UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C28C12.2	C28C12.2	2e-98	chrIV 8,499,682
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	puf-5	F54C9.8	n/a	chrII 8,576,562	C. elegans PUF-5 protein; contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	F22B3.4	F22B3.4	n/a	chrIV 11,411,714	F22B3.4 encodes a putative glucosamine-fructose 6-phosphate aminotransferase, paralogous to F07A11.2, thought to catalyse the first step of the hexosamine pathway to UDP-N-acetylglucosamine or UDP-N-acetylgalactosamine; F22B3.4 transcripts are enriched during oogenesis; F22B3.4(RNAi) animals have an osmotically-sensitive embryonic lethal phenotype, presumably because of defects in chitin and eggshell synthesis.
6	oma-2	ZC513.6	n/a	chrV 8,030,304	The oma-2 gene encodes a zinc finger protein of the TIS11 finger type that is paralogous to OMA-1; while either oma-1 or oma-2 individually have no obvious mutant phenotype, a normal copy of at least one of these genes is required for oocyte maturation.
7	vit-1	K09F5.2	n/a	chrX 7,730,476	C. elegans VIT-1 protein; contains similarity to Pfam domains PF00094 (von Willebrand factor type D domain) , PF09172 (Domain of unknown function (DUF1943)) , PF01347 (Lipoprotein amino terminal region) contains similarity to Interpro domains IPR015819 (Lipid transport protein, beta-sheet shell), IPR011030 (Vitellinogen, superhelical), IPR015818 (Vitellinogen, open beta-sheet, subdomain 2), IPR001747 (Lipid transport protein, N-terminal), IPR015816 (Vitellinogen, beta-sheet N-terminal), IPR001846 (von Willebrand factor, type D), IPR015255 (Vitellinogen, open beta-sheet)
8	F53H4.2	F53H4.2	n/a	chrX 15,857,486	contains similarity to Interpro domains IPR001220 (Legume lectin, beta domain), IPR000209 (Serine proteases, subtilase family)
9	T01C3.3	T01C3.3	n/a	chrV 14,992,169	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
10	C35B1.4	C35B1.4	n/a	chrIV 4,079,997
11	F54F7.3	F54F7.3	n/a	chrX 11,849,694	contains similarity to Amsacta moorei entomopoxvirus AMV135.; TR:Q9EMR4
12	F55B11.2	F55B11.2	n/a	chrIV 14,422,746	contains similarity to Xenopus laevis Similar to LGN protein.; TR:Q8AVU7
13	vit-5	C04F6.1	n/a	chrX 3,406,006	vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent; by homology, VIT-5 is predicted to function as a lipid transport protein; loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth; VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes.
14	T27A10.6	T27A10.6	n/a	chrX 3,592,684	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
15	Y62H9A.4	Y62H9A.4	n/a	chrX 11,880,601	contains similarity to Branchiostoma floridae Homeobox protein DLL homolog.; SW:HMDL_BRAFL
16	C49F5.7	C49F5.7	n/a	chrX 11,995,234	contains similarity to Homo sapiens Similar to PDZ domain proteins; ENSEMBL:ENSP00000298474
17	W05F2.3	W05F2.3	n/a	chrI 3,368,102
18	Y45F10C.4	Y45F10C.4	n/a	chrIV 13,663,763	contains similarity to Pfam domain PF07403 Protein of unknown function (DUF1505) contains similarity to Interpro domain IPR009981 (Protein of unknown function DUF1505)
19	mei-2	F57B10.12	n/a	chrI 6,565,308	mei-2 encodes a novel protein that contains a region similar to the p80-targeting subunit of katanin that is required for embryonic viability, alignment of chromosomes at the metaphase plate, and establishment of the oocyte meiotic spindle together with MEI-1; can interact with MEI-1 in HeLa cells and this complex can function to disassemble microtubules, expressed in the germ line, throughout the cytoplasm of most mature oocytes within the proximal gonad, and localization is mutually dependent upon MEI-1
20	gln-5	F26D10.10	n/a	chrIV 17,272,909	C. elegans GLN-5 protein; contains similarity to Pfam domains PF03951 (Glutamine synthetase, beta-Grasp domain) , PF00120 (Glutamine synthetase, catalytic domain) contains similarity to Interpro domains IPR008147 (Glutamine synthetase, beta-Grasp), IPR014746 (Glutamine synthetase/guanido kinase, catalytic region), IPR008146 (Glutamine synthetase, catalytic region)
21	hex-5	Y70D2A.2	n/a	chrX 14,903,528	hex-5 encodes a beta-N-acetylhexosaminidase.
22	Y62H9A.6	Y62H9A.6	n/a	chrX 11,883,508	contains similarity to Brucella melitensis Hypothetical cytosolic protein BMEI0237.; TR:Q8YJ49
23	W02D9.7	W02D9.7	n/a	chrI 12,559,462	contains similarity to Vibrio vulnificus Septum formation inhibitor-activating ATPase.; TR:Q8DFS3
24	B0304.2	B0304.2	n/a	chrII 4,524,073
25	C17E4.3	C17E4.3	n/a	chrI 9,417,878	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
26	cpg-3	R06C7.4	n/a	chrI 7,245,503	cgp-3 encodes a putatively secreted protein with an N-terminal low-complexity domain containing 15 potential chondroitin attachment sites, and a C-terminal EGF-like region; cpg-3 mRNA is enriched in oogenesis, but CPG-3 has no obvious function in mass RNAi assays.
27	tbh-1	H13N06.6	n/a	chrX 15,501,790	tbh-1 encodes a putative dopamine beta-hydroxylate orthologous to human DBH (OMIM:609312, mutated in dopamine beta-hydroxylase deficiency).
28	F49E12.1	F49E12.1	n/a	chrII 8,402,502	contains similarity to Pfam domains PF01549 (ShK domain-like) , PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal), IPR003582 (Metridin-like ShK toxin)
29	T01H3.4	T01H3.4	n/a	chrII 7,881,603	T01H3.4 encodes an unfamiliar protein; T01H3.4 and T01H3.5 share an operon divergently transcribed from another operon containing vha-4.
30	C37C3.9	C37C3.9	n/a	chrV 7,853,081	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
31	C14B1.2	C14B1.2	n/a	chrIII 3,702,706	contains similarity to Bacillus anthracis Hypothetical protein.; TR:Q81T15
32	W02D9.5	W02D9.5	n/a	chrI 12,561,291	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
33	K07A1.6	K07A1.6	n/a	chrI 9,592,533	K07A1.6 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; K07A1.6 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; K07A1.6 has no obvious function in mass RNAi assays.
34	H02I12.1	H02I12.1	n/a	chrIV 11,375,266	H02I12.1 encodes a large (1319-residue) protein with 12 chitin-binding peritrophin-A domains; H02I12.1(RNAi) animals have an osmotically-sensitive embryonic lethal phenotype, perhaps because of defects in chitin and eggshell synthesis; like CEJ-1 and CPG-2, H02I12.1 may participate in eggshell synthesis and early embryonic development; H02I12.1's multiple peritrophin-A domains might enable mechanical cross-linking of chitin.
35	F20H11.5	F20H11.5	n/a	chrIII 6,588,571	F20H11.5 encodes a putative secreted D-aspartate oxidase (DASPO), paralogous to C47A10.5 and F18E3.7; recombinant F20H11.5 protein is insoluble when expressed in E. coli, and thus has not yet been tested in vitro for activity; F20H11.5 is expressed in a head mesodermal cell, hypodermis, other head cells, and vulva.
36	K07A1.13	K07A1.13	n/a	chrI 9,584,354	contains similarity to White spot syndrome virus Wsv319.; TR:Q8VAS3
37	plk-3	F55G1.8	n/a	chrIV 7,472,120	C. elegans PLK-3 protein; contains similarity to Pfam domains PF00659 (POLO box duplicated region) (2), PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR017450 (POLO box), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000959 (POLO box duplicated region)
38	dod-23	F49E12.2	n/a	chrII 8,398,700	C. elegans DOD-23 protein ;
39	F48E3.4	F48E3.4	n/a	chrX 7,494,618	contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine)
40	B0513.4	B0513.4	n/a	chrIV 13,880,800	contains similarity to Ixodes scapularis Putative secreted protein.; TR:Q8MVF5
41	cpg-2	B0280.5	n/a	chrIII 7,102,966	cpg-2 encodes a protein with six chitin-binding peritrophin-A domains and three mucin-like regions; CPG-2 is individually dispensable for normal embryonic development; however, CPG-2 and CPG-1 are jointly required for osmotic integrity of early embryos, error-free chromosomal segregation during meiosis, polar body extrusion, association of the sperm pronucleus/centrosome complex (SPCC) with the early embryonic cortex, localization of PAR-2 in early embryos, posterior localization of P granules or PIE-1, and pseudocleavage; CPG-2, like CPG-1, is covalently linked to chondroitin, which itself is required for vulval morphogenesis, polar-body extrusion, and separation of the eggshell from the embryonic plasma membrane; cpg-2 mRNA, like that of cpg-1, is expressed specifically in the adult hermaphrodite germ line and is bound by GLD-1; CPG-2 has 34 potential chondroitin attachment sites, four of them verified by mass spectrometry, and transgenic CPG-2 synthesized in mammalian cells carries chondroitin sulfate chains; CPG-2's multiple peritrophin-A domains may enable mechanical cross-linking of chitin.
42	C03D6.6	C03D6.6	n/a	chrI 9,657,459	contains similarity to Saccharomyces cerevisiae Involved in cell cycle control and ion homeostasis; SGD:YKR072C
43	C25A8.4	C25A8.4	n/a	chrIV 7,006,427	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
44	F57C2.4	F57C2.4	n/a	chrII 14,525,575	contains similarity to Homo sapiens Crumbs protein homolog 1 precursor; ENSEMBL:ENSP00000256772
45	C16C8.4	C16C8.4	n/a	chrII 3,443,969	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
46	F41H10.5	F41H10.5	n/a	chrIV 5,361,533	contains similarity to Interpro domain IPR006634 (TRAM, LAG1 and CLN8 homology)
47	tag-68	F37D6.6	n/a	chrI 10,503,512	C. elegans TAG-68 protein; contains similarity to Pfam domains PF03166 (MH2 domain) , PF03165 (MH1 domain) contains similarity to Interpro domains IPR013019 (MAD homology, MH1), IPR008984 (SMAD/FHA domain), IPR001132 (SMAD domain, Dwarfin-type), IPR017855 (SMAD domain-like), IPR013790 (Dwarfin), IPR003619 (MAD homology 1, Dwarfin-type)
48	D1054.11	D1054.11	n/a	chrV 10,794,334	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
49	col-178	C34F6.2	n/a	chrX 11,199,889	C. elegans COL-178 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
50	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)