UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C44B7.7	C44B7.7	2e-108	chrII 6,879,653	contains similarity to Homo sapiens Uncharacterized protein C7orf24; ENSEMBL:ENSP00000275428
2	T19D12.1	T19D12.1	n/a	chrII 6,670,282	contains similarity to Drosophila melanogaster Flybase gene name is Sgs1-PA;; FLYBASE:CG3047
3	F25B4.6	F25B4.6	n/a	chrV 5,683,638	F25B4.6 is orthologous to the human gene 3-HYDROXY-3-METHYLGLUTARYL COA SYNTHASE (HMGCS2; OMIM:600234), which when mutated leads to disease.
4	T25D3.2	T25D3.2	n/a	chrII 155,462	contains similarity to Mus musculus 39S ribosomal protein L28, mitochondrial precursor (L28mt) (MRP-L28).; SW:Q9D1B9
5	W03F9.10	W03F9.10	n/a	chrV 129,988	contains similarity to Pfam domains PF04046 (PSP) , PF04037 (Domain of unknown function (DUF382)) contains similarity to Interpro domains IPR006568 (PSP, proline-rich), IPR007180 (Protein of unknown function DUF382)
6	K08F11.5	K08F11.5	n/a	chrIV 4,714,405	contains similarity to Pfam domains PF08356 (EF hand associated) , PF08355 (EF hand associated) , PF00071 (Ras family) , PF00036 (EF hand) (2), PF08477 (Miro-like protein) (2)contains similarity to Interpro domains IPR013566 (EF hand associated, type-1), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily), IPR013567 (EF hand associated, type-2)
7	B0334.5	B0334.5	n/a	chrII 11,498,118	contains similarity to Interpro domain IPR008949 (Terpenoid synthase)
8	dap-3	C14A4.2	n/a	chrII 10,581,748	dap-3 is an ortholog of mammalian death-associated protein 3 (DAP3), a mitochondrial ribosomal protein that promotes apoptosis.
9	dct-18	F58G1.4	n/a	chrII 12,932,607	C. elegans DCT-18 protein; contains similarity to Interpro domain IPR000886 (Endoplasmic reticulum, targeting sequence)
10	W09D10.3	W09D10.3	n/a	chrIII 10,708,021	contains similarity to Pfam domain PF00542 Ribosomal protein L7/L12 C-terminal domain contains similarity to Interpro domains IPR013823 (Ribosomal protein L7/L12, C-terminal), IPR014719 (Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like), IPR008932 (Ribosomal protein L7/L12, oligomerisation)
11	aqp-11	ZK525.2	n/a	chrIII 13,673,891	aqp-11 encodes a putative aquaporin with no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-9 and AQP-10; AQP-11 is orthologous to Drosophila CG12251 and human AQP11 (OMIM:609914), AQP12A (OMIM:609789), and AQP12B.
12	eft-1	ZK328.2	n/a	chrIII 6,011,147	eft-1 encodes an elongation factor 2 (EF-2)-like protein; by homology, EFT-1 is predicted to function as a GTPase required for the elongation step of protein synthesis; loss of eft-1 activity via large-scale RNAi indicates that eft-1 is an essential gene required for embryonic development, reproduction, and the overall health of the animal; eft-1 mRNA is detectable at all stages of C. elegans development.
13	acl-8	T05H4.1	n/a	chrV 6,451,547	C. elegans ACL-8 protein; contains similarity to Pfam domain PF01553 Acyltransferase contains similarity to Interpro domain IPR002123 (Phospholipid/glycerol acyltransferase)
14	erv-46	K09E9.2	n/a	chrX 15,615,388	C. elegans ERV-46 protein; contains similarity to Pfam domain PF07970 Protein of unknown function (DUF1692) contains similarity to Interpro domain IPR012936 (Protein of unknown function DUF1692)
15	Y113G7B.16	Y113G7B.16	n/a	chrV 20,268,307	contains similarity to Pfam domain PF05600 Protein of unknown function (DUF773) contains similarity to Interpro domain IPR008491 (Protein of unknown function DUF773)
16	tag-231	ZK430.2	n/a	chrII 4,421,285	C. elegans TAG-231 protein; contains similarity to Pfam domain PF00459 Inositol monophosphatase family contains similarity to Interpro domains IPR000760 (Inositol monophosphatase), IPR000146 (Inositol phosphatase/fructose-1,6-bisphosphatase)
17	H19N07.1	H19N07.1	n/a	chrV 11,111,736	contains similarity to Pfam domains PF03143 (Elongation factor Tu C-terminal domain) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) contains similarity to Interpro domains IPR000795 (Protein synthesis factor, GTP-binding), IPR004160 (Translation elongation factor EFTu/EF1A, C-terminal), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR009001 (Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)
18	C29F7.2	C29F7.2	n/a	chrX 13,417,071	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
19	abu-8	C03A7.14	n/a	chrV 5,193,784	abu-8 encodes a transmembrane protein with a predicted signal sequence, a glutamine/asparagine-rich domain and multiple cysteine-rich repeats (DUF139); abu-8 expression is induced by blockage of the unfolded-protein response in the endoplasmic reticulum, and ABU-8 may help protect the organism from damage by improperly folded nascent protein.
20	K06A5.6	K06A5.6	n/a	chrI 6,465,004	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02771 (Acyl-CoA dehydrogenase, N-terminal domain) contains similarity to Interpro domains IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR006089 (Acyl-CoA dehydrogenase, conserved site), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR006092 (Acyl-CoA dehydrogenase, N-terminal)
21	F23C8.5	F23C8.5	n/a	chrI 2,419,472	The F23C8.5 gene encodes an ortholog of the human gene ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT (ETFB), which when mutated leads to glutaricaciduria type IIB (OMIM:130410).
22	K11B4.1	K11B4.1	n/a	chrI 14,796,015	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
23	pfd-3	T06G6.9	n/a	chrI 12,729,010	pfd-3 encodes a putative prefoldin, orthologous to human VBP1 (OMIM:300133), that is required for normal alpha-tubulin synthesis, microtubule growth, mitotic spindle formation and positioning, early embryonic cell division, and embryonic and larval viability; PFD-3 is expressed cytoplasmically in most, if not all, tissues.
24	F11C1.3	F11C1.3	n/a	chrX 12,983,754	contains similarity to Pfam domain PF01130 CD36 family contains similarity to Interpro domain IPR002159 (CD36 antigen)
25	spt-5	K08E4.1	n/a	chrIV 12,053,606	C. elegans SPT-5 protein; contains similarity to Pfam domains PF03439 (Supt5 repeat) (2), PF00467 (KOW motif) contains similarity to Interpro domains IPR005100 (Supt5 repeat), IPR008991 (Translation protein SH3-like), IPR003257 (Transcription antitermination protein, NusG, archaea), IPR005824 (KOW), IPR017071 (Transcription elongation factor Spt5), IPR006645 (Transcription antitermination protein, NusG, N-terminal)
26	E04A4.5	E04A4.5	n/a	chrIV 4,744,928	contains similarity to Pfam domain PF02466 Tim17/Tim22/Tim23 family contains similarity to Interpro domains IPR005678 (Mitochondrial import inner membrane translocase, subunit Tim17), IPR003397 (Mitochondrial import inner membrane translocase, subunit Tim17/22)
27	T08B1.1	T08B1.1	n/a	chrV 1,984,861	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR000817 (Prion protein), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
28	ugt-21	C33A12.6	n/a	chrIV 9,501,385	C. elegans UGT-21 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
29	gstk-1	ZK1320.1	n/a	chrII 9,657,127	C. elegans GSTK-1 protein; contains similarity to Pfam domain PF01323 DSBA-like thioredoxin domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR001853 (DSBA oxidoreductase), IPR014440 (HCCA isomerase/glutathione S-transferase kappa)
30	nid-1	F54F3.1	n/a	chrV 12,913,630	C. elegans NID-1 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (3), PF07645 (Calcium binding EGF domain) , PF06119 (Nidogen-like) , PF07474 (G2F domain) , PF01436 (NHL repeat) (2), PF00058 (Low-density lipoprotein receptor repeat class B) (4)contains similarity to Interpro domains IPR000033 (), IPR011061 (Proteinase inhibitor I14/I15, hirudin/antistatin), IPR000742 (EGF-like, type 3), IPR009017 (Green fluorescent protein-like), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR003886 (Nidogen, extracellular region), IPR003944 (Protease-activated receptor 4), IPR001881 (EGF-like calcium-binding), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013032 (EGF-like region, conserved site), IPR006605 (G2 nidogen and fibulin G2F), IPR013091 (EGF calcium-binding), IPR015943 (WD40/YVTN repeat-like)
31	C23G10.8	C23G10.8	n/a	chrIII 6,204,357	contains similarity to Homo sapiens Conserved hypothetical protein; VG:OTTHUMP00000076919
32	daf-36	C12D8.5	n/a	chrV 10,224,591	daf-36 encodes a protein homologous to the catalytic subunit of Rieske-like oxygenases; DAF-36 functions in a hormone biosynthetic pathway producing a ligand for the DAF-12 nuclear receptor that regulates the developmental decision between reproductive growth and dauer formation; a daf-36::gfp reporter fusion is expressed in the intestine, the head mesodermal cell, two unidentified head neurons (not XXXR/L) and, in dauers, the lateral seam cells; DAF-36 localizes to the cytoplasm in the intestine and to a cytosolic meshwork in dauer seam cells.
33	alh-9	F01F1.6	n/a	chrIII 5,858,031	C. elegans ALH-9 protein; contains similarity to Pfam domain PF00171 Aldehyde dehydrogenase family contains similarity to Interpro domains IPR016163 (Aldehyde dehydrogenase, C-terminal), IPR016162 (Aldehyde dehydrogenase, N-terminal), IPR016161 (Aldehyde/histidinol dehydrogenase), IPR015590 (Aldehyde dehydrogenase), IPR016160 (Aldehyde dehydrogenase, conserved site)
34	T02G5.4	T02G5.4	n/a	chrII 7,083,184	contains similarity to Pfam domains PF02803 (Thiolase, C-terminal domain) , PF00108 (Thiolase, N-terminal domain) contains similarity to Interpro domains IPR016038 (Thiolase-like, subgroup), IPR002155 (Thiolase), IPR016039 (Thiolase-like)
35	K06A4.5	K06A4.5	n/a	chrV 9,506,309	contains similarity to Pfam domain PF06052 3-hydroxyanthranilic acid dioxygenase contains similarity to Interpro domains IPR011051 (Cupin, RmlC-type), IPR016700 (3-hydroxyanthranilate 3, 4-dioxygenase, metazoan), IPR010329 (3-hydroxyanthranilic acid dioxygenase)
36	C06A8.3	C06A8.3	n/a	chrII 7,790,994	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
37	arl-1	F54C9.10	n/a	chrII 8,582,264	arl-1 encodes a member of the GTP-binding ADP-ribosylation factor family.
38	pqn-47	F59B10.1	n/a	chrII 10,499,684	pqn-47 encodes a protein with a glutamine/asparagine-rich domain, homologous to human C11orf9 and Drosophila CG3328, that is required for locomotion, vulval development, full body size, cuticular integrity, and general health in mass RNAi assays; pqn-47(cxP5915) homozygotes are sluggish.
39	C03H12.1	C03H12.1	n/a	chrX 15,692,830	contains similarity to Interpro domain IPR012336 (Thioredoxin-like fold)
40	F36A2.3	F36A2.3	n/a	chrI 8,800,214	contains similarity to Pfam domain PF02615 Malate/L-lactate dehydrogenase contains similarity to Interpro domain IPR003767 (Malate/L-lactate dehydrogenase)
41	sur-5	K03A1.5	n/a	chrX 7,303,412	sur-5 encodes a protein with high similarity to H. sapiens Acetoacetyl-coenzyme A synthetase; sur-5 negatively regulates let-60 during vulval induction, based on genetic analysis, and genetically synergises with lin-45 with respect to larval death, uncoordinated movement and egg-laying defects; sur-5 is strongly expressed in most cells of C. elegans, including the VPCs and is localized primarily to the nucleus.
42	ZK1098.7	ZK1098.7	n/a	chrIII 9,523,311	contains similarity to Drosophila melanogaster Flybase gene name is mRpS23-PA;; FLYBASE:CG31842
43	C08H9.2	C08H9.2	n/a	chrII 9,888,735	contains similarity to Pfam domain PF00013 KH domain contains similarity to Interpro domains IPR004087 (K Homology), IPR004088 (K Homology, type 1)
44	xpo-3	C49H3.10	n/a	chrIV 7,920,396	imb-6 encodes an importin-beta-like protein orthologous to vertebrate Exportin-t, a specific mediator of tRNA export from the nucleus; IMB-6 is predicted to function by binding tRNAs directly in the presence of the RAN-1 GTPase and facilitating their nucleocytoplasmic transport; in C. elegans, loss of imb-6 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities.
45	cyp-35C1	C06B3.3	n/a	chrV 13,897,551	C. elegans CYP-35C1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
46	nhr-68	H12C20.3	n/a	chrV 11,574,552	C. elegans NHR-68 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
47	folt-2	F37B4.7	n/a	chrV 2,874,024	folt-2 encodes a putative folate transporter; FOLT-2 is orthologous to human SLC19A1 (OMIM:600424), SLC19A2 (OMIM:603941, mutated in thiamine-responsive megaloblastic anemia syndrome), and SLC19A3 (OMIM:606152, mutated in biotin-responsive basal ganglia disease); heterologously expressed FOLT-2 does not significantly transport folate; FOLT-2 has no obvious function in mass RNAi assays, perhaps because of genetic redundancy with its paralogs FOLT-1 and FOLT-3.
48	C05D11.1	C05D11.1	n/a	chrIII 6,438,225	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
49	dnj-11	F38A5.13	n/a	chrIV 6,587,011	This gene encodes a protein containing a DnaJ ('J') domain.
50	rad-23	ZK20.3	n/a	chrII 11,652,044	C. elegans RAD-23 protein; contains similarity to Pfam domains PF09280 (XPC-binding domain) , PF00627 (UBA/TS-N domain) (2), PF00240 (Ubiquitin family) contains similarity to Interpro domains IPR004806 (UV excision repair protein Rad23), IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000104 (Antifreeze protein, type I), IPR014761 (UV excision repair protein Rad23, C-terminal), IPR000626 (Ubiquitin), IPR009060 (UBA-like), IPR006636 (Heat shock chaperonin-binding), IPR000449 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote), IPR015360 (XPC-binding domain)