UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C33D12.2	C33D12.2	0	chrX 3,043,877	C33D12.2 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C33D12.2 may participate in metal homoeostasis; C33D12.2 is expressed in intestine, body wall muscle, nervous system (including ventral and dorsal nerve cords and head neurons), and adult vulval muscle and reproductive system; C33D12.2, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C33D12.2 has no obvious function in RNAi assays.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	B0041.3	B0041.3	n/a	chrI 4,645,153	contains similarity to Pfam domain PF01476 LysM domain contains similarity to Interpro domain IPR002482 (Peptidoglycan-binding LysM)
4	str-178	R11D1.5	n/a	chrV 12,715,427	C. elegans STR-178 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	fbxa-133	C38D9.4	n/a	chrV 17,585,301	C. elegans FBXA-133 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
6	C32B5.13	C32B5.13	n/a	chrII 961,636	contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000668 (Peptidase C1A, papain C-terminal)
7	VC5.2	VC5.2	n/a	chrV 7,087,384	contains similarity to Pfam domain PF00053 Laminin EGF-like (Domains III and V) contains similarity to Interpro domains IPR006056 (YjgF-like protein), IPR006210 (EGF), IPR002049 (EGF-like, laminin)
8	EEED8.12	EEED8.12	n/a	chrII 5,408,624	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
9	R11G1.1	R11G1.1	n/a	chrX 3,663,173	contains similarity to Pfam domain PF00057 Low-density lipoprotein receptor domain class A contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
10	C31B8.12	C31B8.12	n/a	chrV 2,926,103	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
11	H22K11.3	H22K11.3	n/a	chrX 6,783,682	contains similarity to Candida albicans Hyphally-regulated protein precursor.; SW:P46591
12	C37E2.3	C37E2.3	n/a	chrX 14,180,268	contains similarity to Pfam domain PF04750 FAR-17a/AIG1-like protein contains similarity to Interpro domains IPR006838 (FAR-17a/AIG1-like protein), IPR002208 (SecY protein)
13	R06B9.4	R06B9.4	n/a	chrII 13,754,197	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
14	C07A9.12	C07A9.12	n/a	chrIII 9,726,313	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
15	F13B12.3	F13B12.3	n/a	chrIV 10,441,433	contains similarity to Tetraodon nigroviridis Chromosome 12 SCAF8721, whole genome shotgun sequence. (Fragment).; TR:Q4T6K3
16	srh-185	C50H11.7	n/a	chrV 3,066,861	C. elegans SRH-185 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR004090 (Chemotaxis methyl-accepting receptor)
17	srm-1	T28H11.2	n/a	chrIV 5,013,566	C. elegans SRM-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
18	gcy-4	ZK970.5	n/a	chrII 10,306,418	gcy-4 encodes a predicted transmembrane guanylyl cyclase; by homology, GCY-4 may function as a chemosensory receptor; however, as loss of gcy-4 activity via mutation or large-scale RNAi screens results in no obvious abnormalities, the precise role of gcy-4 in C. elegans development and/or behavior is not yet known; the sole gcy-4 ::GFP reporter construct reported to date did not produce any specific GFP signals.
19	gcy-34	M04G12.3	n/a	chrV 13,384,440	gcy-34 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-34 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-34 in C. elegans development and/or behavior is not yet known; GCY-34 expression in neurons connected to the pseudocoelom suggests, however, that GCY-34 may play a role in fluid homeostasis.
20	F38A1.6	F38A1.6	n/a	chrIV 1,252,165
21	rog-1	F54D12.6	n/a	chrII 1,374,343	rog-1 encodes a protein with an insulin receptor substrate-1 (IRS-type) phosphotyrosine-binding (PTB) domain that is required for the progression from pachytene to diakinesis in meiosis; rog-1 is primarily transcribed in germ cells, and this expression is required for oocyte development; ROG-1 is orthologous to human FRS2 (OMIM:607743) and FRS3 (OMIM:607744); rog-1(tm1031) mutant oocytes fail to progress from pachytene to diakinesis, a phenotype reminiscent of let-60 or mpk-1 mutant oocytes, and rog-1(tm1031) gonads lack phosphorylated MPK-1; rog-1(tm1031) and rog-1(RNAi) hermaphrodites show reduced brood sizes and increased embryonic lethality, with rog-1(tm1031) being more phenotypically severe than rog-1(RNAi); rog-1(tm1031) germ cell, brood size, and MPK-1 phosphorylation phenotypes are suppressed by the gain-of-function mutations let-60(n1046) or let-60(ga89ts); during meiosis, ROG-1 may function as an adaptor downstream of LET-23 and upstream of LET-60.
22	ndx-3	Y38A8.1	n/a	chrII 4,954,109	The ndx-3 gene encodes a homolog of peroxisomal CoA diphosphatases in both S. cerevisiae (PCD1) and C. elegans (NDX-8); more generally, NDX-3 protein belongs to the family of NUDIX hydrolases.
23	Y75B8A.14	Y75B8A.14	n/a	chrIII 12,217,589	contains similarity to Pfam domain PF03029 Conserved hypothetical ATP binding protein contains similarity to Interpro domain IPR004130 (Protein of unknown function, ATP binding)
24	VW02B12L.2	VW02B12L.2	n/a	chrII 11,439,443	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
25	C12D5.10	C12D5.10	n/a	chrV 7,692,770	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
26	F29D10.2	F29D10.2	n/a	chrI 8,842,038	contains similarity to Interpro domains IPR000853 (Nematoda metallothionein, family 6), IPR000006 (Metallothionein, vertebrate), IPR002952 (Eggshell protein), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR001396 (Echinodermata metallothionein, family 4), IPR001008 (Mollusc metallothionein, family 2)
27	math-2	C08F1.1	n/a	chrII 1,799,617	C. elegans MATH-2 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
28	fpn-1.3	R08F11.6	n/a	chrV 3,796,213	C. elegans FPN-1.3 protein; contains similarity to Pfam domain PF06963 Ferroportin1 (FPN1) contains similarity to Interpro domains IPR009716 (Ferroportin1), IPR016196 (MFS general substrate transporter)
29	clec-21	T07H3.4	n/a	chrII 1,583,563	C. elegans CLEC-21 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
30	K06H6.1	K06H6.1	n/a	chrV 588,891	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
31	bli-5	F45G2.5	n/a	chrIII 13,428,598	bli-5 encodes a protease inhibitor that affects the integrity of the cuticle and the development of the bursa in the adult male.
32	srh-15	C50B6.6	n/a	chrV 13,321,651	C. elegans SRH-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	str-16	Y73C8A.1	n/a	chrV 3,239,764	C. elegans STR-16 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
34	B0391.3	B0391.3	n/a	chrV 15,616,248	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000802 (Arsenical pump membrane protein)
35	Y17D7C.2	Y17D7C.2	n/a	chrV 18,717,931	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
36	tbx-31	C36C9.2	n/a	chrX 1,672,652	tbx-31 encodes a diverged member of the T-box transcription factor family; by homology, TBX-31 is predicted to function as a transcriptional regulator during development, but as loss of tbx-31 activity via RNAi results in no obvious defects, the precise role of TBX-31 in C. elegans development and/or behavior is not yet known.
37	K02F3.8	K02F3.8	n/a	chrIII 838,968
38	R11G11.3	R11G11.3	n/a	chrV 531,412	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
39	T21E12.2	T21E12.2	n/a	chrI 4,414,499	contains similarity to Interpro domain IPR006162 (Phosphopantetheine attachment site)
40	F58B6.1	F58B6.1	n/a	chrIII 1,114,111	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domain IPR002921 (Lipase, class 3)
41	srj-1	ZK829.8	n/a	chrIV 11,964,638	C. elegans SRJ-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	str-225	C07G3.6	n/a	chrV 3,508,534	C. elegans STR-225 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001307 (Thiosulphate sulphurtransferase, conserved site)
43	lin-11	ZC247.3	n/a	chrI 10,251,797	lin-11 encodes a predicted LIM homeodomain transcription factor that affects vulval development, neuronal development and fate specification, utse cell differentiation, and fertility; it is expressed in some neurons, the vulva, pi cells and their progeny, and the spermatheca.
44	C32B5.9	C32B5.9	n/a	chrII 955,198
45	F22H10.5	F22H10.5	n/a	chrX 16,687,280	contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
46	K09A11.5	K09A11.5	n/a	chrX 13,277,067	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
47	F55G1.12	F55G1.12	n/a	chrIV 7,494,554	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
48	Y39A1A.20	Y39A1A.20	n/a	chrIII 10,699,807
49	fbxa-57	C29F9.10	n/a	chrIII 106,751	C. elegans FBXA-57 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001986 (3-phosphoshikimate 1-carboxyvinyltransferase, core), IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
50	C46H3.3	C46H3.3	n/a	chrX 1,228,487	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)