UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C30B5.4	C30B5.4	5e-145	chrII 6,196,350	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
2	C23H3.5	C23H3.5	n/a	chrII 48,839
3	F54B8.1	F54B8.1	n/a	chrV 15,811,031	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
4	W05G11.2	W05G11.2	n/a	chrIII 58,191	contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal)
5	F31E3.4	F31E3.4	n/a	chrIII 6,965,804	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR011046 (WD40 repeat-like), IPR006055 (Exonuclease), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
6	T28D6.6	T28D6.6	n/a	chrIII 11,334,762	contains similarity to Pfam domains PF01926 (GTPase of unknown function) , PF02824 (TGS domain) contains similarity to Interpro domains IPR005225 (Small GTP-binding protein), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG), IPR004095 (TGS), IPR006074 (GTP1/OBG, conserved site)
7	T08A11.1	T08A11.1	n/a	chrIII 4,255,571	contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region), IPR000591 (Pleckstrin/ G-protein, interacting region)
8	cir-1	F55F8.4	n/a	chrI 5,654,871	C. elegans CIR-1 protein ; contains similarity to Homo sapiens Isoform 1 of CBF1-interacting corepressor; ENSEMBL:ENSP00000339723
9	eri-3	W09B6.3	n/a	chrII 1,125,668	C. elegans ERI-3 protein ;
10	W04B5.1	W04B5.1	n/a	chrIII 2,428,781
11	F32B6.3	F32B6.3	n/a	chrIV 9,883,182	contains similarity to Pfam domains PF02840 (Prp18 domain) , PF08799 (pre-mRNA processing factor 4 (PRP4) like) contains similarity to Interpro domains IPR014906 (Pre-mRNA processing factor 4 (PRP4) like), IPR003648 (Splicing factor motif), IPR004098 (Prp18)
12	T24A6.17	T24A6.17	n/a	chrV 3,564,846
13	C08B6.8	C08B6.8	n/a	chrV 10,138,746	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
14	Y40B1B.8	Y40B1B.8	n/a	chrI 13,431,748	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domain IPR001993 (Mitochondrial substrate carrier)
15	cid-1	K10D2.3	n/a	chrIII 5,177,184	cid-1 (also known as pup-1) encodes a template-independent poly(U) polymerase with 3'' end RNA substrates, orthologous to human ZCCHC6 and ZCCHC11, and paralogous to PUP-2; CID-1 prevents larvae from growing to adulthood in media containing hydroxyurea (HU, a drug that stalls replication forks) and represses HSP-4 expression; CID-1 is required for gonadogenesis, embryonic and vulval development, normally rapid growth, and normally short lifespan; CID-1, like HSP-4, is expressed in postmitotic intestinal cells; by orthology with Cid1p in fission yeast, CID-1 is predicted to act in a DNA synthesis-to-mitosis checkpoint; in cid-1(rf35::Tc4) mutants or cid-1(RNAi) animals grow from L1 larvae to adulthood despite the presence of HU, are abnormally resistant to lethal heat shock, overexpress hsp-4::GFP, have protruding vulvae, have abnormally short and thick gonads with fewer germ cells than normal, produce disorganized embryos, grow slowly, and have abnormally long lifespans; CID-1 and its eukaryotic homologs are distantly related to the GLD-2 family of poly(A) polymerases.
16	W02B12.10	W02B12.10	n/a	chrII 11,472,796	contains similarity to Pfam domain PF02390 Putative methyltransferase contains similarity to Interpro domains IPR004395 (Conserved hypothetical protein CHP00091), IPR003358 (Putative methyltransferase)
17	C24G6.3	C24G6.3	n/a	chrV 5,517,383	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
18	T12G3.5	T12G3.5	n/a	chrIV 12,031,705	contains similarity to Drosophila melanogaster Flybase gene name is mRpL51-PA;; FLYBASE:CG13098
19	T02C12.3	T02C12.3	n/a	chrIII 4,023,867	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q16W48
20	gip-2	C45G3.3	n/a	chrI 9,227,490	gip-2 encodes a member of the Biotin/lipoate A/B protein ligase family.
21	cya-2	F59H6.7	n/a	chrII 2,023,091	C. elegans CYA-2 protein; contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal)
22	npp-2	T01G9.4	n/a	chrI 8,292,456	npp-2 encodes a protein with low similarity to rat nucleoporin Nup75 that affects embryonic viability and has a variety of other defects in RNAi screens including: nuclear morphology, growth, fertility, locomotion, and egg laying; enriched in oocytes.
23	C25A11.2	C25A11.2	n/a	chrX 9,115,559	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
24	nas-27	T23F4.4	n/a	chrII 1,177,703	nas-27 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-27::GFP promoter fusion is expressed in the reproductive system, the vulva, and the hypodermis.
25	K10E9.1	K10E9.1	n/a	chrI 196,071
26	mix-1	M106.1	n/a	chrII 10,832,781	The mix-1 gene encodes a homolog of SMC2 involved in chromosome segregation, X-chromosome gene regulation, and repression of X-linked genes during dosage compensation.
27	C14B1.8	C14B1.8	n/a	chrIII 3,719,182	C14B1.8 encodes a coiled-coil protein.
28	ZK795.3	ZK795.3	n/a	chrIV 12,559,996	contains similarity to Pfam domain PF04427 Brix domain contains similarity to Interpro domain IPR007109 (Brix)
29	K02E7.2	K02E7.2	n/a	chrII 1,080,452
30	C06H2.3	C06H2.3	n/a	chrV 11,128,767	contains similarity to Pfam domains PF02373 (JmjC domain) , PF00583 (Acetyltransferase (GNAT) family) contains similarity to Interpro domains IPR013129 (Transcription factor jumonji), IPR003347 (Transcription factor jumonji/aspartyl beta-hydroxylase), IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase)
31	K07C5.3	K07C5.3	n/a	chrV 10,344,230	contains similarity to Pfam domain PF00645 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region contains similarity to Interpro domain IPR001510 (Zinc finger, PARP-type)
32	K10B2.4	K10B2.4	n/a	chrII 6,360,595	contains similarity to Pfam domain PF03669 Uncharacterised protein family (UPF0139) contains similarity to Interpro domain IPR005351 (Protein of unknown function UPF0139)
33	npp-11	F53F10.5	n/a	chrI 3,819,703	C. elegans NPP-11 protein; contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000104 (Antifreeze protein, type I), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR007758 (Nucleoporin, Nsp1-like, C-terminal)
34	F23C8.9	F23C8.9	n/a	chrI 2,433,103	contains similarity to Pfam domain PF07962 Replication Fork Protection Component Swi3 contains similarity to Interpro domain IPR012923 (Replication fork protection component Swi3)
35	F17A9.2	F17A9.2	n/a	chrV 6,111,285	contains similarity to Pfam domains PF04676 (Protein similar to CwfJ C-terminus 2) , PF04677 (Protein similar to CwfJ C-terminus 1) contains similarity to Interpro domains IPR006768 (Protein similar to CwfJ, C-terminal 1), IPR006767 (Protein similar to CwfJ, C-terminal 2), IPR011146 (Histidine triad-like motif)
36	Y54G11A.2	Y54G11A.2	n/a	chrII 14,253,902	contains similarity to Pfam domain PF05670 Domain of unknown function (DUF814) contains similarity to Interpro domain IPR008532 (Protein of unknown function DUF814)
37	ergo-1	R09A1.1	n/a	chrV 1,013,580	C. elegans ERGO-1 protein; contains similarity to Pfam domains PF02170 (PAZ domain) , PF02171 (Piwi domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
38	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
39	tag-203	K02F2.3	n/a	chrI 6,824,603	C. elegans TAG-203 protein; contains similarity to Pfam domain PF03178 CPSF A subunit region contains similarity to Interpro domains IPR004871 (Cleavage and polyadenylation specificity factor, A subunit, C-terminal), IPR011046 (WD40 repeat-like), IPR015943 (WD40/YVTN repeat-like)
40	sna-1	W02F12.6	n/a	chrV 6,710,071	sna-1 encodes an snRNP-binding protein (SNA-1/SL21p) orthologous to Ascaris SL30p (SL 30kd) and Brugia 13258.m00169, and paralogous to Brugia 14704.m00455; SNA-1 is found in the Sm snRNP SL1, but not in SL2; in snRNP SL1, SNA-1 associates with the SNA-2/SL75p protein, while being replaced by SUT-1/SL26p (a paralog of SNA-1) in snRNP Y; sna-1(RNAi) animals, like sut-1(bk79) mutants, have cold-sensitive sterility, whereas sna-1(RNAi) combined with sut-1(bk79) is synthetically lethal; double sna-1(RNAi) sut-1(RNAi) is lethal; these RNAi data indicate that SNA-1 and SUT-1 are partially redundant, and suggest that snRNP Y (like snRNP SL1) may participate in trans-splicing; SNA-1 can bind SNA-2 even in the absence of RNA.
41	cua-1	Y76A2A.2	n/a	chrIII 13,447,397	The cua-1 gene encodes a putative E1-E2 ATPase orthologous to the human gene KIAA1347 (ATP7A; OMIM:604384), which when mutated leads to Hailey-Hailey disease.
42	lpd-2	C48E7.3	n/a	chrI 6,254,291	C. elegans LPD-2 protein; contains similarity to Interpro domain IPR010916 (TonB box, conserved site)
43	F55A3.2	F55A3.2	n/a	chrI 10,795,710	contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR015880 (Zinc finger, C2H2-like)
44	F55G1.9	F55G1.9	n/a	chrIV 7,476,741	contains similarity to Pfam domain PF03807 NADP oxidoreductase coenzyme F420-dependent contains similarity to Interpro domains IPR004455 (NADP oxidoreductase, coenzyme F420-dependent), IPR000304 (Delta 1-pyrroline-5-carboxylate reductase), IPR016040 (NAD(P)-binding)
45	C04C3.4	C04C3.4	n/a	chrIV 3,394,502
46	C45G9.5	C45G9.5	n/a	chrIII 5,049,097
47	ZK1098.2	ZK1098.2	n/a	chrIII 9,530,428	contains similarity to Klebsiella aerogenes Siroheme synthetase.; TR:Q9EYX8
48	dyrb-1	T24H10.6	n/a	chrII 9,106,748	dyrb-1 encodes a small (95-residue) putative cytoplasmic dynein light chain 2A that inhibits DHC-1 in vivo, and is also required for mitotic spindle positioning, embryonic viability and fertility; DYRB-1 is orthologous to Drosophila ROADBLOCK (and six Drosophila paralogs), Chlamydomonas LC7, human DYNLRB1 (OMIM:607167), and human DYNLRB2 (OMIM:607168); dyrb-1(RNAi) and dyrb-1(tm2645) both suppress the lethality of conditional dhc-1 mutations, and dyrb-1(RNAi) suppresses dhc-1(or195) spindle length and cytokinesis defects as well, indicating that DYRB-1 negatively regulates dynein; in oocytes and early embryos, DYRB-1 is associated with nuclear envelopes and centrosomes, and with meiotic and mitotic spindle poles; like DHC-1 itself, DYRB-1 is strongly mislocalized to centrosomes in dhc-1(or195) animals shifted to nonpermissive temperature.
49	sec-3	F52E4.7	n/a	chrX 3,097,634	C. elegans SEC-3 protein ; contains similarity to Danio rerio Exocyst complex component 1.; TR:Q7T2A6
50	F10G8.6	F10G8.6	n/a	chrI 10,047,224	F10G8.6 encodes an homolog of S. cerevisiae CFD1 (also known as YIL003W/DRE3), a putative P-loop ATPase conserved in eukaryotes and required in yeast for 4Fe-4S cluster assembly; F10G8.6 is also homologous to yeast NBP35/YGL091C; in C. elegans, F10G8.6 is required for normally rapid growth and maintenance of the germline; F10G8.6 protein was predicted to be mitochondrial on the basis of its phylogenetic profile.