UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nlp-39	C54C8.9	5e-33	chrI 12,461,774	C. elegans NLP-39 protein ;
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F07C4.6	F07C4.6	n/a	chrV 7,627,266	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
4	col-116	F17E9.1	n/a	chrIV 8,357,297	C. elegans COL-116 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
5	col-102	C18H7.3	n/a	chrIV 605,160	col-102 encodes a cuticle collagen.
6	F43H9.4	F43H9.4	n/a	chrV 8,027,713	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
7	col-35	C15A11.1	n/a	chrI 7,386,359	col-35 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens; the amino- and carboxyl-terminal cysteine-rich regions of COL-35 are most closely related to those of COL-8, COL-19, and COL-39.
8	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
9	T01C3.4	T01C3.4	n/a	chrV 14,994,531	contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
10	scl-2	F49E11.10	n/a	chrIV 13,058,350	C. elegans SCL-2 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
11	col-183	F02D10.1	n/a	chrX 13,467,159	C. elegans COL-183 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
12	C32F10.4	C32F10.4	n/a	chrI 5,809,249
13	W01F3.2	W01F3.2	n/a	chrV 20,656,586	contains similarity to Interpro domain IPR000585 (Hemopexin)
14	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	C03G6.6	C03G6.6	n/a	chrV 7,358,148	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
16	F49H6.5	F49H6.5	n/a	chrV 17,024,380	The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
17	clec-97	ZK39.6	n/a	chrI 11,153,502	C. elegans CLEC-97 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
18	F11F1.6	F11F1.6	n/a	chrIII 13,403,684	contains similarity to Escherichia coli Shiga toxin 1 B subunit.; TR:Q8L167
19	grl-19	R02D3.6	n/a	chrIV 252,252	grl-19 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-19 is expressed in intestine; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
20	thn-2	F28D1.5	n/a	chrIV 12,383,557	C. elegans THN-2 protein; contains similarity to Pfam domain PF00314 Thaumatin family contains similarity to Interpro domain IPR001938 (Thaumatin, pathogenesis-related)
21	grl-17	C56A3.1	n/a	chrV 13,562,991	grl-17 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-17 is expressed in pharynx, rectal epithelium, amphid socket cells, larval arcade cells, and larval hypodermis; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
22	col-40	T13B5.4	n/a	chrII 1,105,772	col-40 encodes a cuticle collagen protein that belongs to the col-6 cuticle collagen family; col-40 transcript is present in L1 larvae and at the L2d-dauer molt.
23	clec-98	ZK39.7	n/a	chrI 11,154,783	C. elegans CLEC-98 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
24	F47B8.8	F47B8.8	n/a	chrV 14,332,167	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domain IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal)
25	ttr-2	K03H1.4	n/a	chrIII 9,928,259	K03H1.4 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of K03H1.4 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
26	nlp-32	F30H5.2	n/a	chrIII 486,349	C. elegans NLP-32 protein; contains similarity to Interpro domain IPR002952 (Eggshell protein)
27	C06G3.3	C06G3.3	n/a	chrIV 7,036,272
28	F07C3.9	F07C3.9	n/a	chrV 9,254,456
29	ins-23	M04D8.3	n/a	chrIII 10,028,305	ins-23 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-23 is one of 38 insulin-like peptides in C. elegans, and is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral nerve cord neurons; as loss of INS-23 function via RNA-mediated interference does not results in any abnormalities, the precise role of INS-23 in C. elegans development is not yet clear.
30	col-158	D2023.7	n/a	chrV 11,830,378	C. elegans COL-158 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
31	F56H9.2	F56H9.2	n/a	chrV 12,637,872	contains similarity to Plasmodium falciparum Transport protein, putative.; TR:Q8IHR3
32	C13A2.6	C13A2.6	n/a	chrV 7,271,247	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
33	F17C11.4	F17C11.4	n/a	chrV 10,952,702	contains similarity to Mus musculus Desmoglein 2 precursor.; SW:DSG2_MOUSE
34	clec-60	ZK666.6	n/a	chrII 10,480,905	clec-60 encodes a C-type lectin protein with no obvious non-nematode orthologs required for normal resistance to infection with Microbacterium nematophilum; clec-60 transcription is induced 6.6-fold by infection with M. nematophilum, making it one of the most strongly infection-responsive genes (second only to tts-1), while not being induced by other pathogens; CLEC-60 is expressed throughout the larval intestine, continuing adult expression primarily in the posterior intestinal cells int8 and int9; CLEC-60 contains an N-terminal von Willebrand factor type A domain and a C-terminal C-type lectin domain; CLEC-60 has no obvious function in mass RNAi assays, and is dispensable for viability.
35	col-2	W01B6.7	n/a	chrIV 10,084,918	col-2 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies); expression peaks during the molt that separates the L2 larval and dauer stages as the dauer cuticle is being formed, and mRNA is expressed at low levels in post-dauer L4 larvae and in adult animals.
36	C13A2.3	C13A2.3	n/a	chrV 7,283,523	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
37	C50F4.8	C50F4.8	n/a	chrV 9,518,171
38	F57F4.2	F57F4.2	n/a	chrV 6,388,125	contains similarity to Felis silvestris catus RPGR (Fragment).; TR:Q56PC0
39	clec-1	F25B4.9	n/a	chrV 5,700,529	C. elegans CLEC-1 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
40	F40G12.5	F40G12.5	n/a	chrV 14,269,931	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
41	C18A11.1	C18A11.1	n/a	chrX 8,069,882
42	ncx-9	C13D9.8	n/a	chrV 4,993,269	ncx-9 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6/-8 and NCX-10; NCX-9 may function intracellularly; NCX-9 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-9 has no obvious function in mass RNAi assays.
43	W03D2.6	W03D2.6	n/a	chrIV 4,057,478
44	F53A9.8	F53A9.8	n/a	chrX 8,718,676	contains similarity to Plasmodium chabaudi Pc-fam-3 protein putative (Fragment).; TR:Q4XGP3
45	C35C5.9	C35C5.9	n/a	chrX 11,536,770	contains similarity to Haemophilus influenzae Monofunctional biosynthetic peptidoglycan transglycosylases(EC 2.4.2.-) (Monofunctional TGase).; SW:MTGA_HAEIN
46	F58H7.5	F58H7.5	n/a	chrIV 920,399
47	B0507.8	B0507.8	n/a	chrV 8,761,695	contains similarity to Schizosaccharomyces pombe Nucleoporin nup211 (Nuclear pore protein nup211).; SW:O74424
48	inx-16	R12E2.5	n/a	chrI 4,163,537	inx-16 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; as loss of INX-16 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of INX-16 in C. elegans development and/or behavior is not yet known; the INX-16 expression pattern has not been determined.
49	F48G7.2	F48G7.2	n/a	chrV 637,034
50	ptr-16	T21H3.2	n/a	chrV 1,172,902	ptr-16 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-16 is partially required for normal molting from L2 to L3 larval stages; however, PTR-16 and PTR-1 together are strongly required for both molting and viability, with double ptr-1/-16 RNAi animals showing pronounced molting defects and lethality; PTR-16 is also required for normal growth to full size and locomotion.