UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C27C7.5	C27C7.5	4e-167	chrI 11,425,014	contains similarity to Pfam domains PF00337 (Galactoside-binding lectin) , PF08277 (PAN-like domain) contains similarity to Interpro domains IPR006583 (CW), IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
2	F35E12.4	F35E12.4	n/a	chrV 13,732,426	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR003951 (Peptidase C58, Yersinia/Haemophilus virulence surface antigen), IPR003366 (CUB-like region)
3	sfxn-1.4	C47D12.3	n/a	chrII 11,680,034	C. elegans SFXN-1.4 protein; contains similarity to Pfam domain PF03820 Tricarboxylate carrier contains similarity to Interpro domain IPR004686 (Tricarboxylate/iron carrier)
4	F55G11.1	F55G11.1	n/a	chrIV 12,945,773	contains similarity to Magnetospirillum magnetotacticum MagA protein.; TR:Q8GRF6
5	stdh-1	C06B3.4	n/a	chrV 13,907,215	stdh-1 encodes a putative steroid dehydrogenase required for normally short lifespan; STDH-1 is orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767 and STDH-2/-4; STDH-1 is expressed in larval intestine, and in both larval and adult body wall muscle and neurons.
6	K07H8.7	K07H8.7	n/a	chrIV 8,259,664	contains similarity to Interpro domain IPR000079 (High mobility group protein HMG14 and HMG17)
7	sra-3	AH6.7	n/a	chrII 9,539,969	C. elegans SRA-3 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
8	rbx-2	R10A10.2	n/a	chrI 6,421,299	The R10A10.2 gene encodes an ortholog of the mammalian zinc RING finger protein SAG, which protects cells from apoptosis induced by redox agents and is a component of ubiquitin-ligase (E3) complexes; mammalian SAG binds to the yeast Cul1 protein, complements the lethality of a mutation in yeast Sag, and (when bound to yeast Cul1) has ubiquitin ligase activity and promotes poly-ubiquitination of E2/Cdc34.
9	C40D2.4	C40D2.4	n/a	chrII 2,000,282	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
10	H05L14.1	H05L14.1	n/a	chrI 7,974,757	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
11	C10G8.2	C10G8.2	n/a	chrV 5,314,980	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domain IPR002223 (Proteinase inhibitor I2, Kunitz metazoa)
12	F18A12.6	F18A12.6	n/a	chrII 3,401,335	F18A12.6 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.6 has no clear orthologs in other organisms.
13	F46F5.10	F46F5.10	n/a	chrII 824,543	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
14	cpb-1	C40H1.1	n/a	chrIII 9,323,513	cpb-1 encodes a cytoplasmic polyadenylation element binding (CPEB) protein homolog involved in two steps of spermatogenesis; two CPEB proteins have distinct functions in spermatogenesis, with FOG-1 specifying sperm cell fate, and CPB-1 conversely executing that decision, being required for progression through meiosis; cpb-1(RNAi) spermatocytes fail to undergo meiotic cell divisions; CPB-1 protein is present in the germ line just prior to overt spermatogenesis, but once sperm differentiation begins, CPB-1 disappears; CPB-1 physically interacts with EBF, which, like CPEB, regulates genes by binding the 3' UTRs of mRNAs; while CPB-1 is required for spermatogenesis, it is dispensable for oogenesis; this is in contrast to CPEBs in vertebrates (Xenopus), arthropods (Drosophila), and molluscs (Spisula), which all participate in oogenesis.
15	R01H2.2	R01H2.2	n/a	chrIII 7,057,468	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
16	F56F3.3	F56F3.3	n/a	chrIII 4,458,938	contains similarity to Drosophila dasycnemia Wingless (Fragment).; TR:O46305
17	Y37A1A.2	Y37A1A.2	n/a	chrIV 13,909,126	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR016196 (MFS general substrate transporter)
18	C34C12.4	C34C12.4	n/a	chrIII 3,468,832	contains similarity to Homo sapiens Uncharacterized protein C4orf34; ENSEMBL:ENSP00000295958
19	sru-35	C33D9.4	n/a	chrIV 8,789,328	C. elegans SRU-35 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
20	hlh-4	T05G5.2	n/a	chrIII 9,738,064	C. elegans HLH-4 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR015660 (Achaete-scute transcription factor related), IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR000694 (Proline-rich region), IPR011598 (Helix-loop-helix DNA-binding)
21	fbxa-30	ZC47.4	n/a	chrIII 1,275,041	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
22	R09D1.13	R09D1.13	n/a	chrII 9,444,567	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
23	C45G9.8	C45G9.8	n/a	chrIII 5,052,953
24	T04G9.6	T04G9.6	n/a	chrX 783,076	contains similarity to Interpro domain IPR001759 (Pentaxin)
25	C09B9.7	C09B9.7	n/a	chrIV 5,058,402	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
26	nhr-169	C54C8.1	n/a	chrI 12,443,002	C. elegans NHR-169 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
27	srbc-12	K09C6.4	n/a	chrV 850,574	C. elegans SRBC-12 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR003492 (Batten's disease protein Cln3)
28	try-6	F48A9.3	n/a	chrI 6,586,594	C. elegans TRY-6 protein; contains similarity to Pfam domains PF00089 (Trypsin) , PF03761 (Domain of unknown function (DUF316)) contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
29	F27C8.5	F27C8.5	n/a	chrIV 9,591,134	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
30	K02F6.7	K02F6.7	n/a	chrII 2,527,240
31	T11F1.2	T11F1.2	n/a	chrII 2,957,123	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
32	W09C3.8	W09C3.8	n/a	chrI 4,716,751
33	skr-20	R12H7.5	n/a	chrX 13,223,155	The skr-20 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-20(RNAi) animals are at least superficially normal.
34	C18H2.4	C18H2.4	n/a	chrIII 7,697,463	C18H2.4 is orthologous to the human gene GLOMULIN (FAP48; OMIM:601749), which when mutated leads to disease.
35	F42G8.9	F42G8.9	n/a	chrIV 8,117,087
36	grd-8	C37C3.4	n/a	chrV 7,843,402	grd-8 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-8 is expressed in larval intestine and neurons; the grd-8 gene is directly bound by DAF-12 and requires DAF-12 for full transcription; GRD-8's Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-8 is weakly required for normal molting; GRD-8 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
37	BE10.3	BE10.3	n/a	chrIII 12,810,237	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
38	Y65A5A.2	Y65A5A.2	n/a	chrIV 16,413,511	contains similarity to Saccharomyces cerevisiae Required for invasion and pseudohyphae formation in response to nitrogen starvation; SGD:YIR019C
39	F28B1.4	F28B1.4	n/a	chrV 17,056,226	contains similarity to Archaeoglobus fulgidus Ferredoxin (FDX-2).; TR:O30071
40	C18H2.3	C18H2.3	n/a	chrIII 7,685,691	contains similarity to Pfam domains PF00023 (Ankyrin repeat) (2), PF00533 (BRCA1 C Terminus (BRCT) domain) (2)contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001357 (BRCT)
41	srz-20	F56D6.5	n/a	chrIV 3,916,211	C. elegans SRZ-20 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR001411 (Tetracycline resistance protein, TetB), IPR000576 (Proton/sugar symporter, LacY)
42	C01H6.6	C01H6.6	n/a	chrI 7,223,298	C01H6.6 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C33D12.2, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C01H6.6 may participate in metal homoeostasis; C01H6.6, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C01H6.6 has no obvious function in RNAi assays.
43	Y62H9A.1	Y62H9A.1	n/a	chrX 11,876,371	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	Y44A6D.6	Y44A6D.6	n/a	chrV 20,807,147	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
45	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
46	ins-37	F08G2.6	n/a	chrII 13,835,294	ins-37 encodes an insulin-like peptide.
47	str-96	T10H4.2	n/a	chrV 15,293,203	C. elegans STR-96 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	srg-56	C24B9.10	n/a	chrV 2,736,901	C. elegans SRG-56 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
49	twk-6	F17C8.5	n/a	chrIII 4,743,772	twk-6 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; as loss of TWK-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of TWK-6 in C. elegans development and/or behavior is not yet known; TWK-6 may, however, function redundantly with other TWK channels; TWK-6 is expressed in the hypodermis.
50	K02D10.2	K02D10.2	n/a	chrIII 8,770,897