UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C36C5.5	C36C5.5	4e-110	chrV 3,157,450	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	mab-9	T27A1.6	n/a	chrII 518,813	mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 affects movement to some extent though the basis for this defect is unknown; MAB-9 localizes to the nucleus of B and F and their descendents during development.
4	tps-2	F19H8.1	n/a	chrII 14,605,629	tps-2 encodes one of two trehalose-6-phosphate synthase proteins in C. elegans, and RNAi of both enzymes leads to a more than 90% reduction decrease in trehalose levels, but does not appear to affect viability or development; the tps-2 mRNA is expressed throughout development.
5	F59A6.3	F59A6.3	n/a	chrII 5,009,745	contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
6	F22B3.8	F22B3.8	n/a	chrIV 11,423,572	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
7	R102.7	R102.7	n/a	chrIV 10,703,834
8	T22G5.1	T22G5.1	n/a	chrV 13,877,372	contains similarity to Pfam domain PF03009 Glycerophosphoryl diester phosphodiesterase family contains similarity to Interpro domain IPR004129 (Glycerophosphoryl diester phosphodiesterase)
9	lec-4	C44F1.3	n/a	chrIII 3,772,356	lec-4 encodes a predicted galectin that exhibits sugar binding properties in vitro.
10	F37A8.2	F37A8.2	n/a	chrIII 3,930,465	contains similarity to Homo sapiens Protein transport protein Sec24B; ENSEMBL:ENSP00000265175
11	M70.2	M70.2	n/a	chrIV 2,243,378	contains similarity to Homo sapiens Serine/threonine-protein kinase PRP4 homolog; ENSEMBL:ENSP00000283003
12	R07C3.4	R07C3.4	n/a	chrII 934,987	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
13	W03F9.3	W03F9.3	n/a	chrV 132,775
14	tag-212	T14D7.3	n/a	chrII 8,859,305	C. elegans TAG-212 protein; contains similarity to Pfam domain PF00957 Synaptobrevin contains similarity to Interpro domain IPR001388 (Synaptobrevin)
15	F21H7.2	F21H7.2	n/a	chrV 16,228,334	contains similarity to Homo sapiens Neurofilament heavy polypeptide; ENSEMBL:ENSP00000311997
16	grl-22	W03A5.3	n/a	chrIII 5,413,566	grl-22 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
17	C36C5.14	C36C5.14	1e-35	chrV 3,165,115	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
18	F59C6.2	F59C6.2	n/a	chrI 10,523,017	contains similarity to Pfam domain PF01529 DHHC zinc finger domain contains similarity to Interpro domain IPR001594 (Zinc finger, DHHC-type)
19	R07E5.6	R07E5.6	n/a	chrIII 4,399,849	contains similarity to Interpro domains IPR005432 (Gamma-aminobutyric-acid A receptor, alpha 2 subunit), IPR009149 (BR22)
20	F28A10.1	F28A10.1	n/a	chrII 826,849	F28A10.1 encodes a putative small-molecule methyltransferase, belonging to a large nematode-specific expanded family; F28A10.1 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51; F28A10.1 is expressed in neurons, and F28A10.1 transcripts are enriched in spermatogenesis; although F's obvious homologs are all Caenorhabditis proteins, it has distant similarity to 31-O-demethyl-FK506 methyltransferase (FkbM) from Streptomyces, to other bacterial FkbM homologs, and to other metazoan homologs such as human LOC728464.
21	K07A12.5	K07A12.5	n/a	chrI 8,694,231	contains similarity to Plasmodium falciparum Glutamic acid-rich protein precursor.; SW:GARP_PLAFF
22	F58H1.6	F58H1.6	n/a	chrV 11,943,743	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site)
23	F36A4.2	F36A4.2	n/a	chrIV 4,271,510	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
24	R09E10.3	R09E10.3	n/a	chrIV 10,312,202	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
25	R04B5.11	R04B5.11	n/a	chrV 10,090,998	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000248104
26	C08F8.4	C08F8.4	n/a	chrIV 11,158,277	contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
27	Y45F10B.3	Y45F10B.3	n/a	chrIV 13,593,732	contains similarity to Saccharomyces cerevisiae N-terminal domain appears to be involved in cellular responsiveness to RAS.; SGD:YNL138W
28	F57G4.5	F57G4.5	n/a	chrV 17,642,359	contains similarity to Mus musculus Dentin sialophosphoprotein precursor (Dentin matrix protein-3) (DMP-s3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP);sDentin sialoprotein (DSP)].; SW:DSPP_MOUSE
29	C47E12.11	C47E12.11	n/a	chrIV 9,970,520	contains similarity to Mus musculus Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolylsisomerase G) (PPIase G) (Rotamase G) (Cyclophilin G).; SW:A2AR02
30	F35H10.2	F35H10.2	n/a	chrIV 8,329,510
31	col-33	F36A4.6	n/a	chrIV 4,264,264	col-33 encodes a predicted cuticular collagen; by homology, col-33 is predicted to play a role in cuticle biosynthesis and regulation of body size and morphogenesis; however, as loss of col-33 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of COL-33 in C. elegans development and/or behavior is not yet known.
32	F15E6.4	F15E6.4	n/a	chrIV 4,291,666
33	Y11D7A.1	Y11D7A.1	n/a	chrIV 9,229,724	contains similarity to Interpro domains IPR003702 (Acetyl-CoA hydrolase/transferase), IPR001220 (Legume lectin, beta domain)
34	ZK1225.5	ZK1225.5	n/a	chrI 13,217,724
35	B0207.9	B0207.9	n/a	chrI 5,957,923
36	F22F4.4	F22F4.4	n/a	chrX 6,000,544
37	C32D5.4	C32D5.4	n/a	chrII 6,322,171
38	ZC581.2	ZC581.2	n/a	chrI 6,656,611	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
39	D2096.10	D2096.10	n/a	chrIV 8,388,092
40	C10G11.1	C10G11.1	n/a	chrI 6,307,930
41	C07E3.3	C07E3.3	n/a	chrII 10,355,550	contains similarity to Ambrosia artemisiifolia Pollen allergen Amb a 1.2 precursor (Antigen E) (Antigen Amb a I).; SW:MP12_AMBAR
42	R11E3.1	R11E3.1	n/a	chrIV 4,790,837	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
43	gcy-12	F08B1.2	n/a	chrII 5,314,665	gcy-12 encodes a membrane guanylyl cyclase; a gcy-12::GFP reporter is expressed in the PHA neurons as well as in a number of head sensory neurons including AFD, AWC, and ASE; when expressed in COS-M6 cells, GCY-12 exhibits temperature-dependent guanylyl cyclase activity.
44	F46F5.6	F46F5.6	n/a	chrII 814,673	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
45	ZK930.5	ZK930.5	n/a	chrII 11,882,963	contains similarity to Methanobacterium thermoautotrophicum Phosphoserine phosphatase.; TR:O27663
46	C14A6.6	C14A6.6	n/a	chrV 18,166,242	contains similarity to Saccharomyces cerevisiae involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi; SGD:YDL058W
47	F25E2.2	F25E2.2	n/a	chrX 808,888	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
48	C49A1.2	C49A1.2	n/a	chrI 14,210,845	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
49	F47D12.3	F47D12.3	n/a	chrIII 6,298,853	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
50	F54C9.3	F54C9.3	n/a	chrII 8,566,635	contains similarity to Homo sapiens BA424I5.1; TR:Q9H4Q7