UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C33D9.5	C33D9.5	0	chrIV 8,779,611	C33D9.5 encodes a predicted coiled-coil protein; as loss of C33D9.5 activity via large-scale RNAi results in no obvious abnormalities, the precise role of C33D9.5 in C. elegans development and/or behavior is not yet known.
2	ceh-43	C28A5.4	n/a	chrIII 4,448,260	A homeobox protein of the Distal-less (Dll) class that is required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability; it is predominantly expressed in the head hypdodermis, neuronal support cells and CAN neurons.
3	ttr-20	F36A4.8	n/a	chrIV 4,246,321	C. elegans TTR-20 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
4	ZK418.3	ZK418.3	n/a	chrIII 7,070,514	contains similarity to Homo sapiens Transmembrane protein 17; ENSEMBL:ENSP00000335094
5	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
6	W02A11.3	W02A11.3	n/a	chrI 12,739,603	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001841 (Zinc finger, RING-type), IPR000694 (Proline-rich region), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
7	ZC168.2	ZC168.2	n/a	chrIV 10,728,759	contains similarity to Pfam domain PF01147 Crustacean CHH/MIH/GIH neurohormone family contains similarity to Interpro domain IPR001166 (Crustacean neurohormone)
8	F20C5.6	F20C5.6	n/a	chrIV 8,772,362	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2DLG0
9	F32H2.6	F32H2.6	n/a	chrI 8,999,077	contains similarity to Pfam domain PF00109 Beta-ketoacyl synthase, N-terminal domain contains similarity to Interpro domains IPR016038 (Thiolase-like, subgroup), IPR000794 (Beta-ketoacyl synthase), IPR014030 (Beta-ketoacyl synthase, N-terminal), IPR016039 (Thiolase-like)
10	ppt-1	F44C4.5	n/a	chrV 6,625,504	ppt-1 encodes the C. elegans palmitoyl protein thioesterase-1 ortholog; by homology PPT-1 is predicted to function in degradation of palmitoylated proteins and ppt-1 mutations result in loss of enzymatic activity from mixed-stage extracts; in C. elegans, ppt-1 activity is essential for mitochondrial organization and biogenesis in neuronal and muscle cells, as well as for proper timing of the onset of both the L4-to-adult molt and egg laying; ppt-1 is also required for normal egg-laying behavior and for a fully normal adult
11	F57A8.1	F57A8.1	n/a	chrV 10,045,776	contains similarity to Interpro domain IPR009058 ()
12	fbxb-71	F40F4.1	n/a	chrX 3,263,537	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
13	C33E10.1	C33E10.1	n/a	chrX 17,305,742	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
14	cut-3	F22B5.3	n/a	chrII 8,445,930	C. elegans CUT-3 protein; contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
15	C55A1.6	C55A1.6	n/a	chrV 15,648,434	contains similarity to Lactococcus lactis Protein maturation protein.; TR:Q9CEV9
16	C06E1.1	C06E1.1	n/a	chrIII 8,606,076	contains similarity to Pfam domain PF03134 TB2/DP1, HVA22 family contains similarity to Interpro domain IPR004345 (TB2/DP1 and HVA22 related protein)
17	skr-21	K08H2.1	n/a	chrX 13,226,159	The skr-21 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-21(RNAi) animals are at least superficially normal.
18	ZK675.4	ZK675.4	n/a	chrII 7,911,649	contains similarity to Homo sapiens Nuclear pore glycoprotein p62; ENSEMBL:ENSP00000305503
19	gpc-1	K02A4.2	n/a	chrX 12,881,921	The gpc-1 gene encodes a heterotrimeric guanine nucleotide-binding protein gamma subunit, expressed specifically in sensory neurons, that is involved in taste adaptation.
20	F53C3.3	F53C3.3	n/a	chrII 3,903,698	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
21	F42A10.6	F42A10.6	n/a	chrIII 6,176,450
22	bath-10	Y49F6C.4	n/a	chrII 3,375,923	C. elegans BATH-10 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
23	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	F40A3.4	F40A3.4	n/a	chrV 7,876,231
25	F23A7.1	F23A7.1	n/a	chrX 16,217,447	contains similarity to Saccharomyces cerevisiae RSC4 is a member of RSC complex, which remodels the structure of chromatin.; SGD:YKR008W
26	F35B3.1	F35B3.1	n/a	chrX 17,016,472	contains similarity to Interpro domain IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
27	C39D10.5	C39D10.5	n/a	chrX 7,891,348
28	glb-27	W01C9.5	n/a	chrII 8,548,030	glb-27 encodes a globin whose expression is probably induced by anoxia in a HIF-1-dependent manner; glb-27 transcription is higher in L3 and dauers than in young adults; glb-27 has no obvious function in mass RNAi assays.
29	F22F7.3	F22F7.3	n/a	chrV 2,113,100	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
30	sdz-3	C29F5.2	n/a	chrII 6,300,414	C. elegans SDZ-3 protein ;
31	F58E6.3	F58E6.3	n/a	chrV 9,748,618	contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07699 (GCC2 and GCC3) (4)contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site)
32	R10H10.4	R10H10.4	n/a	chrIV 10,394,780	contains similarity to Arabidopsis thaliana T15B16.1 protein.; TR:Q9ZSH8
33	srx-85	F38B7.4	n/a	chrV 11,553,428	C. elegans SRX-85 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
34	F39F10.4	F39F10.4	n/a	chrX 16,903,278
35	fbxb-10	T08E11.6	n/a	chrII 1,817,843	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
36	T27E4.1	T27E4.1	n/a	chrV 9,093,497	contains similarity to Interpro domain IPR008973 (C2 calcium/lipid-binding region, CaLB)
37	unc-42	F58E6.10	n/a	chrV 9,766,975	unc-42 encodes a paired-like homeodomain protein of the Q50 class; UNC-42 is required to specify the fate of ASH sensory neurons, AVA, AVD, and AVE interneurons, and a subset of motor neurons; unc-42 mutants fail to express cell-surface receptors required for differentiated neuronal function (sra-6, srb-6, glr-1, glr-5, and glr-6); UNC-42 is also required for AVKR and HSNL growth cones to follow the PVPR and PVQL pioneer axons, for axonal outgrowth in the backward command interneurons AVA, AVD, and AVE, and for inhibition of ectopic FMRFamide-positive and GABAergic axons; unc-42 mutants are defective in mechanosensation, backward motion, and regulation of egg-laying.
38	W10D9.1	W10D9.1	n/a	chrII 454,887
39	fbxb-80	E04A4.2	n/a	chrIV 4,735,325	C. elegans FBXB-80 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
40	C06G3.6	C06G3.6	n/a	chrIV 7,018,898	contains similarity to Pfam domain PF00569 Zinc finger, ZZ type contains similarity to Interpro domains IPR000315 (Zinc finger, B-box), IPR000433 (Zinc finger, ZZ-type)
41	C33A12.4	C33A12.4	n/a	chrIV 9,510,301	contains similarity to Homo sapiens Acidic leucine-rich nuclear phosphoprotein 32 family member E; ENSEMBL:ENSP00000324074
42	F58G1.7	F58G1.7	n/a	chrII 12,945,904	contains similarity to Interpro domain IPR008075 (Lipocalin-1 receptor)
43	med-1	T24D3.1	n/a	chrX 12,430,862	The med-1 gene encodes a GATA-type transcription factor that is an immediate target of maternal SKN-1, and that participates in specifying the mesendoderm.
44	C12D12.3	C12D12.3	n/a	chrX 3,490,216
45	T16A1.2	T16A1.2	n/a	chrII 2,096,988	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
46	pdl-1	C27H5.1	n/a	chrII 7,184,432	C. elegans PDL-1 protein; contains similarity to Pfam domain PF05351 GMP-PDE, delta subunit contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR017287 (Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit), IPR008015 (GMP phosphodiesterase, delta subunit)
47	col-74	ZK1248.2	n/a	chrII 5,831,409	C. elegans COL-74 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domain IPR008160 (Collagen triple helix repeat)
48	vab-7	M142.4	n/a	chrIII 10,923,070	The vab-7 gene encodes an even-skipped-like homeodomain protein that is required for DB motoneuron identity and posterior DB axonal polarity.
49	F10F2.4	F10F2.4	n/a	chrIII 4,624,572	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
50	F08H9.4	F08H9.4	n/a	chrV 14,463,959	F08H9.4 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the excretory canal and ventral nerve-cord neurons), and its expression is only mildly induced by heat shock; however, F08H9.4 expression is increased by heat shock, is induced in a new tissue type (intestine) by heat shock, and probably aids heat shock resistance, since F08H9.4(RNAi) animals die as embryos in heat shock at a higher rate than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.