UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C32B5.11	C32B5.11	9.999999999999999e-64	chrII 949,051
2	clec-10	C03H5.1	n/a	chrII 403,400	C. elegans CLEC-10 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
3	ubc-22	C06E2.7	n/a	chrX 8,868,414	ubc-22 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae UBC8 and human UBC1/HIP2 (Huntingtin interacting protein 2, OMIM:602846) which are involved in regulating fructose-1,6-bisphosphatase and huntingtin catabolism, respectively; by homology, UBC-22 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-22 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-22 in C. elegans development and/or behavior is not yet known.
4	nhr-17	C02B4.2	n/a	chrX 12,665,768	nhr-17 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
5	rgs-1	C05B5.7	n/a	chrIII 10,015,270	rgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons.
6	F36D4.4	F36D4.4	n/a	chrV 9,404,118	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000832 (GPCR, family 2, secretin-like), IPR000276 (GPCR, rhodopsin-like)
7	F40G9.8	F40G9.8	n/a	chrIII 164,235
8	K12H6.10	K12H6.10	n/a	chrII 2,822,965
9	str-3	M7.13	n/a	chrIV 11,099,437	str-3 encodes a seven transmembrane chemosensory receptor; STR-3 is expressed in the ASI chemosensory neurons; STR-3 expression in ASI is repressed in the presence of dauer pheromone at concentrations lower than that which induces dauer formation.
10	nas-28	F42A10.8	n/a	chrIII 6,182,093	C. elegans NAS-28 protein; contains similarity to Pfam domain PF01400 Astacin (Peptidase family M12A) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
11	paf-1	W03G9.6	n/a	chrI 4,985,729	paf-1 encodes one of two C. elegans homologs of mammalian Type II platelet-activating factor-acetylhydrolase (PAF-AH).
12	F53B1.3	F53B1.3	n/a	chrX 2,106,394
13	zig-4	C09C7.1	n/a	chrX 7,925,923	zig-4 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; ZIG-4 activity is required for maintenance of ventral nerve cord organization: the AVKL/R and PVQL/R axons of the left and right ventral nerve cords do not maintain their proper spatial positions and drift into the opposite cord; a zig-4::gfp reporter fusion is expressed in the PVT, ASK, BAG, and M2 neurons, with expression also seen during the L1 stage in pharyngeal mesoderm and ectoderm.
14	srj-13	R13D7.3	n/a	chrV 7,403,263	C. elegans SRJ-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	adt-1	C02B4.1	n/a	chrX 12,683,974	The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis.
16	F41E7.7	F41E7.7	n/a	chrX 10,311,728	contains similarity to Drosophila grimshawi Chorion protein S18.; SW:CH18_DROGR
17	F54B8.4	F54B8.4	n/a	chrV 15,816,808	The F54B8.4 gene encodes a homolog of Death Associated Protein 1 (DAP-1) protein that may be involved in apoptosis.
18	T09E8.4	T09E8.4	n/a	chrV 13,182,889	contains similarity to Pfam domain PF02460 Patched family contains similarity to Interpro domains IPR003392 (Patched), IPR000731 (Sterol-sensing 5TM box)
19	fbxa-73	T20H9.4	n/a	chrIII 2,254,103	C. elegans FBXA-73 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
20	F10F2.4	F10F2.4	n/a	chrIII 4,624,572	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
21	F14D7.5	F14D7.5	n/a	chrV 14,299,389	contains similarity to Bacteroides thetaiotaomicron Hypothetical protein.; TR:Q8ABS0
22	K03B4.4	K03B4.4	n/a	chrV 4,684,430	contains similarity to Interpro domain IPR002411 (Cereal allergen/alpha-amylase inhibitor, rice-type)
23	R03H10.5	R03H10.5	n/a	chrII 4,170,159	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
24	F11G11.4	F11G11.4	n/a	chrII 4,861,326
25	odr-3	C34D1.3	n/a	chrV 13,248,189	odr-3 encodes a G protein alpha subunit; odr-3 activity is required for normal chemotaxis, odorant avoidance, and nociceptive function as well as cilium morphogenesis in chemosensory neurons; an ODR-3::GFP is expressed in five pairs of sensory neurons AWA, AWB, AWC, ASH, and ADF; the AWC neurons consistently express GFP most strongly, while the AWB neurons express at lower levels and the AWA, ASH, and ADF neurons express only weakly; in AWC neurons, ODR-3::GFP localizes to cilia which have a characteristic wing-shaped morphology.
26	C13A10.2	C13A10.2	n/a	chrII 1,357,598
27	B0524.5	B0524.5	n/a	chrIII 1,892,549	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
28	D2062.1	D2062.1	n/a	chrII 2,632,264	contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
29	str-115	F07B10.3	n/a	chrV 11,269,735	C. elegans STR-115 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	C15B12.3	C15B12.3	n/a	chrX 6,467,380
31	clec-211	F19F10.6	n/a	chrV 7,560,915	C. elegans CLEC-211 protein; contains similarity to Interpro domain IPR016187 (C-type lectin fold)
32	C50E3.8	C50E3.8	n/a	chrV 7,598,180
33	srg-40	T19C4.4	n/a	chrV 11,163,867	C. elegans SRG-40 protein; contains similarity to Interpro domains IPR000500 (Connexins), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
34	M01E10.3	M01E10.3	n/a	chrIII 2,054,148	contains similarity to Interpro domain IPR016187 (C-type lectin fold)
35	R102.3	R102.3	n/a	chrIV 10,691,049	contains similarity to Broad bean wilt virus 2 210kDa protein.; TR:Q9E933
36	unc-46	C04F5.3	n/a	chrV 5,098,120	unc-46 encodes a novel protein with a single predicted transmembrane domain; UNC-46 and UNC-47, a novel transmembrane vesicular GABA transporter, are required in GABAergic neurons for all GABA neurotransmission, specifically for loading of GABA into synaptic vesicles, where UNC-46 is localized; UNC-46 localization requires UNC-47, which when overexpressed can rescue unc-46 mutant animals.
37	C17A2.4	C17A2.4	n/a	chrII 3,840,560	contains similarity to Cebus apella Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (GDP-L-sfucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)s(Alpha(1,2)FT 1) (Fucosyltransferase 1).; SW:Q866E8
38	C02B8.7	C02B8.7	n/a	chrX 8,137,743
39	F11A5.13	F11A5.13	n/a	chrV 16,226,353	contains similarity to Clostridium acetobutylicum MDR-type permease.; TR:Q97D15
40	sue-1	F07A5.5	n/a	chrI 7,365,960	C. elegans SUE-1 protein; contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR013032 (EGF-like region, conserved site)
41	ZC239.3	ZC239.3	n/a	chrII 3,216,335	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
42	F22F7.3	F22F7.3	n/a	chrV 2,113,100	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
43	glc-3	ZC317.3	n/a	chrV 5,451,485	The glc-3 gene encodes a fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit.
44	npr-3	C10C6.2	n/a	chrIV 11,461,555	C10C6.2 encodes a G-protein-coupled receptor for the FMRFamide-related peptides (FaRPs) encoded by flp-15; C10C6.2 is primarily coupled to Gi/Go proteins, since C10C6.2 signalling is blocked by pertussis toxin; because of its link to Gi/Go proteins, C10C6.2 is expected to be inhibitory
45	ugt-36	F09G2.6	n/a	chrV 7,168,088	C. elegans UGT-36 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR008081 (Cytoplasmic FMR1-interacting), IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
46	acr-15	F25G6.4	n/a	chrV 8,554,009	A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
47	Y60C6A.1	Y60C6A.1	n/a	chrV 4,784,867	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
48	ZC412.1	ZC412.1	n/a	chrV 14,855,683	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
49	F10E7.1	F10E7.1	n/a	chrII 7,127,780	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
50	ins-3	ZK75.3	n/a	chrII 5,990,388	ins-3 encodes one of several insulin-related peptides; INS-3 is classified as a Type-beta insulin based on the predicted arrangement of disulfide bonds; gfp gene fusions with the promoter and enhancer regions indicate that INS-3 is expressed in some amphid sensory neurons.