UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C50F2.4	C50F2.4	2e-98	chrI 3,890,325
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	ptr-13	K07C10.1	n/a	chrII 11,159,735	ptr-13 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-13 is weakly required for normal molting from L4 to adult stages; PTR-13 is also required for normal growth to full size and locomotion.
5	nhr-178	F16B4.9	n/a	chrV 1,605,896	C. elegans NHR-178 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
6	C17E7.10	C17E7.10	n/a	chrV 3,899,486	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
7	gcy-23	T26C12.4	n/a	chrIV 3,286,107	gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, loss of gcy-23 activity via RNAi results in lifespan extension; GCY-23 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
8	srz-23	F58E2.9	n/a	chrIV 3,454,195	C. elegans SRZ-23 protein ;
9	T16G12.4	T16G12.4	n/a	chrIII 10,058,154	contains similarity to Treponema denticola FlhB.; TR:Q9APY7
10	srj-22	F28H7.1	n/a	chrV 10,743,082	C. elegans SRJ-22 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	srv-21	H04M03.8	n/a	chrIV 5,876,704	C. elegans SRV-21 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
12	Y48E1B.7	Y48E1B.7	n/a	chrII 13,580,236	Y48E1B.7 encodes a C2H2-type zinc-finger protein required for embryonic development and fertility; Y48E1B.7 transcript levels are diminished by ERI-1, RDE-3, and RRF-2, perhaps through endogenous RNAi; Y48E1B.7 is paralogous to MCD-1, but has no obvious non-nematode orthologs; Y48E1B.7 contains a single central zinc-finger and a C-terminal low-complexity region, but no other recognizable protein domains.
13	apx-1	K08D9.3	n/a	chrV 3,216,670	apx-1 encodes one of ten C. elegans DSL (Delta, Serrate, LAG-2) proteins, integral transmembrane and secreted proteins that function as signaling ligands for the Notch family receptors GLP-1 and LIN-12; in the 4-cell embryo, maternally supplied APX-1 functions as a GLP-1 ligand for an inductive interaction that specifies the fate of the ABp blastomere; later in embryogenesis, APX-1 is required for formation of the LIN-12-dependent, invariant asymmetrical twist that occurs as part of normal gut morphogenesis; during larval development, APX-1 is required redundantly with DSL-1 and LAG-2 for the LIN-12-mediated lateral signal that spatially patterns the primary and secondary vulval cell lineages; in the early embryo, APX-1 is first detected at the anterior edge of the P1 blastomere, with later expression visible in P2 at sites of contact with ABp, and in the cytoplasm of the EMS and P3 blastomeres; expression in the vulval precursor cells (VPCs) is detected in the primary VPC, P6.p, and its descendants; embryonic APX-1 expression is dependent upon PIE-1 activity, while later vulval expression is mediated by the Ras signaling pathway and the SUR-2 transcriptional cofactor.
14	C44H4.6	C44H4.6	n/a	chrX 14,597,741	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
15	str-141	F47G9.2	n/a	chrV 11,323,048	C. elegans STR-141 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	Y47D3B.4	Y47D3B.4	n/a	chrIII 11,407,290	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
17	F09E10.6	F09E10.6	n/a	chrX 1,496,339
18	srg-59	C24B9.7	n/a	chrV 2,724,113	C. elegans SRG-59 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
19	ZK380.2	ZK380.2	n/a	chrX 1,633,167	contains similarity to Interpro domain IPR011072 (HR1 rho-binding repeat)
20	T02G5.11	T02G5.11	n/a	chrII 7,080,284	contains similarity to Pfam domain PF05741 Nanos RNA binding domain contains similarity to Interpro domain IPR008705 (Zinc finger, Nanos)
21	nhr-268	K06B4.6	n/a	chrV 15,690,903	C. elegans NHR-268 protein
22	F47B7.5	F47B7.5	n/a	chrX 3,768,291	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
23	srz-32	W05E7.2	n/a	chrIV 3,437,096	C. elegans SRZ-32 protein; contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
24	E04A4.6	E04A4.6	n/a	chrIV 4,746,804	contains similarity to Homo sapiens Isoform 5 of Tectonic-1 precursor; ENSEMBL:ENSP00000380771
25	B0511.5	B0511.5	n/a	chrI 10,630,197	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
26	str-205	C02E7.9	n/a	chrV 4,929,096	C. elegans STR-205 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	hlh-29	F31A3.4	n/a	chrX 17,548,141	C. elegans HLH-29 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
28	gcy-27	C06A12.4	n/a	chrIV 17,436,419	C. elegans GCY-27 protein; contains similarity to Pfam domains PF00211 (Adenylate and Guanylate cyclase catalytic domain) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001054 (Adenylyl cyclase class-3/4/guanylyl cyclase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
29	Y116A8C.9	Y116A8C.9	n/a	chrIV 16,943,608	contains similarity to Danio rerio Transmembrane protein 185-like.; SW:Q7SYC7
30	F44G3.10	F44G3.10	n/a	chrV 16,139,209	F44G3.10 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F44G3.10 is worm-specific, with obvious homologs only in C. elegans; F44G3.10 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
31	str-122	W03D2.10	n/a	chrIV 4,067,151	C. elegans STR-122 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	srab-13	F59A7.3	n/a	chrV 2,026,295	C. elegans SRAB-13 protein ;
33	F20H11.6	F20H11.6	n/a	chrIII 6,599,869
34	srbc-66	T24A6.5	n/a	chrV 3,531,539	C. elegans SRBC-66 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
35	srm-3	F58G6.2	n/a	chrIV 9,649,830	C. elegans SRM-3 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	clec-195	Y116A8C.21	n/a	chrIV 17,044,558	C. elegans CLEC-195 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
37	F35F10.14	F35F10.14	n/a	chrV 3,319,580
38	sre-40	T05A7.8	n/a	chrII 4,682,734	C. elegans SRE-40 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
39	C05E4.7	C05E4.7	n/a	chrV 742,319
40	str-257	C01B4.1	n/a	chrV 2,519,650	C. elegans STR-257 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	Y7A5A.7	Y7A5A.7	n/a	chrX 15,802,663	contains similarity to Murine herpesvirus 72 Membrane virion glycoprotein 150.; TR:Q9DYE3
42	M153.3	M153.3	n/a	chrX 12,143,295	contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
43	F09F9.3	F09F9.3	n/a	chrX 4,120,310
44	Y116A8C.13	Y116A8C.13	n/a	chrIV 16,956,392	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR000330 (SNF2-related), IPR001395 (Aldo/keto reductase), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
45	F52B11.5	F52B11.5	n/a	chrIV 14,102,592	contains similarity to Clostridium perfringens Hypothetical protein CPE2159.; TR:Q8XIG1
46	W08F4.1	W08F4.1	n/a	chrII 593,688
47	C24A8.5	C24A8.5	n/a	chrX 4,328,634
48	srbc-13	K09C6.5	n/a	chrV 847,788	C. elegans SRBC-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
49	sri-69	Y102A5C.32	n/a	chrV 17,007,786	C. elegans SRI-69 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	C52D10.3	C52D10.3	n/a	chrIV 17,179,526	contains similarity to Pelobacter propionicus DSM 2379 Hypothetical protein precursor.; TR:Q3FZT0