UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C53C11.1	C53C11.1	6e-143	chrX 17,340,978	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
2	syn-13	F36F2.4	n/a	chrI 9,003,016	C. elegans SYN-13 protein; contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR010989 (t-SNARE), IPR006011 (Syntaxin, N-terminal), IPR000727 (Target SNARE coiled-coil region), IPR006012 (Syntaxin/epimorphin, conserved site)
3	cah-5	R173.1	n/a	chrX 7,021,932	cah-5 encodes a member of the carbonic anhydrase family.
4	F44F1.4	F44F1.4	n/a	chrI 13,264,689	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
5	tor-2	Y37A1B.13	n/a	chrIV 13,983,393	tor-2 encodes a AAA ATPase that, along with TOR-1 and OOC-5, comprise the three C. elegans orthologs of human torsinA, mutations in which are associated with torsion dystonia (OMIM:605204); overexpression of TOR-2 in nematodes with polyglutamine repeat-induced protein aggregates indicates that TOR-2 can suppress protein aggregation, suggesting TOR-2 may play a role in regulation of protein folding; in wild-type animals, TOR-2 localizes to the endoplasmic reticulum; in animals containing polyglutamine protein aggregates, TOR-2 localizes to these sites of protein aggregation.
6	Y47H9C.7	Y47H9C.7	n/a	chrI 11,892,653	Y47H9C.7 is orthologous to the human gene EUKARYOTIC TRANSLATION INITIATION FACTOR 2B, SUBUNIT 2 (BETA, 39KD) (EIF2B2; OMIM:606454), which when mutated leads to disease.
7	Y38H6C.14	Y38H6C.14	n/a	chrV 20,527,484	contains similarity to Leishmania major strain Friedlin Proteophosphoglycan 5.; TR:Q4FX62
8	srh-269	T03E6.5	n/a	chrV 16,591,043	C. elegans SRH-269 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	gpa-4	T07A9.7	n/a	chrIV 403,531	gpa-4 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASI.
10	cdh-1	R10F2.1	n/a	chrIII 2,923,253	cdh-1 encodes a cadherin that is similar, in the extracellular domain, to the Drosophila cadherin Dachsous (Ds); although the precise role of cdh-1 in C. elegans development and/or behavior is not yet known, loss of cdh-1 activity via RNAi using the hypersensitive rrf-3 strain can result in locomotion and growth defects, as well as larval lethality.
11	C52E12.4	C52E12.4	n/a	chrII 7,017,594	contains similarity to Pfam domains PF01477 (PLAT/LH2 domain) , PF02141 (DENN (AEX-3) domain) , PF03456 (uDENN domain) , PF03455 (dDENN domain) , PF02759 (RUN domain) contains similarity to Interpro domains IPR005112 (dDENN), IPR001024 (Lipoxygenase, LH2), IPR008976 (Lipase/lipooxygenase, PLAT/LH2), IPR004012 (RUN), IPR005113 (uDENN), IPR001194 (DENN)
12	fbxb-79	R07H5.7	n/a	chrIV 11,189,235	C. elegans FBXB-79 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
13	ccb-2	W10C8.1	n/a	chrI 2,848,257	C. elegans CCB-2 protein; contains similarity to Pfam domains PF00774 (Dihydropyridine sensitive L-type calcium channel (Beta subunit)) (2), PF00018 (SH3 domain) contains similarity to Interpro domains IPR000584 (Voltage-dependent calcium channel, L-type, beta subunit), IPR001452 (Src homology-3)
14	srx-121	C04E12.8	n/a	chrV 3,371,855	C. elegans SRX-121 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
15	sra-31	C56C10.5	n/a	chrII 6,577,792	C. elegans SRA-31 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
16	F31D5.1	F31D5.1	n/a	chrII 4,220,835	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR003976 (Potassium channel, two pore-domain, TREK), IPR016196 (MFS general substrate transporter)
17	F08D12.7	F08D12.7	n/a	chrII 2,768,193	F08D12.7 encodes a novel protein conserved amongst Caenorhaditis species; although loss of F08D12.7 activity via RNAi results in no obvious defects, F08D12.7 transcripts are enriched in L1-stage muscle and upregulated in L2 larvae in response to overexpression of hlh-2 and hlh-8; in addition, in analyses of the early embryonic transcriptome, F08D12.7 transcripts are classified as strictly maternal; an F08D12.7::gfp reporter fusion is expressed in the vm1 and vm2 vulval muscles, the intestinal and anal depressor muscles, the hypodermis, distal tip cell, ventral nerve cord, head and tail neurons, and body wall muscle.
18	F53A2.3	F53A2.3	n/a	chrIII 13,338,285	contains similarity to Streptococcus agalactiae Hypothetical protein.; TR:Q8E5X9
19	F11A5.6	F11A5.6	n/a	chrV 16,203,986	contains similarity to Bradyrhizobium japonicum Bll7368 protein.; TR:Q89DS1
20	C11D2.2	C11D2.2	n/a	chrIV 6,187,162	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001461 (Peptidase A1)
21	srbc-63	T06E6.11	n/a	chrV 15,412,055	C. elegans SRBC-63 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
22	Y116A8C.25	Y116A8C.25	n/a	chrIV 17,076,616	contains similarity to Pfam domain PF03881 Fructosamine kinase contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR005581 (Fructosamine kinase)
23	itsn-1	Y116A8C.36	n/a	chrIV 17,122,917	tag-11/Y116A8C.36 encodes a homolog of human NCF1, which when mutated leads to chronic granulomatous disease (OMIM:306400).
24	F48A11.4	F48A11.4	n/a	chrII 214,905
25	T05G5.4	T05G5.4	n/a	chrIII 9,749,322	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000290632
26	F55A4.1	F55A4.1	n/a	chrX 1,036,270	contains similarity to Pfam domain PF00957 Synaptobrevin contains similarity to Interpro domains IPR010908 (Longin), IPR011012 (Longin-like), IPR001388 (Synaptobrevin)
27	R01H2.1	R01H2.1	n/a	chrIII 7,062,968
28	Y37E11B.6	Y37E11B.6	n/a	chrIV 3,598,943	Y37E11B.6 encodes an ortholog of Rpp21 (Rpr2), a protein subunit of the endoribonuclease RNAse P, which cleaves tRNA precursors to produce their mature 5' end.
29	pfd-5	R151.9	n/a	chrIII 7,198,447	pfd-5 encodes a putative prefoldin 5 subunit, orthologous to human PFDN5 (OMIM:604899), that is required for normal microtubule growth, embryonic and larval viability, fertility, vulval development, and locomotion; PFD-5 is expressed in most, if not all, tissues; pfd-5(RNAi) animals show sterile progeny, larval arrest or lethality, uncoordination, and abnormal body shapes, and pfd-5(RNAi) embryos show a reduced microtubule growth rate.
30	F40G12.6	F40G12.6	n/a	chrV 14,272,120	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
31	F01G12.1	F01G12.1	n/a	chrX 16,395,930	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
32	srh-8	K09D9.8	n/a	chrV 4,006,527	C. elegans SRH-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR005394 (P2Y12 purinoceptor)
33	srd-29	F07C4.3	n/a	chrV 7,636,306	C. elegans SRD-29 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	K02D7.2	K02D7.2	n/a	chrIV 312,624	K02D7.2 encodes an ortholog of human SNAI2/SLUG (OMIM:602150, mutated in Waardenburg syndrome type IID) and Drosophila ESCARGOT; based on its orthology to SNAI2, K02D7.2 is predicted to be a transcriptional inhibitor.
35	T17A3.9	T17A3.9	n/a	chrIII 152,890
36	rap-1	C27B7.8	n/a	chrIV 8,917,869	rap-1 encodes a member of the Ras superfamily of small GTPases; the activated protein interacts with W05B10.4 and T14G10.2 in yeast two-hybrid assays and rap-1 is expressed in some neurons in the head and tail, the rectal epithelial cells, body muscle, hypodermis, and in the somatic cells of the gonad.
37	Y54G11A.11	Y54G11A.11	n/a	chrII 14,350,230	contains similarity to Pfam domain PF05129 Transcription elongation factor Elf1 like contains similarity to Interpro domain IPR007808 (Protein of unknown function DUF701, zinc-binding putative)
38	C14E2.1	C14E2.1	n/a	chrX 1,826,905
39	Y39A1A.20	Y39A1A.20	n/a	chrIII 10,699,807
40	M01B2.10	M01B2.10	n/a	chrV 15,261,657	contains similarity to Homo sapiens Phytanoyl-CoA 2-hydroxylase-interacting protein-like; ENSEMBL:ENSP00000362987
41	K09F5.4	K09F5.4	n/a	chrX 7,710,385
42	T13C5.6	T13C5.6	n/a	chrX 6,207,063	contains similarity to Pfam domain PF01569 PAP2 superfamily contains similarity to Interpro domains IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase), IPR016118 (Phosphatidic acid phosphatase/chloroperoxidase, N-terminal)
43	srh-270	F37B4.5	n/a	chrV 2,860,866	C. elegans SRH-270 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	ugt-10	T19H12.11	n/a	chrV 4,899,135	C. elegans UGT-10 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
45	C14B1.5	C14B1.5	n/a	chrIII 3,708,022	C14B1.5 encodes an ortholog of S. cerevisiae YIL103 and human DPH2L1/OVCA1 (OMIM:603527, deleted or downregulated in ovarian tumors); C14B1.5 is paralogous to S. cerevisiae DPH2/YKL191W, a protein component of diphtamide synthesis; C14B1.5 has no obvious function in mass RNAi assays.
46	rod-1	F55G1.4	n/a	chrIV 7,481,969	C. elegans ROD-1 protein ; contains similarity to Caenorhabditis remanei Putative RoughDeal (Fragment).; TR:Q4TTM7
47	tgt-1	ZK829.6	n/a	chrIV 11,958,629	tgt-1 encodes a tRNA-guanine transglycosylase predicted to be mitochondrial.
48	tag-143	ZK856.9	n/a	chrV 10,211,282	C. elegans TAG-143 protein; contains similarity to Pfam domain PF04438 HIT zinc finger contains similarity to Interpro domain IPR007529 (Zinc finger, HIT-type)
49	F45G2.9	F45G2.9	n/a	chrIII 13,436,244	contains similarity to Pfam domain PF01728 FtsJ-like methyltransferase contains similarity to Interpro domains IPR016448 (23S ribosomal RNA methyltransferase), IPR015507 (Ribosomal RNA methyltransferase J), IPR002877 (Ribosomal RNA methyltransferase RrmJ/FtsJ)
50	T13C5.4	T13C5.4	n/a	chrX 6,192,236	T13C5.4 encodes a paired-like homeodomain protein of the Q50 class, which has no obvious function in mass RNAi assays.