UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C49D10.8	C49D10.8	0	chrII 3,859,527	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
2	F58H7.8	F58H7.8	n/a	chrIV 908,458
3	F09C12.6	F09C12.6	n/a	chrII 5,117,137	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
4	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
5	Y76A2B.5	Y76A2B.5	n/a	chrIII 13,547,827	contains similarity to Danio rerio Zgc:91819 protein.; TR:Q6GMH4
6	haf-1	C30H6.6	n/a	chrIV 17,377,825	haf-1 encodes a predicted transmembrane protein of the ATP-binding cassette (ABC) transporter superfamily; by homology, HAF-1 is proposed to function in ATP-dependent transport of molecules across plasma and intracellular membranes; however, as loss of HAF-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HAF-1 in C. elegans development and/or behavior is not yet known.
7	pah-1	K08F8.4	n/a	chrII 8,763,866	pah-1 encodes a biochemically active phenylalanine-4-hydroxylase orthologous to human PAH (OMIM:261600, mutated in phenylketonuria); recombinant PAH-1 has hydroxylase activity on phenylalanine and tryptophan substrates in vitro; pah-1 is expressed in seam cells, tail hypodermal cells, and ventral hypodermis, with stronger posterior than anterior expression; PAH-1 might help provide tyrosine for cross-linking in the cuticle, and is partially required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
8	bath-26	T07H3.6	n/a	chrII 1,600,097	C. elegans BATH-26 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
9	R09D1.10	R09D1.10	n/a	chrII 9,465,285	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
10	R08E3.2	R08E3.2	n/a	chrX 4,823,223	contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site)
11	ttr-24	Y51A2D.9	n/a	chrV 18,555,981	C. elegans TTR-24 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
12	F56H11.6	F56H11.6	n/a	chrIV 9,528,961	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
13	btb-16	F39E9.2	n/a	chrII 3,297,442	C. elegans BTB-16 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
14	btb-4	F59H6.12	n/a	chrII 2,032,856	C. elegans BTB-4 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
15	snt-2	F42G9.7	n/a	chrIII 789,889	C. elegans SNT-2 protein; contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
16	K11E4.1	K11E4.1	n/a	chrX 13,715,160	contains similarity to Pfam domain PF01764 (Lipase (class 3))
17	srp-6	C03G6.19	n/a	chrV 7,385,156	srp-6 encodes a functional serpin (serine protease inhibitor)
18	T18D3.8	T18D3.8	n/a	chrX 12,437,812
19	Y11D7A.1	Y11D7A.1	n/a	chrIV 9,229,724	contains similarity to Interpro domains IPR003702 (Acetyl-CoA hydrolase/transferase), IPR001220 (Legume lectin, beta domain)
20	mtl-2	T08G5.10	n/a	chrV 14,018,435	mtl-2 encodes one of two C. elegans metallothioneins, small, cysteine-rich, metal-binding proteins; MTL-2 functions in metal detoxification and homeostasis and stress adaptation; in addition, mtl-2 plays a role in regulating growth and fertility; mtl-2 expression is induced in larval and adult intestinal cells following exposure to cadmium or heat shock; MTL-2 intestinal expression is dependent upon ELT-2, an intestine-specific GATA-type transcription factor; mtl-2 is downregulated by DAF-16 in daf-2 mutants.
21	R06B10.2	R06B10.2	n/a	chrIII 975,911	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
22	F56G4.1	F56G4.1	7e-37	chrI 11,343,556	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
23	C36C5.15	C36C5.15	n/a	chrV 3,168,358	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
24	F23H11.6	F23H11.6	n/a	chrIII 914,468
25	ZC15.5	ZC15.5	n/a	chrV 20,294,125	contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
26	Y26G10.1	Y26G10.1	n/a	chrV 17,694,131	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF07974 (EGF-like domain) (3)contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR001774 (Delta/Serrate/lag-2 (DSL) protein), IPR000742 (EGF-like, type 3), IPR015919 (Cadherin-like), IPR011050 (Pectin lyase fold/virulence factor), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR006626 (Parallel beta-helix repeat), IPR013032 (EGF-like region, conserved site), IPR002126 (Cadherin), IPR013111 (EGF, extracellular)
27	R07B1.8	R07B1.8	n/a	chrX 9,871,676
28	srp-8	F20D6.3	n/a	chrV 8,184,913	srp-8 encodes a predicted serpin (serine protease inhibitor)
29	C43D7.7	C43D7.7	n/a	chrV 19,319,210	contains similarity to Dictyostelium discoideum Filament-interacting protein.; TR:Q967Y0
30	F11A10.4	F11A10.4	n/a	chrIV 12,101,240	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR013324 (RNA polymerase sigma factor, regions 3 and 4), IPR016024 (Armadillo-type fold)
31	che-11	C27A7.4	n/a	chrV 12,147,469	che-11 encodes a large, unfamiliar protein with orthologs in vertebrates and arthropods (e.g., KIAA0590 and CG11838-PA) and in Chlamydomonas (IFT140), as well as distant similarity to OSM-1 and ZK520.1; che-11 is required for normal synthesis of sensory cilia (via intraflagellar transport) in sensory neurons, osmotic avoidance, and dauer formation.
32	clec-40	T20B3.13	n/a	chrV 16,840,047	C. elegans CLEC-40 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
34	F25E5.4	F25E5.4	n/a	chrV 7,450,232	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
35	smgl-1	F20G4.1	n/a	chrI 7,922,384	C. elegans SMGL-1 protein; contains similarity to Interpro domain IPR011046 (WD40 repeat-like)
36	R07C12.3	R07C12.3	n/a	chrIV 4,145,897
37	str-151	T03E6.1	n/a	chrV 16,577,135	C. elegans STR-151 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	T20D4.12	T20D4.12	n/a	chrV 3,397,421	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
39	C01F1.4	C01F1.4	n/a	chrII 4,277,663	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
40	T24C2.5	T24C2.5	n/a	chrX 14,538,539	contains similarity to Homo sapiens Nuclear receptor co-repressor 1; ENSEMBL:ENSP00000268712
41	B0507.2	B0507.2	n/a	chrV 8,775,382	contains similarity to Interpro domain IPR004328 (BRO1)
42	T21H3.4	T21H3.4	n/a	chrV 1,144,046	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
43	abf-4	Y38H6C.22	n/a	chrV 20,553,545	abf-4 encodes a homolog of the antibacterial factor ASABF from Ascaris suum; ABF-4 may play a role in innate immunity, though at present the only evidence for its having an antimicrobial humoral function is its sequence similarity.
44	let-70	M7.1	n/a	chrIV 11,081,640	let-70 encodes a class I E2 ubiquitin conjugating enzyme; let-70 was identified in screens for essential genes and phenotypic analyses indicate that loss of let-70 activity results in embryonic and larval lethality with defects in sarcomere assembly; purified LET-70 can stimulate the self-ubiquitylation activities of CHN-1 and UFD-2, E4 ubiquitin conjugation factors and, in addition, can stimulate the CHN-1- and UFD-2-dependent multiubiquitylation of UNC-45, a myosin-directed chaperone; in this manner, LET-70 may regulate UNC-45 degradation and myosin assembly; RNA blot analyses and a let-70-lacZ reporter fusion reveal that let-70 is abundantly expressed at all stages of development, including the dauer larval stage; strong staining is observed in most somatic tissues until adult stages, when expression generally becomes restricted to the nervous system.
45	rps-8	F42C5.8	n/a	chrIV 7,313,435	rps-8 encodes a small ribosomal subunit S8 protein; by homology, RPS-8 is predicted to function in protein biosynthesis; in C. elegans, RPS-8 activity is required for germline development and the overall health of the animal.
46	C14C6.12	C14C6.12	n/a	chrV 570,875	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
47	R53.4	R53.4	n/a	chrII 9,967,683	contains similarity to Homo sapiens 10 kDa protein; ENSEMBL:ENSP00000377740
48	C30H6.8	C30H6.8	n/a	chrIV 17,382,648	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related)
49	frm-9	F31B12.3	n/a	chrX 10,817,663	frm-9 encodes a B41/ERM (ezrin/radixin/moesin) domain containing protein.
50	lin-31	K10G6.1	n/a	chrII 3,984,762	lin-31 encodes a winged helix (WH)-like transcription factor that is a member of the HNF3/Forkhead family of DNA-binding proteins; LIN-31 acts as a tissue-specific effector of MAP kinase-mediated signaling in the vulva; when MAP kinase is inactive, LIN-31 forms a complex with LIN-1/Ets that inhibits vulval cell fates; upon MAP kinase activation (vulval induction), LIN-31 becomes phosphorylated, dissociates from LIN-1, and goes on to promote primary and secondary vulval cell fates; LIN-31 is expressed in the vulval precursor cells.