UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C50H11.8	C50H11.8	3e-52	chrV 3,055,230
2	acr-23	F59B1.9	n/a	chrV 3,655,579	acr-23 encodes an alpha 7-like homomer-forming subunit of the nicotinic acetylcholine receptor (nAChR) superfamily which encode ligand-gated ion channels that regulate fast action of acetylcholine at neuromuscular junctions and in the nervous system; ACR-23 is a member of the DEG-3-like group of nAChR subunits which appears to be unique to nematodes.
3	T28F4.6	T28F4.6	n/a	chrI 7,493,740	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
4	F16H6.4	F16H6.4	n/a	chrV 18,199,789	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
5	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
6	srj-39	F38H12.1	n/a	chrV 4,105,406	C. elegans SRJ-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	C40H5.3	C40H5.3	n/a	chrX 11,760,088	contains similarity to Solanum aggregatum NADH dehydrogenase subunit (Fragment).; TR:Q8HSG2
8	T23F6.1	T23F6.1	n/a	chrIV 12,720,397	contains similarity to Interpro domain IPR002952 (Eggshell protein)
9	nhr-272	T07C5.2	n/a	chrX 12,704,012	C. elegans NHR-272 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
10	T21C9.9	T21C9.9	n/a	chrV 10,591,537	contains similarity to Interpro domain IPR000694 (Proline-rich region)
11	F53C11.3	F53C11.3	n/a	chrV 13,783,418	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR000507 (Adrenergic receptor, beta 1), IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
12	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
13	nhr-15	F33E11.1	n/a	chrV 321,993	nhr-15 is predicted to encode a member of the nuclear hormone receptor family.
14	odd-1	B0280.4	n/a	chrIII 7,108,745	odd-1 encodes a C2H2-type zinc finger-containing transcription factor similar to Drosophila odd skipped which is required for embryonic patterning; ODD-1 is expressed in the gut during embryogenesis and appears to be essential for larval development.
15	str-90	F58G4.2	n/a	chrV 8,105,065	C. elegans STR-90 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	fbxa-102	K03D7.7	n/a	chrV 17,492,710	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
17	T07H6.5	T07H6.5	n/a	chrX 6,288,966	contains similarity to Pfam domain PF00084 Sushi domain (SCR repeat) contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
18	D2005.3	D2005.3	n/a	chrI 7,814,395	contains similarity to Pfam domain PF01984 Double-stranded DNA-binding domain contains similarity to Interpro domain IPR002836 (DNA-binding TFAR19-related protein)
19	F42G2.3	F42G2.3	n/a	chrII 2,420,134
20	srh-277	K05D4.6	n/a	chrV 16,186,134	C. elegans SRH-277 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001280 (Photosystem I psaA and psaB)
21	gpb-2	F52A8.2	n/a	chrI 7,319,690	gpb-2 encodes an ortholog of Gbeta(5), that is dispensable for viability, but required for normal egg-laying, locomotion, and pharyngeal pumping; GBP-2 may regulate the interaction between the GOA-1 and EGL-30 signaling pathways based on genetic analysis; gpb-2 is expressed throughout development in the nervous system and in muscle, and expression is dependent upon expression of both EAT-16 and EGL-10.
22	C08F11.7	C08F11.7	n/a	chrIV 13,637,874	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR002398 (Peptidase C14, caspase precursor p45)
23	C16D9.4	C16D9.4	n/a	chrV 8,241,945	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domains IPR008068 (Cytochrome P450, E-class, group I, CYP2B-like), IPR012444 (Protein of unknown function DUF1647)
24	Y38H6C.13	Y38H6C.13	n/a	chrV 20,523,455	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
25	T26C11.2	T26C11.2	n/a	chrX 1,836,847	contains similarity to Interpro domains IPR000893 (Luteovirus ORF6 protein), IPR000694 (Proline-rich region), IPR000480 (Glutelin)
26	C18B2.6	C18B2.6	n/a	chrX 3,615,375	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
27	K10D11.3	K10D11.3	n/a	chrIV 12,984,093	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
28	gpdh-1	F47G4.3	n/a	chrI 14,077,014	gpdh-1 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-1 activity via large-scale RNAi screens results in no obvious defects, gpdh-1 mRNA expression is upregulated in response to hypertonicity, suggesting that GPDH-1 does play a role in osmotic stress adaptation in C. elegans.
29	R07E3.2	R07E3.2	n/a	chrX 10,336,549	contains similarity to Homo sapiens MYST histone acetyltransferase 3; ENSEMBL:ENSP00000265713
30	H06O01.2	H06O01.2	n/a	chrI 7,012,174	H06O01.2 encodes a large (1,461-aa) putative chromodomain helicase DNA-binding protein that inhibits DHC-1 in vivo; H06O01.2 is orthologous to budding yeast CHD1, human CHD1 (OMIM:602118), and human CHD2 (OMIM:602119); H06O01.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that H06O01.2 negatively regulates dynein; H06O01.2 has no obvious function in mass RNAi assays.
31	C29F4.3	C29F4.3	n/a	chrIV 11,222,963	contains similarity to Spodoptera litura nucleopolyhedrovirus Hypothetical protein.; TR:Q91BF2
32	ssr-2	C14A11.7	n/a	chrX 2,825,197	C. elegans SSR-2 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily)
33	wrt-3	F38E11.7	n/a	chrIV 9,476,571	wrt-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a region of low-complexity sequence; WRT-3 is expressed in the trinucleate pharyngeal gland cell g1 beginning at the three-fold stage of embryogenesis, in seam cells and hypodermis, and in single muscle cells and the distal tip cells of late stage larvae and adults; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-3 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
34	C55A6.7	C55A6.7	n/a	chrV 11,519,888	contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
35	F41G3.3	F41G3.3	n/a	chrII 6,757,638
36	C30F12.5	C30F12.5	n/a	chrI 6,995,898	contains similarity to Interpro domain IPR000694 (Proline-rich region)
37	C42C1.6	C42C1.6	n/a	chrIV 12,294,581	contains similarity to Drosophila melanogaster Flybase gene name is CG16970-PA; FLYBASE:CG16970-PA
38	srh-213	T22F3.5	n/a	chrV 3,593,857	C. elegans SRH-213 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	C33A12.1	C33A12.1	n/a	chrIV 9,524,313	C33A12.1 encodes the C. elegans ortholog of the NDUFA5/B13 subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I).
40	R09A1.3	R09A1.3	n/a	chrV 1,025,455
41	srx-64	K07C6.7	n/a	chrV 3,930,085	C. elegans SRX-64 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
42	pqn-39	F48F7.4	n/a	chrX 13,967,574	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
43	cdr-3	C54D10.2	n/a	chrV 12,416,844	C. elegans CDR-3 protein; contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR010987 (Glutathione S-transferase, C-terminal-like)
44	F45H7.1	F45H7.1	n/a	chrIII 3,346,522	contains similarity to Mus musculus Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).; SW:SPH2_MOUSE
45	Y54G9A.4	Y54G9A.4	n/a	chrII 13,714,353	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
46	C15H9.3	C15H9.3	n/a	chrX 6,116,887	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
47	cyp-14A1	K09A11.2	n/a	chrX 13,266,131	C. elegans CYP-14A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
48	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
49	ugt-25	C10H11.3	n/a	chrI 4,733,442	C. elegans UGT-25 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
50	bcc-1	M7.3	n/a	chrIV 11,089,293	bcc-1 encodes a homolog of Drosophila and vertebrate Bicaudal C (BICC) that contains KH RNA-binding domains, a serine-rich region, and a SAM (sterile alpha motif) domain; by homology, BCC-1 is predicted to function as a cytoplasmic RNA-binding protein that is required for translational regulation and/or mRNA stability during embryonic or germline development; however, as loss of bcc-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of BCC-1 in C. elegans development and/or behavior is not yet known.