UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C36E8.1	C36E8.1	0	chrIII 4,001,753	contains similarity to Pfam domain PF05327 RNA polymerase I specific transcription initiation factor RRN3 contains similarity to Interpro domain IPR007991 (RNA polymerase I specific transcription initiation factor RRN3)
2	R17.2	R17.2	n/a	chrIII 10,842,361	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domain IPR005135 (Endonuclease/exonuclease/phosphatase)
3	lip-1	C05B10.1	n/a	chrIV 6,843,879	lip-1 encodes a mitogen-activated protein (MAP) kinase phosphatase homologous to the vertebrate dual specificity phosphatase MKP-3; during development, LIP-1 negatively regulates MAP kinase activity to control the extent of germline proliferation and oocyte meiotic cell cycle progression; lip-1 activity is also required redundantly with dep-1 to negatively regulate MAPK signaling during vulval induction; in addition, lip-1 is required for normal embryonic development; lip-1 expression begins during embryogenesis and continues through adulthood; expression is seen in most somatic cells and in germ cells of the pachytene region, transition zone and proximal-most region of the mitotic zone; in the pachytene region, LIP-1 is associated with the plasma membrane; in early L3 larvae, LIP-1 expression increases in secondary vulval precursor cells in a lin-12/Notch-dependent manner, suggesting that lip-1 may be a direct downstream target of lin-12-mediated signaling; interaction with the Notch pathway is further demonstrated by chromatin immunoprecipitation experiments showing that, in the germline, the lip-1 promoter region coprecipitates with LAG-3; germline lip-1 mRNA accumulation is negatively regulated by the FBF proteins (FBF-1 and FBF-2) that bind to the lip-1 3'UTR.
4	F56A11.5	F56A11.5	n/a	chrIV 569,608	contains similarity to Pfam domains PF03473 (MOSC domain) , PF03476 (MOSC N-terminal beta barrel domain) contains similarity to Interpro domains IPR005303 (MOSC, N-terminal beta barrel), IPR005302 (Molybdenum cofactor sulphurase, C-terminal), IPR001484 (Pyrokinin, conserved site), IPR011037 (Pyruvate kinase, beta-barrel-like)
5	D1081.8	D1081.8	n/a	chrI 8,493,557	contains similarity to Pfam domain PF00249 Myb-like DNA-binding domain contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR012287 (Homeodomain-related), IPR014778 (Myb, DNA-binding), IPR009057 (Homeodomain-like), IPR015495 (Myb transcription factor)
6	C26E6.6	C26E6.6	n/a	chrIII 4,936,354	contains similarity to Pfam domain PF00297 Ribosomal protein L3 contains similarity to Interpro domains IPR009000 (Translation elongation and initiation factors/Ribosomal, beta-barrel), IPR000597 (Ribosomal protein L3)
7	C34B2.5	C34B2.5	n/a	chrI 10,675,986	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013026 (Tetratricopeptide region)
8	F19F10.9	F19F10.9	n/a	chrV 7,573,793	The F19F10.9 gene encodes a homolog of the human SART1 gene, which encodes a protein recognised by IgE that may be involved in atopic disease.
9	vps-54	T21C9.2	n/a	chrV 10,571,379	The vps-54 gene encodes an ortholog of VPS54 in S. cerevisiae, a protein involved in vacuolar trafficking.
10	F54C9.9	F54C9.9	n/a	chrII 8,579,712	contains similarity to Pfam domain PF05178 Krr1 family contains similarity to Interpro domain IPR007851 (Kri1)
11	K01C8.6	K01C8.6	n/a	chrII 8,278,000	contains similarity to Drosophila pseudoobscura 39S ribosomal protein L10, mitochondrial precursor (L10mt) (MRP-L10).; SW:Q29NV5
12	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
13	ZK593.1	ZK593.1	n/a	chrIV 10,911,466	contains similarity to Pfam domains PF02887 (Pyruvate kinase, alpha/beta domain) , PF00224 (Pyruvate kinase, barrel domain) contains similarity to Interpro domains IPR015806 (Pyruvate kinase, beta-barrel), IPR015794 (Pyruvate kinase, alpha/beta), IPR015795 (Pyruvate kinase, C-terminal-like), IPR015813 (Pyruvate/Phosphoenolpyruvate kinase, catalytic core), IPR001697 (Pyruvate kinase), IPR015793 (Pyruvate kinase, barrel)
14	Y106G6H.8	Y106G6H.8	n/a	chrI 10,452,513	contains similarity to Pfam domain PF04241 Protein of unknown function (DUF423) contains similarity to Interpro domain IPR006696 (Protein of unknown function DUF423)
15	C30H6.7	C30H6.7	n/a	chrIV 17,381,384	contains similarity to Pfam domains PF00198 (2-oxoacid dehydrogenases acyltransferase (catalytic domain)) , PF02817 (e3 binding domain) contains similarity to Interpro domains IPR004167 (E3 binding), IPR001078 (Catalytic domain of components of various dehydrogenase complexes)
16	C05D11.10	C05D11.10	n/a	chrIII 6,431,356	contains similarity to Interpro domain IPR016027 (Nucleic acid-binding, OB-fold-like)
17	F55H12.2	F55H12.2	n/a	chrI 8,868,112	contains similarity to Interpro domain IPR000242 (Tyrosine specific protein phosphatase)
18	F49C12.14	F49C12.14	n/a	chrIV 9,323,277	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
19	C24F3.4	C24F3.4	n/a	chrIV 10,217,118	contains similarity to Pfam domains PF00795 (Carbon-nitrogen hydrolase) , PF02540 (NAD synthase) contains similarity to Interpro domains IPR003010 (Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR003694 (NAD+ synthase), IPR014445 (Glutamine-dependent NAD(+) synthetase, GAT region)
20	K01A11.3	K01A11.3	n/a	chrIII 3,450,547	contains similarity to Pfam domain PF00443 (Ubiquitin carboxyl-terminal hydrolases family 2)
21	rpl-36	F37C12.4	n/a	chrIII 7,180,363	rpl-36 encodes a large ribosomal subunit L36 protein; by homology, RPL-36 is predicted to function in protein biosynthesis; in C. elegans, RPL-36 activity is required for embryonic and germline development and normal postembryonic growth rates.
22	smp-2	D1037.2	n/a	chrI 3,669,414	C. elegans SMP-2 protein; contains similarity to Pfam domain PF01403 Sema domain contains similarity to Interpro domains IPR001627 (Semaphorin/CD100 antigen), IPR003659 (Plexin/semaphorin/integrin), IPR016201 (Plexin-like fold), IPR015943 (WD40/YVTN repeat-like)
23	C47E12.3	C47E12.3	n/a	chrIV 10,000,452	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
24	F17A9.4	F17A9.4	n/a	chrV 6,109,818	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal), IPR002343 (Paraneoplastic encephalomyelitis antigen)
25	R11D1.9	R11D1.9	n/a	chrV 12,729,002	contains similarity to Pfam domain PF05046 Mitochondrial large subunit ribosomal protein (Img2) contains similarity to Interpro domain IPR007740 (Ribosomal protein L49/IMG2)
26	D2007.4	D2007.4	n/a	chrIII 8,145,419	contains similarity to Drosophila melanogaster Flybase gene name is mRpL18-PA;; FLYBASE:CG12373
27	glrx-5	Y49E10.2	n/a	chrIII 12,373,098	C. elegans GLRX-5 protein; contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR014025 (Glutaredoxin subgroup), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004480 (Glutaredoxin-related protein)
28	ugt-19	K08B4.3	n/a	chrIV 6,078,341	C. elegans UGT-19 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
29	rabn-5	F01F1.4	n/a	chrIII 5,865,475	C. elegans RABN-5 protein; contains similarity to Pfam domains PF09311 (Rab5 binding) , PF01363 (FYVE zinc finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002867 (Zinc finger, C6HC-type), IPR015390 (Rabaptin, GTPase-Rab5 binding), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
30	C50E3.6	C50E3.6	n/a	chrV 7,589,517
31	gly-19	F22D6.12	n/a	chrI 7,113,932	gly-19 encodes a protein similar to 2/I N-acetylglucosaminyltransferase; it is probably coexpressed with gly-18 in the anal sphincter muscle.
32	Y40B1B.8	Y40B1B.8	n/a	chrI 13,431,748	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domain IPR001993 (Mitochondrial substrate carrier)
33	B0281.3	B0281.3	n/a	chrII 2,307,697	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR003058 (Cloacin), IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
34	F59B2.2	F59B2.2	n/a	chrIII 8,995,643	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR013057 (Amino acid transporter, transmembrane)
35	F09E5.12	F09E5.12	n/a	chrII 5,368,494	contains similarity to Pfam domain PF05001 RNA polymerase Rpb1 C-terminal repeat
36	F55A3.2	F55A3.2	n/a	chrI 10,795,710	contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR015880 (Zinc finger, C2H2-like)
37	CD4.8	CD4.8	n/a	chrV 5,600,286	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
38	sec-10	C33H5.9	n/a	chrIV 7,780,928	C. elegans SEC-10 protein; contains similarity to Pfam domain PF07393 Exocyst complex component Sec10 contains similarity to Interpro domain IPR009976 (Exocyst complex component Sec10)
39	C49H3.8	C49H3.8	n/a	chrIV 7,901,218	contains similarity to Pfam domain PF00022 Actin contains similarity to Interpro domains IPR001478 (PDZ/DHR/GLGF), IPR004000 (Actin/actin-like), IPR013126 (Heat shock protein 70)
40	C50F2.3	C50F2.3	n/a	chrI 3,878,907	contains similarity to Pfam domain PF02184 HAT (Half-A-TPR) repeat contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013212 (Mad3/BUB1 homology region 1), IPR003107 (RNA-processing protein, HAT helix)
41	Y57G11C.4	Y57G11C.4	n/a	chrIV 14,766,103	contains similarity to Pfam domain PF05008 Vesicle transport v-SNARE protein contains similarity to Interpro domains IPR000727 (Target SNARE coiled-coil region), IPR007705 (Vesicle transport v-SNARE)
42	cif-1	K08F11.3	n/a	chrIV 4,708,690	C. elegans CIF-1 protein; contains similarity to Pfam domain PF01399 PCI domain contains similarity to Interpro domain IPR000717 (Proteasome component region PCI)
43	syn-3	F55A11.2	n/a	chrV 11,766,040	C. elegans SYN-3 protein; contains similarity to Pfam domains PF00804 (Syntaxin) , PF05739 (SNARE domain) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR006011 (Syntaxin, N-terminal), IPR000727 (Target SNARE coiled-coil region), IPR006012 (Syntaxin/epimorphin, conserved site)
44	C25F9.9	C25F9.9	n/a	chrV 19,417,227	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IE25
45	apm-3	F53H8.1	n/a	chrX 956,347	apm-3 encodes an adaptin, orthologous to the mu3 subunit of adaptor protein complex 3 (AP-3); APM-3 is also orthologous to human HPS, which when mutated leads to Hermansky-Pudlak syndrome (OMIM:203300); based on structural similarity, APM-3 is predicted to be involved in the formation of intracellular transport vesicles, and genetic analyses indicate that apm-3 activity is required for biogenesis of lysosome-related gut granules.
46	ifa-4	K05B2.3	n/a	chrX 4,914,125	IFA-4 encodes a nonessential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-4 binds IFB-1 in blot overlay assays; ifa-4 is expressed in larvae in the pharyngeal-intestinal valve, the rectum, some neurons of the tail, the excretory cell, and the intestine of dauer (but not nondauer) larvae; IFA-4 has no function in RNAi assays.
47	T19D12.9	T19D12.9	n/a	chrII 6,653,312	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
48	cyp-25A2	C36A4.2	n/a	chrIII 3,836,163	C. elegans CYP-25A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
49	eri-3	W09B6.3	n/a	chrII 1,125,668	C. elegans ERI-3 protein ;
50	ddb-1	M18.5	n/a	chrIV 12,117,957	M18.5 is orthologous to the human gene DAMAGE-SPECIFIC DNA BINDING PROTEIN 1 (127KD) (DDB1; OMIM:600045), which when mutated leads to disease.