UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C50E3.6	C50E3.6	0	chrV 7,589,517
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	F49C12.14	F49C12.14	n/a	chrIV 9,323,277	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
4	T01D1.5	T01D1.5	n/a	chrII 188,286
5	C09G5.2	C09G5.2	n/a	chrII 10,708,359	C09G5.2 encodes an ortholog of S. cerevisiae DPH2/YKL191W and human DPH2L2 (OMIM:603456); C09G5.2 is a putative protein component of diphtamide synthesis; C09G5.2 has no obvious function in mass RNAi assays.
6	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	nhl-2	F26F4.7	n/a	chrIII 4,896,829	C. elegans NHL-2 protein; contains similarity to Pfam domains PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF00643 (B-box zinc finger) (2), PF01436 (NHL repeat) (4)contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR003649 (B-box, C-terminal), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR000315 (Zinc finger, B-box), IPR001258 (NHL repeat)
8	ZC412.4	ZC412.4	n/a	chrV 14,869,132	contains similarity to Brugia malayi Major allergen.; TR:Q9BJC9
9	F25H2.7	F25H2.7	n/a	chrI 10,559,067	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
10	W06E11.4	W06E11.4	n/a	chrIII 637,463	W06E11.4 encodes an ortholog of human SBDS (OMIM:607444, mutated in Shwachman-Bodian-Diamond syndrome) and S. cerevisiae SDO1; by homology, W06E11.4 is predicted to be a nucleolar protein that may be required for normal processing of rRNA; WS06E11.4 shares an operon with tag-266 and T19C3.7.
11	Y38C9A.1	Y38C9A.1	n/a	chrV 112,782	contains similarity to Leishmania major strain Friedlin Proteophosphoglycan ppg4.; TR:Q4FX63
12	K11E4.2	K11E4.2	n/a	chrX 13,718,299	contains similarity to Pfam domain PF00017 SH2 domain contains similarity to Interpro domains IPR006020 (Phosphotyrosine interaction region), IPR000980 (SH2 motif)
13	prpf-4	F22D6.5	n/a	chrI 7,092,922	C. elegans PRPF-4 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
14	C32H11.11	C32H11.11	n/a	chrIV 12,938,618	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
15	ZK829.7	ZK829.7	n/a	chrIV 11,960,692	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
16	secs-1	D1054.13	n/a	chrV 10,803,314	C. elegans SECS-1 protein; contains similarity to Pfam domain PF05889 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) contains similarity to Interpro domains IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR008829 (Soluble liver antigen/liver pancreas antigen)
17	syn-3	F55A11.2	n/a	chrV 11,766,040	C. elegans SYN-3 protein; contains similarity to Pfam domains PF00804 (Syntaxin) , PF05739 (SNARE domain) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR006011 (Syntaxin, N-terminal), IPR000727 (Target SNARE coiled-coil region), IPR006012 (Syntaxin/epimorphin, conserved site)
18	cka-1	C28D4.2	n/a	chrIV 9,734,654	cka-1 encodes an isoform of choline kinase whose activity has been verified in vitro, and that has a strong preference for choline over ethanolamine; CKA-1 and CKA-2 comprise a related group ('A') of choline kinases.
19	B0281.3	B0281.3	n/a	chrII 2,307,697	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR003058 (Cloacin), IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
20	F22B8.6	F22B8.6	n/a	chrV 16,101,647	F22B8.6 encodes a putative cystathionine gamma-lyase; F22B8.6 is orthologous to human CTH (OMIM:607657, mutated in cystathioninuria), extremely similar to its paralog ZK1127.10, and also paralogous to C12C8.2; either F22B8.6, or ZK1236.10, or both proteins weakly inhibit DHC-1 in vivo; otherwise, F22B8.6 has no obvious function in mass RNAi assays, perhaps because of genetic redundancy with ZK1127.10.
21	C36E8.1	C36E8.1	n/a	chrIII 4,001,753	contains similarity to Pfam domain PF05327 RNA polymerase I specific transcription initiation factor RRN3 contains similarity to Interpro domain IPR007991 (RNA polymerase I specific transcription initiation factor RRN3)
22	T26E3.4	T26E3.4	n/a	chrI 12,666,969	contains similarity to Pfam domain PF05773 RWD domain contains similarity to Interpro domains IPR006575 (RWD), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like)
23	F56G4.6	F56G4.6	n/a	chrI 11,369,184	contains similarity to Interpro domain IPR001623 (Heat shock protein DnaJ, N-terminal)
24	rabn-5	F01F1.4	n/a	chrIII 5,865,475	C. elegans RABN-5 protein; contains similarity to Pfam domains PF09311 (Rab5 binding) , PF01363 (FYVE zinc finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002867 (Zinc finger, C6HC-type), IPR015390 (Rabaptin, GTPase-Rab5 binding), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
25	uev-1	F39B2.2	n/a	chrI 14,790,521	uev-1 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the characteristic UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-1 in C. elegans development and/or behavior is not yet known; UEV-1 does, however, interact with a number of proteins, such as UBC-13, that are likely involved in the response to DNA damage; thus, UEV-1 may play a role in ubiquitination and protein turnover in conjunction with DNA repair or the DNA damage checkpoint pathway.
26	clec-35	Y102A5B.2	n/a	chrV 16,853,143	C. elegans CLEC-35 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
27	K07A12.1	K07A12.1	n/a	chrI 8,668,182	contains similarity to Pfam domain PF04910 Protein of unknown function, DUF654 contains similarity to Interpro domains IPR006994 (Basic helix-loop-helix, Nulp1-type), IPR000294 (Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)
28	kin-4	C10C6.1	n/a	chrIV 11,441,819	C. elegans KIN-4 protein; contains similarity to Pfam domains PF08926 (Domain of unknown function (DUF1908)) , PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR015022 (Region of unknown function DUF1908), IPR000719 (Protein kinase, core), IPR001478 (PDZ/DHR/GLGF), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
29	cyp-25A2	C36A4.2	n/a	chrIII 3,836,163	C. elegans CYP-25A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
30	dnj-17	T03F6.2	n/a	chrIII 13,392,282	This gene encodes a protein containing a DnaJ ('J') domain.
31	R07G3.5	R07G3.5	n/a	chrII 7,598,098	contains similarity to Pfam domain PF00300 Phosphoglycerate mutase family contains similarity to Interpro domain IPR013078 (Phosphoglycerate mutase)
32	F13G3.6	F13G3.6	n/a	chrI 7,304,082	contains similarity to Pfam domain PF00535 Glycosyl transferase family 2 contains similarity to Interpro domains IPR001173 (Glycosyl transferase, family 2), IPR016040 (NAD(P)-binding)
33	asna-1	ZK637.5	n/a	chrIII 8,895,772	asna-1 encodes a putative membrane transporter that is required, non-cell-autonomously, for L1 larvae to proceed through development when fed, and is also required for normal insulin (DAF-28) secretion; the human ASNA1 ortholog stimulates insulin secretion in pancreatic beta cells, and can transgenically rescue asna-1 mutant C. elegans, suggesting that ASNA-1's function is conserved among metazoa; asna-1 mutants only progress to adulthood when rescued by maternal ASNA-1; without maternal rescue, asna-1 mutants eat food and endocytose nutrients normally, but nevertheless arrest growth as L1 larvae and localize DAF-16 to the nucleus as if food were absent; asna-1 is expressed in some sensory neurons, in insulin-producing intestinal cells, and in hypodermis; ASNA-1 positively regulates dauer exit in the same way that overexpression of the insulins DAF-28 or INS-4 does, and requires DAF-28 to do this efficiently; ASNA-1 has ATPase activity in vitro, and this activity is required for transgenic rescue of asna-1 mutations.
34	pqn-96	ZK1236.6	n/a	chrIII 8,438,835	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
35	exoc-7	C43E11.8	n/a	chrI 4,245,201	C. elegans EXOC-7 protein; contains similarity to Pfam domain PF03081 Exo70 exocyst complex subunit contains similarity to Interpro domain IPR004140 (Exo70 exocyst complex subunit)
36	T03G11.4	T03G11.4	n/a	chrX 5,167,050	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
37	F53F4.3	F53F4.3	n/a	chrV 13,592,537	F53F4.3 encodes a putative alpha-tubulin folding cofactor B, orthologous to human CKAP1 (OMIM:601303); F53F4.3 is dispensable in early embryos for microtubule nucleation or elongation, and has no obvious function in mass RNAi assays.
38	pqn-51	K11D12.2	n/a	chrV 5,050,974	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
39	W06D11.4	W06D11.4	n/a	chrX 12,302,364	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
40	ndx-9	F13H10.2	n/a	chrIV 11,010,995	The ndx-9 gene encodes a member of the NADH pyrophosphatase subfamily of the NUDIX hydrolases.
41	ifa-4	K05B2.3	n/a	chrX 4,914,125	IFA-4 encodes a nonessential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-4 binds IFB-1 in blot overlay assays; ifa-4 is expressed in larvae in the pharyngeal-intestinal valve, the rectum, some neurons of the tail, the excretory cell, and the intestine of dauer (but not nondauer) larvae; IFA-4 has no function in RNAi assays.
42	W08D2.5	W08D2.5	n/a	chrIV 9,821,001	contains similarity to Pfam domains PF00122 (E1-E2 ATPase) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR008250 (E1-E2 ATPase-associated region), IPR006544 (P-type ATPase of unknown pump specificity (type V)), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR000150 (Cof protein), IPR005834 (Haloacid dehalogenase-like hydrolase)
43	fbxa-60	T12B5.10	n/a	chrIII 945,562	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
44	C53D6.7	C53D6.7	n/a	chrIV 9,035,988	contains similarity to Pfam domain PF00337 Galactoside-binding lectin contains similarity to Interpro domains IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
45	clec-265	M02F4.7	n/a	chrX 3,032,455	C. elegans CLEC-265 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
46	ilys-2	C45G7.2	n/a	chrIV 2,468,243	C. elegans ILYS-2 protein; contains similarity to Pfam domain PF05497 Destabilase contains similarity to Interpro domain IPR008597 (Destabilase)
47	C30G12.2	C30G12.2	n/a	chrII 7,290,986	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
48	bch-1	F25H2.13	n/a	chrI 10,574,565	C. elegans BCH-1 protein; contains similarity to Pfam domain PF06733 DEAD_2 contains similarity to Interpro domains IPR014013 (Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type), IPR010614 (DEAD2), IPR002464 (DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site), IPR006554 (Helicase-like, DEXD box c2 type), IPR006555 (Helicase, ATP-dependent, c2 type), IPR014001 (DEAD-like helicase, N-terminal), IPR013020 (DNA helicase (DNA repair), Rad3 type)
49	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
50	nsh-1	F20H11.2	n/a	chrIII 6,595,590	C. elegans NSH-1 protein; contains similarity to Pfam domain PF00271 Helicase conserved C-terminal domain contains similarity to Interpro domains IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)