UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C40A11.6	C40A11.6	1e-119	chrII 2,144,971	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
2	F54D8.6	F54D8.6	n/a	chrIII 5,104,430	contains similarity to Interpro domain IPR000694 (Proline-rich region)
3	mkk-4	F42G10.2	n/a	chrX 10,028,926	mkk-4 encodes a MAP (mitogen-activated protein) kinase kinase that is a member of the MKK4 family of MAPKK's; MKK-4 activity is required in presynaptic neurons, in a dose-dependent manner, for normal presynaptic development and morphology; in regulating presynaptic organization, MKK-4 acts upstream of PMK-3/MAPK and downstream of DLK-1/MAPKKK, whose levels are negatively regulated by the RPM-1 ubiquitin ligase; a functional MKK-4::GFP fusion protein is expressed in the cytoplasm of many neurons as well as in other cell types, including the pharyngeal muscles.
4	T10B5.3	T10B5.3	n/a	chrV 1,866,374	contains similarity to Pfam domain PF08162 NUC189 domain contains similarity to Interpro domain IPR012979 (Protein of unknown function NUC189, C-terminal)
5	T10D4.11	T10D4.11	n/a	chrII 3,149,102	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
6	R151.1	R151.1	n/a	chrIII 7,218,656
7	F38A1.6	F38A1.6	n/a	chrIV 1,252,165
8	C30G12.1	C30G12.1	n/a	chrII 7,300,470	contains similarity to Pfam domain PF06394 Pepsin inhibitor-3-like repeated domain contains similarity to Interpro domain IPR010480 (Proteinase inhibitor I33, aspin)
9	F47B3.3	F47B3.3	n/a	chrI 3,964,844	contains similarity to Pfam domain PF01284 Membrane-associating domain contains similarity to Interpro domain IPR008253 (Marvel)
10	C30E1.7	C30E1.7	n/a	chrX 16,915,205
11	ZK418.7	ZK418.7	n/a	chrIII 7,079,862	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003842 (Vacuolating cytotoxin), IPR000276 (GPCR, rhodopsin-like)
12	C33F10.11	C33F10.11	n/a	chrII 4,834,476
13	fbxa-11	T12B5.4	n/a	chrIII 951,455	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
14	F25H9.1	F25H9.1	n/a	chrV 13,454,521	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
15	C05B5.5	C05B5.5	n/a	chrIII 10,002,152	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
16	T19D12.9	T19D12.9	n/a	chrII 6,653,312	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
17	Y18D10A.9	Y18D10A.9	n/a	chrI 12,855,664	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
18	F52H2.6	F52H2.6	n/a	chrX 2,561,931	F52H2.6 is orthologous to the human gene 3BETA-HYDROXYSTEROL DELTA 24 REDUCTASE (DHCR24; OMIM:606418), which when mutated leads to disease.
19	ZC190.2	ZC190.2	n/a	chrV 8,682,033	contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
20	T10B5.2	T10B5.2	n/a	chrV 1,849,449
21	hint-1	F21C3.3	n/a	chrI 7,280,150	C. elegans HINT-1 protein; contains similarity to Pfam domain PF01230 HIT domain contains similarity to Interpro domains IPR001310 (Histidine triad (HIT) protein), IPR011151 (Histidine triad motif), IPR011146 (Histidine triad-like motif)
22	F58B6.1	F58B6.1	n/a	chrIII 1,114,111	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domain IPR002921 (Lipase, class 3)
23	C30F12.1	C30F12.1	n/a	chrI 6,957,790	contains similarity to Pfam domain PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) contains similarity to Interpro domain IPR000571 (Zinc finger, CCCH-type)
24	F16G10.9	F16G10.9	n/a	chrII 2,385,448	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
25	F40F9.5	F40F9.5	n/a	chrV 9,721,836	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
26	C02C2.5	C02C2.5	n/a	chrIII 7,877,970	contains similarity to Pfam domain PF00881 Nitroreductase family contains similarity to Interpro domain IPR000415 (Nitroreductase)
27	cah-2	D1022.8	n/a	chrII 7,481,896	cah-2 encodes a predicted carbonic anhydrase.
28	pgp-2	C34G6.4	n/a	chrI 5,891,285	pgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family and that is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); during development, pgp-2 activity is required, in parallel with that of the AP-3 adaptor complex, for the proper formation of gut granules, lysosome-related fat storage organelles found in the C. elegans intestine; pgp-2 is expressed in the intestine, from the E2 stage of embryonic development through adulthood; PGP-2 localizes to the gut granule membrane.
29	tba-9	F40F4.5	n/a	chrX 3,254,559	tba-9 encodes one of nine C. elegans alpha tubulins; by homology, TBA-9 is predicted to be a component of microtubules; as loss of tba-9 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, TBA-9 likely functions redundantly with other alpha tubulins as a basic component of cellular architecture that may play additional roles in processes such as cell division, cell movement, and intracellular transport.
30	F59F5.3	F59F5.3	n/a	chrX 10,539,693	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
31	fbxa-118	M162.8	n/a	chrV 19,772,016	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
32	C39E9.7	C39E9.7	n/a	chrIV 13,074,688	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
33	T13C5.4	T13C5.4	n/a	chrX 6,192,236	T13C5.4 encodes a paired-like homeodomain protein of the Q50 class, which has no obvious function in mass RNAi assays.
34	ZC132.9	ZC132.9	n/a	chrV 4,318,616
35	ugt-41	F10D2.11	n/a	chrV 7,162,312	C. elegans UGT-41 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
36	F54C9.11	F54C9.11	n/a	chrII 8,584,206	contains similarity to Interpro domain IPR008126 (Outer membrane adhesion, Yersinia)
37	D2085.7	D2085.7	n/a	chrII 8,647,166
38	srx-58	C29F3.6	n/a	chrV 15,353,194	C. elegans SRX-58 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
39	T09E11.3	T09E11.3	n/a	chrI 12,369,888	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
40	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	ZK1248.7	ZK1248.7	n/a	chrII 5,813,080	contains similarity to Pfam domain PF02171 Piwi domain contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
42	wrt-9	B0344.2	n/a	chrX 1,583,762	wrt-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of proline-rich, low-complexity sequence; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-9 has no obvious function in RNAi assays.
43	T19B10.9	T19B10.9	n/a	chrV 11,249,483	contains similarity to Interpro domain IPR000694 (Proline-rich region)
44	twk-28	C52B9.6	n/a	chrX 4,276,975	C. elegans TWK-28 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
45	F55A4.1	F55A4.1	n/a	chrX 1,036,270	contains similarity to Pfam domain PF00957 Synaptobrevin contains similarity to Interpro domains IPR010908 (Longin), IPR011012 (Longin-like), IPR001388 (Synaptobrevin)
46	Y37A1A.3	Y37A1A.3	n/a	chrIV 13,900,330	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
47	K04G2.9	K04G2.9	n/a	chrI 8,056,298	contains similarity to Pfam domain PF01284 Membrane-associating domain contains similarity to Interpro domain IPR008253 (Marvel)
48	F28C6.8	F28C6.8	n/a	chrII 8,607,222	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
49	F59A3.1	F59A3.1	n/a	chrI 5,525,077	F59A3.1 encodes one of two C. elegans carboxypeptidase D homologs; loss of F59A3.1 activity via large-scale RNAi screens in a sensitized, rrf-3 mutant background results in larval lethality, abnormal locomotion, and abnormal morphogenesis of the vulval epithelium resulting in rupture; high-throughput expression studies report F59A3.1 expression in the pharynx only.
50	T12G3.4	T12G3.4	n/a	chrIV 12,049,069	contains similarity to Pfam domain PF03088 Strictosidine synthase contains similarity to Interpro domains IPR004141 (Strictosidine synthase), IPR011042 (Six-bladed beta-propeller, TolB-like)