UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C44B7.4	C44B7.4	0	chrII 6,869,836	contains similarity to Rattus norvegicus Protein FAM26F.; SW:Q561R8
2	R13.4	R13.4	n/a	chrIV 10,819,150	contains similarity to Pfam domain PF02891 MIZ/SP-RING zinc finger contains similarity to Interpro domain IPR004181 (Zinc finger, MIZ-type)
3	T08B1.6	T08B1.6	n/a	chrV 1,971,994	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
4	T05A1.3	T05A1.3	n/a	chrIV 9,563,673	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
5	rpl-42	C09H10.1	n/a	chrII 11,093,225	C. elegans RPL-42 protein ;
6	ceh-6	K02B12.1	n/a	chrI 8,500,257	ceh-6 encodes a POU family homeodomain protein, homologous to human POU3F4 (OMIM:304400, mutated in conductive deafness 3) that affects embryonic viability, locomotion, and molting, and that regulates ectodermal and excretory function; CEH-6 is expressed dynamically during development and expression includes neurons, the excretory cell, and ectodermal cells.
7	ZK418.6	ZK418.6	n/a	chrIII 7,076,490	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000694 (Proline-rich region), IPR000276 (GPCR, rhodopsin-like)
8	T23G4.4	T23G4.4	n/a	chrIV 13,675,781	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
9	glb-23	R13A1.8	n/a	chrIV 7,218,772	glb-23 encodes a globin; glb-23 transcription is higher in L3 and dauers than in young adults; glb-23 has no obvious function in mass RNAi assays.
10	Y113G7B.15	Y113G7B.15	n/a	chrV 20,226,741	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
11	T01B6.1	T01B6.1	n/a	chrX 2,342,147	n/a
12	srx-90	H12C20.5	n/a	chrV 11,581,770	C. elegans SRX-90 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
13	cst-2	C24A8.4	n/a	chrX 4,334,568	C. elegans CST-2 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
14	ndx-1	T26E3.2	n/a	chrI 12,680,484	The ndx-1 gene encodes a NUDIX hydrolase.
15	T05C7.1	T05C7.1	n/a	chrIV 48,261	contains similarity to Interpro domain IPR011019 (KIND)
16	C04F6.2	C04F6.2	n/a	chrX 3,397,298
17	C33E10.6	C33E10.6	n/a	chrX 17,268,242	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q227I5
18	B0207.11	B0207.11	n/a	chrI 5,963,581	B0207.11 encodes a nematode-specific protein probably required for a normally high ovulation rate; B0207.11 has no obvious non-nematode homologs, but does have a putative N-terminal coiled-coil domain and an SH2 motif, and is is paralogous to four other C. elegans proteins (F42G4.6, F44F4.10, T08G11.2, and Y81G3A.1); B0207.11(tm322) hermaphrodites show abnormal egg-laying, retaining significantly fewer eggs than wild-type (perhaps due to a lowered ovulation rate) while retaining late-stage embryos; B0207.11 has no obvious phenotype in mass RNAi experiments, possibly because of genetic redundancy with its paralogs.
19	F07C3.3	F07C3.3	n/a	chrV 9,230,874	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
20	spe-19	Y113G7A.10	n/a	chrV 20,039,581	C. elegans SPE-19 protein ;
21	nhr-7	F54D1.4	n/a	chrIV 11,267,544	C. elegans NHR-7 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000694 (Proline-rich region), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
22	C45G9.11	C45G9.11	n/a	chrIII 5,066,320
23	rbc-1	F54E4.1	n/a	chrX 14,617,784	rbc-1 encodes an ortholog of S. cerevisiae RAV1; like RAV1, RBC-1 may be required for the reassociation of vacuolar proton-translocating ATPase (V-ATPase) after temporary glucose starvation.
24	trpa-1	C29E6.2	n/a	chrIV 11,870,347	trpa-1 encodes a transient receptor potential (TRP) ion channel orthologous to the vertebrate and Drosophila TRPA1 channels; in C. elegans, trpa-1 activity is required for specific mechanosensory behaviors such as nose-touch avoidance and touch-mediated foraging; when expressed in mammalian cells, TRPA-1 exhibits channel activity in response to mechanical stimulation; TRPA-1::GFP reporters are expressed in a number of different cell types including sensory neurons, muscle, and epithelial cells.
25	fbxa-223	ZC513.10	n/a	chrV 8,064,176	fbxa-223 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXA-223 also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
26	hum-7	F56A6.2	n/a	chrI 596,704	hum-7 encodes a class IX unconventional myosin heavy chain that contains a myosin motor domain in the head region and zinc-finger and rhoGAP (rho GTPase activating protein) domains in the tail region; HUM-7 is required during embryogenesis for cytokinesis and normal cytoplasmic rearrangements, and by homology, may function in organization of the actin cytoskeleton; the precise expression and localization patterns of HUM-7 are not yet known.
27	nfyb-1	W10D9.4	n/a	chrII 464,524	C. elegans NFYB-1 protein; contains similarity to Pfam domain PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone contains similarity to Interpro domains IPR009072 (Histone-fold), IPR003957 (Transcription factor, CBFA/NFYB, DNA topoisomerase), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
28	T06G6.4	T06G6.4	n/a	chrI 12,713,797	contains similarity to Arabidopsis thaliana Synaptonemal complex protein 1 (Synaptonemal complex central regionsprotein ZYP1a).; SW:Q9LME2
29	C54G4.2	C54G4.2	n/a	chrI 8,007,875	contains similarity to Saccharomyces cerevisiae protein of unknown function; SGD:YNR051C
30	C34G6.3	C34G6.3	n/a	chrI 5,897,020	contains similarity to Interpro domain IPR005819 (Histone H5)
31	F21C3.6	F21C3.6	n/a	chrI 7,284,859	contains similarity to Homo sapiens Isoform 1 of Caldesmon; ENSEMBL:ENSP00000354826
32	Y47H9B.2	Y47H9B.2	n/a	chrI 11,745,783	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
33	Y7A5A.8	Y7A5A.8	n/a	chrX 15,823,201	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IL30
34	K02H11.6	K02H11.6	n/a	chrV 1,534,154	contains similarity to Pfam domains PF00085 (Thioredoxin) , PF08534 (Redoxin) , PF00578 (AhpC/TSA family) contains similarity to Interpro domains IPR011594 (Thioredoxin-like), IPR013740 (Redoxin), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR000866 (Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related)
35	ZC404.7	ZC404.7	n/a	chrV 6,779,108
36	F34D10.6	F34D10.6	n/a	chrIII 3,756,086	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
37	unc-29	T08G11.5	n/a	chrI 8,899,525	unc-29 encodes an non-alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; UNC-29 is required for normal locomotion and egg-laying, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with LEV-1, a non-alpha nAChR subunit, and UNC-38 or UNC-63, alpha AChR subunits, the resulting multimer can form levamisole-gated channels; UNC-29 is expressed in body wall muscle.
38	C12D5.9	C12D5.9	n/a	chrV 7,689,147	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
39	K07D4.6	K07D4.6	n/a	chrII 4,017,758	contains similarity to Drosophila melanogaster Flybase gene name is CG31439-PA;; FLYBASE:CG31439
40	T06C12.9	T06C12.9	n/a	chrV 15,885,834	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
41	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
42	W05B5.1	W05B5.1	n/a	chrI 13,043,893	contains similarity to Saccharomyces cerevisiae Homolog of human WASP, proline-rich protein; SGD:YOR181W
43	W04E12.5	W04E12.5	n/a	chrV 19,742,714	contains similarity to Interpro domain IPR000750 (Proenkephalin B)
44	F25E5.2	F25E5.2	n/a	chrV 7,456,619	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
45	Y113G7B.11	Y113G7B.11	n/a	chrV 20,209,977	contains similarity to Naja atra Cardiotoxin 10 precursor.; TR:Q9W6W6
46	K08D10.9	K08D10.9	n/a	chrIV 4,159,983
47	C29F9.5	C29F9.5	n/a	chrIII 118,236	contains similarity to Pfam domain PF02135 TAZ zinc finger contains similarity to Interpro domains IPR003101 (Coactivator CBP, KIX), IPR000197 (Zinc finger, TAZ-type)
48	C31H1.2	C31H1.2	n/a	chrIV 5,792,361	contains similarity to Pfam domain PF02013 Cellulose or protein binding domain contains similarity to Interpro domains IPR003616 (Post-SET zinc-binding region), IPR000215 (Protease inhibitor I4, serpin), IPR002883 (Dockerin, cellulose-binding family V)
49	C03B1.6	C03B1.6	n/a	chrX 6,350,637
50	K02H8.1	K02H8.1	n/a	chrX 17,004,963	K02H8.1 encodes, by alternative splicing, two isoforms of a putative MUSCLEBLIND-type mRNA splicing regulator required in adults for normal muscle dense body organization, locomotion, and vulval morphogenesis; K02H8.1 is orthologous to Drosophila MBL and human MBNL1 (OMIM:606516), MBNL2 (OMIM:607327), and MBNL3 (OMIM:300413); K02H8.1 is transcribed in larvae and adults; K02H8.1(RNAi) animals show protruding vulvae, progressive uncoordination, and disordered dense bodies; while K02H8.1 is required in adults, it is dispensable in larvae, perhaps reflecting a progressive muscle dystrophy in K02H8.1(RNAi) animals.