UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nex-3	C28A5.3	6e-178	chrIII 4,443,071	nex-3 encodes an annexin, a member of a family of calcium-dependent phospholipid binding proteins; by homology, NEX-3 could function in a number of processes, such as membrane fusion, cytoskeletal interactions, and intracellular signaling; however, as loss of nex-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of NEX-3 in C. elegans development and/or behavior is not yet known.
2	T05H10.1	T05H10.1	n/a	chrII 8,044,949	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR011051 (Cupin, RmlC-type)
3	Y57G7A.8	Y57G7A.8	n/a	chrII 1,291,464
4	srx-10	R10D12.4	n/a	chrV 13,945,845	C. elegans SRX-10 protein; contains similarity to Pfam domain PF08560 Protein of unknown function (DUF1757) contains similarity to Interpro domain IPR013869 (Protein of unknown function DUF1757)
5	fbxa-197	T06C12.4	n/a	chrV 15,868,291	C. elegans FBXA-197 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
6	K05C4.4	K05C4.4	n/a	chrI 14,736,077	contains similarity to Homo sapiens Hypothetical protein KIAA1185; ENSEMBL:ENSP00000253061
7	sqv-3	R10E11.4	n/a	chrIII 9,779,478	sqv-3 encodes a beta(1,4)-galactosyltransferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos, vulval morphogenesis, and chondroitin synthesis; SQV-3 is orthologous to human human galactosyltransferase I (B4GALT7; OMIM:604327, mutated in the progeroid form of Ehlers-Danlos syndrome); sqv-3 transgenically rescues hamster cells lacking galactosyl transferase I; the common requirement for SQV-3 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
8	F49C5.5	F49C5.5	n/a	chrII 12,546,186
9	mxl-2	F40G9.11	n/a	chrIII 187,571	C. elegans MXL-2 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
10	F21F8.2	F21F8.2	n/a	chrV 8,275,167	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001461 (Peptidase A1)
11	D1086.4	D1086.4	n/a	chrV 14,091,601	contains similarity to Saccharomyces cerevisiae GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2; SGD:YAL035W
12	F46F11.8	F46F11.8	n/a	chrI 5,625,448
13	tbx-36	ZK829.5	n/a	chrIV 11,951,305	C. elegans TBX-36 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
14	T14G10.7	T14G10.7	n/a	chrIV 10,148,080	contains similarity to Bos taurus GPI transamidase component PIG-S (Phosphatidylinositol-glycansbiosynthesis class S protein).; SW:Q3SZL5
15	W03G9.2	W03G9.2	n/a	chrI 4,963,346	contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR001545 (Gonadotropin, beta chain)
16	hop-1	C18E3.8	n/a	chrI 4,209,468	hop-1 encodes one of three C. elegans presenilins (the other two presenilins are encoded by sel-12 and spe-4); originally identified on the basis of its sequence similarity to SEL-12 and the human PS1 and PS2 presenilins, HOP-1 has been shown to function redundantly with SEL-12 in embryonic, larval, and germline development and thus, to likely function by regulating LIN-12/GLP-1 signaling; in addition, hop-1 can functionally substitute for sel-12 by rescuing the egg-laying and vulval development defects of sel-12 mutants; hop-1 transcription appears to be regulated, at least in part, by the C. elegans spr genes, some of which encode orthologs of the mammalian CoREST repressor complex.
17	K02B7.2	K02B7.2	n/a	chrII 14,692,031	contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
18	F30F8.3	F30F8.3	n/a	chrI 7,836,374	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
19	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
20	ZC155.4	ZC155.4	n/a	chrIII 5,213,465	contains similarity to Pfam domain PF03009 Glycerophosphoryl diester phosphodiesterase family contains similarity to Interpro domain IPR004129 (Glycerophosphoryl diester phosphodiesterase)
21	ani-2	K10B2.5	n/a	chrII 6,363,196	ani-2 encodes one of three C. elegans anillins; ANI-2 activity is required in the syncytial gonad for proper gonad structure and oocyte formation; specifically, ANI-2 appears to be required for maintaining the structure of the rachis, the syncytial compartment of germline cytoplasm that connects developing ooctyes; in the adult gonad, ANI-2 localizes to the surface of the rachis.
22	F33G12.2	F33G12.2	n/a	chrII 5,030,810	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
23	F26H9.4	F26H9.4	n/a	chrI 9,306,326	contains similarity to Pfam domain PF01467 Cytidylyltransferase contains similarity to Interpro domains IPR005248 (Probable nicotinate-nucleotide adenylyltransferase), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004820 (Cytidylyltransferase)
24	C42C1.8	C42C1.8	n/a	chrIV 12,292,136	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
25	F25H9.6	F25H9.6	n/a	chrV 13,467,638	contains similarity to Pfam domain PF02441 Flavoprotein contains similarity to Interpro domain IPR003382 (Flavoprotein)
26	F26F12.2	F26F12.2	n/a	chrV 5,838,075
27	srv-22	H04M03.9	n/a	chrIV 5,879,196	C. elegans SRV-22 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
28	F07G11.2	F07G11.2	n/a	chrV 7,304,229	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
29	D1022.5	D1022.5	n/a	chrII 7,458,058
30	M03C11.2	M03C11.2	n/a	chrIII 10,402,129	contains similarity to Pfam domain PF06733 DEAD_2 contains similarity to Interpro domains IPR014013 (Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type), IPR010614 (DEAD2), IPR006554 (Helicase-like, DEXD box c2 type), IPR006555 (Helicase, ATP-dependent, c2 type), IPR014001 (DEAD-like helicase, N-terminal), IPR013020 (DNA helicase (DNA repair), Rad3 type)
31	F27B3.5	F27B3.5	n/a	chrIII 6,560,937	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
32	C17H12.2	C17H12.2	n/a	chrIV 6,788,223	contains similarity to Drosophila melanogaster Flybase gene name is CG7289-PA;; FLYBASE:CG7289
33	ccdc-55	C16C10.6	n/a	chrIII 4,167,827	C. elegans CCDC-55 protein ; contains similarity to Mus musculus Coiled-coil domain-containing protein 55.; SW:Q5NCR9
34	F37B12.3	F37B12.3	n/a	chrII 9,040,539	contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
35	K11H12.6	K11H12.6	n/a	chrIV 667,977
36	Y102A5C.2	Y102A5C.2	n/a	chrV 16,919,147	contains similarity to Saccharomyces cerevisiae anti-silencing protein that causes depression of silent loci when overexpressed; SGD:YJL115W
37	lips-17	R07G3.2	n/a	chrII 7,609,466	C. elegans LIPS-17 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domains IPR002918 (Lipase, class 2), IPR008262 (Lipase, active site)
38	B0564.2	B0564.2	n/a	chrIV 13,107,893	contains similarity to Pfam domain PF03171 2OG-Fe(II) oxygenase superfamily contains similarity to Interpro domain IPR005123 (2OG-Fe(II) oxygenase)
39	F57C9.7	F57C9.7	n/a	chrI 4,825,902
40	his-44	F08G2.1	n/a	chrII 13,826,823	his-44 encodes an H2B histone.
41	F52C6.4	F52C6.4	n/a	chrII 1,923,563	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
42	bath-27	F14D2.1	n/a	chrII 3,360,782	C. elegans BATH-27 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
43	kbp-3	F26H11.1	n/a	chrII 14,389,558	C. elegans KBP-3 protein ; contains similarity to Homo sapiens similar to Kinesin heavy chain isoform 5C; ENSEMBL:ENSP00000334176
44	F13E9.1	F13E9.1	n/a	chrIV 10,868,951	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (4), PF00787 (PX domain) contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR001683 (Phox-like), IPR003591 (Leucine-rich repeat, typical subtype)
45	ztf-9	ZK287.6	n/a	chrV 9,691,558	C. elegans ZTF-9 protein; contains similarity to Interpro domain IPR015880 (Zinc finger, C2H2-like)
46	M05D6.2	M05D6.2	n/a	chrII 8,469,058	contains similarity to Pfam domain PF05794 T-complex protein 11 contains similarity to Interpro domain IPR008862 (T-complex 11)
47	cdk-5	T27E9.3	n/a	chrIII 13,465,418	cdk-5 encodes a putative homolog of cyclin dependent kinase 5 that affects pronuclear migration and rotation in one-cell embryos and may affect neuronal development; expressed in neurons.
48	nth-1	R10E4.5	n/a	chrIII 4,292,462	C. elegans NTH-1 protein; contains similarity to Pfam domains PF00633 (Helix-hairpin-helix motif) , PF00730 (HhH-GPD superfamily base excision DNA repair protein) contains similarity to Interpro domains IPR011257 (DNA glycosylase), IPR003651 (Iron-sulphur cluster loop), IPR000445 (Helix-hairpin-helix motif), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR004036 (Endonuclease III, conserved site-2), IPR003265 (HhH-GPD)
49	F02E9.7	F02E9.7	n/a	chrI 8,414,687	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domain IPR004843 (Metallophosphoesterase)
50	Y49A10A.1	Y49A10A.1	n/a	chrX 10,359,445	contains similarity to Pfam domain PF06565 Repeat of unknown function (DUF1126) contains similarity to Interpro domains IPR010554 (Protein of unknown function DUF1126), IPR006602 (Region of unknown function DM10)