UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C39D10.2	C39D10.2	3.9999999999999997e-122	chrX 7,889,123
2	nas-28	F42A10.8	n/a	chrIII 6,182,093	C. elegans NAS-28 protein; contains similarity to Pfam domain PF01400 Astacin (Peptidase family M12A) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
3	R11D1.3	R11D1.3	n/a	chrV 12,711,700	contains similarity to Proteus mirabilis Hypothetical protein (Fragment).; TR:O86985
4	F19F10.1	F19F10.1	n/a	chrV 7,563,460	contains similarity to Pfam domain PF00178 Ets-domain contains similarity to Interpro domains IPR000418 (Ets), IPR011991 (Winged helix repressor DNA-binding)
5	F43G9.5	F43G9.5	n/a	chrI 8,615,863	F43G9.5 encodes a NUDIX hydrolase that that inhibits DHC-1 in vivo, and is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; F43G9.5(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that F43G9.5 negatively regulates dynein; while loss of F43G9.5 function has no obvious effect on lifespan, dauer formation, or fat storage, F43G9.5 is required for embryonic development, fertility, and general health in mass RNAi assays.
6	zig-5	Y48A6A.1	n/a	chrIII 10,952,247	zig-5 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-5::gfp reporter fusion is expressed in a number of neurons, including PVT, VD1-13, RID, AFD, ASK, RIV, RIB, PVQ, DVA, and RIS; zig-5::gfp is detected in the PVT neuron beginning at the three-fold stage of embryogenesis and continuing throughout larval development; loss of zig-5 activity in large-scale RNAi screens has been reported to result in low levels of embryonic lethality.
7	fipr-23	C37A5.4	n/a	chrI 14,153,722	C. elegans FIPR-23 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
8	K12B6.4	K12B6.4	n/a	chrV 6,280,741
9	nas-17	K03B8.2	n/a	chrV 11,399,699	nas-17 encodes an astacin-like metalloprotease.
10	B0228.8	B0228.8	n/a	chrII 7,760,555
11	K04H8.3	K04H8.3	n/a	chrI 14,256,314	contains similarity to Bacteroides thetaiotaomicron Putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismatesmutase.; TR:Q8A0T7
12	F07G11.7	F07G11.7	n/a	chrV 7,303,485	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
13	F52E1.8	F52E1.8	n/a	chrV 8,393,368	contains similarity to Pfam domains PF00300 (Phosphoglycerate mutase family) , PF00328 (Histidine acid phosphatase) contains similarity to Interpro domains IPR000560 (Histidine acid phosphatase), IPR013078 (Phosphoglycerate mutase)
14	C47D2.1	C47D2.1	n/a	chrX 8,215,243
15	fipr-22	C37A5.2	n/a	chrI 14,155,893	C. elegans FIPR-22 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
16	tsp-1	C02F5.8	n/a	chrIII 8,238,638	C. elegans TSP-1 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin), IPR013305 (ABC transporter, ABCB2), IPR003091 (Voltage-dependent potassium channel)
17	F10F2.4	F10F2.4	n/a	chrIII 4,624,572	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
18	F32B6.10	F32B6.10	n/a	chrIV 9,888,531	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
19	T21C12.3	T21C12.3	n/a	chrIII 10,538,504	contains similarity to Leptospira interrogans Hypothetical protein.; TR:Q8EZD2
20	clec-108	Y26D4A.6	n/a	chrI 13,081,794	C. elegans CLEC-108 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
21	ZK1248.1	ZK1248.1	n/a	chrII 5,843,377	ZK1248.1 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; ZK1248.1 has no clear orthologs in other organisms.
22	W07G1.7	W07G1.7	n/a	chrII 13,965,516
23	T21C9.11	T21C9.11	n/a	chrV 10,594,469	contains similarity to Homo sapiens Popeye domain containing protein 3; ENSEMBL:ENSP00000254765
24	C54C6.5	C54C6.5	n/a	chrIII 3,549,652	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_4440.; TR:Q98QC2
25	ZC328.5	ZC328.5	n/a	chrI 6,406,411
26	W03G1.2	W03G1.2	n/a	chrIV 525,588	contains similarity to Interpro domain IPR005819 (Histone H5)
27	F19H6.6	F19H6.6	n/a	chrX 12,362,704	contains similarity to Saccharomyces cerevisiae Cytoplasmic protein of unknown function, potential Cdc28p substrate; SGD:YAL031C
28	T10D4.7	T10D4.7	n/a	chrII 3,118,051	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
29	ZK353.4	ZK353.4	n/a	chrIII 8,388,992	contains similarity to Schizosaccharomyces pombe Uncharacterized serine/threonine-rich protein PB15E9.01c precursor.; SW:Q8TFG9
30	sri-37	D2062.2	n/a	chrII 2,630,401	C. elegans SRI-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	K06A4.2	K06A4.2	n/a	chrV 9,487,363	contains similarity to Pfam domains PF00293 (NUDIX domain) , PF05026 (Dcp2, box A domain) contains similarity to Interpro domains IPR015797 (NUDIX), IPR007722 (Dcp2, box A), IPR000086 (NUDIX hydrolase, core)
32	F53E10.4	F53E10.4	n/a	chrV 2,593,813
33	F20A1.2	F20A1.2	n/a	chrV 7,047,678	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
34	T05A6.4	T05A6.4	n/a	chrII 7,821,360	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
35	ida-1	B0244.2	n/a	chrIII 5,760,627	ida-1 encodes a protein tyrosine phosphatase-like receptor, orthologous to the mammalian type I diabetes autoantigens IA-2 and phogrin that are expressed in dense core vesicles of neuroendocrine tissue and involved in regulated protein secretion; in C. elegans, IDA-1 appears to be required for regulating presynaptic neurotransmission and in particular, for the neuropeptidergic control of egg-laying; ida-1 interacts genetically with unc-31 and unc-64, which encode proteins required for dense core vesicle fusion and exocytosis; ida-1 expression is detected in a subset of neurons in the anterior nerve ring, the ventral nerve cord, the tail, and the vulva, including the VC vulval motoneurons and the HSN egg-laying neurons; ida-1 is also detected in the vulval uv1 cells, non-neuronal cells that contain neurosecretory-like vesicles.
36	F41D3.8	F41D3.8	n/a	chrI 12,267,803	contains similarity to Pfam domain PF01697 (Domain of unknown function)
37	cwp-2	C37H5.11	n/a	chrV 4,842,261	cwp-2 encodes a nematode-specific protein that is coexpressed with lov-1 and pkd-2.
38	clec-158	R13F6.8	n/a	chrIII 6,859,120	C. elegans CLEC-158 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
39	T26G10.5	T26G10.5	n/a	chrIII 9,426,015	contains similarity to Streptococcus pyogenes Hypothetical protein SPy0952.; TR:Q9A032
40	W02B3.7	W02B3.7	n/a	chrIII 691,490	contains similarity to Interpro domain IPR009644 (Fukutin-related)
41	aqp-3	Y69E1A.7	n/a	chrIV 10,962,555	aqp-3 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases water or glycerol permeability five- to seven-fold; loss of AQP-3 activity via mutation or RNAi results in no obvious defects; however, AQP-3, in conjunction with AQP-2, AQP-4, and AQP-8, is weakly required for recovery from hypotonic stress; AQP-3 is expressed in the intestine, excretory cell, seminal vesicle, and vas deferens.
42	flp-21	C26F1.10	n/a	chrV 7,793,674	flp-21 encodes a single FMRFamide-related neuropeptide (FaRP) that serves as a ligand for NPR-1, a G protein-coupled receptor that regulates social versus solitary feeding behavior in several Caenorhabditis species; genetic analysis suggests that FLP-21 acts through NPR-1 to inhibit social feeding behavior; FLP-21 is expressed in the ADL, ASE and ASH sensory neurons, the URA motor neurons, the MC, M2 and M4 pharyngeal neurons, and the intestine; flp-21 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome that activates both the social (215F) and the solitary (215V) forms of NPR-1 in both Xenopus oocytes and pharyngeal assays.
43	ubc-22	C06E2.7	n/a	chrX 8,868,414	ubc-22 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae UBC8 and human UBC1/HIP2 (Huntingtin interacting protein 2, OMIM:602846) which are involved in regulating fructose-1,6-bisphosphatase and huntingtin catabolism, respectively; by homology, UBC-22 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-22 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-22 in C. elegans development and/or behavior is not yet known.
44	F47C12.8	F47C12.8	n/a	chrIV 3,997,448	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
45	F09E10.1	F09E10.1	n/a	chrX 1,503,048
46	clec-124	C17F4.1	n/a	chrII 3,250,580	C. elegans CLEC-124 protein; contains similarity to Interpro domain IPR016187 (C-type lectin fold)
47	clec-217	F26D11.9	n/a	chrV 7,958,038	C. elegans CLEC-217 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
48	E02H9.9	E02H9.9	n/a	chrIII 2,467,742
49	K12H6.9	K12H6.9	n/a	chrII 2,824,679
50	sul-2	D1014.1	n/a	chrV 8,158,775	sul-2 is orthologous to the human gene ARYLSULFATASE A (ARSA; OMIM:250100), which when mutated leads to metachromatic leukodystrophy.