UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srbc-19	C45H4.16	5e-167	chrV 2,165,802	C. elegans SRBC-19 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR002208 (SecY protein)
2	gst-15	F37B1.4	n/a	chrII 13,612,395	C. elegans GST-15 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
3	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
4	srh-169	C49G7.2	n/a	chrV 4,048,582	C. elegans SRH-169 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	M117.3	M117.3	n/a	chrIV 11,823,697	M117.3 can encode a protein with similarity to the C-terminal half of the 14-3-3 proteins PAR-5 and FTT-2, beginning in predicted alpha helix five and continuing through the ends of the proteins; loss of M117.3 activity via large-scale RNAi results in no obvious abnormalities.
6	ZK1307.4	ZK1307.4	n/a	chrII 9,651,306	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
7	C54G6.2	C54G6.2	n/a	chrI 1,007,329	The C54G6.2 gene encodes a homolog of human RP2, which when mutated leads to X-linked retinitis pigmentosa 2 (OMIM:312600).
8	F14F8.8	F14F8.8	n/a	chrV 16,671,873	contains similarity to Saccharomyces cerevisiae Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP; SGD:YHR143W
9	T09B9.2	T09B9.2	n/a	chrX 9,763,139	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter), IPR004745 (Na(+)-dependent inorganic phosphate cotransporter)
10	C01A2.4	C01A2.4	n/a	chrI 13,393,035	contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
11	gpa-6	F48C11.1	n/a	chrX 13,192,522	gpa-6 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that affects response to water-soluble odorants; it is expressed in AWA amphid neurons, the PHB sensory cell, and (at low levels) in ASI amphid neurons.
12	srw-60	T11F1.1	n/a	chrII 2,960,240	C. elegans SRW-60 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
13	srsx-35	F53F8.2	n/a	chrV 20,677,605	C. elegans SRSX-35 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR013305 (ABC transporter, ABCB2), IPR000276 (GPCR, rhodopsin-like)
14	Y69H2.2	Y69H2.2	n/a	chrV 18,632,391	contains similarity to Pfam domains PF00008 (EGF-like domain) (5), PF00858 (Amiloride-sensitive sodium channel) , PF07974 (EGF-like domain) (2)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR001873 (Na+ channel, amiloride-sensitive)
15	ZK742.4	ZK742.4	n/a	chrV 7,810,989	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal)
16	K08F9.3	K08F9.3	n/a	chrV 15,143,291	contains similarity to Pfam domains PF00168 (C2 domain) (3), PF08165 (FerA (NUC095) domain) , PF08150 (FerB (NUC096) domain) contains similarity to Interpro domains IPR012561 (FerB), IPR006614 (Dysferlin, C-terminal), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR012560 (FerA), IPR006613 (Dysferlin, N-terminal), IPR000008 (C2 calcium-dependent membrane targeting)
17	F53B6.6	F53B6.6	n/a	chrI 8,956,012	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
18	dpr-1	R10D12.2	n/a	chrV 13,941,139	dpr-1 encodes a putative nuclear hormone receptor that affects endoderm differentiation and may promote entry into the dauer state and maintenance of the dauer state; expressed in the endoderm lineage and localization appears dependent on growth conditions.
19	str-144	C09H5.5	n/a	chrV 8,071,381	C. elegans STR-144 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	pgp-7	T21E8.2	n/a	chrX 10,867,530	pgp-7 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-7 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-7 activity via RNAi results in no obvious defects, the precise role of PGP-7 in C. elegans development and/or behavior is not yet known; pgp-7 promoter-gfp fusion proteins are expressed in the rays of the adult male tail.
21	C50C3.7	C50C3.7	n/a	chrIII 8,160,210	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domains IPR000300 (Inositol polyphosphate related phosphatase), IPR005135 (Endonuclease/exonuclease/phosphatase)
22	ptc-2	F21H12.4	n/a	chrII 6,084,701	ptc-2 encodes an ortholog of Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome), which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTC-2 is required for normal fat storage; PTC-2 is also required for normal egg osmotic integrity, locomotion, egg laying, and viability in mass RNAi assays.
23	C01G6.9	C01G6.9	n/a	chrII 9,294,851	contains similarity to Plasmodium falciparum SET-domain protein, putative.; TR:Q8IC77
24	set-6	C49F5.2	n/a	chrX 11,972,276	set-6 encodes a putative histone H3 lysine-9 methyltransferase; SET-6 has no non-nematode orthologs, but several paralogs (SET-13, SET-15, SET-19, SET-20, SET-21, and SET-32); neither set-6(tm1611) nor set-6(RNAi) have any obvious phenotypes.
25	amt-3	M195.3	n/a	chrII 8,366,108	amt-3 encodes one of four C. elegans homologs of AMT1 (AT11_ARATH), a high-affinity ammonium transporter from Arabidopsis thaliana; AMT-3 is closely similar to its paralog AMT-2, with somewhat more distant paralogy to AMT-1 and AMT-4.
26	F56D2.5	F56D2.5	n/a	chrIII 5,579,782	contains similarity to Pfam domains PF05773 (RWD domain) , PF01485 (IBR domain) (2)contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR006575 (RWD), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like), IPR002867 (Zinc finger, C6HC-type)
27	cav-2	C56A3.7	n/a	chrV 13,558,462	cav-2 encodes one of two C. elegans proteins related to caveolins, integral transmembrane proteins that are believed to function in regulation of signal transduction and that are the major component of caveolae, specialized lipid rafts found in the plasma membrane of most cell types; as loss of cav-2 function via large-scale RNA-mediated interference (RNAi) screens does not result in any obvious abnormalities, the role of cav-2 in C. elegans development and/or behavior is not yet known; cav-2 mRNA is expressed in eggs and mixed stage populations.
28	spp-19	K04A8.9	n/a	chrV 6,559,648	C. elegans SPP-19 protein; contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)
29	egg-4	T21E3.1	n/a	chrI 3,933,502	C. elegans EGG-4 protein; contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
30	C46C11.3	C46C11.3	n/a	chrX 4,630,409
31	fbxa-156	C06H5.1	n/a	chrV 17,896,012	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
32	nhr-250	ZK488.1	n/a	chrV 613,820	C. elegans NHR-250 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
33	C47E8.3	C47E8.3	n/a	chrV 14,681,957	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
34	sri-10	C54E10.4	n/a	chrV 18,805,260	C. elegans SRI-10 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR016040 (NAD(P)-binding)
35	T24C4.3	T24C4.3	n/a	chrIII 872,071
36	ugt-37	F10D2.6	n/a	chrV 7,143,012	C. elegans UGT-37 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
37	rsr-1	F28D9.1	n/a	chrI 11,179,945	C. elegans RSR-1 protein; contains similarity to Pfam domain PF01480 PWI domain contains similarity to Interpro domains IPR002483 (Splicing factor PWI), IPR000694 (Proline-rich region), IPR005819 (Histone H5), IPR002185 (Dopamine D4 receptor)
38	srz-15	C32H11.2	n/a	chrIV 12,916,637	C. elegans SRZ-15 protein ;
39	nhr-125	R02D1.1	n/a	chrV 4,322,934	C. elegans NHR-125 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
40	F49E8.6	F49E8.6	n/a	chrIV 7,553,994	contains similarity to Interpro domain IPR000694 (Proline-rich region)
41	ZK945.8	ZK945.8	n/a	chrII 10,108,812	contains similarity to Pfam domain PF07491 Protein phosphatase inhibitor contains similarity to Interpro domain IPR011107 (Protein phosphatase inhibitor)
42	T22C8.1	T22C8.1	n/a	chrII 8,613,779	contains similarity to Rattus norvegicus Cysteinyl leukotriene receptor 2 (CysLTR2) (RSBPT32).; SW:CLT2_RAT
43	ZK250.2	ZK250.2	n/a	chrII 1,949,294	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
44	F10D7.1	F10D7.1	n/a	chrX 17,362,183	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
45	F36F12.7	F36F12.7	n/a	chrV 2,099,700
46	F58B3.6	F58B3.6	n/a	chrIV 11,637,391	contains similarity to Pfam domains PF04836 (Interferon-related protein conserved region) , PF05004 (Interferon-related developmental regulator (IFRD)) contains similarity to Interpro domains IPR007701 (Interferon-related developmental regulator), IPR006921 (Interferon-related protein conserved region), IPR016024 (Armadillo-type fold)
47	clec-259	M162.1	n/a	chrV 19,786,034	C. elegans CLEC-259 protein; contains similarity to Pfam domain PF00337 Galactoside-binding lectin contains similarity to Interpro domains IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR007233 (Sybindin-like protein), IPR008985 (Concanavalin A-like lectin/glucanase)
48	atf-6	F45E6.2	n/a	chrX 12,482,840	atf-6 is an ortholog of mammalian ATF6alpha, a proximal sensor required for the unfolded protein response (UPR) in the endoplasmic reticulum (ER); ATF6alpha is a transmembrane protein, with a bZIP transcription factor domain in its cytosolic amino terminus that is released and activated by proteolytic cleavage upon ER stress; either ire-1 or xbp-1 deletions are synthetically lethal with atf-6 or pek-1 deletions, producing arrest in L2 larvae; RNAi of Y56A3A.2 (a S2P protease homolog) is synthetically lethal with ire-1(RNAi), consistent with the hypothesis that Y56A3A.2 cleaves ATF-6; atf-6 regulates few genes that are transcriptionally induced by UPR, but regulates roughly one-quarter of genes that require UPR constitutively; pdr-1 transcripts are strongly upregulated in a atf-6(ok551) mutant background, but atf-6(ok551);pdr-1(lg103) double mutants have a grossly normal phenotype ; atf-6 is dispensable for proper localization of GLR-1 glutamate receptors.
49	C06E4.3	C06E4.3	n/a	chrIV 7,261,440	contains similarity to Pfam domains PF07993 (Male sterility protein) , PF01370 (NAD dependent epimerase/dehydratase family) , PF00106 (short chain dehydrogenase) contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR001509 (NAD-dependent epimerase/dehydratase), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR013120 (Male sterility, NAD-binding)
50	R07E5.5	R07E5.5	n/a	chrIII 4,398,025	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)