UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C38C3.7	C38C3.7	0	chrV 1,502,860	contains similarity to Pfam domains PF01827 (FTH domain) (2), PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
2	abt-3	F55G11.9	n/a	chrIV 12,953,691	abt-3 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-3 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-3 activity via RNAi results in no obvious defects, the precise role of abt-3 in C. elegans development and/or behavior is not yet known.
3	F29A7.3	F29A7.3	n/a	chrII 2,753,579	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
4	F45C12.9	F45C12.9	n/a	chrII 1,709,067	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
5	F54C4.4	F54C4.4	n/a	chrIII 87,055
6	Y48E1C.3	Y48E1C.3	n/a	chrII 13,439,410	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
7	C04E7.1	C04E7.1	n/a	chrX 359,435
8	Y17G7B.19	Y17G7B.19	n/a	chrII 12,110,327	contains similarity to Pfam domain PF01666 (DX module)
9	php-3	Y75B8A.1	n/a	chrIII 12,075,804	C. elegans PHP-3 protein; contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000047 (Helix-turn-helix motif, lambda-like repressor), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
10	pqn-84	Y41C4A.5	n/a	chrIII 11,701,451	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
11	R05G6.1	R05G6.1	n/a	chrIV 7,539,920
12	gcy-18	ZK896.8	n/a	chrIV 12,863,005	gcy-18 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-18 functions redundantly with gcy-8 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, microarray experiments indicate that gcy-18 expression is induced in daf-16(RNAi); daf-2(RNAi) double mutants and repressed in daf-2(RNAi) mutants, suggesting that GCY-18 activity may contribute to a shortened lifespan; consistent with this, loss of gcy-18 activity via RNAi does result in lifespan extension; GCY-18 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
13	C33E10.5	C33E10.5	n/a	chrX 17,276,148	contains similarity to Interpro domain IPR000173 (Glyceraldehyde 3-phosphate dehydrogenase)
14	str-143	C09H5.4	n/a	chrV 8,068,920	C. elegans STR-143 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	C06C3.9	C06C3.9	n/a	chrII 9,377,271
16	T20B6.1	T20B6.1	n/a	chrIII 2,898,031	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
17	T04G9.1	T04G9.1	n/a	chrX 792,247	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000694 (Proline-rich region)
18	rab-14	K09A9.2	n/a	chrX 15,605,871	rab-14 encodes a member of the Rab GTPase family.
19	W05B5.1	W05B5.1	n/a	chrI 13,043,893	contains similarity to Saccharomyces cerevisiae Homolog of human WASP, proline-rich protein; SGD:YOR181W
20	T11F1.3	T11F1.3	n/a	chrII 2,955,703
21	R02F11.2	R02F11.2	n/a	chrV 4,795,145
22	Y51A2D.18	Y51A2D.18	n/a	chrV 18,484,174	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
23	F47F6.4	F47F6.4	n/a	chrII 1,262,570
24	E01G4.1	E01G4.1	n/a	chrII 13,445,298	contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
25	F57C12.2	F57C12.2	n/a	chrX 548,426	contains similarity to Pfam domain PF04670 Gtr1/RagA G protein conserved region contains similarity to Interpro domains IPR009053 (Prefoldin), IPR006762 (Gtr1/RagA G protein)
26	4R79.2	4R79.2	n/a	chrIV 17,481,819	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR006688 (ADP-ribosylation factor), IPR002041 (Ran GTPase), IPR013753 (Ras), IPR006687 (GTP-binding protein SAR1), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR005225 (Small GTP-binding protein), IPR003579 (Ras small GTPase, Rab type)
27	Y48A6B.1	Y48A6B.1	n/a	chrIII 10,993,565	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
28	fbxa-129	F59A1.8	n/a	chrV 17,656,084	C. elegans FBXA-129 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
29	fbxb-1	T26H2.1	n/a	chrV 19,240,953	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
30	F26F2.4	F26F2.4	n/a	chrV 20,565,244	contains similarity to Homo sapiens Laminin alpha-4 chain precursor; ENSEMBL:ENSP00000230538
31	grl-2	T16G1.8	n/a	chrV 12,945,836	grl-2 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-2 is expressed in neurons, amphid socket cells, and other cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
32	R13A1.1	R13A1.1	n/a	chrIV 7,220,097
33	D2005.6	D2005.6	n/a	chrI 7,790,102	contains similarity to Homo sapiens Fusion protein SYT-SSX1; ENSEMBL:ENSP00000269138
34	Y53C10A.5	Y53C10A.5	n/a	chrI 12,000,702	contains similarity to Interpro domain IPR000608 (Ubiquitin-conjugating enzyme, E2)
35	R107.2	R107.2	n/a	chrIII 9,044,850	contains similarity to Pfam domain PF01256 Carbohydrate kinase contains similarity to Interpro domain IPR000631 (Carbohydrate kinase)
36	W03F8.2	W03F8.2	n/a	chrIV 5,191,305	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif)
37	srz-103	F14F8.4	n/a	chrV 16,678,452	C. elegans SRZ-103 protein; contains similarity to Interpro domain IPR001046 (Natural resistance-associated macrophage protein)
38	F07C3.2	F07C3.2	n/a	chrV 9,226,731
39	F16H6.6	F16H6.6	n/a	chrV 18,205,786	contains similarity to Anthyllis vulneraria subsp lapponica Maturase-like protein.; TR:Q8HUG8
40	srg-46	F32H5.5	n/a	chrV 13,364,203	C. elegans SRG-46 protein ;
41	C38H2.1	C38H2.1	n/a	chrIII 10,369,054	contains similarity to Pfam domains PF00566 (TBC domain) , PF02759 (RUN domain) contains similarity to Interpro domains IPR000195 (RabGAP/TBC), IPR004012 (RUN)
42	ZK1290.10	ZK1290.10	n/a	chrII 7,552,859	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003582 (Metridin-like ShK toxin)
43	Y81G3A.4	Y81G3A.4	n/a	chrII 13,092,774	contains similarity to Guillardia theta 60S acidic ribosomal protein P0.; TR:Q98S65
44	T21G5.2	T21G5.2	n/a	chrI 6,870,894
45	scl-23	B0545.3	n/a	chrIV 88,065	C. elegans SCL-23 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related), IPR014044 (SCP-like extracellular)
46	F21C3.6	F21C3.6	n/a	chrI 7,284,859	contains similarity to Homo sapiens Isoform 1 of Caldesmon; ENSEMBL:ENSP00000354826
47	W04E12.5	W04E12.5	n/a	chrV 19,742,714	contains similarity to Interpro domain IPR000750 (Proenkephalin B)
48	W02B8.3	W02B8.3	n/a	chrII 13,917,920	contains similarity to Pfam domain PF04870 Protein of unknown function, DUF644 contains similarity to Interpro domain IPR006954 (Protein of unknown function DUF644)
49	R07C3.10	R07C3.10	n/a	chrII 910,744
50	tkr-1	C38C10.1	n/a	chrIII 9,386,535	tkr-1 encodes a G protein-coupled receptor that is the C. elegans tachykinin-like neuropeptide receptor homolog; by homology, TKR-1 is predicted to function in modulation of excitatory neurotransmission; as loss of tkr-1 activity via RNAi results in moderate reduction of fat content, TKR-1 may play a specific role in regulating lipid metabolism; a tkr-1 reporter gene fusion is reportedly expressed in the socket cells of the deirid and post-deirid sensilla from the L2 larval stage through adulthood.