UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C26H9A.2	C26H9A.2	0	chrIV 12,657,776	contains similarity to Interpro domains IPR016024 (Armadillo-type fold), IPR008985 (Concanavalin A-like lectin/glucanase)
2	K02H8.1	K02H8.1	n/a	chrX 17,004,963	K02H8.1 encodes, by alternative splicing, two isoforms of a putative MUSCLEBLIND-type mRNA splicing regulator required in adults for normal muscle dense body organization, locomotion, and vulval morphogenesis; K02H8.1 is orthologous to Drosophila MBL and human MBNL1 (OMIM:606516), MBNL2 (OMIM:607327), and MBNL3 (OMIM:300413); K02H8.1 is transcribed in larvae and adults; K02H8.1(RNAi) animals show protruding vulvae, progressive uncoordination, and disordered dense bodies; while K02H8.1 is required in adults, it is dispensable in larvae, perhaps reflecting a progressive muscle dystrophy in K02H8.1(RNAi) animals.
3	F10G8.2	F10G8.2	n/a	chrI 10,022,221	contains similarity to Interpro domain IPR011009 (Protein kinase-like)
4	T05A1.3	T05A1.3	n/a	chrIV 9,563,673	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
5	nhr-171	C54F6.8	n/a	chrV 7,512,900	C. elegans NHR-171 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
6	ceh-12	F33D11.4	n/a	chrI 5,841,090	ceh-12 encodes a homeobox protein orthologous to human HLXB9 (OMIM:142994, mutated in Currarino syndrome) that is required for normal synaptic inputs to motor neurons VA2-VA10 (sisters to VB3-VB11); ceh-12 is expressed in VB motor neurons, but repressed in their VA siblings by UNC-4 and UNC-37; unc-4 or unc-37 mutants show ectopic CEH-12 expression in VA neurons, which is both necessary and sufficient to induce VA neurons to form gap junctions with normally VB-specific interneurons; ceh-12 mutations have no grossly obvious phenotype, and have no effect on del-1 or acr-5 repression in VB neurons, but do suppress the backward movement defect of unc-4 mutants, and do derepress vab-7 (normally restricted to DB and VC motor neurons); CEH-12, like other HLXB9 orthologs, has an N-terminal eh1 domain that may interact with UNC-37/Groucho, and that may indicate CEH-12 to be a transcriptional repressor.
7	Y113G7A.12	Y113G7A.12	n/a	chrV 20,140,914
8	spe-19	Y113G7A.10	n/a	chrV 20,039,581	C. elegans SPE-19 protein ;
9	C45G9.11	C45G9.11	n/a	chrIII 5,066,320
10	K02D10.3	K02D10.3	n/a	chrIII 8,771,549
11	F49B2.6	F49B2.6	n/a	chrI 14,335,445	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
12	flnb-1	C23F12.2	n/a	chrX 9,402,619	C. elegans FLNB-1 protein; contains similarity to Pfam domains PF00630 (Filamin/ABP280 repeat) (2), PF00307 (Calponin homology (CH) domain) (3)contains similarity to Interpro domains IPR001298 (Filamin/ABP280 repeat), IPR014756 (Immunoglobulin E-set), IPR013783 (Immunoglobulin-like fold), IPR000694 (Proline-rich region), IPR016146 (Calponin-homology), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR001715 (Calponin-like actin-binding)
13	bath-25	T27C10.4	n/a	chrI 10,877,883	C. elegans BATH-25 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00036 (EF hand) (2), PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
14	F22E5.8	F22E5.8	n/a	chrII 2,640,990	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
15	Y49E10.24	Y49E10.24	n/a	chrIII 12,486,416	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
16	F49F1.6	F49F1.6	n/a	chrIV 4,122,198	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
17	Y106G6G.2	Y106G6G.2	n/a	chrI 10,325,764	contains similarity to Interpro domain IPR000904 (SEC7-like)
18	ndx-2	W02G9.1	n/a	chrV 2,664,041	ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
19	oat-1	T01B11.7	n/a	chrIV 8,468,702	oat-1 encodes a transmembrane organic anion transporter; although loss of oat-1 activity via large-scale RNAi screens results in no obvious abnormalities, when expressed in mammalian cells OAT-1 can transport a variety of structurally diverse organic anions via an anion exchange mechanism that is functionally coupled to a sodium-coupled dicarboxylate transporter; by homology with mammalian OAT1 transporters, C. elegans OAT-1 is predicted to function in xenobiotic elimination.
20	Y18D10A.2	Y18D10A.2	n/a	chrI 12,808,033	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
21	F07C3.2	F07C3.2	n/a	chrV 9,226,731
22	F46F5.11	F46F5.11	n/a	chrII 810,328	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
23	ZK1290.10	ZK1290.10	n/a	chrII 7,552,859	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003582 (Metridin-like ShK toxin)
24	E02C12.12	E02C12.12	n/a	chrV 9,380,457	contains similarity to Pfam domain PF07914 Protein of unknown function (DUF1679) contains similarity to Interpro domain IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species)
25	clec-154	F10F2.5	n/a	chrIII 4,639,461	C. elegans CLEC-154 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
26	srd-20	Y38A10A.1	n/a	chrV 6,056,149	C. elegans SRD-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	nhr-216	T09D3.4	n/a	chrV 5,356,451	C. elegans NHR-216 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
28	H40L08.3	H40L08.3	n/a	chrX 15,073,031	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
29	str-31	C54F6.10	n/a	chrV 7,507,570	C. elegans STR-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000539 (Frizzled protein)
30	tsp-16	F01E11.4	n/a	chrX 6,995,740	C. elegans TSP-16 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin), IPR013838 (Beta tubulin, autoregulation binding site)
31	srd-71	C13B7.4	n/a	chrV 2,424,746	C. elegans SRD-71 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001614 (Myelin proteolipid protein PLP), IPR003002 (7TM chemoreceptor, subfamily 1), IPR002016 (Haem peroxidase, plant/fungal/bacterial)
32	K03A11.4	K03A11.4	n/a	chrX 13,080,030	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
33	ZK180.1	ZK180.1	n/a	chrIV 4,497,817	contains similarity to Pfam domain PF00003 7 transmembrane receptor (metabotropic glutamate family) contains similarity to Interpro domains IPR000337 (GPCR, family 3), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)
34	F58B4.2	F58B4.2	n/a	chrV 10,918,030	contains similarity to Pfam domain PF00173 Cytochrome b5-like Heme/Steroid binding domain contains similarity to Interpro domain IPR001199 (Cytochrome b5)
35	K08D10.9	K08D10.9	n/a	chrIV 4,159,983
36	T21E8.4	T21E8.4	n/a	chrX 10,882,602	contains similarity to Rattus norvegicus Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) (G6PD).; SW:G6PD_RAT
37	C16D9.6	C16D9.6	n/a	chrV 8,249,274	contains similarity to Drosophila melanogaster Flybase gene name is CG9520-PA;; FLYBASE:CG9520
38	F26A1.3	F26A1.3	n/a	chrIII 4,827,878	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
39	T02G6.2	T02G6.2	n/a	chrI 11,801,906	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9C9Y9
40	T23G4.2	T23G4.2	n/a	chrIV 13,688,527	contains similarity to Interpro domain IPR001984 (Peptidase S16, Lon protease)
41	Y7A5A.3	Y7A5A.3	n/a	chrX 15,783,069
42	ZC155.2	ZC155.2	n/a	chrIII 5,219,635	contains similarity to Interpro domains IPR000164 (Histone H3), IPR009072 (Histone-fold)
43	srbc-56	F54B8.12	n/a	chrV 15,831,110	C. elegans SRBC-56 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
44	K03H9.1	K03H9.1	n/a	chrII 6,431,519
45	B0207.11	B0207.11	n/a	chrI 5,963,581	B0207.11 encodes a nematode-specific protein probably required for a normally high ovulation rate; B0207.11 has no obvious non-nematode homologs, but does have a putative N-terminal coiled-coil domain and an SH2 motif, and is is paralogous to four other C. elegans proteins (F42G4.6, F44F4.10, T08G11.2, and Y81G3A.1); B0207.11(tm322) hermaphrodites show abnormal egg-laying, retaining significantly fewer eggs than wild-type (perhaps due to a lowered ovulation rate) while retaining late-stage embryos; B0207.11 has no obvious phenotype in mass RNAi experiments, possibly because of genetic redundancy with its paralogs.
46	C34G6.3	C34G6.3	n/a	chrI 5,897,020	contains similarity to Interpro domain IPR005819 (Histone H5)
47	R13.4	R13.4	n/a	chrIV 10,819,150	contains similarity to Pfam domain PF02891 MIZ/SP-RING zinc finger contains similarity to Interpro domain IPR004181 (Zinc finger, MIZ-type)
48	C54E4.4	C54E4.4	n/a	chrIV 2,163,172
49	F31B9.2	F31B9.2	n/a	chrX 15,919,200	contains similarity to Mus musculus Radixin (ESP10).; SW:RADI_MOUSE
50	B0524.2	B0524.2	n/a	chrIII 1,896,968	contains similarity to Pfam domain PF01734 Patatin-like phospholipase contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin)