UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C30F12.7	C30F12.7	0	chrI 6,975,813	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004434 (Isocitrate dehydrogenase NAD-dependent, mitochondrial), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
2	lec-4	C44F1.3	n/a	chrIII 3,772,356	lec-4 encodes a predicted galectin that exhibits sugar binding properties in vitro.
3	F56B3.6	F56B3.6	n/a	chrIV 789,430	contains similarity to Pfam domain PF03134 TB2/DP1, HVA22 family contains similarity to Interpro domain IPR004345 (TB2/DP1 and HVA22 related protein)
4	C18E9.9	C18E9.9	n/a	chrII 8,988,878	contains similarity to Thermoplasma volcanium Hypothetical protein TV1312.; TR:Q978V3
5	F42C5.4	F42C5.4	n/a	chrIV 7,290,079	contains similarity to Interpro domain IPR001841 (Zinc finger, RING-type)
6	F43G9.3	F43G9.3	n/a	chrI 8,613,923	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002167 (Graves disease carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
7	far-8	K02F3.3	n/a	chrIII 843,359	C. elegans FAR-8 protein ;
8	R02D5.3	R02D5.3	n/a	chrV 14,483,717	contains similarity to Arabidopsis thaliana Putative RNA-binding protein.; TR:Q9SHZ5
9	Y11D7A.14	Y11D7A.14	n/a	chrIV 9,278,808	Y11D7A.14 encodes a putative myosin, with an N-terminal myosin head motor domain and a C-terminal coiled-coil domain; Y11D7A.14 has no obvious function in mass RNAi assays.
10	F13H8.8	F13H8.8	n/a	chrII 6,266,588	contains similarity to Drosophila hydei Axoneme-associated protein mst101(2).; SW:Q08696
11	ttr-46	T07C12.7	n/a	chrV 9,951,666	C. elegans TTR-46 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
12	F47D12.3	F47D12.3	n/a	chrIII 6,298,853	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
13	Y17G7B.8	Y17G7B.8	n/a	chrII 12,026,748	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
14	F42G2.2	F42G2.2	n/a	chrII 2,423,776	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
15	W07B8.3	W07B8.3	n/a	chrV 1,125,705
16	F57G4.5	F57G4.5	n/a	chrV 17,642,359	contains similarity to Mus musculus Dentin sialophosphoprotein precursor (Dentin matrix protein-3) (DMP-s3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP);sDentin sialoprotein (DSP)].; SW:DSPP_MOUSE
17	K03H1.10	K03H1.10	n/a	chrIII 9,923,743	contains similarity to Pfam domains PF02172 (KIX domain) , PF02135 (TAZ zinc finger) contains similarity to Interpro domains IPR003101 (Coactivator CBP, KIX), IPR000197 (Zinc finger, TAZ-type)
18	K03H1.5	K03H1.5	n/a	chrIII 9,935,960	contains similarity to Pfam domains PF03782 (AMOP domain) , PF06119 (Nidogen-like) , PF00094 (von Willebrand factor type D domain) , PF00084 (Sushi domain (SCR repeat)) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR005533 (AMOP), IPR002909 (Cell surface receptor IPT/TIG), IPR000436 (Sushi/SCR/CCP), IPR000694 (Proline-rich region), IPR003886 (Nidogen, extracellular region), IPR016060 (Complement control module), IPR001846 (von Willebrand factor, type D)
19	C01H6.6	C01H6.6	n/a	chrI 7,223,298	C01H6.6 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C33D12.2, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C01H6.6 may participate in metal homoeostasis; C01H6.6, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C01H6.6 has no obvious function in RNAi assays.
20	grd-14	T01B10.2	n/a	chrX 8,500,290	grd-14 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-14 is required for normal growth to full size, locomotion, and vulval morphogenesis; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
21	C14C6.2	C14C6.2	n/a	chrV 563,724	contains similarity to Pfam domains PF04942 (CC domain) , PF01549 (ShK domain-like) (2)contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR003582 (Metridin-like ShK toxin)
22	plc-2	Y75B12B.6	n/a	chrV 15,195,140	C. elegans PLC-2 protein; contains similarity to Pfam domains PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes)
23	csp-3	Y47H9C.6	n/a	chrI 11,888,911	csp-3 encodes a protein that is homologous to the C-terminal domain of caspase-like cysteine proteases; unlike other caspases, CSP-3 does not contain a middle or N-terminal domain, and thus may either function in concert with the middle domains of other caspases or may play a regulatory (dominant negative) role in caspase activation; as loss of csp-3 activity via large-scale RNAi does not result in any obvious abnormalities, the precise role of CSP-3 in C. elegans development and/or behavior is not yet known.
24	gsnl-1	K06A4.3	n/a	chrV 9,498,184	C. elegans GSNL-1 protein; contains similarity to Pfam domain PF00626 Gelsolin repeat contains similarity to Interpro domains IPR007122 (Gelsolin), IPR007123 (Gelsolin region)
25	Y49E10.16	Y49E10.16	n/a	chrIII 12,432,047	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)
26	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
27	ZC247.2	ZC247.2	n/a	chrI 10,258,909	contains similarity to Homo sapiens similar to KIAA1203 protein; ENSEMBL:ENSP00000219689
28	F22B3.8	F22B3.8	n/a	chrIV 11,423,572	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
29	Y11D7A.1	Y11D7A.1	n/a	chrIV 9,229,724	contains similarity to Interpro domains IPR003702 (Acetyl-CoA hydrolase/transferase), IPR001220 (Legume lectin, beta domain)
30	aman-3	F48C1.1	n/a	chrI 5,327,364	aman-3 encodes a Co(II)-activated alpha-mannosidase II, orthologous to human MAN2C1; AMAN-3 is predicted to remove mannose residues from the N-linked oligosaccharides of glycoproteins; AMAN-3 contains three predicted N-glycosylation sites; AMAN-3 is biochemically active in vitro, with a pH optimum of 6.5; AMAN-3 requires either Co(II) or Mn(II) for activity, preferring the former ion; since aman-2(tm1078) mutants almost completely lack paucimannosidic glycans, the function of AMAN-3 in vivo is unclear.
31	grl-9	ZC487.4	n/a	chrV 6,730,970	grl-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
32	dhs-30	T25G12.7	n/a	chrX 17,233,193	dhs-30 encodes a member of the short-chain dehydrogenases/reductases family (SDR) homologous to HSD, which when mutated leads to cortisol 11-beta ketoreductase deficiency (OMIM:218030).
33	tyr-4	C34G6.2	n/a	chrI 5,900,210	C. elegans TYR-4 protein; contains similarity to Pfam domains PF00264 (Common central domain of tyrosinase) , PF01549 (ShK domain-like) (4)contains similarity to Interpro domains IPR000817 (Prion protein), IPR008922 (Di-copper centre-containing), IPR002227 (Tyrosinase), IPR003582 (Metridin-like ShK toxin)
34	F35C8.2	F35C8.2	n/a	chrX 5,375,578	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
35	ttr-12	F46B3.4	n/a	chrV 20,603,550	C. elegans TTR-12 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
36	F09B9.1	F09B9.1	n/a	chrX 10,140,628	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
37	srr-9	T05B11.2	n/a	chrV 7,738,784	C. elegans SRR-9 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
38	C49C8.1	C49C8.1	n/a	chrIV 8,655,687	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
39	T10E9.3	T10E9.3	n/a	chrI 6,536,631	contains similarity to Pfam domain PF03351 DOMON domain contains similarity to Interpro domains IPR005018 (DOMON related), IPR013050 (DOMON)
40	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	F54C9.3	F54C9.3	n/a	chrII 8,566,635	contains similarity to Homo sapiens BA424I5.1; TR:Q9H4Q7
42	Y41E3.6	Y41E3.6	n/a	chrIV 15,006,683	contains similarity to Bacillus halodurans Stress-and starvation-induced gene controlled by sigma-B.; TR:Q9KE40
43	ncr-1	F02E8.6	n/a	chrX 4,476,155	ncr-1 encodes a large transmembrane glycoprotein with a patched-like domain that is orthologous to human NPC1 (OMIM:257220, mutated in Niemann-Pick type C disease); NCR-1 and NPC1 are eukaryotic members of the resistance-nodulation-division (RND) family of membrane permeases, and have a putative sterol-sensing domain; by homology, NCR-1 is predicted to function in intracellular cholesterol and glycolipid trafficking; in C. elegans, NCR-1 is required for growth and survival in the absence of cholesterol, newly hatched ncr-1 mutant larvae grow poorly on cholesterol-free medium and die at the L1 or L2 stage; NCR-1 is also involved in negative regulation of dauer formation, being required redundantly with NCR-2, a second C. elegans NPC1-like protein, for preventing constitutive dauer formation; dauer formation in ncr-1; ncr-2 double mutants is suppressed by mutations in daf-12, which encodes a steroid hormone receptor, and by overexpression of daf-9, which encodes a cytochrome P450, suggesting that NCR-1 and NCR-2 may function to transport a sterol precursor that is metabolized by DAF-9 to then serve as the DAF-12 ligand.
44	F36D3.5	F36D3.5	n/a	chrV 16,512,428	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
45	F58H7.8	F58H7.8	n/a	chrIV 908,458
46	apm-1	F55A12.7	n/a	chrI 5,343,455	The apm-1 gene encodes an adaptin: specifically, it encodes an ortholog of the mu1-II subunit of adaptor protein complex 1 (AP-1).
47	pat-10	F54C1.7	n/a	chrI 5,019,533	pat-10 encodes body wall muscle troponin C, the calcium-binding component of the troponin complex of actin thin filaments; PAT-10 is essential for muscle contraction and thus for completion of embryonic morphogenesis and elongation; by homology, PAT-10 likely functions to regulate body wall muscle contraction in response to changes in intracellular calcium; PAT-10 is expressed in body wall muscle but is also detected in vulval and anal muscles; expression in body wall muscle begins during early embryonic morphogenesis, concurrent with expression of other body wall muscle structural components.
48	hmit-1.2	Y51A2D.5	n/a	chrV 18,526,923	hmit-1.2 encodes one of three C. elegans proton (H+)-dependent myo-inositol transporters; loss of hmit-1.2 activity via large-scale RNAi result in no obvious abnormalities but by homology, HMIT-1.2 is predicted to function as a plasma membrane protein required for the regulated uptake of myo-inositol and thus potentially for regulation of cell signaling and intracellular osmolarity.
49	C05C12.4	C05C12.4	n/a	chrIV 11,247,231	contains similarity to Interpro domains IPR002049 (EGF-like, laminin), IPR013032 (EGF-like region, conserved site)
50	C34C12.4	C34C12.4	n/a	chrIII 3,468,832	contains similarity to Homo sapiens Uncharacterized protein C4orf34; ENSEMBL:ENSP00000295958