UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C49A9.1	C49A9.1	0	chrIV 6,229,082	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C35A5.7	C35A5.7	n/a	chrV 10,512,499	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
4	atp-4	T05H4.12	n/a	chrV 6,426,736	C. elegans ATP-4 protein; contains similarity to Pfam domain PF05511 Mitochondrial ATP synthase coupling factor 6 contains similarity to Interpro domain IPR008387 (ATPase, F0 complex, subunit F6, mitochondrial)
5	T07F10.6	T07F10.6	n/a	chrV 12,865,830	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
6	tsr-1	F53G2.6	n/a	chrII 2,466,865	tsr-1 encodes a homolog of human transportin-SR, a nuclear transport receptor, and affects embryonic viability.
7	srz-15	C32H11.2	n/a	chrIV 12,916,637	C. elegans SRZ-15 protein ;
8	Y38H6C.4	Y38H6C.4	n/a	chrV 20,500,386	contains similarity to Mus musculus Similar to hypothetical protein FLJ21522 (Epidermal growth factorsreceptor pathway substrate 8 related protein 3).; TR:Q91WL0
9	F53B6.6	F53B6.6	n/a	chrI 8,956,012	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
10	F18F11.4	F18F11.4	n/a	chrIV 332,622	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
11	cdc-42	R07G3.1	n/a	chrII 7,617,275	cdc-42 encodes a RHO GTPase which controls polarity of both individual cells and developing embryos by regulating the localization of PAR proteins; CDC-42 is expressed at hypodermal cell boundaries; cdc-42 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults.
12	ZC239.15	ZC239.15	n/a	chrII 3,224,089	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
13	cmk-1	K07A9.2	n/a	chrIV 1,829,288	cmk-1 encodes a Ca+2/calmodulin-dependent protein kinase I (CaMK1); CMK-1 activity is required, cell autonomously and downstream of the cyclic nucleotide-gated channel TAX-4, for several aspects of AFD thermosensory neuron differentiation, including expression of the gcy-8 guanylyl cyclase and nhr-38 nuclear hormone receptor genes and morphology of the AFD sensory endings; cmk-1 activity is thus also required for normal thermosensory behavior; a cmk-1::gfp reporter is expressed in head sensory and interneurons as well as in the ventral nerve cord; expression is seen specifically in the neurons of the thermosensory circuit, AFD, AIY, and AIZ; CMK-1 localizes exclusively to the cytoplasm.
14	W09H1.3	W09H1.3	n/a	chrII 13,184,626	contains similarity to Homo sapiens cDNA FLJ31139 fis, clone IMR322001185; ENSEMBL:ENSP00000380962
15	nhr-54	F36D3.2	n/a	chrV 16,504,904	C. elegans NHR-54 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
16	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
17	gop-1	C34E10.3	n/a	chrIII 5,256,655	C. elegans GOP-1 protein; contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
18	mom-1	T07H6.2	n/a	chrX 6,295,619	mom-1 encodes a predicted O-acyltransferase that is orthologous to Porcupine proteins conserved across a wide range of species; MOM-1 functions as part of a Wnt/MAPK signaling pathway that is required maternally for endoderm induction in the early embryo; by homology, MOM-1 is predicted to be a membrane-spanning endoplasmic reticulum protein that stimulates post-translational processing of Wnt signaling molecules such as MOM-2; embryonic mosaic analysis indicates that MOM-1 activity is required in the signaling cell, P2, for proper specification of endoderm, consistent with its predicted role in processing MOM-2/Wnt.
19	F14F8.8	F14F8.8	n/a	chrV 16,671,873	contains similarity to Saccharomyces cerevisiae Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP; SGD:YHR143W
20	cyp-13A12	F14F7.3	n/a	chrIII 13,026,202	C. elegans CYP-13A12 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
21	T16A9.4	T16A9.4	n/a	chrV 14,218,017	T16A9.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while T16A9.4 has no clear orthologs in other organisms, it falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).
22	F49B2.3	F49B2.3	n/a	chrI 14,311,927	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region)
23	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
24	ZK892.3	ZK892.3	n/a	chrII 10,002,830	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
25	D1014.7	D1014.7	n/a	chrV 8,119,293	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
26	ced-3	C48D1.2	n/a	chrIV 13,202,258	The ced-3 gene encodes a protease required for apoptosis.
27	C11G10.1	C11G10.1	n/a	chrX 15,157,907
28	R102.6	R102.6	n/a	chrIV 10,699,884	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
29	Y6B3B.4	Y6B3B.4	n/a	chrI 13,765,684	contains similarity to Interpro domain IPR000533 (Tropomyosin)
30	clk-1	ZC395.2	n/a	chrIII 5,278,572	clk-1 encodes the C. elegans ortholog of COQ7/CAT5, a highly conserved demethoxyubiquinone (DMQ) hydroxylase that is necessary for the biosynthesis of ubiquinone (coenzyme Q, Q9) from 5-demethoxyubiquinone (DMQ9); in C. elegans, CLK-1 activity is required for normal physiological rates of growth, development, behavior, and aging, as well as for normal brood sizes.
31	T05B4.4	T05B4.4	n/a	chrV 4,128,560
32	math-39	T08E11.2	n/a	chrII 1,832,929	C. elegans MATH-39 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
33	F49E12.8	F49E12.8	n/a	chrII 8,393,450	contains similarity to Homo sapiens Hypothetical protein KIAA0335; TR:O15044
34	fip-4	F41E6.10	n/a	chrV 8,611,069	C. elegans FIP-4 protein
35	F15D4.6	F15D4.6	n/a	chrII 13,249,439	contains similarity to Bacillus halodurans Acetolactate synthase large subunit.; TR:Q9K8E5
36	W09G12.9	W09G12.9	n/a	chrIV 1,217,448
37	sri-10	C54E10.4	n/a	chrV 18,805,260	C. elegans SRI-10 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR016040 (NAD(P)-binding)
38	T08E11.8	T08E11.8	n/a	chrII 1,834,708	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
39	K05C4.10	K05C4.10	n/a	chrI 14,725,700	contains similarity to Enterococcus faecalis Hypothetical protein.; TR:Q836A3
40	C18G1.6	C18G1.6	n/a	chrV 4,752,187	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
41	M163.5	M163.5	n/a	chrX 14,475,017	contains similarity to Interpro domain IPR008995 ()
42	T26F2.2	T26F2.2	n/a	chrV 13,982,237	contains similarity to Homo sapiens Isoform 1 of Protein Dom3Z; ENSEMBL:ENSP00000337759
43	E04F6.4	E04F6.4	n/a	chrII 7,190,903	contains similarity to Pfam domains PF08371 (Phospholipase D/viral envelope) , PF00614 (Phospholipase D Active site motif) (2)contains similarity to Interpro domains IPR013582 (Phospholipase D/viral envelope), IPR001736 (Phospholipase D/Transphosphatidylase)
44	K08B5.2	K08B5.2	n/a	chrX 16,552,470
45	T01B10.5	T01B10.5	n/a	chrX 8,496,580
46	nhr-227	T27B7.5	n/a	chrV 2,286,399	C. elegans NHR-227 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
47	ugt-61	F39G3.1	n/a	chrV 4,743,888	C. elegans UGT-61 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
48	C23H5.7	C23H5.7	n/a	chrIV 2,107,829	contains similarity to Pfam domains PF00027 (Cyclic nucleotide-binding domain) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000595 (Cyclic nucleotide-binding), IPR014710 (RmlC-like jelly roll fold)
49	srx-116	W05B10.5	n/a	chrV 12,671,795	C. elegans SRX-116 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
50	T25G12.1	T25G12.1	n/a	chrX 17,249,457