UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C44F1.1	C44F1.1	0	chrIII 3,761,814	contains similarity to Interpro domain IPR008967 (p53-like transcription factor, DNA-binding)
2	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
3	D1046.5	D1046.5	n/a	chrIV 8,960,986	contains similarity to Homo sapiens Isoform 1 of Integral membrane protein GPR175; ENSEMBL:ENSP00000347748
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	C01H6.3	C01H6.3	n/a	chrI 7,208,985	contains similarity to Pfam domain PF00096 (Zinc finger, C2H2 type)
6	srd-42	R04D3.7	n/a	chrX 13,302,450	C. elegans SRD-42 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	irk-3	K04G11.5	n/a	chrX 14,356,108	C. elegans IRK-3 protein; contains similarity to Pfam domain PF01007 Inward rectifier potassium channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR014756 (Immunoglobulin E-set), IPR013518 (Potassium channel, inwardly rectifying, Kir, cytoplasmic), IPR001838 (Potassium channel, inwardly rectifying, Kir-like)
8	T10B10.5	T10B10.5	n/a	chrX 15,197,450	contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
9	C38C3.6	C38C3.6	n/a	chrV 1,485,347	contains similarity to Interpro domain IPR000694 (Proline-rich region)
10	srw-20	T05E12.4	n/a	chrV 17,079,045	C. elegans SRW-20 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
11	E03H12.4	E03H12.4	n/a	chrIV 4,982,952	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
12	C30E1.6	C30E1.6	n/a	chrX 16,916,238
13	sru-27	C38C3.2	n/a	chrV 1,500,054	C. elegans SRU-27 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
14	ZK938.3	ZK938.3	n/a	chrII 9,832,928	contains similarity to Pfam domain PF00612 IQ calmodulin-binding motif contains similarity to Interpro domain IPR000048 (IQ calmodulin-binding region)
15	F23F1.3	F23F1.3	n/a	chrII 32,686
16	srbc-6	C36C5.3	n/a	chrV 3,170,772	C. elegans SRBC-6 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
17	ZK1010.6	ZK1010.6	n/a	chrIII 12,989,808	contains similarity to Pfam domain PF01666 DX module contains similarity to Interpro domain IPR002593 (Protein of unknown function DX)
18	T11B7.2	T11B7.2	n/a	chrIV 8,844,038	contains similarity to Homo sapiens remodeling and spacing factor 1; ENSEMBL:ENSP00000311513
19	sru-6	C33A12.8	n/a	chrIV 9,491,282	C. elegans SRU-6 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
20	F22E5.1	F22E5.1	n/a	chrII 2,676,663	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
21	ZC132.9	ZC132.9	n/a	chrV 4,318,616
22	F15D3.4	F15D3.4	n/a	chrI 11,568,010	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
23	F45E6.1	F45E6.1	n/a	chrX 12,476,473	contains similarity to Interpro domain IPR005829 (Sugar transporter, conserved site)
24	nhr-96	F44C8.11	n/a	chrV 2,234,310	nhr-96 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
25	clec-263	F26F2.6	n/a	chrV 20,571,518	C. elegans CLEC-263 protein; contains similarity to Pfam domains PF08277 (PAN-like domain) (2), PF00024 (PAN domain) contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
26	B0244.4	B0244.4	n/a	chrIII 5,749,496	contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR017452 (GPCR, rhodopsin-like superfamily)
27	ift-74	C18H9.8	n/a	chrII 6,681,205	C. elegans IFT-74 protein; contains similarity to Interpro domains IPR010989 (t-SNARE), IPR000694 (Proline-rich region)
28	C08H9.1	C08H9.1	n/a	chrII 9,876,448	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
29	glb-14	F21A3.6	n/a	chrV 15,543,990	glb-14 encodes a globin with no obvious function in mass RNAi assays; glb-14 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-14 is downregulated in a daf-2(e1370) mutant background under normoxic conditions.
30	ire-1	C41C4.4	n/a	chrII 8,118,482	ire-1 encodes a transmembrane serine/threonine protein kinase and site-specific endoribonuclease orthologous to Saccharomyces cerevisiae inositol-requiring 1 protein kinase (Ire1) and human endoplasmic reticulum-to-nucleus signaling 1 (ERN1, OMIM:604033); IRE-1 is required for the unfolded protein response (UPR) that counteracts cellular stress induced by accumulation of unfolded proteins in the endoplasmic reticulum (ER); in response to ER stress, IRE-1 cleaves xbp-1 mRNA to produce transcriptionally active XBP-1 that positively regulates UPR gene expression in order to maintain ER homeostasis.
31	R07C3.3	R07C3.3	n/a	chrII 939,772	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
32	K03B4.6	K03B4.6	n/a	chrV 4,673,573	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domains IPR004920 (Protein of unknown function DUF263), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
33	nhr-132	R11G11.1	n/a	chrV 535,310	C. elegans NHR-132 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
34	fbxa-141	D1025.3	n/a	chrX 14,512,622	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
35	T16A1.4	T16A1.4	n/a	chrII 2,081,787
36	ceh-23	ZK652.5	n/a	chrIII 7,840,469	The ceh-23 gene encodes a homeodomain protein required for a specific differentiated trait of the thermosensory interneuron AIY.
37	B0554.5	B0554.5	n/a	chrV 425,501	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR016196 (MFS general substrate transporter)
38	cyp-34A3	C41G6.1	n/a	chrV 15,229,059	C. elegans CYP-34A3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
39	T20F7.5	T20F7.5	n/a	chrX 16,850,352	contains similarity to Interpro domain IPR000694 (Proline-rich region)
40	puf-9	W06B11.2	n/a	chrX 5,843,741	The puf-9 gene encodes a predicted RNA binding protein orthologous to Drosophila PUMILIO and human PUMILIO 2 (OMIM:607205); PUF-9 is required for normal locomotion and fluid balance, and is expressed primarily in somatic tissues; PUF-9 contains a glutamine/asparagine-rich domain.
41	F28G4.3	F28G4.3	n/a	chrV 16,286,908	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
42	F12A10.5	F12A10.5	n/a	chrII 5,481,296	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
43	ins-32	Y8A9A.6	n/a	chrII 3,803,141	ins-32 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-32 is one of 38 insulin-like peptides in C. elegans and the precise role of INS-32 in C. elegans development is not yet clear as loss of INS-32 function does not result in a mutant phenotype.
44	F38A1.11	F38A1.11	n/a	chrIV 1,248,205	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
45	dpy-22	F47A4.2	n/a	chrX 9,816,134	dpy-22 encodes a broadly expressed protein, homologous to the human transcriptional mediator protein TRAP230, which is involved in WNT and RAS signaling, as well as in dosage compensation; DPY-22 has a C-terminal glutamine-rich domain that is dispensable for inhibition of RAS-dependent cell differentiation, but is required for inhibition of BAR-1-dependent gene expression.
46	glb-8	C26C6.7	n/a	chrI 7,510,602	glb-8 encodes a globin with no obvious function in mass RNAi assays; glb-8 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-8 expression is downregulated in a daf-2(e1370) mutant background under normoxic conditions; glb-8 expression is lower in L3 larvae than in young adults or dauers.
47	C39B10.5	C39B10.5	n/a	chrX 10,447,468	contains similarity to Saccharomyces cerevisiae bZIP protein; transcription factor; SGD:YIR018W
48	Y39A3B.3	Y39A3B.3	n/a	chrIII 1,986,275
49	F56C3.9	F56C3.9	n/a	chrX 1,392,907	contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013089 (Kelch related)
50	T14C1.1	T14C1.1	n/a	chrX 14,408,600	T14C1.1 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that T14C1.1 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).