UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sru-31	C50C10.4	1e-173	chrV 9,817,248	C. elegans SRU-31 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR002229 (Blood group Rhesus C/E and D polypeptide), IPR003839 (Protein of unknown function DUF215)
2	F35F10.7	F35F10.7	n/a	chrV 3,286,914	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
3	F59H5.1	F59H5.1	n/a	chrII 2,509,863	F59H5.1 encodes an unfamiliar protein with a low-complexity N-terminal region and a C-terminal DUF545 motif (of unknown function, found solely in nematode proteins); F59H5.1 is expressed in neuronal head ganglia, intestinal cells, hypodermal cells, and coelomocytes, with strong expression in embryos; F59H5.1 has no obvious function or phenotype in RNAi assays, whether in a normal background or in goa-1(-) or goa-1(gf) mutant backgrounds.
4	ZK1240.2	ZK1240.2	n/a	chrII 2,324,281	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
5	F41H10.4	F41H10.4	n/a	chrIV 5,365,559	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2DDX5
6	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
7	btb-9	F45C12.4	n/a	chrII 1,729,278	C. elegans BTB-9 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
8	F14B6.4	F14B6.4	n/a	chrI 12,237,119	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
9	T27A8.1	T27A8.1	n/a	chrX 16,052,166	T27A8.1 encodes a putative metallocarboxypeptidase orthologous to human AEBP1 (OMIM:602981) and carboxypeptidase D, E, M, N, X2, and Z precursors; T27A8.1 and its human orthologs, along with other proteins, comprise an M14B peptidase subfamily; T27A8.1 has no obvious function in mass RNAi assays.
10	C33D12.2	C33D12.2	n/a	chrX 3,043,877	C33D12.2 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C33D12.2 may participate in metal homoeostasis; C33D12.2 is expressed in intestine, body wall muscle, nervous system (including ventral and dorsal nerve cords and head neurons), and adult vulval muscle and reproductive system; C33D12.2, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C33D12.2 has no obvious function in RNAi assays.
11	gcy-34	M04G12.3	n/a	chrV 13,384,440	gcy-34 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-34 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-34 in C. elegans development and/or behavior is not yet known; GCY-34 expression in neurons connected to the pseudocoelom suggests, however, that GCY-34 may play a role in fluid homeostasis.
12	F20D1.4	F20D1.4	n/a	chrX 14,982,392	contains similarity to Pfam domain PF04845 PurA ssDNA and RNA-binding protein contains similarity to Interpro domain IPR006628 (PUR-alpha/beta/gamma, DNA/RNA-binding)
13	gcy-4	ZK970.5	n/a	chrII 10,306,418	gcy-4 encodes a predicted transmembrane guanylyl cyclase; by homology, GCY-4 may function as a chemosensory receptor; however, as loss of gcy-4 activity via mutation or large-scale RNAi screens results in no obvious abnormalities, the precise role of gcy-4 in C. elegans development and/or behavior is not yet known; the sole gcy-4 ::GFP reporter construct reported to date did not produce any specific GFP signals.
14	fbxa-133	C38D9.4	n/a	chrV 17,585,301	C. elegans FBXA-133 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
15	srx-66	K07C6.9	n/a	chrV 3,920,192	C. elegans SRX-66 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
16	C45G9.7	C45G9.7	n/a	chrIII 5,046,619	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domains IPR017268 (Tax1-binding protein 3), IPR001478 (PDZ/DHR/GLGF)
17	F47B7.6	F47B7.6	n/a	chrX 3,770,172
18	F35F10.5	F35F10.5	n/a	chrV 3,285,611
19	rnt-1	B0414.2	n/a	chrI 5,782,356	rnt-1 encodes a transcription factor that is the sole C. elegans member of the RUNX family of transcriptional regulators; rnt-1 activity is required for several developmental processes, including regulation of hypodermal seam cell proliferation and proper development of the male tail; RNT-1 can physically interact with SMA-4 and regulates, either directly or indirectly, expression of tlp-1 and cki-1, which encode a C2H2 zinc finger and CDK inhibitor, respectively; RNT-1::GFP reporter fusions are reportedly expressed in the nuclei of hypodermal seam cells, intestinal cells, body wall muscles, and, in males, cells derived from the V5, V6 and T lineages that give rise to the sensory rays.
20	R11G10.2	R11G10.2	n/a	chrV 13,513,568	contains similarity to Pfam domain PF05694 56kDa selenium binding protein (SBP56) contains similarity to Interpro domain IPR008826 (Selenium-binding protein)
21	F47B10.5	F47B10.5	n/a	chrX 10,889,736	contains similarity to Xenopus laevis D(2) dopamine receptor 1.; SW:D2D1_XENLA
22	math-2	C08F1.1	n/a	chrII 1,799,617	C. elegans MATH-2 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
23	B0222.9	B0222.9	n/a	chrV 9,170,672	contains similarity to Pfam domains PF00941 (FAD binding domain in molybdopterin dehydrogenase) , PF02738 (Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain) , PF00111 (2Fe-2S iron-sulfur cluster binding domain) , PF01799 ([2Fe-2S] binding domain) , PF01315 (Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR001041 (Ferredoxin), IPR002346 (Molybdopterin dehydrogenase, FAD-binding), IPR012675 (Beta-grasp fold, ferredoxin-type), IPR002888 ([2Fe-2S]-binding), IPR016166 (FAD-binding, type 2), IPR006058 (2Fe-2S ferredoxin, iron-sulphur binding site), IPR016169 (CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2), IPR000674 (Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead), IPR008274 (Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)
24	F16H6.7	F16H6.7	n/a	chrV 18,208,098	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
25	str-225	C07G3.6	n/a	chrV 3,508,534	C. elegans STR-225 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001307 (Thiosulphate sulphurtransferase, conserved site)
26	mxl-3	F46G10.6	n/a	chrX 13,350,149	C. elegans MXL-3 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding), IPR002418 (Transcription regulator Myc)
27	str-94	F07C3.8	n/a	chrV 9,248,642	C. elegans STR-94 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR005384 (Duffy antigen/chemokine receptor)
28	R11G11.3	R11G11.3	n/a	chrV 531,412	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
29	C46H11.1	C46H11.1	n/a	chrI 5,055,865
30	ZK1240.3	ZK1240.3	n/a	chrII 2,321,141	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
31	Y39A3B.1	Y39A3B.1	n/a	chrIII 2,007,600
32	srj-29	F22B8.1	n/a	chrV 16,076,456	C. elegans SRJ-29 protein; contains similarity to Pfam domains PF00060 (Ligand-gated ion channel) , PF01094 (Receptor family ligand binding region) contains similarity to Interpro domains IPR001638 (Bacterial extracellular solute-binding protein, family 3), IPR015683 (Glutamate receptor-related), IPR001320 (Ionotropic glutamate receptor), IPR001828 (Extracellular ligand-binding receptor), IPR001508 (NMDA receptor)
33	ndx-3	Y38A8.1	n/a	chrII 4,954,109	The ndx-3 gene encodes a homolog of peroxisomal CoA diphosphatases in both S. cerevisiae (PCD1) and C. elegans (NDX-8); more generally, NDX-3 protein belongs to the family of NUDIX hydrolases.
34	C53A5.9	C53A5.9	n/a	chrV 14,557,956	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF07646 (Kelch motif) (3), PF02984 (Cyclin, C-terminal domain) contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR004367 (Cyclin, C-terminal), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
35	F48E8.3	F48E8.3	n/a	chrIII 5,462,687	contains similarity to Pfam domains PF00890 (FAD binding domain) , PF01266 (FAD dependent oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR010960 (Flavocytochrome c), IPR006076 (FAD dependent oxidoreductase), IPR003953 (Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal), IPR016040 (NAD(P)-binding)
36	ugt-34	F29F11.2	n/a	chrV 10,655,665	ugt-34 encodes a putative UDP-glucuronosyltransferase (UGT), belonging to a large nematode-specific expanded family of UGTs, that inhibits CEP-1- and HUS-1-dependent germline apoptosis as do BMK-1, RAD-50, and RAD-51.
37	C34C12.7	C34C12.7	n/a	chrIII 3,485,435
38	sqv-8	ZK1307.5	n/a	chrII 9,648,550	The sqv-8 gene encodes a glucuronyl transferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-8 is homologous to three distinct glucuronyl transferases (GlcAT-I, GlcAT-P and GlcAT-D) that play a role in the synthesis of different glycoconjugates; the common requirement for SQV-8 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
39	F59B10.2	F59B10.2	n/a	chrII 10,508,511	contains similarity to Interpro domains IPR003993 (Treacher Collins syndrome, treacle), IPR005819 (Histone H5)
40	srj-1	ZK829.8	n/a	chrIV 11,964,638	C. elegans SRJ-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	T22C8.7	T22C8.7	n/a	chrII 8,632,480	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
42	gpa-13	F18E2.5	n/a	chrV 12,753,806	gpa-13 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASH, AWC, PHA, and PHB.
43	VC5.2	VC5.2	n/a	chrV 7,087,384	contains similarity to Pfam domain PF00053 Laminin EGF-like (Domains III and V) contains similarity to Interpro domains IPR006056 (YjgF-like protein), IPR006210 (EGF), IPR002049 (EGF-like, laminin)
44	ZK353.2	ZK353.2	n/a	chrIII 8,398,849	contains similarity to Interpro domain IPR002952 (Eggshell protein)
45	Y38F1A.8	Y38F1A.8	n/a	chrII 12,999,329	contains similarity to Homo sapiens Isoform 2 of Post-GPI attachment to proteins factor 2; ENSEMBL:ENSP00000300730
46	B0391.3	B0391.3	n/a	chrV 15,616,248	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000802 (Arsenical pump membrane protein)
47	F13E9.4	F13E9.4	n/a	chrIV 10,895,888	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domains IPR000775 (Bindin), IPR008119 (Dense granule Gra6 protein), IPR003677 (Protein of unknown function DUF148)
48	Y32B12C.3	Y32B12C.3	n/a	chrV 16,613,751	contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
49	srb-15	C48B6.5	n/a	chrI 6,899,186	C. elegans SRB-15 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
50	C33E10.10	C33E10.10	n/a	chrX 17,301,563	contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)