UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sru-1	C33A12.14	0	chrIV 9,489,409	C. elegans SRU-1 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	W04G3.5	W04G3.5	n/a	chrX 11,074,823	contains similarity to Pfam domain PF00156 Phosphoribosyl transferase domain contains similarity to Interpro domains IPR005946 (Phosphoribosyl pyrophosphokinase), IPR000836 (Phosphoribosyltransferase)
4	unc-33	Y37E11C.1	n/a	chrIV 3,521,708	unc-33 encodes a conserved member of the CRMP/TOAD/Ulip/DRP family of proteins that includes mammalian CRMP-2 (Collapsin response mediator protein-2), which is essential for axon guidance and axonogenesis; in C. elegans, unc-33 activity is required for several biological processes including outgrowth and guidance of sensory, motor, and interneurons, sex myoblast migration, normal body movement and morphology, egg laying, and defecation; by homology to CRMP-2, UNC-33 is predicted to bind tubulin heterodimers and promote microtubule assembly, thereby regulating the extension and branching of cellular projections during neuronal polarization; UNC-33 is reportedly expressed exclusively in axonal processes from after early embryogenesis through larval and adult stages.
5	ZK938.2	ZK938.2	n/a	chrII 9,837,617	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
6	dylt-2	D1009.5	n/a	chrX 8,939,705	dylt-2 encodes a small putative dynein light chain subunit orthologous to human CTEX1D1, LOC343521, and TCTE3; unlike its distant paralog DYLT-1, DYLT-2 does not obviously inhibit DHC-1 in vivo; DYTL-2 has no obvious function in mass RNAi assays.
7	pmk-1	B0218.3	n/a	chrIV 8,149,748	pmk-1 encodes a mitogen-activated protein kinase (MAPK), orthologous to human p38 MAPK (OMIM:600289), that is required for eliciting gonadal programmed cell death in response to Salmonella enterica infection; PMK-1 lies upstream of CED-9, a negative regulator of apoptosis, in the programmed cell death pathway.
8	F54H5.5	F54H5.5	n/a	chrII 6,625,330
9	F57B10.9	F57B10.9	n/a	chrI 6,551,594	F57B10.9 is orthologous to the human gene SPARTIN (TAHCCP1; OMIM:607111), which when mutated leads to disease.
10	T06A1.1	T06A1.1	n/a	chrV 1,924,364	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
11	srz-54	Y102A5C.25	n/a	chrV 16,981,243	C. elegans SRZ-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
12	mog-4	C04H5.6	n/a	chrII 14,556,957	The mog-4 gene encodes a DEAH helicase orthologous to the Drosophila CG10689 and the S. cerevisiae PRP2 proteins.
13	fbxa-144	F44G3.8	n/a	chrV 16,132,206	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
14	dgk-3	F54G8.2	n/a	chrIII 9,165,462	dgk-3 encodes a diacylglycerol kinase that is the C. elegans ortholog of mammalian DGK-beta; dgk-3 activity is required for regulation of long-term thermotactic behavioral plasticity and for regulation of olfactory adaptation; large-scale expression studies have reported dgk-3 expression in head neurons, the intestine, and the pharyngeal lumen, while expression profiling indicates that dgk-3 is expressed in the AFD thermosensory neurons as well as a small number of additional sensory neurons.
15	sulp-1	C55B7.6	n/a	chrI 6,484,156	sulp-1 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-1 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-1::GFP transcriptional fusion is expressed strongly in several neurons, weakly in hypodermal cells and the intestine, and very faintly in the excretory cell and body wall muscle.
16	tag-173	F27D4.5	n/a	chrI 7,728,166	tag-173/F27D4.5 is orthologous to the human gene BRANCHED CHAIN KETO ACID DEHYDROGENASE E1, ALPHA POLYPEPTIDE (BCKDHB; OMIM:248600), which when mutated leads to maple syrup urine disease, type 1a; F27D4.5 protein is predicted to be mitochondrial.
17	ZK643.1	ZK643.1	n/a	chrIII 8,934,736	contains similarity to Pfam domain PF00339 Arrestin (or S-antigen), N-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011021 (Arrestin-like, N-terminal)
18	Y56A3A.28	Y56A3A.28	n/a	chrIII 11,966,536	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
19	F52H2.4	F52H2.4	n/a	chrX 2,546,392	contains similarity to Pfam domain PF00474 Sodium:solute symporter family contains similarity to Interpro domains IPR010979 (Ribosomal protein S13-like, H2TH), IPR001734 (Na+/solute symporter)
20	ceh-20	F31E3.1	n/a	chrIII 6,980,772	ceh-20 encodes the C. elegans ortholog of the homeodomain co-factor Extradenticle (Exd/Pbx); together with ceh-40 and unc-62, ceh-20 activity is required for embryonic viability; ceh-20 is also required as a cofactor for LIN-39- and MAB-5- dependent postembryonic mesoderm patterning; in addition, ceh-20 is required for regulating post-embryonic migrations of the Q neuroblast descendants and for regulating vulval development; a CEH-20::GFP fusion protein is expressed in embryos and postembryonically in many cell types including the Q, P, and V cells and their descendants; CEH-20 localizes to the nucleus.
21	C35E7.3	C35E7.3	n/a	chrI 10,837,920
22	fbxb-11	F45C12.5	n/a	chrII 1,725,771	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
23	T12A2.2	T12A2.2	n/a	chrIII 6,249,889	contains similarity to Pfam domain PF02516 Oligosaccharyl transferase STT3 subunit contains similarity to Interpro domains IPR001036 (Acriflavin resistance protein), IPR003674 (Oligosaccharyl transferase, STT3 subunit)
24	dnj-23	T24H10.3	n/a	chrII 9,107,885	This gene encodes a protein containing a DnaJ ('J') domain.
25	C18A3.3	C18A3.3	n/a	chrII 5,717,142	contains similarity to Pfam domain PF05890 Eukaryotic rRNA processing protein EBP2 contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR008610 (Eukaryotic rRNA processing)
26	F09E5.10	F09E5.10	n/a	chrII 5,349,294	contains similarity to Interpro domain IPR009079 (Four-helical cytokine-like, core)
27	ceh-39	T26C11.7	n/a	chrX 1,855,047	ceh-39 encodes a a ONECUT class CUT homeobox protein with a single N-terminal cut domain; CEH-39 acts as an X-signal element (XSE) to affect sex determination; the cut domain may be a compact DNA-binding domain composed of alpha helices; ceh-39 is one of three nematode-specific ONECUT genes in a cluster with ceh-21 and ceh-41.
28	F29D11.2	F29D11.2	n/a	chrI 7,637,136	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
29	rgef-1	F25B3.3	n/a	chrV 9,559,135	rgef-1 encodes a Ca2+-regulated Ras nucleotide exchange factor orthologous to human Ras guanyl-releasing protein (RasGRP); rgef-1 reporter fusions are expressed in post-mitotic neurons (pan-neuronally) beginning at the late comma stage of embryogenesis.
30	nhr-103	F44C8.4	n/a	chrV 2,226,236	nhr-103 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
31	str-160	ZK697.10	n/a	chrV 1,735,727	C. elegans STR-160 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	srh-140	Y6E2A.6	n/a	chrV 15,723,067	C. elegans SRH-140 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000484 (Photosynthetic reaction centre, L and M subunits)
33	cyp-33C1	C45H4.2	n/a	chrV 2,180,672	C. elegans CYP-33C1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
34	ZC204.14	ZC204.14	n/a	chrII 1,662,200
35	C41H7.5	C41H7.5	n/a	chrII 3,003,154	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
36	F28G4.2	F28G4.2	n/a	chrV 16,281,423	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
37	str-43	T23D5.9	n/a	chrV 15,751,514	C. elegans STR-43 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	lgc-49	K10D6.1	n/a	chrV 11,192,427	C. elegans LGC-49 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR001390 (Gamma-aminobutyric-acid A receptor, alpha subunit), IPR002289 (Gamma-aminobutyric-acid A receptor, beta subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
39	ceh-40	F17A2.5	n/a	chrX 12,319,393	ceh-40 encodes one of two C. elegans homeodomain proteins homologous to Extradenticle (Exd/Pbx); ceh-40 genetically interacts with ceh-20 and unc-62 during embryonic development: while loss of ceh-40 activity alone results in no significant embryonic lethality, loss of ceh-40 and ceh-20, or ceh-40, ceh-20, and unc-62, results in incompletely penetrant embryonic lethality.
40	aco-1	ZK455.1	n/a	chrX 11,341,447	aco-1 encodes an aconitase that is homologous to mammalian iron regulatory protein-1 (IRP1); aco-1 activity is required for normal brood sizes and, under iron stress conditions, for normal lifespan and L4-to-adult growth rates; ACO-1 physically interacts with GEX-3; like IRP1, ACO-1 has aconitase activity and is post-translationally regulated by iron, but, unlike IRP1, it lacks RNA-binding activity; ACO-1 is predicted to be mitochondrial, and its mRNA levels appear to decrease in response to iron treatment.
41	sru-28	C38C3.1	3e-62	chrV 1,507,196	C. elegans SRU-28 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
42	K02F3.2	K02F3.2	n/a	chrIII 848,051	The K02F3.2 gene encodes a homolog of human SLC25A13, which when mutated leads to adult onset type II citrullinaemia (OMIM:603471).
43	mbf-1	H21P03.1	n/a	chrIV 11,479,744	C. elegans MBF-1 protein; contains similarity to Pfam domains PF01381 (Helix-turn-helix) , PF08523 (Multiprotein bridging factor 1) contains similarity to Interpro domains IPR010982 (Lambda repressor-like, DNA-binding), IPR013729 (Multiprotein bridging factor 1, N-terminal), IPR001387 (Helix-turn-helix type 3)
44	clec-9	Y70C5C.2	n/a	chrV 16,705,835	C. elegans CLEC-9 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
45	Y48E1B.5	Y48E1B.5	n/a	chrII 13,571,494	contains similarity to Onchocerca volvulus Novel immunogenic protein NIP-2.; TR:Q9NJD6
46	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
47	C37A2.6	C37A2.6	n/a	chrI 6,788,535	contains similarity to Pfam domain PF06325 Ribosomal protein L11 methyltransferase (PrmA) contains similarity to Interpro domain IPR010456 (Ribosomal L11 methyltransferase)
48	H37N21.1	H37N21.1	n/a	chrI 7,143,753	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001397 (5-Hydroxytryptamine 5A receptor), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
49	tag-50	M176.1	n/a	chrII 9,413,277	tag-50 encodes a predicted member of the arrestin family.
50	F26D2.13	F26D2.13	n/a	chrV 16,435,139	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)