UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C32H11.11	C32H11.11	9e-98	chrIV 12,938,618	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	rpn-12	ZK20.5	n/a	chrII 11,653,526	rpn-12 is predicted to encode a non-ATPase subunit of the 19S regulatory complex of the proteasome that interacts with NHR-6 in yeast two-hybrid assays.
5	C50E3.6	C50E3.6	n/a	chrV 7,589,517
6	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
7	ZC84.1	ZC84.1	n/a	chrIII 9,203,077	contains similarity to Pfam domains PF01683 (EB module) (3), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (5)contains similarity to Interpro domains IPR011052 (Proteinase and amylase inhibitor), IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat), IPR001762 (Blood coagulation inhibitor, Disintegrin), IPR013032 (EGF-like region, conserved site), IPR006149 (Nematode-specific EB region)
8	H37A05.1	H37A05.1	n/a	chrV 13,652,199	H37A05.1 encodes a putative phosphatidic acid phosphatase orthologous to budding yeast PAH1 and human LPIN1 (OMIM:605518), LPIN2 (OMIM:605519, mutated in Majeed syndrome), and LPIN3 (OMIM:605520); H37A05.1 is expressed in vulval muscle; in mass RNAi assays, H37A05.1 is required for the osmotic integrity of eggs and for normal larval growth, body thickness, locomotion, and fertility; by orthology, H37A05.1 is expected to be dephosphorylated by SCPL-2.
9	let-70	M7.1	n/a	chrIV 11,081,640	let-70 encodes a class I E2 ubiquitin conjugating enzyme; let-70 was identified in screens for essential genes and phenotypic analyses indicate that loss of let-70 activity results in embryonic and larval lethality with defects in sarcomere assembly; purified LET-70 can stimulate the self-ubiquitylation activities of CHN-1 and UFD-2, E4 ubiquitin conjugation factors and, in addition, can stimulate the CHN-1- and UFD-2-dependent multiubiquitylation of UNC-45, a myosin-directed chaperone; in this manner, LET-70 may regulate UNC-45 degradation and myosin assembly; RNA blot analyses and a let-70-lacZ reporter fusion reveal that let-70 is abundantly expressed at all stages of development, including the dauer larval stage; strong staining is observed in most somatic tissues until adult stages, when expression generally becomes restricted to the nervous system.
10	col-73	F11G11.12	n/a	chrII 4,872,607	C. elegans COL-73 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR000596 (Cholecystokinin receptor, type A), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
11	K05C4.8	K05C4.8	n/a	chrI 14,732,974	contains similarity to Dictyostelium discoideum Sterol glucosyltransferase (EC 2.4.1.173).; TR:Q9XYD4
12	ZK1225.1	ZK1225.1	n/a	chrI 13,206,699	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
13	R11G10.2	R11G10.2	n/a	chrV 13,513,568	contains similarity to Pfam domain PF05694 56kDa selenium binding protein (SBP56) contains similarity to Interpro domain IPR008826 (Selenium-binding protein)
14	ndx-9	F13H10.2	n/a	chrIV 11,010,995	The ndx-9 gene encodes a member of the NADH pyrophosphatase subfamily of the NUDIX hydrolases.
15	F21G4.3	F21G4.3	n/a	chrX 9,896,105	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
16	ZK829.7	ZK829.7	n/a	chrIV 11,960,692	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
17	F44D12.1	F44D12.1	n/a	chrIV 10,012,047	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domains IPR008144 (Guanylate kinase), IPR008145 (Guanylate kinase/L-type calcium channel region), IPR001452 (Src homology-3), IPR001478 (PDZ/DHR/GLGF)
18	W06A11.1	W06A11.1	n/a	chrII 4,068,658
19	C47A4.1	C47A4.1	n/a	chrIV 13,716,255	contains similarity to Interpro domain IPR015609 (Molecular chaperone, heat shock protein, Hsp40, DnaJ)
20	C26B2.7	C26B2.7	n/a	chrIV 8,016,527
21	F55A4.1	F55A4.1	n/a	chrX 1,036,270	contains similarity to Pfam domain PF00957 Synaptobrevin contains similarity to Interpro domains IPR010908 (Longin), IPR011012 (Longin-like), IPR001388 (Synaptobrevin)
22	clec-21	T07H3.4	n/a	chrII 1,583,563	C. elegans CLEC-21 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	F35F10.4	F35F10.4	n/a	chrV 3,292,977	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
24	mtl-2	T08G5.10	n/a	chrV 14,018,435	mtl-2 encodes one of two C. elegans metallothioneins, small, cysteine-rich, metal-binding proteins; MTL-2 functions in metal detoxification and homeostasis and stress adaptation; in addition, mtl-2 plays a role in regulating growth and fertility; mtl-2 expression is induced in larval and adult intestinal cells following exposure to cadmium or heat shock; MTL-2 intestinal expression is dependent upon ELT-2, an intestine-specific GATA-type transcription factor; mtl-2 is downregulated by DAF-16 in daf-2 mutants.
25	F55D12.2	F55D12.2	n/a	chrI 7,892,099	contains similarity to Interpro domains IPR002017 (Spectrin repeat), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal)
26	ZK1290.5	ZK1290.5	n/a	chrII 7,530,168	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
27	his-1	T10C6.14	n/a	chrV 16,042,648	his-1 encodes an H4 histone; his-1 is contained within the histone gene cluster HIS1; transcript analysis suggests that it encodes the major class of H4 transcripts.
28	col-153	F17C11.3	n/a	chrV 10,950,773	C. elegans COL-153 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
29	T05C1.3	T05C1.3	n/a	chrII 4,488,577
30	F33H12.1	F33H12.1	n/a	chrII 2,601,167	contains similarity to Pfam domain PF00533 BRCA1 C Terminus (BRCT) domain contains similarity to Interpro domain IPR001357 (BRCT)
31	bli-5	F45G2.5	n/a	chrIII 13,428,598	bli-5 encodes a protease inhibitor that affects the integrity of the cuticle and the development of the bursa in the adult male.
32	Y32B12C.3	Y32B12C.3	n/a	chrV 16,613,751	contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
33	C02F5.3	C02F5.3	n/a	chrIII 8,246,494	contains similarity to Pfam domains PF01926 (GTPase of unknown function) , PF02824 (TGS domain) contains similarity to Interpro domains IPR005225 (Small GTP-binding protein), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG), IPR004095 (TGS), IPR006074 (GTP1/OBG, conserved site)
34	B0222.9	B0222.9	n/a	chrV 9,170,672	contains similarity to Pfam domains PF00941 (FAD binding domain in molybdopterin dehydrogenase) , PF02738 (Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain) , PF00111 (2Fe-2S iron-sulfur cluster binding domain) , PF01799 ([2Fe-2S] binding domain) , PF01315 (Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR001041 (Ferredoxin), IPR002346 (Molybdopterin dehydrogenase, FAD-binding), IPR012675 (Beta-grasp fold, ferredoxin-type), IPR002888 ([2Fe-2S]-binding), IPR016166 (FAD-binding, type 2), IPR006058 (2Fe-2S ferredoxin, iron-sulphur binding site), IPR016169 (CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2), IPR000674 (Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead), IPR008274 (Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)
35	W04G3.2	W04G3.2	n/a	chrX 11,063,262	contains similarity to Saccharomyces cerevisiae Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes; SGD:YGR097W
36	C50H11.1	C50H11.1	n/a	chrV 3,090,166	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
37	R09D1.8	R09D1.8	n/a	chrII 9,460,970	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
38	gcy-34	M04G12.3	n/a	chrV 13,384,440	gcy-34 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-34 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-34 in C. elegans development and/or behavior is not yet known; GCY-34 expression in neurons connected to the pseudocoelom suggests, however, that GCY-34 may play a role in fluid homeostasis.
39	W08D2.5	W08D2.5	n/a	chrIV 9,821,001	contains similarity to Pfam domains PF00122 (E1-E2 ATPase) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR008250 (E1-E2 ATPase-associated region), IPR006544 (P-type ATPase of unknown pump specificity (type V)), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR000150 (Cof protein), IPR005834 (Haloacid dehalogenase-like hydrolase)
40	F59F4.2	F59F4.2	n/a	chrX 15,841,893	contains similarity to Pfam domain PF06624 Ribosome associated membrane protein RAMP4 contains similarity to Interpro domain IPR010580 (Ribosome associated membrane RAMP4)
41	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
42	C25F9.9	C25F9.9	n/a	chrV 19,417,227	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IE25
43	F39H12.3	F39H12.3	n/a	chrX 839,898	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) (3), PF02197 (Regulatory subunit of type II PKA R-subunit) contains similarity to Interpro domains IPR003117 (cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta), IPR000048 (IQ calmodulin-binding region)
44	K04F10.7	K04F10.7	n/a	chrI 6,367,224	contains similarity to Homo sapiens Isoform 1 of Protein FAM76B; ENSEMBL:ENSP00000351631
45	Y39A1A.20	Y39A1A.20	n/a	chrIII 10,699,807
46	C45G9.7	C45G9.7	n/a	chrIII 5,046,619	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domains IPR017268 (Tax1-binding protein 3), IPR001478 (PDZ/DHR/GLGF)
47	C50F7.6	C50F7.6	n/a	chrIV 7,721,871	contains similarity to Homo sapiens Isoform 4 of PDZ domain-containing RING finger protein 4; ENSEMBL:ENSP00000370169
48	dop-4	C52B11.3	n/a	chrX 1,296,964	C. elegans DOP-4 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000929 (Dopamine receptor), IPR002233 (Adrenergic receptor), IPR001671 (Melanocortin/ACTH receptor), IPR000995 (Muscarinic acetylcholine receptor), IPR000276 (GPCR, rhodopsin-like)
49	F29C12.3	F29C12.3	n/a	chrII 13,107,433	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
50	srw-61	H25K10.7	n/a	chrIV 16,237,697	C. elegans SRW-61 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor)