UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	lys-9	C54C8.6	5e-96	chrI 12,455,280	C. elegans LYS-9 protein; contains similarity to Interpro domain IPR017853 (Glycoside hydrolase, catalytic core)
2	pld-1	C04G6.3	n/a	chrII 5,087,755	C. elegans PLD-1 protein; contains similarity to Pfam domains PF00169 (PH domain) , PF00614 (Phospholipase D Active site motif) (2), PF00787 (PX domain) contains similarity to Interpro domains IPR016555 (Phospholipase D, eukaryota), IPR001683 (Phox-like), IPR001849 (Pleckstrin-like), IPR001736 (Phospholipase D/Transphosphatidylase), IPR015679 (Phospholipase D)
3	cdc-6	C43E11.10	n/a	chrI 4,269,180	cdc-6 encodes a homolog of an origin complex component (CDC6) which in yeast controls the start of DNA replication, and also has a distant paralog (Y39A1A.12) within the C. elegans genome; CDC-6 is superficially dispensable for embryonic viability, perhaps because of redundancy with Y39A1A.12.
4	F43C1.3	F43C1.3	n/a	chrIII 4,244,006	F43C1.3 encodes a protein containing an HIT-type zinc finger domain and a coiled-coil region; loss of F43C1.3 activity via RNAi results in slower than normal growth rates.
5	F59A1.13	F59A1.13	n/a	chrV 17,689,072	contains similarity to Pfam domains PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin) , PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF02377 (Dishevelled specific domain) contains similarity to Interpro domains IPR003351 (Dishevelled protein), IPR011991 (Winged helix repressor DNA-binding), IPR001478 (PDZ/DHR/GLGF), IPR015506 (Dishevelled related protein), IPR008339 (Dishevelled region), IPR000591 (Pleckstrin/ G-protein, interacting region)
6	W06D11.3	W06D11.3	n/a	chrX 12,299,278	contains similarity to Saccharomyces cerevisiae Involved in maintaining genome stability. Homologous to E. coli RecQ and human BLM and WRN proteins that are defective in the cancer-prone disorder Bloom's syndrome and the premature aging disorder Werner's syndrome, respectively; SGD:YMR190C
7	fbxa-184	F45C12.8	n/a	chrII 1,710,841	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
8	srh-187	F10G2.8	n/a	chrV 7,339,214	C. elegans SRH-187 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	Y43E12A.3	Y43E12A.3	n/a	chrIV 10,988,514	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
10	thoc-3	F32H2.4	n/a	chrI 8,972,046	C. elegans THOC-3 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
11	F23F1.6	F23F1.6	n/a	chrII 36,279	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR004755 (Cationic amino acid transport permease), IPR004841 (Amino acid permease-associated region), IPR002293 (Amino acid/polyamine transporter I)
12	T10B11.2	T10B11.2	n/a	chrI 6,934,027	contains similarity to Pfam domain PF00781 Diacylglycerol kinase catalytic domain (presumed) contains similarity to Interpro domain IPR001206 (Diacylglycerol kinase, catalytic region)
13	wrt-7	ZK1037.10	n/a	chrV 15,336,119	wrt-7 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a Wart domain, and a Hint/Hog domain; the Hint/Hog domain is predicted to cut WRT-7 into two halves and then covalently link cholesterol to the C-terminus of the Wart domain; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-7 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
14	F14H12.8	F14H12.8	n/a	chrX 4,363,765
15	F29C4.4	F29C4.4	n/a	chrIV 111,769
16	C54G4.9	C54G4.9	n/a	chrI 8,025,714	contains similarity to Pyrococcus furiosus Hypothetical protein PF0537.; TR:Q8U3D2
17	sru-48	T03G11.2	n/a	chrX 5,180,802	C. elegans SRU-48 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
18	gop-2	C34E10.2	n/a	chrIII 5,259,723	gop-2 encodes a member of the conserved hypothetical ATP binding protein family that affects embryonic viability, growth, and fertility.
19	snx-3	W06D4.5	n/a	chrI 9,064,058	C. elegans SNX-3 protein; contains similarity to Pfam domain PF00787 PX domain contains similarity to Interpro domain IPR001683 (Phox-like)
20	mdt-4	ZK546.13	n/a	chrII 4,943,020	C. elegans MDT-4 protein ; contains similarity to Drosophila melanogaster Flybase gene name is MED4-PA;; FLYBASE:CG8609
21	fkh-4	C29F7.5	n/a	chrX 13,429,320	fkh-4 encodes a member of the forkhead domain transcription factor family.
22	T19D2.3	T19D2.3	n/a	chrX 3,939,726
23	T04D3.1	T04D3.1	n/a	chrI 13,303,528	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
24	C18A3.1	C18A3.1	n/a	chrII 5,720,938	contains similarity to Pfam domain PF05063 MT-A70 contains similarity to Interpro domains IPR007757 (MT-A70), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
25	sgo-1	C33H5.15	n/a	chrIV 7,795,579	C. elegans SGO-1 protein; contains similarity to Pfam domain PF07557 Shugoshin C terminus contains similarity to Interpro domain IPR011515 (Shugoshin, C-terminal)
26	aat-8	F28F9.4	n/a	chrIV 3,863,573	aat-8 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-8 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-8 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
27	ZC443.1	ZC443.1	n/a	chrV 12,809,256	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
28	W05H12.2	W05H12.2	n/a	chrI 13,412,326	contains similarity to Pfam domain PF01612 3'-5' exonuclease contains similarity to Interpro domains IPR002562 (3'-5' exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
29	F02H6.4	F02H6.4	n/a	chrIV 14,217,678	contains similarity to Saccharomyces cerevisiae GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2; SGD:YAL035W
30	cyp-25A4	C36A4.6	n/a	chrIII 3,850,968	C. elegans CYP-25A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
31	K06B9.2	K06B9.2	n/a	chrIV 4,192,443	K06B9.2 encodes a putative UDP-N-acetylglucosamine pyrophosphorylase, paralogous to C36A4.4 and orthologous to human UAP1 (OMIM:602862) and UAP1L1; K06B9.2 is thought to catalyse the fourth step of the hexosamine pathway to UDP-N-acetylglucosamine or UDP-N-acetylgalactosamine; K06B9.2 transcripts are enriched during oogenesis; K06B9.2(RNAi) animals have an osmotically-sensitive embryonic lethal phenotype, presumably because of defects in chitin and eggshell synthesis.
32	nspb-4	F38A5.10	n/a	chrIV 6,598,366	C. elegans NSPB-4 protein; contains similarity to Pfam domain PF07312 Protein of unknown function (DUF1459) contains similarity to Interpro domain IPR009924 (Protein of unknown function DUF1459)
33	F02E8.4	F02E8.4	n/a	chrX 4,455,689
34	acbp-5	T12D8.3	n/a	chrIII 13,640,695	C. elegans ACBP-5 protein; contains similarity to Pfam domains PF00023 (Ankyrin repeat) (2), PF00887 (Acyl CoA binding protein) contains similarity to Interpro domains IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR002110 (Ankyrin), IPR000582 (Acyl-CoA-binding protein, ACBP)
35	vps-26	T20D3.7	n/a	chrIV 9,340,583	C. elegans VPS-26 protein; contains similarity to Pfam domain PF03643 Vacuolar protein sorting-associated protein 26 contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR005377 (Vacuolar protein sorting-associated protein 26)
36	C09F5.3	C09F5.3	n/a	chrIII 664,551	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
37	C13F10.6	C13F10.6	n/a	chrV 7,220,078
38	pes-23	F14B8.3	n/a	chrX 6,902,654	C. elegans PES-23 protein; contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
39	math-36	R52.8	n/a	chrII 2,118,724	C. elegans MATH-36 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
40	str-5	T23D5.12	n/a	chrV 15,753,810	C. elegans STR-5 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
41	set-4	C32D5.5	n/a	chrII 6,330,534	set-4 encodes a putative histone H4 lysine-20 methyltransferase; SET-4 is orthologous to Drosophila SUV4-20, and to human SUV420H1 (OMIM:610881) and SUV420H2; neither set-4(n4600) nor set-4(RNAi) have any obvious phenotypes.
42	tag-319	C30B5.1	n/a	chrII 6,200,135	C. elegans TAG-319 protein ;
43	F52G3.3	F52G3.3	n/a	chrX 16,946,368	contains similarity to Medicago truncatula Putative uncharacterized protein.; TR:A2Q378
44	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
45	set-14	R06F6.4	n/a	chrII 10,794,856	set-14 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-14 is paralogous to SET-10, SET-18, and SET-30; SET-14 has no obvious function in individual RNAi assays of vulval development, or in mass RNAi assays.
46	C09G9.7	C09G9.7	n/a	chrIV 8,878,734	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
47	duo-1	F38B7.5	n/a	chrV 11,556,440	C. elegans DUO-1 protein; contains similarity to Pfam domains PF00443 (Ubiquitin carboxyl-terminal hydrolase) , PF02338 (OTU-like cysteine protease) contains similarity to Interpro domains IPR003323 (Ovarian tumour, otubain), IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
48	srx-65	K07C6.8	n/a	chrV 3,922,434	C. elegans SRX-65 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
49	T09B4.1	T09B4.1	n/a	chrI 6,186,762	contains similarity to Pfam domain PF04188 Mannosyltransferase (PIG-V)) contains similarity to Interpro domain IPR007315 (Mannosyltransferase, PIG-V)
50	T09E11.4	T09E11.4	n/a	chrI 12,361,669	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)