UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C43H8.2	C43H8.2	2.9999999999999998e-142	chrI 10,623,645	contains similarity to Pfam domain PF09174 Maf1 regulator contains similarity to Interpro domains IPR017152 (RNA polymerase III transcriptional repressor, MAF1), IPR015257 (Maf1 regulator)
2	Y106G6H.15	Y106G6H.15	n/a	chrI 10,473,965	contains similarity to Pfam domain PF07160 Protein of unknown function (DUF1395) contains similarity to Interpro domain IPR009829 (Protein of unknown function DUF1395)
3	B0511.2	B0511.2	n/a	chrI 10,651,985	contains similarity to Interpro domain IPR015804 (Cysteinyl-tRNA synthetase, class Ia, C-terminal)
4	C17E4.6	C17E4.6	n/a	chrI 9,426,826	contains similarity to Pfam domains PF05764 (YL1 nuclear protein) , PF08265 (YL1 nuclear protein C-terminal domain) contains similarity to Interpro domains IPR013272 (YL1 nuclear, C-terminal), IPR008895 (YL1 nuclear)
5	nhr-59	T27B7.1	n/a	chrV 2,277,137	C. elegans NHR-59 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
6	R05F9.9	R05F9.9	n/a	chrII 4,900,966
7	cic-1	H14E04.5	n/a	chrIII 2,397,836	C. elegans CIC-1 protein; contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR015429 (Transcription regulator cyclin)
8	C37C3.1	C37C3.1	n/a	chrV 7,858,917	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domains IPR012816 (Conserved hypothetical protein CHP02464), IPR005448 (Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)
9	hda-2	C08B11.2	n/a	chrII 8,021,602	hda-2 encodes a Class I histone deacetylase; by homology, HDA-2 is predicted to function in deacetylation of histone residues and transcriptional regulation; loss of hda-2 activity via RNAi results in an increased spontaneous mutation rate, suggesting that hda-2 also plays a role in regulating genome stability.
10	srz-94	F49H6.11	n/a	chrV 17,034,553	C. elegans SRZ-94 protein ;
11	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
12	hcf-1	C46A5.9	n/a	chrIV 7,772,495	C. elegans HCF-1 protein; contains similarity to Pfam domains PF01344 (Kelch motif) (3), PF00041 (Fibronectin type III domain) , PF07646 (Kelch motif) (4)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015915 (Kelch-type beta propeller)
13	F54D12.4	F54D12.4	n/a	chrII 1,368,200
14	nud-2	R11A5.2	n/a	chrI 7,858,613	nud-2 encodes an ortholog of human NDE1 (OMIM:609449) and NDEL1 (OMIM:607538), effectors of LIS1 (OMIM:601545); NUD-2, along with other orthologs of LIS1-associated proteins (NUD-1, DHC-1, CDK-5, and CDKA-1), is required to prevent convulsions induced by exposure to the GABA antagonist pentylenetetrazole (PTZ); nud-2(RNAi), like RNAi of nud-1 et al., not only induces PTZ susceptibility but also causes GABA-containing synaptic vesicles in the ventral nerve cord to be distributed raggedly, and nud-2(RNAi) animals are abnormally susceptible to paralysis by the GABA agonist muscimol; nud-2(RNAi) phenotypes are dominantly enhanced by a heterozygous lis-1 allele, and nud-2(RNAi) delays the recovery from PTZ-induced paralysis of lis-1 heterozygotes.
15	dnj-23	T24H10.3	n/a	chrII 9,107,885	This gene encodes a protein containing a DnaJ ('J') domain.
16	B0281.8	B0281.8	n/a	chrII 2,312,169	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
17	fbxb-78	E04A4.1	n/a	chrIV 4,738,137	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
18	agt-2	F09E5.13	n/a	chrII 5,372,696	agt-2 encodes a paralog of the DNA repair enzyme O6-Alkylguanine DNA-alkyltransferase (AGT); AGT-2 has AGT biochemical activity and is expressed at all developmental stages.
19	R11A5.3	R11A5.3	n/a	chrI 7,863,191	contains similarity to Mycobacterium tuberculosis DNA-binding protein HU homolog (Histone-like protein) (Hlp) (21-kDaslaminin-2-binding protein).; SW:DBH_MYCTU
20	hda-3	R06C1.1	n/a	chrI 11,915,408	hda-3 encodes a member of the histone deacetylase family most similar to human histone deacetylase 1 (HD1) that affects radiation sensitivity.
21	C49D10.10	C49D10.10	n/a	chrII 3,875,377	C49D10.10 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C49D10.10 has no clear orthologs in other organisms.
22	C14A4.11	C14A4.11	n/a	chrII 10,606,420	contains similarity to Pfam domain PF06840 Protein of unknown function (DUF1241) contains similarity to Interpro domain IPR009652 (Protein of unknown function DUF1241)
23	C04H5.1	C04H5.1	n/a	chrII 14,534,610	contains similarity to Pfam domain PF03966 Trm112p-like protein contains similarity to Interpro domain IPR005651 (Protein of unknown function DUF343)
24	C14C11.4	C14C11.4	n/a	chrV 5,649,282	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
25	mcm-3	C25D7.6	n/a	chrV 15,058,134	mcm-3 encodes a member of the MCM2/3/5 family with similarity to human DNA replication licensing factor, MCM3, and affects embryonic viability.
26	T23B12.1	T23B12.1	n/a	chrV 8,469,517	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
27	F37B4.10	F37B4.10	n/a	chrV 2,876,718	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
28	VH15N14R.1	VH15N14R.1	n/a	chrI 7,781,895	contains similarity to Aspergillus niger Protein kinase C-like (EC 2.7.1.-).; SW:KPC1_ASPNG
29	M151.4	M151.4	n/a	chrII 3,625,534	contains similarity to Interpro domain IPR000533 (Tropomyosin)
30	C26D10.3	C26D10.3	n/a	chrII 8,327,460	contains similarity to Pfam domain PF07992 Pyridine nucleotide-disulphide oxidoreductase contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000759 (Adrenodoxin reductase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
31	K09A11.1	K09A11.1	n/a	chrX 13,263,425	contains similarity to Pfam domains PF05699 (hAT family dimerisation domain) , PF02892 (BED zinc finger) contains similarity to Interpro domains IPR008906 (HAT dimerisation), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
32	sri-63	F39E9.3	n/a	chrII 3,288,198	C. elegans SRI-63 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003544 (Cytochrome c-type biogenesis protein CcmB)
33	T16H12.2	T16H12.2	n/a	chrIII 10,086,574	contains similarity to Mus musculus 2310010I16Rik protein.; TR:Q9CWH8
34	Y57G7A.2	Y57G7A.2	n/a	chrII 1,296,418
35	Y54G11A.11	Y54G11A.11	n/a	chrII 14,350,230	contains similarity to Pfam domain PF05129 Transcription elongation factor Elf1 like contains similarity to Interpro domain IPR007808 (Protein of unknown function DUF701, zinc-binding putative)
36	C39E9.11	C39E9.11	n/a	chrIV 13,092,485	C39E9.11 is orthologous to the human gene PAPILLARY RENAL CELL CARCINOMA (TRANSLOCATION-ASSOCIATED) (PRCC; OMIM:179755), which when mutated leads to disease.
37	ceh-5	C16C2.1	n/a	chrI 9,727,604	ceh-5 encodes a homeodomain protein, similar to the human VENTRAL ANTERIOR HOMEO BOX 2 gene (VAX2; OMIM:604295); CEH-5 is dispensable for viability and gross morphology.
38	lin-46	R186.4	n/a	chrV 12,969,772	lin-46 encodes one of two C. elegans paralogs of bacterial MoeA proteins and mammalian gephyrins (E domain, only); LIN-46 is predicted to function as a scaffolding protein for a developmental timing complex, and may also play a role in molybdenum cofactor biosynthesis; identified in screens for suppressors of precocious heterochronic mutations in lin-14 and lin-28, lin-46 is required for stage-specific developmental events at the third larval and adult stages of development; as a component of the heterochronic pathway, lin-46 appears to act immediately downstream of lin-28, which encodes a predicted RNA binding protein required for cell fate specification at the L2 stage; a LIN-46:GFP fusion protein is detected in the cytoplasm and non-nucleolar part of the nucleus of ventral and lateral hypodermal cells around the time of the larval molts; in addition, the LIN-46 fusion protein is detected in cell bodies and axons of the AVBL/R motor interneurons.
39	spr-5	Y40B1B.6	n/a	chrI 13,443,987	spr-5 encodes the C. elegans ortholog of the human histone demethylase LSD1 (lysine-specific demethylase 1) that functions to mediate chromatin remodeling and transcriptional regulation; loss of spr-5 activity can suppress the egg-laying defective (Egl) phenotype of mutations in sel-12/presenilin and derepresses expression of hop-1, which encodes the second C. elegans presenilin, by 20- to 30-fold; in binding assays and yeast two-hybrid experiments, SPR-5 interacts with SPR-1, the C. elegans ortholog of CoREST.
40	F10E9.7	F10E9.7	n/a	chrIII 8,306,002	contains similarity to Interpro domain IPR016193 (Cytidine deaminase-like)
41	grl-18	T05C3.4	n/a	chrV 5,487,265	grl-18 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
42	F39H11.1	F39H11.1	n/a	chrI 8,697,062	contains similarity to Pfam domain PF07572 Bucentaur or craniofacial development contains similarity to Interpro domains IPR011421 (Bucentaur or craniofacial development), IPR005413 (Low calcium response V antigen)
43	C25G6.1	C25G6.1	n/a	chrX 1,271,143	contains similarity to Pfam domain PF03803 Scramblase contains similarity to Interpro domain IPR005552 (Scramblase)
44	W01G7.4	W01G7.4	n/a	chrII 14,061,584	contains similarity to Danio rerio Protein SLC7A6OS (Solute carrier family 7 member 6 opposite strandstranscript homolog).; SW:Q5U3I2
45	T08E11.5	T08E11.5	n/a	chrII 1,822,035
46	pstk-1	Y49E10.22	n/a	chrIII 12,467,328	C. elegans PSTK-1 protein; contains similarity to Pfam domain PF08433 Chromatin associated protein KTI12 contains similarity to Interpro domain IPR013641 (Chromatin associated protein KTI12)
47	K03B8.4	K03B8.4	n/a	chrV 11,394,932	contains similarity to Homo sapiens Isoform 2 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; ENSEMBL:ENSP00000349254
48	T11B7.1	T11B7.1	n/a	chrIV 8,841,747	contains similarity to Mus musculus Girdin (Girders of actin filament) (Coiled-coil domain-containingsprotein 88A) (Akt phosphorylation enhancer) (APE) (Hook-relatedsprotein 1) (HkRP1) (G alpha-interacting vesicle-associated protein)s(GIV).; SW:Q5SNZ0
49	srh-239	T26H5.3	n/a	chrV 15,446,542	C. elegans SRH-239 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	M199.2	M199.2	n/a	chrIV 15,109,806	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)