UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srx-18	C47A10.8	2e-144	chrV 17,797,511	C. elegans SRX-18 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
5	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
6	col-41	T10B10.1	n/a	chrX 15,175,685	col-41 encodes a cuticle collagen.
7	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
8	F38B6.2	F38B6.2	n/a	chrX 6,699,255	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
9	nhr-106	T01G6.4	n/a	chrV 490,539	nhr-106 encodes a nuclear receptor that is most highly conserved amongst nematode species.
10	srx-102	F40H7.5	n/a	chrII 3,694,076	C. elegans SRX-102 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
11	col-131	C39E9.3	n/a	chrIV 13,066,496	C. elegans COL-131 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
12	ugt-32	F47C10.6	n/a	chrV 3,842,918	C. elegans UGT-32 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
13	pax-3	F27E5.2	n/a	chrII 10,149,568	pax-3 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; PAX-3 is required for locomotion and vulval development; pax-3(RNAi) animals have consistent Pvl and Unc phenotypes (as well as less consistent Bmd, Rup, and Stp phenotypes).
14	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
15	srw-107	R11G11.13	n/a	chrV 520,735	C. elegans SRW-107 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
16	R13H4.6	R13H4.6	n/a	chrV 11,864,309	contains similarity to Archaeoglobus fulgidus Putative protease La homolog type (EC 3.4.21.-).; SW:O29883
17	C33F10.1	C33F10.1	n/a	chrII 4,835,359
18	xtr-1	F54F7.4	n/a	chrX 11,852,038	xtr-1 encodes a protein with similarity to TRA-2A and TRA-2B in a region known as the MX region, hypothesized to be a protein-protein interaction domain involved in negatively regulating tra-2 activity in the germ line.
19	sre-23	ZK265.5	n/a	chrI 8,257,642	C. elegans SRE-23 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
20	scl-27	ZK6.3	n/a	chrV 400,930	C. elegans SCL-27 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
21	tba-8	ZK899.4	n/a	chrX 9,456,854	tba-8 encodes a member of the alpha tubulin family with high similarity to the human tubulin alpha-6 chain; expressed in some neurons with occasional expression in the hypodermis.
22	B0304.2	B0304.2	n/a	chrII 4,524,073
23	F47B8.5	F47B8.5	n/a	chrV 14,326,311	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domains IPR002485 (Protein of unknown function DUF13), IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein), IPR003071 (Orphan nuclear receptor, HMR type)
24	srv-32	T13A10.12	n/a	chrIV 6,281,179	C. elegans SRV-32 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
25	F12A10.8	F12A10.8	n/a	chrII 5,500,103
26	T19C3.3	T19C3.3	n/a	chrIII 612,715
27	T16G1.4	T16G1.4	n/a	chrV 12,940,921	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
28	C02F4.4	C02F4.4	n/a	chrIV 10,514,479	contains similarity to Listeria monocytogenes Hypothetical protein lmo1466.; TR:Q8Y746
29	str-243	K02H11.7	n/a	chrV 1,523,505	C. elegans STR-243 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	D1005.5	D1005.5	n/a	chrX 1,471,940
31	tag-225	K07C11.5	n/a	chrV 8,202,146	K07C11.5 is orthologous to the human gene SIMILAR TO TISSUE INHIBITOR OF METALLOPROTEINASE 3 (SORSBY FUNDUS DYSTROPHY, PSEUDOINFLAMMATORY) (TIMP3; OMIM:188826), which when mutated leads to disease.
32	F45E1.3	F45E1.3	n/a	chrX 7,987,677	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domain IPR005834 (Haloacid dehalogenase-like hydrolase)
33	glb-22	R11H6.3	n/a	chrV 14,605,162	glb-22 encodes a globin with no obvious function in mass RNAi assays.
34	crn-2	CD4.2	n/a	chrV 5,595,167	crn-2 encodes a cell death-related nuclease, homologous to the magnesium-dependant TatD nuclease of E. coli; CRN-2 is required for normal levels of DNA degradation during apoptosis; crn-2(RNAi) 1.5-fold stage embryos display TUNEL labelling of nuclei that is five-fold higher than that seen in untreated N2 animals; CRN-2 promotes both DNA degradation and cell corpse engulfment, in a partially redundant pathway that includes CRN-3 but is parallel to CPS-6; CRN-2 is predicted to be mitochondrial.
35	C34C6.3	C34C6.3	n/a	chrII 8,692,922	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF07974 (EGF-like domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR000585 (Hemopexin), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR005018 (DOMON related), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular)
36	R13H4.5	R13H4.5	n/a	chrV 11,861,454	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
37	F58H10.1	F58H10.1	n/a	chrI 7,756,062	contains similarity to Homo sapiens Splice isoform Long of Q8WXX7 Autism susceptibility gene 2 protein; ENSEMBL:ENSP00000329863
38	F22F1.2	F22F1.2	n/a	chrX 8,150,103	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
39	H41C03.1	H41C03.1	n/a	chrII 5,855,713	contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
40	F54D12.5	F54D12.5	n/a	chrII 1,370,835	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
41	C32H11.8	C32H11.8	n/a	chrIV 12,934,318	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
42	C45E1.4	C45E1.4	n/a	chrI 3,115,322
43	T22F7.4	T22F7.4	n/a	chrIII 526,147
44	F09C12.6	F09C12.6	n/a	chrII 5,117,137	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
45	C13A10.1	C13A10.1	n/a	chrII 1,353,185
46	F39H12.3	F39H12.3	n/a	chrX 839,898	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) (3), PF02197 (Regulatory subunit of type II PKA R-subunit) contains similarity to Interpro domains IPR003117 (cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta), IPR000048 (IQ calmodulin-binding region)
47	F31E8.1	F31E8.1	n/a	chrII 6,829,225
48	sma-2	ZK370.2	n/a	chrIII 8,753,327	sma-2 encodes, along with sma-3 and sma-4, one of three C. elegans Smad proteins, with SMA-2 and SMA-3 most closely related to receptor-regulated Smads (R-Smads) and SMA-4 more closely related to co-mediator Smads (CoSmads); during development, SMA-2 functions in a TGF-beta signaling pathway to regulate body size and specification of sensory structures in the male tail; a sma-2::gfp reporter is expressed in the pharynx, intestine, and hypodermis.
49	C26B2.7	C26B2.7	n/a	chrIV 8,016,527
50	Y20C6A.1	Y20C6A.1	n/a	chrV 17,374,108	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.