/a	chrII 1,705,740	C. elegans SDZ-18 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
8	lim-7	C04F1.3	n/a	chrI 5,721,019	lim-7 encodes a LIM homeodomain protein; a lim-7 mutation can result in lethality or sterility; lim-7 reporter fusion are specifically expressed in the somatic gonadal sheath cells during the L4 larval stage and continuing through adulthood.
9	tab-1	F31E8.3	n/a	chrII 6,804,197	tab-1 encodes a homeodomain protein homologous to Drosophila bsh (brain-specific homeodomain protein) and the vertebrate BarH-like homeodomain protein 1; TAB-1 is required, during early larval development, for backward movement in response to anterior touch with a wire, while during later larval stages, TAB-1 is required for response to gentle touch with a hair; TAB-1 expression begins in the early embryo in approximately 20-30 cells and is then restricted to a subset of neurons including AIB, AVJ, and RIV; TAB-1 expression in AIB may be controlled by the UNC-42 homeodomain protein and TAB-1 may autoregulate in the AVJ and RIV neurons.
10	F47D12.5	F47D12.5	n/a	chrIII 6,283,998	contains similarity to Homo sapiens Isoform 1 of Protein zyg-11 homolog B; ENSEMBL:ENSP00000294353
11	M03F8.6	M03F8.6	n/a	chrV 5,954,355	contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
12	F38A5.7	F38A5.7	n/a	chrIV 6,602,016
13	vab-7	M142.4	n/a	chrIII 10,923,070	The vab-7 gene encodes an even-skipped-like homeodomain protein that is required for DB motoneuron identity and posterior DB axonal polarity.
14	nhr-127	T13F3.3	n/a	chrV 16,263,066	nhr-127 encodes a member of the nuclear hormone receptor family; expressed in hypodermal seam cells from the embryonic 1.5-fold stage until the L1 larval stage.
15	let-381	F26B1.7	n/a	chrI 6,322,210	let-381 encodes a forkhead transcription factor and was identified in a screen for essential genes; let-381 is essential for development at different times as mutants exhibit embryonic and early larval lethality, with a few developing to sterile adults; inactivation of let-381 using RNA interference results in adults with mesodermal cell lineage defects and a reduced number of coelomocytes; reporter-gene assays indicate LET-318 is expressed when the embryo starts to elongate and continues to be expressed through all larval stages and into the adult.
16	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
17	col-121	F56D5.1	n/a	chrIV 9,395,553	col-121 encodes a cuticle collagen required for resistance to the endocrine disrupting chemical bisphenol A (BPA); col-121(nx3) and col-121(RNAi) animals are hypersensitive to BPA, but are otherwise wild-type (e.g., they have normal body shape); BPA hypersensitivity has also been observed for dpy-2(e8), dpy-7(e88) and dpy-10(e128) mutants.
18	W04H10.2	W04H10.2	n/a	chrII 606,109
19	R07C3.7	R07C3.7	n/a	chrII 916,765
20	Y116A8B.1	Y116A8B.1	n/a	chrIV 17,216,790	contains similarity to Oryza sativa P0660F12.13 protein (P0614D08.10 protein).; TR:Q94CR6
21	srh-50	C10G11.2	n/a	chrI 6,303,370	C. elegans SRH-50 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	F55C9.3	F55C9.3	n/a	chrV 19,287,274	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
23	dgn-2	F56C3.6	n/a	chrX 1,366,491	C. elegans DGN-2 protein ;
24	C54E4.4	C54E4.4	n/a	chrIV 2,163,172
25	col-105	F58F6.2	n/a	chrIV 1,358,519	C. elegans COL-105 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
26	F28B3.4	F28B3.4	n/a	chrI 4,937,314	contains similarity to Pfam domain PF06464 DMAP1-binding Domain contains similarity to Interpro domains IPR010506 (DMAP1-binding), IPR005398 (Tubby, N-terminal)
27	T05A7.3	T05A7.3	n/a	chrII 4,676,002	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
28	sdz-19	F45E6.6	n/a	chrX 12,502,884	C. elegans SDZ-19 protein ;
29	nhr-157	C17E7.5	n/a	chrV 3,867,765	C. elegans NHR-157 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	dyf-8	C43C3.3	n/a	chrX 9,700,112	dyf-8 encodes a protein predicted to form a cell-surface ligand with a zona pellucida domain; DYF-8 is required for permeability of amphid and phasmid neurons to external dyes, chemotaxis to ammonium chloride, avoidance of high osmotic stimuli, male mating, and dauer formation.
31	Y116A8C.43	Y116A8C.43	n/a	chrIV 17,089,705	contains similarity to Bacillus thuringiensis Pesticidial crystal protein cry12Aa (Insecticidal delta-endotoxinsCryXIIA(a)) (Crystaline entomocidal protoxin) (142 kDa crystalsprotein).; SW:CCAA_BACTU
32	F55F1.2	F55F1.2	n/a	chrX 2,769,819
33	F58E1.11	F58E1.11	n/a	chrII 1,692,234	contains similarity to Interpro domain IPR002034 (Alpha-isopropylmalate/homocitrate synthase, conserved site)
34	srh-192	ZC132.7	n/a	chrV 4,313,561	C. elegans SRH-192 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	AH10.3	AH10.3	n/a	chrV 14,144,698	contains similarity to Tomato yellow leaf curl virus Hypothetical 10.9 kDa protein (C4 protein).; SW:YC4_TYLCU
36	Y65A5A.3	Y65A5A.3	n/a	chrIV 16,416,285	contains similarity to Human papillomavirus type 13 Probable E4 protein.; SW:VE4_HPV13
37	T25B6.3	T25B6.3	n/a	chrX 9,027,882
38	gpc-2	F08B6.2	n/a	chrI 6,757,967	gpc-2 encodes one of two C. elegans heterotrimeric G protein gamma subunits; gpc-2 is required, along with its partner GPB-1, a G protein beta subunit, for proper mitotic spindle positioning and orientation during early embryonic cell divisions; to date, GPC-2 expression has been reported in electrically excitable cells (all neurons and muscles).
39	str-118	F57A8.3	n/a	chrV 10,052,955	C. elegans STR-118 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	srj-37	F48G7.1	n/a	chrV 639,279	C. elegans SRJ-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	K12B6.7	K12B6.7	n/a	chrV 6,297,759
42	W06B11.1	W06B11.1	n/a	chrX 5,850,462	contains similarity to Pfam domain PF05301 Protein of unknown function (DUF738) contains similarity to Interpro domain IPR007965 (Protein of unknown function DUF738)
43	F46C8.3	F46C8.3	n/a	chrX 7,526,360
44	F42H10.2	F42H10.2	n/a	chrIII 8,490,759	contains similarity to Pfam domain PF06747 CHCH domain contains similarity to Interpro domains IPR010625 (CHCH), IPR013032 (EGF-like region, conserved site)
45	C55A1.9	C55A1.9	n/a	chrV 15,626,819	contains similarity to Interpro domain IPR000694 (Proline-rich region)
46	R13D11.3	R13D11.3	n/a	chrV 815,301	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	srt-12	E03D2.4	n/a	chrV 4,241,727	C. elegans SRT-12 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
48	flnb-1	C23F12.2	n/a	chrX 9,402,619	C. elegans FLNB-1 protein; contains similarity to Pfam domains PF00630 (Filamin/ABP280 repeat) (2), PF00307 (Calponin homology (CH) domain) (3)contains similarity to Interpro domains IPR001298 (Filamin/ABP280 repeat), IPR014756 (Immunoglobulin E-set), IPR013783 (Immunoglobulin-like fold), IPR000694 (Proline-rich region), IPR016146 (Calponin-homology), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR001715 (Calponin-like actin-binding)
49	dpy-28	Y39A1B.3	n/a	chrIII 10,770,127	dpy-28 encodes a non-SMC condensin subunit homolog, similar to XCAP-D2 in Xenopus, Cnd1 in S. pombe, and Ycs4p in S. cerevisiae, that is required for negative, chromosome-wide regulation of X-chromosomal genes in XX but not XO animals (dosage compensation), and for some undetermined aspect of body morphogenesis; DPY-28 is part of a multiprotein 'dosage compensation' complex with DPY-26, DPY-27 and MIX-1.
50	F08B6.3	F08B6.3	n/a	chrI 6,759,203	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR000886 (Endoplasmic reticulum, targeting sequence)