UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C29F9.6	C29F9.6	2.0000000000000002e-113	chrIII 115,990	contains similarity to Pfam domain PF02135 TAZ zinc finger contains similarity to Interpro domains IPR003101 (Coactivator CBP, KIX), IPR000197 (Zinc finger, TAZ-type)
2	R02F2.8	R02F2.8	n/a	chrIII 5,494,067	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR013057 (Amino acid transporter, transmembrane)
3	ZK688.2	ZK688.2	n/a	chrIII 7,902,682	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
4	trpa-1	C29E6.2	n/a	chrIV 11,870,347	trpa-1 encodes a transient receptor potential (TRP) ion channel orthologous to the vertebrate and Drosophila TRPA1 channels; in C. elegans, trpa-1 activity is required for specific mechanosensory behaviors such as nose-touch avoidance and touch-mediated foraging; when expressed in mammalian cells, TRPA-1 exhibits channel activity in response to mechanical stimulation; TRPA-1::GFP reporters are expressed in a number of different cell types including sensory neurons, muscle, and epithelial cells.
5	Y54E2A.1	Y54E2A.1	n/a	chrII 14,736,737	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
6	lact-3	M28.6	n/a	chrII 10,654,998	lact-3 encodes a beta-lactamase domain-containing protein that contains a predicted signal sequence; loss of lact-3 activity via RNAi has been reported to result in reduced fat content.
7	orai-1	C09F5.2	n/a	chrIII 653,677	C. elegans ORAI-1 protein; contains similarity to Pfam domain PF07856 Protein of unknown function (DUF1650) contains similarity to Interpro domain IPR012446 (Protein of unknown function DUF1650)
8	sulp-4	K12G11.1	n/a	chrV 11,877,220	sulp-4 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-4 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids and when expressed in Xenopus oocytes, SULP-4 exhibits robust transport of sulfate and more modest transport of chloride ions and oxalate; a SULP-4::GFP fusion is expressed in the apical canaliculae of the excretory cell and also in some head neurons.
9	C28F5.4	C28F5.4	n/a	chrII 7,521,547	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
10	lev-1	F09E8.7	n/a	chrIV 13,176,746	lev-1 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR) which, when mutated, confers resistance to levamisole; LEV-1 is required for completely normal locomotion, and forms a cation channel when coexpressed with UNC-38 or UNC-63 and UNC-29; LEV-1 falls into the 'UNC-29' class of nAChR subunits, which includes UNC-29, ACR-2, and ACR-3.
11	ZC416.1	ZC416.1	n/a	chrIV 3,637,332	n/a
12	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
13	R05A10.3	R05A10.3	n/a	chrIV 14,175,025	contains similarity to Saccharomyces cerevisiae <b><u>C</u></b>onserved <b><u>O</u></b>ligomeric <b><u>G</u></b>olgi complex <b><u>1</u></b><br> Complexed with Cog8p; interacts with Cog2p; SGD:YGL223C
14	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	str-41	R13D7.1	n/a	chrV 7,412,508	C. elegans STR-41 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	T13A10.2	T13A10.2	n/a	chrIV 6,253,526	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
17	K02H8.1	K02H8.1	n/a	chrX 17,004,963	K02H8.1 encodes, by alternative splicing, two isoforms of a putative MUSCLEBLIND-type mRNA splicing regulator required in adults for normal muscle dense body organization, locomotion, and vulval morphogenesis; K02H8.1 is orthologous to Drosophila MBL and human MBNL1 (OMIM:606516), MBNL2 (OMIM:607327), and MBNL3 (OMIM:300413); K02H8.1 is transcribed in larvae and adults; K02H8.1(RNAi) animals show protruding vulvae, progressive uncoordination, and disordered dense bodies; while K02H8.1 is required in adults, it is dispensable in larvae, perhaps reflecting a progressive muscle dystrophy in K02H8.1(RNAi) animals.
18	F17C8.6	F17C8.6	n/a	chrIII 4,745,411	F17C8.6 encodes an alpha1 Ca2+ channel subunit; large-scale RNAi experiments indicate that during development F17C8.6, along with nca-2, may play a role in regulating egg size and shape.
19	clec-192	Y116A8A.1	n/a	chrIV 16,803,039	C. elegans CLEC-192 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
20	K03A11.4	K03A11.4	n/a	chrX 13,080,030	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
21	C50A2.2	C50A2.2	n/a	chrIV 1,173,690	contains similarity to Interpro domains IPR000953 (Chromo domain), IPR016197 (Chromo domain-like)
22	F25E5.2	F25E5.2	n/a	chrV 7,456,619	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
23	nhr-153	C13C4.1	n/a	chrV 12,105,417	C. elegans NHR-153 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core), IPR001781 (Zinc finger, LIM-type)
24	AC8.4	AC8.4	n/a	chrX 227,022
25	C30F2.3	C30F2.3	n/a	chrX 16,084,008	contains similarity to Dictyostelium discoideum Putative uncharacterized protein.; TR:Q1MVQ9
26	E03A3.5	E03A3.5	n/a	chrIII 4,061,679	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold)
27	ubc-23	C28G1.1	n/a	chrX 8,846,276	ubc-23 encodes a predicted conjugating enzyme (UBCs/E2s) of the ubiquitin-conjugation system; expressed in larvae and adults in cells around the pharynx and in intestinal cells.
28	F19B2.6	F19B2.6	n/a	chrV 20,155,401	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23A89
29	srw-7	R08F11.5	n/a	chrV 3,806,992	C. elegans SRW-7 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	F38H4.3	F38H4.3	n/a	chrIV 11,845,293	contains similarity to Interpro domain IPR000694 (Proline-rich region)
31	F59A3.10	F59A3.10	n/a	chrI 5,542,985
32	B0207.11	B0207.11	n/a	chrI 5,963,581	B0207.11 encodes a nematode-specific protein probably required for a normally high ovulation rate; B0207.11 has no obvious non-nematode homologs, but does have a putative N-terminal coiled-coil domain and an SH2 motif, and is is paralogous to four other C. elegans proteins (F42G4.6, F44F4.10, T08G11.2, and Y81G3A.1); B0207.11(tm322) hermaphrodites show abnormal egg-laying, retaining significantly fewer eggs than wild-type (perhaps due to a lowered ovulation rate) while retaining late-stage embryos; B0207.11 has no obvious phenotype in mass RNAi experiments, possibly because of genetic redundancy with its paralogs.
33	C06G3.4	C06G3.4	n/a	chrIV 7,029,714	contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001357 (BRCT)
34	R09H10.1	R09H10.1	n/a	chrIV 10,601,257	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
35	sru-24	F31F4.13	n/a	chrV 669,671	C. elegans SRU-24 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR003839 (Protein of unknown function DUF215), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
36	W02D7.3	W02D7.3	n/a	chrV 8,294,341
37	C53A5.13	C53A5.13	n/a	chrV 14,550,708	contains similarity to Pfam domain PF00041 Fibronectin type III domain contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR003962 (Fibronectin, type III subdomain)
38	nca-2	C27F2.2	n/a	chrIII 4,972,657	nca-2 encodes a novel, four-domain alpha1U Ca2+ channel subunit; nca-2 functions redundantly with a paralog, nca-1, to regulate locomotion and the response to specific volatile anesthetics; in regulating these processes, nca-1 and nca-2 function in the same pathway as unc-79, which encodes a conserved novel protein that positively regulates levels of NCA-1 and NCA-2 protein; nca-2::gfp reporters are expressed in the nervous system in a few pharyngeal neurons, many nerve ring interneurons, most ventral nerve motor cord neurons, and in neurons and muscles in the tail; diffuse expression is also seen in vulval muscles and the intestine.
39	Y43E12A.2	Y43E12A.2	n/a	chrIV 10,983,505	contains similarity to Interpro domain IPR001878 (Zinc finger, CCHC-type)
40	shw-3	R186.5	n/a	chrV 12,974,845	C. elegans SHW-3 protein; contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF07885 (Ion channel) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003973 (Potassium channel, voltage dependent, Kv2), IPR003970 (Potassium channel, voltage dependent, Kv8), IPR003971 (Potassium channel, voltage dependent, Kv9), IPR003968 (Potassium channel, voltage dependent, Kv), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR003969 (Potassium channel, voltage dependent, Kv6), IPR003091 (Voltage-dependent potassium channel), IPR013099 (Ion transport 2), IPR003974 (Potassium channel, voltage dependent, Kv3)
41	Y43F8A.5	Y43F8A.5	n/a	chrV 19,387,467	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
42	srt-8	C50H11.2	n/a	chrV 3,087,272	C. elegans SRT-8 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
43	F49E12.7	F49E12.7	n/a	chrII 8,395,633	contains similarity to Mycobacterium tuberculosis Hypothetical protein (HoxN/HupN/NixA family nickel transporter).; TR:O05804
44	lgc-34	T27A1.4	n/a	chrII 528,462	C. elegans LGC-34 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
45	F37C4.2	F37C4.2	n/a	chrIV 3,887,244	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
46	C18B2.3	C18B2.3	n/a	chrX 3,603,031
47	srw-63	Y37A1B.10	n/a	chrIV 14,014,952	C. elegans SRW-63 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
48	F17H10.1	F17H10.1	n/a	chrX 13,106,728	contains similarity to Danio rerio Protein SERAC1.; SW:Q5SNQ7
49	pho-4	T16D1.2	n/a	chrII 5,237,340	C. elegans PHO-4 protein ;
50	ugt-42	F31F4.7	n/a	chrV 648,465	C. elegans UGT-42 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)