UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C29F7.6	C29F7.6	0	chrX 13,439,091	C29F7.6 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase; C29F7.6 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); C29F7.6 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes; however, C29F7.6 has no obvious function in mass RNAi assays.
2	ZK218.1	ZK218.1	n/a	chrV 17,092,954	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
3	W08F4.10	W08F4.10	n/a	chrII 590,892	contains similarity to Interpro domain IPR000169 (Peptidase, cysteine peptidase active site)
4	T01D3.2	T01D3.2	n/a	chrV 13,706,650	contains similarity to Pfam domain PF00989 PAS fold contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR013767 (PAS fold), IPR000014 (PAS), IPR011598 (Helix-loop-helix DNA-binding), IPR001067 (Nuclear translocator)
5	K10D3.4	K10D3.4	n/a	chrI 7,137,354	contains similarity to Pfam domains PF01683 (EB module) , PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (5)contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat), IPR006149 (Nematode-specific EB region)
6	F20B4.2	F20B4.2	n/a	chrX 17,704,274
7	atg-16.1	F02E8.5	n/a	chrX 4,461,104	atg-16.1 encodes a divergent ortholog of the autophagic budding yeast protein Atg16p, and of human ATG16L1 (OMIM:610767, associated with Crohn disease) and ATG16L2; ATG-16.1 is paralogous to ATG-16.2; ATG-16.1 is expressed in larval and adult intestine, renal gland cells, stomato-intestinal muscle, anal depressor muscle, and head mesodermal cell; ATG-16.1 has no obvious function in mass RNAi assays.
8	F42A6.6	F42A6.6	n/a	chrIV 3,336,420	contains similarity to Pfam domain PF05603 Protein of unknown function (DUF775) contains similarity to Interpro domain IPR008493 (Protein of unknown function DUF775)
9	T22G5.3	T22G5.3	n/a	chrV 13,882,397	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
10	F23B2.3	F23B2.3	n/a	chrIV 9,134,019	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
11	T24H10.1	T24H10.1	n/a	chrII 9,099,835	contains similarity to Pfam domains PF07500 (Transcription factor S-II (TFIIS), central domain) , PF08711 (Transcription elongation factor S-II protein N terminal) , PF01096 (Transcription factor S-II (TFIIS)) contains similarity to Interpro domains IPR001222 (Zinc finger, TFIIS-type), IPR003618 (Transcription elongation factor S-II, central region), IPR014754 (Transcription elongation factor, TFIIS, N-terminal, fungal-type), IPR003617 (Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type), IPR014765 (Transcription elongation factor, TFIIS/CRSP70, N-terminal), IPR016492 (Transcription elongation factor, IIS), IPR006289 (Transcription elongation factor, TFIIS), IPR010990 (Transcription elongation factor, TFIIS/elongin A/CRSP70, N-terminal)
12	lips-12	T13B5.6	n/a	chrII 1,113,234	C. elegans LIPS-12 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
13	F21G4.5	F21G4.5	n/a	chrX 9,906,914	contains similarity to Interpro domain IPR007087 (Zn-finger, C2H2 type)
14	D1007.8	D1007.8	n/a	chrI 4,604,894	contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold)
15	clec-165	F38A1.10	n/a	chrIV 1,246,135	C. elegans CLEC-165 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001680 (WD40 repeat), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
16	C29F9.8	C29F9.8	n/a	chrIII 96,559
17	K09A9.4	K09A9.4	n/a	chrX 15,593,283	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domain IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
18	F12A10.1	F12A10.1	n/a	chrII 5,497,839	contains similarity to Oryza sativa subsp indica Putative uncharacterized protein.; TR:A2YC95
19	Y48E1C.2	Y48E1C.2	n/a	chrII 13,426,646	contains similarity to Pfam domain PF07942 N2227-like protein contains similarity to Interpro domain IPR012901 (N2227-like)
20	C43H6.7	C43H6.7	n/a	chrX 2,400,426	contains similarity to Pfam domain PF01529 DHHC zinc finger domain contains similarity to Interpro domains IPR001594 (Zinc finger, DHHC-type), IPR016201 (Plexin-like fold)
21	bath-39	F25H9.4	n/a	chrV 13,460,604	C. elegans BATH-39 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
22	math-21	C40D2.3	n/a	chrII 1,994,852	C. elegans MATH-21 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
23	F53B1.2	F53B1.2	n/a	chrX 2,110,346	contains similarity to Pfam domains PF07647 (SAM domain (Sterile alpha motif)) , PF00536 (SAM domain (Sterile alpha motif)) contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase), IPR013761 (Sterile alpha motif-type), IPR001660 (Sterile alpha motif SAM), IPR011510 (Sterile alpha motif homology 2)
24	R07E5.15	R07E5.15	n/a	chrIII 4,401,952
25	srv-17	C06E7.7	n/a	chrIV 5,868,915	C. elegans SRV-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
26	lin-59	T12F5.4	n/a	chrI 3,717,339	C. elegans LIN-59 protein; contains similarity to Pfam domains PF01426 (BAH domain) , PF00628 (PHD-finger) , PF00856 (SET domain) contains similarity to Interpro domains IPR001214 (SET), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR001025 (Bromo adjacent region), IPR011011 (Zinc finger, FYVE/PHD-type), IPR006560 (AWS)
27	glt-7	W03G1.1	n/a	chrIV 533,911	C. elegans GLT-7 protein; contains similarity to Pfam domain PF00375 Sodium:dicarboxylate symporter family contains similarity to Interpro domain IPR001991 (Sodium:dicarboxylate symporter)
28	rib-2	K01G5.6	n/a	chrIII 10,744,609	The rib-2 gene encodes an ortholog of human EXT2, which when mutated leads to hereditary multiple exostoses, type II (OMIM:133701).
29	str-161	T08B6.3	n/a	chrIV 4,903,231	C. elegans STR-161 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	ZK669.2	ZK669.2	n/a	chrII 7,937,580	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
31	sru-16	Y45F10B.4	n/a	chrIV 13,581,181	C. elegans SRU-16 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
32	R148.2	R148.2	n/a	chrIII 3,184,321
33	ZK1225.1	ZK1225.1	n/a	chrI 13,206,699	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
34	F41G4.5	F41G4.5	n/a	chrX 16,831,782
35	srz-74	K03D3.1	n/a	chrIV 16,330,219	C. elegans SRZ-74 protein ;
36	srt-7	C50H11.4	n/a	chrV 3,082,398	C. elegans SRT-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000408 (Regulator of chromosome condensation, RCC1)
37	C04G6.4	C04G6.4	n/a	chrII 5,082,452	contains similarity to Interpro domain IPR000694 (Proline-rich region)
38	F53A2.9	F53A2.9	n/a	chrIII 13,357,930	contains similarity to Pfam domain PF00646 (F-box domain)
39	srj-55	Y45G12A.1	n/a	chrV 2,857,011	C. elegans SRJ-55 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	nhr-256	ZK697.2	n/a	chrV 1,745,848	C. elegans NHR-256 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	EEED8.4	EEED8.4	n/a	chrII 5,410,795	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
42	K04G11.1	K04G11.1	n/a	chrX 14,335,998	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
43	srt-13	ZC142.1	n/a	chrV 4,249,044	C. elegans SRT-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000539 (Frizzled protein)
44	F48G7.4	F48G7.4	n/a	chrV 620,860
45	sprr-2	F42D1.3	n/a	chrX 14,802,137	C. elegans SPRR-2 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
46	ddl-2	Y48E1B.1	n/a	chrII 13,545,140	C. elegans DDL-2 protein; contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR000381 (Inhibin, beta B subunit), IPR000694 (Proline-rich region), IPR003882 (Pistil-specific extensin-like protein)
47	T26A5.8	T26A5.8	n/a	chrIII 6,462,478	contains similarity to Pfam domain PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone contains similarity to Interpro domains IPR009072 (Histone-fold), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
48	Y17G7B.3	Y17G7B.3	n/a	chrII 11,990,838	Y17G7B.3 is orthologous to the human gene HYDROXYACYLGLUTATHIONE HYDROLASE (HAGH; OMIM:138760), which when mutated leads to disease.
49	EEED8.6	EEED8.6	n/a	chrII 5,385,733	EEED8.6 encodes an ATP/ADP-activated metallocarboxypeptidase, orthologous to mammalian AGBL4 proteins, that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; recombinant EEED8.6 is active in vitro on several different C-terminal amino acids of synthetic peptide substrates (with carboxypeptidase A- and B-like, but not O-like specificity); unlike most carboxypeptidases, but like tubulin carboxypeptidase, EEED8.6 is inhibited by high salt or by Z-Glu-Tyr dipeptide; EEED8.6 and its mammalian AGBL4 orthologs, along with other proteins such as mammalian AGBL5, comprise a M14D2 peptidase subfamily; by homolog-based structural modelling, EEED8.6 is predicted to have an unusually open active site.
50	sri-7	T06E6.4	n/a	chrV 15,401,049	C. elegans SRI-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)