UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C42C1.7	C42C1.7	0	chrIV 12,297,231	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	lin-12	R107.8	n/a	chrIII 9,065,726	The lin-12 gene encodes a member of the Notch/LIN-12/glp-1 transmembrane receptor family that affects cell fate specification events during development, notably including the anchor cell, secondary vulval precursor cells, and the embryonic ABplp lineage; its expression is dynamic, including Z1.ppp and Z4.aaa, ABplaa descendants, ABplpa descendants, and the intestinal primordium.
4	VT23B5.2	VT23B5.2	n/a	chrIV 12,671,338	VT23B5.2 encodes a BEACH-WD40 domain-containing protein that is orthologous to human WDFY3 (WD repeat and FYVE domain containing 3); loss of VT23B5.2 activity via mutation or large-scale RNAi screens in a wild-type background results in no obvious abnormalities.
5	srg-25	T09D3.5	n/a	chrV 5,343,042	C. elegans SRG-25 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
6	C44B9.1	C44B9.1	n/a	chrIII 10,871,842	contains similarity to Interpro domains IPR008162 (Inorganic pyrophosphatase), IPR001220 (Legume lectin, beta domain)
7	T28F3.9	T28F3.9	n/a	chrIV 17,310,065	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
8	spp-19	K04A8.9	n/a	chrV 6,559,648	C. elegans SPP-19 protein; contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)
9	H11E01.2	H11E01.2	n/a	chrX 1,623,360	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
10	Y38H6C.4	Y38H6C.4	n/a	chrV 20,500,386	contains similarity to Mus musculus Similar to hypothetical protein FLJ21522 (Epidermal growth factorsreceptor pathway substrate 8 related protein 3).; TR:Q91WL0
11	lips-10	F14E5.5	n/a	chrII 8,440,581	C. elegans LIPS-10 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
12	H10E21.1	H10E21.1	n/a	chrIII 16,729
13	F29B9.11	F29B9.11	n/a	chrIV 4,659,939
14	clec-206	F59A7.1	n/a	chrV 2,002,373	C. elegans CLEC-206 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
15	dis-3	C04G2.6	n/a	chrIV 10,101,854	C. elegans DIS-3 protein; contains similarity to Pfam domains PF00773 (RNB domain) , PF08206 (Ribonuclease B OB domain) contains similarity to Interpro domains IPR013223 (Ribonuclease B, OB region N-terminal), IPR001356 (Homeobox), IPR006596 (Nucleotide binding protein, PINc), IPR006058 (2Fe-2S ferredoxin, iron-sulphur binding site), IPR001900 (Ribonuclease II and R)
16	F28B1.3	F28B1.3	n/a	chrV 17,053,645	contains similarity to Interpro domain IPR009021 ()
17	R09D1.7	R09D1.7	n/a	chrII 9,455,937	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR001574 (Ribosome-inactivating protein)
18	Y39A1A.6	Y39A1A.6	n/a	chrIII 10,616,526	contains similarity to Interpro domains IPR005727 (Ribosomal protein L22, bacterial-type), IPR001063 (Ribosomal protein L22/L17)
19	EGAP9.3	EGAP9.3	n/a	chrV 6,579,135	contains similarity to Pfam domain PF01531 Glycosyl transferase family 11 contains similarity to Interpro domain IPR002516 (Glycosyl transferase, family 11)
20	sre-12	T07H8.7	n/a	chrV 6,978,417	C. elegans SRE-12 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR001680 (WD40 repeat)
21	F58E2.4	F58E2.4	n/a	chrIV 3,465,102	contains similarity to Pfam domains PF01827 (FTH domain) (2), PF00646 (F-box domain) contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
22	nhr-215	T07C5.4	n/a	chrX 12,699,419	C. elegans NHR-215 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
23	T01C3.2	T01C3.2	n/a	chrV 14,991,380	T01C3.2 encodes a divergent ortholog of Drosophila melanogaster E(Y)2 and budding yeast Sus1p; by orthology, T01C3.2 is predicted to enable both transcriptional activation and silencing in chromatin; however, T01C3.2 has no obvious function in mass RNAi assays.
24	C04G6.2	C04G6.2	n/a	chrII 5,093,709	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
25	srx-116	W05B10.5	n/a	chrV 12,671,795	C. elegans SRX-116 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
26	C01G6.9	C01G6.9	n/a	chrII 9,294,851	contains similarity to Plasmodium falciparum SET-domain protein, putative.; TR:Q8IC77
27	T27F6.6	T27F6.6	n/a	chrI 12,492,740	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domain IPR005135 (Endonuclease/exonuclease/phosphatase)
28	T16A9.4	T16A9.4	n/a	chrV 14,218,017	T16A9.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while T16A9.4 has no clear orthologs in other organisms, it falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).
29	figl-1	F32D1.1	n/a	chrV 4,343,730	F32D1.1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant F32D1.1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; F32D1.1 is required for persistence of the germline in RNAi assays.
30	lig-4	C07H6.1	n/a	chrIII 7,523,062	lig-4 encodes an ortholog of DNA ligase IV in budding yeast (DNL4) and human (LIG4; OMIM:601837, mutated in LIG4 syndrome); LIG-4 is required for resistance to ionizing radiation (IR) in somatic tissues (such as motor neurons, vulva, or uterus) and in endoreduplicating intestinal cells, but not in the germline (e.g., in dog-1-induced lesions); LIG-4 is required for non-homologous end-joining of double-stranded breaks (DSB) in somatic genomic DNA; although LIG-4 is not strongly required in the germline, it is active on DSB of DNA injected into syncytial gonads, and its absence enhances the hypersensitivity of rad-51(RNAi) germlines to ionizing radiation; in meiotic cells deprived of homologous DNA repair by a rad-51(Ig08701) mutation, both LIG-4 and BRC-2 can promote chromosomal aggregation (presumably by repairing meiotic double-stranded breaks in DNA), but they do so independently; mutant lig-4 late-stage embryos or dauer larvae are hypersensitive to radiation-induced DNA damage in somatic cells; after irradiation, lig-4 mutants tend to display various postembryonic phenotypes (such as slow growth, uncoordinated locomotion, impaired egg-laying, or vulval defects) that are thought to reflect missegregation of fragmented chromosomes; LIG-4 is N-terminally acetylated on a serine residue.
31	C23H5.7	C23H5.7	n/a	chrIV 2,107,829	contains similarity to Pfam domains PF00027 (Cyclic nucleotide-binding domain) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000595 (Cyclic nucleotide-binding), IPR014710 (RmlC-like jelly roll fold)
32	F36F12.7	F36F12.7	n/a	chrV 2,099,700
33	str-209	F26G5.5	n/a	chrV 4,949,965	C. elegans STR-209 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	M163.2	M163.2	n/a	chrX 14,497,680	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
35	F18F11.1	F18F11.1	n/a	chrIV 335,994	contains similarity to Interpro domain IPR014467 (Peroxisomal membrane protein 4)
36	F58G11.2	F58G11.2	n/a	chrV 13,667,324	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR002952 (Eggshell protein), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
37	cyp-33E3	F42A9.4	n/a	chrIV 8,615,428	C. elegans CYP-33E3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I)
38	ZC190.7	ZC190.7	n/a	chrV 8,686,461
39	T07F10.6	T07F10.6	n/a	chrV 12,865,830	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
40	F53F1.3	F53F1.3	n/a	chrV 13,409,019	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
41	T25F10.1	T25F10.1	n/a	chrV 6,768,591
42	C18G1.6	C18G1.6	n/a	chrV 4,752,187	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
43	W09G12.9	W09G12.9	n/a	chrIV 1,217,448
44	C03A7.2	C03A7.2	n/a	chrV 5,182,798
45	F34H10.2	F34H10.2	n/a	chrX 9,630,584	contains similarity to Anabaena sp Hypothetical protein Alr0331.; TR:Q8YZX4
46	fbxa-84	T09F5.11	n/a	chrV 15,183,260	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
47	osm-9	B0212.5	n/a	chrIV 3,554,256	The osm-9 gene encodes a capsaicin receptor homolog involved in sensory responses to a subset of chemical stimuli and to ASH neuron-mediated osmotic and mechanical stimuli; OSM-9 is also involved in adaptation to volatile odorants and salts.
48	T07D3.6	T07D3.6	n/a	chrII 881,565	contains similarity to Pfam domain PF06828 Fukutin-related contains similarity to Interpro domain IPR009644 (Fukutin-related)
49	try-10	F15B9.5	n/a	chrV 13,011,526	C. elegans TRY-10 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine)
50	F22G12.3	F22G12.3	n/a	chrI 13,153,129	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.