UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C30H6.9	C30H6.9	8.000000000000001e-113	chrIV 17,379,717	contains similarity to Bacillus anthracis Hypothetical protein.; TR:Q81PV8
2	aqp-7	M02F4.8	n/a	chrX 3,026,113	aqp-7 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases either water or glycerol permeability five- to seven-fold; AQP-7 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its several paralogs; AQP-7 is expressed in muscle punctae (perhaps focal adhesions).
3	nhr-33	ZK455.6	n/a	chrX 11,319,573	C. elegans NHR-33 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	F28A10.5	F28A10.5	n/a	chrII 850,172	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
5	ces-1	F43G9.11	n/a	chrI 8,634,989	ces-1 encodes a C2H2-type zinc finger transcription factor that is a member of the Snail family of proteins that includes Drosophila Scratch, Snail, and Slug, and human SNAIL and SLUG; although the normal function of CES-1 is not fully understood, gain-of-function mutations indicate that CES-1 can function as a transcriptional repressor that blocks programmed cell death in specific neurons by inhibiting expression of the cell-death activator EGL-1; in regulating EGL-1 expression, CES-1 appears to antagonize the transcriptional activity of the bHLH proteins, HLH-2 and HLH-3; despite its cell-type specific role in apoptosis, CES-1 expression is reportedly detected in many embryonic nuclei from the 100-cell stage of embryogenesis through the beginning of morphogenesis, with some CES-1 expression remaining at later embryonic stages; genetic studies indicate that CES-1 is negatively regulated by the bZIP transcription factor CES-2, which can bind CES-1 upstream sequences in vitro and thus may directly regulate CES-1 transcription in vivo
6	F11D11.4	F11D11.4	n/a	chrV 18,762,417	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
7	ZK380.4	ZK380.4	n/a	chrX 1,652,654
8	srj-40	F38H12.2	n/a	chrV 4,102,865	C. elegans SRJ-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	taf-9	T12D8.7	n/a	chrIII 13,624,992	C. elegans TAF-9 protein; contains similarity to Pfam domain PF02291 Transcription initiation factor IID, 31kD subunit contains similarity to Interpro domains IPR003162 (Transcription factor TAFII-31), IPR009072 (Histone-fold)
10	srj-7	T28A11.10	n/a	chrV 3,245,861	C. elegans SRJ-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	F59B2.13	F59B2.13	n/a	chrIII 9,025,413	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
12	C28A5.5	C28A5.5	n/a	chrIII 4,451,510	contains similarity to Petunia hybrida PGPS/D8.; TR:Q9ZTN1
13	fbxa-100	F14H3.7	n/a	chrV 16,060,910	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
14	F55E10.1	F55E10.1	n/a	chrX 8,342,071
15	F36A4.11	F36A4.11	n/a	chrIV 4,245,281
16	srx-135	F09F3.11	n/a	chrV 13,860,290	C. elegans SRX-135 protein ;
17	K10D2.4	K10D2.4	n/a	chrIII 5,173,569
18	ceh-14	F46C8.5	n/a	chrX 7,530,621	ceh-14 encodes a LIM homeodomain protein orthologous to Drosophila Lim3 and the vertebrate Lhx3 and Lhx4 proteins; ceh-14 is required for specification of the AFD thermosensory neurons and for normal thermotactic behavior; a ceh-14::GFP reporter fusion is expressed in head and tail neurons, including the AFD thermosensory neurons, during late embryonic, larval, and adult stages. Animals triply mutant for the LIM homeobox genes ceh-14, lin-11, and ttx-3 which are required for function of the AFD, AIZ, and AIY neurons, respectively, exhibit a basic cryophilic thermotaxis response suggesting that, in C. elegans, there is more than one pathway for integration of thermosensory input.
19	srh-281	F11A5.1	n/a	chrV 16,191,496	C. elegans SRH-281 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
20	puf-4	M4.2	n/a	chrIV 3,207,566	C. elegans PUF-4 protein; contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
21	H08J19.1	H08J19.1	n/a	chrX 15,643,559	contains similarity to Homo sapiens formin-like 3 isoform 1; ENSEMBL:ENSP00000335655
22	M03F8.5	M03F8.5	n/a	chrV 5,935,209	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domain IPR004245 (Protein of unknown function DUF229)
23	K04E7.1	K04E7.1	n/a	chrX 6,462,585
24	C10E2.5	C10E2.5	n/a	chrX 16,752,685
25	F26F2.3	F26F2.3	n/a	chrV 20,561,363	contains similarity to Saccharomyces cerevisiae Profilin synthetic lethal protein, has region of coiled-coil structure; subunit of the Exocyst complex--the Exocyst complex contains the gene products encoded by SEC3, SEC5, SEC6, SEC8, SEC10, SEC15 and EXO70 and is required for exocytosis; SGD:YER008C
26	unc-40	T19B4.7	n/a	chrI 5,685,676	The unc-40 gene encodes a netrin receptor that is required to guide dorsal-ventral cell and axon migrations, and is required for correct polarization and migration of the neuroblasts QL and QR.
27	srd-21	W06G6.3	n/a	chrV 16,630,499	C. elegans SRD-21 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	srv-9	F53F1.8	n/a	chrV 13,422,059	C. elegans SRV-9 protein ;
29	T11F9.13	T11F9.13	n/a	chrV 11,482,664	contains similarity to Thermotoga maritima ATP-dependent CLP protease, ATPase subunit.; TR:Q9WY41
30	math-9	C16C4.14	n/a	chrII 1,890,347	C. elegans MATH-9 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
31	str-198	ZK285.1	n/a	chrV 16,048,450	C. elegans STR-198 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	R160.2	R160.2	n/a	chrX 4,376,697
33	C27D6.1	C27D6.1	n/a	chrII 5,174,657	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
34	fip-5	F41E7.4	n/a	chrX 10,302,828	C. elegans FIP-5 protein; contains similarity to Interpro domain IPR000480 (Glutelin)
35	tag-83	F46F11.3	n/a	chrI 5,602,718	C. elegans TAG-83 protein ; contains similarity to Homo sapiens TNS1 protein; ENSEMBL:ENSP00000308321
36	B0348.1	B0348.1	n/a	chrV 49,270	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
37	R05A10.5	R05A10.5	n/a	chrIV 14,169,839	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
38	pop-1	W10C8.2	n/a	chrI 2,826,881	pop-1 encodes an HMG box-containing protein that is the sole C. elegans member of the TCF/LEF family of transcription factors; in C. elegans, POP-1 functions as a component of the canonical and noncanonical Wnt signaling pathways that are required for cell migrations and binary cell fate decisions associated with asymmetric cell division, respectively; in yeast two-hybrid assays, the POP-1 N-terminal beta-catenin binding domain interacts with BAR-1/beta-catenin as well as with the more divergent beta-catenin, SYS-1; when coexpressed with SYS-1, POP-1 is able to activate transcription from a promoter with TCF binding sites; during development, maternally provided POP-1 is first detected in the nuclei of maturing oocytes and then in nearly all cells of the early embryo; in sister blastomeres in the early embryo, POP-1 is detected at lower levels in posterior blastomeres, such as E and P3, than in corresponding anterior blastomeres, MS and C; in later developmental stages, POP-1 is detected in a subset of tissues including hypodermal seam cells, gonadal precursors, and the developing vulva; in the vulva, POP-1 also exhibits an asymmetric staining pattern, with sister cells showing high or low levels of POP-1 depending upon their orientation along the anterior/posterior axis of the vulva.
39	K03D7.9	K03D7.9	n/a	chrV 17,488,056	contains similarity to Homo sapiens Olfactory receptor 1A1; ENSEMBL:ENSP00000305207
40	F56H6.3	F56H6.3	n/a	chrI 12,289,861
41	R05D7.1	R05D7.1	n/a	chrI 12,162,955	contains similarity to Kluyveromyces lodderae Truncated cytochrome oxidase subunit 2 (Fragment).; TR:Q7YG01
42	F56H6.2	F56H6.2	n/a	chrI 12,288,243	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
43	clec-168	F38A1.7	n/a	chrIV 1,258,213	C. elegans CLEC-168 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
44	K09B11.4	K09B11.4	n/a	chrIV 13,429,722	contains similarity to Patella vulgata Twist protein (Fragment).; TR:Q8WQQ8
45	K07D4.2	K07D4.2	n/a	chrII 4,045,127
46	sra-7	AH6.11	n/a	chrII 9,545,368	C. elegans SRA-7 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
47	C27F2.5	C27F2.5	n/a	chrIII 4,961,124	C27F2.5 encodes the C. elegans ortholog of the conserved vacuolar protein sorting protein EAP30/SNF8/VPS22; by homology, the product of C27F2.5 is predicted to be a component of an ESCRT-II complex (Endosomal Sorting Complex Required for Transport) that functions in endosomal transport.
48	K04A8.2	K04A8.2	n/a	chrV 6,563,097	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
49	R07E5.15	R07E5.15	n/a	chrIII 4,401,952
50	F45F2.7	F45F2.7	n/a	chrV 8,523,135	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR004878 (Protein of unknown function DUF270), IPR016196 (MFS general substrate transporter)