UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C33A12.4	C33A12.4	2e-32	chrIV 9,510,301	contains similarity to Homo sapiens Acidic leucine-rich nuclear phosphoprotein 32 family member E; ENSEMBL:ENSP00000324074
2	F53A9.4	F53A9.4	n/a	chrX 8,705,694
3	F40A3.4	F40A3.4	n/a	chrV 7,876,231
4	rab-28	Y11D7A.4	n/a	chrIV 9,243,090	rab-28 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; the precise biological role and expression pattern of rab-28 are not yet known.
5	T25B6.4	T25B6.4	n/a	chrX 9,016,157
6	gpc-1	K02A4.2	n/a	chrX 12,881,921	The gpc-1 gene encodes a heterotrimeric guanine nucleotide-binding protein gamma subunit, expressed specifically in sensory neurons, that is involved in taste adaptation.
7	F58B4.4	F58B4.4	n/a	chrV 10,931,009	contains similarity to Plasmodium yoelii Rhoptry protein.; TR:Q26216
8	arl-3	F19H8.3	n/a	chrII 14,607,534	arl-3 encodes a member of the ARL (ADP-ribosylation factor(ARF)-like) family of proteins which are very similar to ARF proteins but lack the ability to stimulate ADP ribosylation by cholera toxin; as loss of arl-3 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ARL-3 is not yet known.
9	C12D12.3	C12D12.3	n/a	chrX 3,490,216
10	pdl-1	C27H5.1	n/a	chrII 7,184,432	C. elegans PDL-1 protein; contains similarity to Pfam domain PF05351 GMP-PDE, delta subunit contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR017287 (Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit), IPR008015 (GMP phosphodiesterase, delta subunit)
11	Y37H2C.1	Y37H2C.1	n/a	chrV 18,275,256	contains similarity to Homo sapiens SIDT1 protein; ENSEMBL:ENSP00000377416
12	fbxb-80	E04A4.2	n/a	chrIV 4,735,325	C. elegans FBXB-80 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
13	F32H2.6	F32H2.6	n/a	chrI 8,999,077	contains similarity to Pfam domain PF00109 Beta-ketoacyl synthase, N-terminal domain contains similarity to Interpro domains IPR016038 (Thiolase-like, subgroup), IPR000794 (Beta-ketoacyl synthase), IPR014030 (Beta-ketoacyl synthase, N-terminal), IPR016039 (Thiolase-like)
14	F10E7.9	F10E7.9	n/a	chrII 7,108,173	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domain IPR004841 (Amino acid permease-associated region)
15	R05A10.7	R05A10.7	n/a	chrIV 14,161,499	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
16	F22F7.3	F22F7.3	n/a	chrV 2,113,100	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
17	T22B7.4	T22B7.4	n/a	chrX 5,639,932	contains similarity to Pfam domain PF07039 Protein of unknown function (DUF1325) contains similarity to Interpro domain IPR010750 (Protein of unknown function DUF1325)
18	F19G12.1	F19G12.1	n/a	chrX 1,431,242	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
19	W03B1.8	W03B1.8	n/a	chrIV 4,344,287	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
20	F58E6.1	F58E6.1	n/a	chrV 9,742,698	n/a
21	hot-5	K07A12.6	n/a	chrI 8,685,157	hot-5 encodes a predicted membrane-associated protein that is a member of the Ly-6 superfamily of glycosylphosphatidylinositol (GPI)-linked signaling proteins and is homologous to ODR-2, a neuronally expressed protein required for olfaction; as loss of hot-5 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HOT-5 in C. elegans development and/or behavior is not yet known.
22	ifta-2	T28F3.6	n/a	chrIV 17,301,376	ifta-2 encodes a ciliary protein, orthologous to human RABL5, that is required for normally short life span and dauer formation; IFTA-2 is expressed in amphid, labial, and phasmid ciliated sensory neurons; intracellularly, IFTA-2 resides in the bases and axonemes of cilia, colocalizing with DAF-2 and AGE-1; IFTA-2 may be either a cargo or a cargo-docking component of intraflagellar transport (IFT) by the IFT-B complex; ciliary basal localization of IFTA-2 is abolished by a T42N mutation predicted to lock ITFA-2 into an inactive, GDP-bound conformation; ifta-2(tm1724) mutants have abnormally long lifespans and constitutive dauer formation, perhaps because IFTA-2 regulates DAF-2 signalling from ciliated sensory neurons; IFTA-2 is not required for cilium assembly or IFT, nor is it required for chemosensation or osmosensation; the ciliary localization of IFTA-2 is conserved in RABL5; via an X-box in its promoter, ifta-2 is a candidate for direct regulation by DAF-19.
23	gst-8	F11G11.1	n/a	chrII 4,884,139	gst-8 encodes a predicted glutathione S-transferase.
24	srj-13	R13D7.3	n/a	chrV 7,403,263	C. elegans SRJ-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	Y43F8A.1	Y43F8A.1	n/a	chrV 19,370,930	contains similarity to Rhizobium sp Probable conjugal transfer protein trbD.; SW:TRBD_RHISN
26	C39D10.5	C39D10.5	n/a	chrX 7,891,348
27	T26E4.3	T26E4.3	n/a	chrV 15,783,606	contains similarity to Pfam domain PF01531 (Glycosyl transferase family 11)
28	F35B3.1	F35B3.1	n/a	chrX 17,016,472	contains similarity to Interpro domain IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
29	srx-85	F38B7.4	n/a	chrV 11,553,428	C. elegans SRX-85 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
30	srbc-10	C18B10.2	n/a	chrV 7,492,430	C. elegans SRBC-10 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
31	C55A1.7	C55A1.7	n/a	chrV 15,647,283	contains similarity to Escherichia coli TolA protein.; SW:TOLA_ECOLI
32	F58G1.7	F58G1.7	n/a	chrII 12,945,904	contains similarity to Interpro domain IPR008075 (Lipocalin-1 receptor)
33	clec-139	F35D11.10	n/a	chrII 4,620,939	C. elegans CLEC-139 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
34	F47B10.8	F47B10.8	n/a	chrX 10,905,841	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
35	xbx-3	M04D8.6	n/a	chrIII 10,036,315	C. elegans XBX-3 protein ;
36	T07D10.1	T07D10.1	n/a	chrI 12,604,999	contains similarity to Strongylocentrotus purpuratus Katanin p80 subunit.; TR:O61585
37	Y42A5A.4	Y42A5A.4	n/a	chrV 11,106,364	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
38	T19D7.7	T19D7.7	n/a	chrX 678,427	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
39	F02H6.5	F02H6.5	n/a	chrIV 14,222,125	contains similarity to Pfam domain PF07992 Pyridine nucleotide-disulphide oxidoreductase contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR015904 (Sulphide quinone-reductase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
40	Y8A9A.4	Y8A9A.4	n/a	chrII 3,791,066
41	dyf-5	M04C9.5	n/a	chrI 9,360,991	dyf-5 encodes a putative MAP kinase orthologous to human MAK/ICK (OMIM:154235), Chlamydomonas reinhardtii LF4, and Leishmania mexicana MPK9; DYF-5 negatively regulates cilial length, restricts KAP-1 to middle ciliary segments, is required for normal localization of six IFT components, and is required for OSM-3 to comigrate normally with IFT particles; DYF-5 is also required for dye-filling of amphid and phasmid neurons and for normal chemotaxis, dauer formation, and male mating; DYF-5 is expressed in head neurons (including amphid neurons), tail neurons (including phasmid neurons), CAN cells, excretory canal neurons, posterior lateral ganglion neurons and in many male tail cells; dyf-5 mutant cilia are abnormally elongated, either failing to enter the amphid channel or accumulating IFT proteins at their distal ends, whereas DYF-5 overexpression results in truncated cilia; the dyf-5 promoter region contains an X-box, predicted to be bound and transcriptionally activated by DAF-19, and dyf-5 is regulated by DAF-19 in vivo; dyf-5 animals are slightly shorter than normal.
42	T05B4.9	T05B4.9	n/a	chrV 4,117,993	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
43	C16D9.3	C16D9.3	n/a	chrV 8,239,232
44	srh-300	Y94A7B.6	n/a	chrV 17,822,964	C. elegans SRH-300 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	F59D6.1	F59D6.1	n/a	chrV 3,051,786
46	F36D4.4	F36D4.4	n/a	chrV 9,404,118	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000832 (GPCR, family 2, secretin-like), IPR000276 (GPCR, rhodopsin-like)
47	F08G2.4	F08G2.4	n/a	chrII 13,830,819	contains similarity to Interpro domain IPR001399 (VP6 blue-tongue virus inner capsid protein)
48	tkr-1	C38C10.1	n/a	chrIII 9,386,535	tkr-1 encodes a G protein-coupled receptor that is the C. elegans tachykinin-like neuropeptide receptor homolog; by homology, TKR-1 is predicted to function in modulation of excitatory neurotransmission; as loss of tkr-1 activity via RNAi results in moderate reduction of fat content, TKR-1 may play a specific role in regulating lipid metabolism; a tkr-1 reporter gene fusion is reportedly expressed in the socket cells of the deirid and post-deirid sensilla from the L2 larval stage through adulthood.
49	ZC239.3	ZC239.3	n/a	chrII 3,216,335	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
50	ZC84.4	ZC84.4	n/a	chrIII 9,211,781	ZC84.4 encodes a G protein-coupled receptor with acidic amino acids in the -3 position of its PDZ binding motif; ZC84.4 protein binds PDZ domain 10 of the multi-PDZ domain protein, MPZ-1, in GST pulldown experiments; by analogy with SER-1, the PDZ binding motif of ZC84.4 may enhance its signalling.